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ONTOLOGY REPORT - ANNOTATIONS


Term:central nervous system neuron differentiation
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Accession:GO:0021953 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.
Comment:This term was added by GO_REF:0000021.


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central nervous system neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NR4A2 nuclear receptor subfamily 4 group A member 2 JBrowse link 36 2,546,237 2,554,559 RGD:13508589
G TULP3 TUB like protein 3 JBrowse link 27 41,819,574 41,884,198 RGD:13508589
anterior commissure morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NR2E1 nuclear receptor subfamily 2 group E member 1 JBrowse link 12 65,209,177 65,230,274 RGD:13508589
G TSKU tsukushi, small leucine rich proteoglycan JBrowse link 21 21,910,333 21,927,758 RGD:13508589
Cajal-Retzius cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PSEN1 presenilin 1 JBrowse link 8 46,495,551 46,569,532 RGD:13508589
canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G WNT2 Wnt family member 2 JBrowse link 14 56,123,735 56,172,113 RGD:13508589
G WNT3 Wnt family member 3 JBrowse link 9 10,073,019 10,124,454 RGD:13508589
central nervous system neuron axonogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARHGAP35 Rho GTPase activating protein 35 JBrowse link 1 108,952,836 109,034,329 RGD:13508589
G B4GALT6 beta-1,4-galactosyltransferase 6 JBrowse link 7 57,849,872 57,917,289 RGD:13508589
G HSP90AB1 heat shock protein 90 alpha family class B member 1 JBrowse link 12 12,658,415 12,664,945 RGD:13508589
central nervous system neuron development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASCL1 achaete-scute family bHLH transcription factor 1 JBrowse link 15 41,694,021 41,696,933 RGD:13508589
G GATA2 GATA binding protein 2 JBrowse link 20 2,472,251 2,488,380 RGD:13508589
G GBA2 glucosylceramidase beta 2 JBrowse link 11 52,264,959 52,277,298 RGD:13508589
G MAP2 microtubule associated protein 2 JBrowse link 37 17,316,899 17,611,360 RGD:13508589
central nervous system projection neuron axonogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 7 42,786,505 42,797,976 RGD:13508589
G DCX doublecortin JBrowse link X 84,408,762 84,541,157 RGD:13508589
G EPHB1 EPH receptor B1 JBrowse link 23 31,485,701 31,918,754 RGD:13508589
G EPHB2 EPH receptor B2 JBrowse link 2 76,427,112 76,551,494 RGD:13508589
G EPHB3 EPH receptor B3 JBrowse link 34 17,422,746 17,433,769 RGD:13508589
G NR4A2 nuclear receptor subfamily 4 group A member 2 JBrowse link 36 2,546,237 2,554,559 RGD:13508589
cerebellar granule cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GRID2 glutamate ionotropic receptor delta type subunit 2 JBrowse link 32 15,322,256 16,787,966 RGD:13508589
G OPHN1 oligophrenin 1 JBrowse link X 52,418,390 52,983,155 RGD:13508589
G PROX1 prospero homeobox 1 JBrowse link 7 11,996,282 12,047,693 RGD:13508589
G WNT7A Wnt family member 7A JBrowse link 20 4,072,010 4,139,521 RGD:13508589
cerebellar neuron development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CRKL CRK like proto-oncogene, adaptor protein JBrowse link 26 30,542,276 30,582,479 RGD:13508589
cerebellar Purkinje cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGTPBP1 ATP/GTP binding protein 1 JBrowse link 1 73,853,491 74,030,075 RGD:13508589
G CACNA1A calcium voltage-gated channel subunit alpha1 A JBrowse link 20 48,747,087 49,036,627 RGD:13508589
G CEND1 cell cycle exit and neuronal differentiation 1 JBrowse link 18 25,782,012 25,783,897 RGD:13508589
G HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 JBrowse link 30 28,195,296 28,379,343 RGD:13508589
G LDB1 LIM domain binding 1 JBrowse link 28 14,646,409 14,658,324 RGD:13508589
G LHX1 LIM homeobox 1 JBrowse link 9 36,760,890 36,768,345 RGD:13508589
G LHX5 LIM homeobox 5 JBrowse link 26 10,776,991 10,785,820 RGD:13508589
G RORA RAR related orphan receptor A JBrowse link 30 25,315,974 26,026,708 RGD:13508589
cerebral cortex GABAergic interneuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASCL1 achaete-scute family bHLH transcription factor 1 JBrowse link 15 41,694,021 41,696,933 RGD:13508589
cerebral cortex GABAergic interneuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DLX2 distal-less homeobox 2 JBrowse link 36 16,499,009 16,502,365 RGD:13508589
cerebral cortex GABAergic interneuron migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARX aristaless related homeobox JBrowse link X 20,545,346 20,556,206 RGD:13508589
G CNTN2 contactin 2 JBrowse link 38 1,570,598 1,600,524 RGD:13508589
G DRD2 dopamine receptor D2 JBrowse link 5 19,732,842 19,795,241 RGD:13508589
G FEZF2 FEZ family zinc finger 2 JBrowse link 20 28,704,287 28,708,620 RGD:13508589
cerebral cortex neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C31H21orf91 chromosome 31 C21orf91 homolog JBrowse link 31 14,225,807 14,254,801 RGD:13508589
G EOMES eomesodermin JBrowse link 23 16,476,498 16,512,406 RGD:13508589
G ID4 inhibitor of DNA binding 4, HLH protein JBrowse link 35 18,357,751 18,358,143 RGD:13508589
G NR2E1 nuclear receptor subfamily 2 group E member 1 JBrowse link 12 65,209,177 65,230,274 RGD:13508589
G OPHN1 oligophrenin 1 JBrowse link X 52,418,390 52,983,155 RGD:13508589
G PEX5 peroxisomal biogenesis factor 5 JBrowse link 27 37,843,218 37,860,664 RGD:13508589
G SIN3A SIN3 transcription regulator family member A JBrowse link 30 38,231,844 38,306,665 RGD:13508589
commissural neuron differentiation in spinal cord term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DRAXIN dorsal inhibitory axon guidance protein JBrowse link 2 84,515,881 84,525,797 RGD:13508589
commitment of neuronal cell to specific neuron type in forebrain term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASCL1 achaete-scute family bHLH transcription factor 1 JBrowse link 15 41,694,021 41,696,933 RGD:13508589
G BCL11B BAF chromatin remodeling complex subunit BCL11B JBrowse link 8 67,622,592 67,713,922 RGD:13508589
G FEZF2 FEZ family zinc finger 2 JBrowse link 20 28,704,287 28,708,620 RGD:13508589
G GATA2 GATA binding protein 2 JBrowse link 20 2,472,251 2,488,380 RGD:13508589
G SATB2 SATB homeobox 2 JBrowse link 37 8,548,295 8,837,416 RGD:13508589
G TBR1 T-box brain transcription factor 1 JBrowse link 36 6,989,644 6,997,916 RGD:13508589
corpus callosum morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C27H12orf57 chromosome 27 C12orf57 homolog JBrowse link 27 38,101,705 38,103,553 RGD:13508589
G NIN ninein JBrowse link 8 27,100,740 27,199,269 RGD:13508589
G TSKU tsukushi, small leucine rich proteoglycan JBrowse link 21 21,910,333 21,927,758 RGD:13508589
corticospinal neuron axon guidance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SCN1B sodium voltage-gated channel beta subunit 1 JBrowse link 1 117,504,428 117,510,666 RGD:13508589
corticospinal tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDH11 cadherin 11 JBrowse link 5 83,977,267 84,122,712 RGD:13508589
G EPHA4 EPH receptor A4 JBrowse link 37 27,670,143 27,809,642 RGD:13508589
G NIN ninein JBrowse link 8 27,100,740 27,199,269 RGD:13508589
efferent axon development in a lateral line nerve term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PHOX2B paired like homeobox 2B JBrowse link 13 38,865,963 38,869,912 RGD:13508589
embryonic olfactory bulb interneuron precursor migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARX aristaless related homeobox JBrowse link X 20,545,346 20,556,206 RGD:13508589
forebrain neuron development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GBX2 gastrulation brain homeobox 2 JBrowse link 25 47,005,509 47,008,367 RGD:13508589
G LHX6 LIM homeobox 6 JBrowse link 9 60,348,529 60,374,037 RGD:13508589
G LHX8 LIM homeobox 8 JBrowse link 6 71,329,711 71,355,851 RGD:13508589
G RAPGEF2 Rap guanine nucleotide exchange factor 2 JBrowse link 15 56,133,094 56,353,609 RGD:13508589
forebrain neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LHX5 LIM homeobox 5 JBrowse link 26 10,776,991 10,785,820 RGD:13508589
G POU3F4 POU class 3 homeobox 4 JBrowse link X 64,427,161 64,428,825 RGD:13508589
gonadotrophin-releasing hormone neuronal migration to the hypothalamus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SEMA3A semaphorin 3A JBrowse link 18 23,411,607 23,866,631 RGD:13508589
medial motor column neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LHX3 LIM homeobox 3 JBrowse link 9 49,248,555 49,254,128 RGD:13508589
midbrain dopaminergic neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CTNNB1 catenin beta 1 JBrowse link 23 10,559,722 10,572,933 RGD:13508589
G LMX1A LIM homeobox transcription factor 1 alpha JBrowse link 38 17,958,366 18,111,155 RGD:13508589
non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G WNT9B Wnt family member 9B JBrowse link 9 10,157,607 10,172,664 RGD:13508589
olfactory bulb interneuron development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SALL3 spalt like transcription factor 3 JBrowse link 1 1,413,991 1,421,516 RGD:13508589
G WNT5A Wnt family member 5A JBrowse link 20 34,756,430 34,790,937 RGD:13508589
olfactory bulb interneuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DLX5 distal-less homeobox 5 JBrowse link 14 22,080,351 22,085,188 RGD:13508589
G UNCX UNC homeobox JBrowse link 6 15,652,600 15,657,016 RGD:13508589
positive regulation of forebrain neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PROX1 prospero homeobox 1 JBrowse link 7 11,996,282 12,047,693 RGD:13508589
positive regulation of midbrain dopaminergic neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DKK1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 26 35,697,428 35,701,596 RGD:13508589
pyramidal neuron development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DCLK2 doublecortin like kinase 2 JBrowse link 15 48,119,227 48,365,807 RGD:13508589
G DCX doublecortin JBrowse link X 84,408,762 84,541,157 RGD:13508589
G PLXNA3 plexin A3 JBrowse link X 122,165,460 122,180,727 RGD:13508589
G UQCRQ ubiquinol-cytochrome c reductase complex III subunit VII JBrowse link 11 21,148,964 21,150,573 RGD:13508589
pyramidal neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G UNC5D unc-5 netrin receptor D JBrowse link 16 29,204,364 29,733,726 RGD:13508589
regulation of forebrain neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GATA2 GATA binding protein 2 JBrowse link 20 2,472,251 2,488,380 RGD:13508589
regulation of midbrain dopaminergic neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SFRP2 secreted frizzled related protein 2 JBrowse link 15 51,541,197 51,548,765 RGD:13508589
regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DLX2 distal-less homeobox 2 JBrowse link 36 16,499,009 16,502,365 RGD:13508589
regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LBX1 ladybird homeobox 1 JBrowse link 28 13,872,846 13,875,521 RGD:13508589
retrotrapezoid nucleus neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PHOX2B paired like homeobox 2B JBrowse link 13 38,865,963 38,869,912 RGD:13508589
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GLI2 GLI family zinc finger 2 JBrowse link 19 29,128,401 29,383,324 RGD:13508589
G GLI3 GLI family zinc finger 3 JBrowse link 18 7,800,817 8,071,531 RGD:13508589
G SUFU SUFU negative regulator of hedgehog signaling JBrowse link 28 14,992,989 15,115,499 RGD:13508589
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GLI2 GLI family zinc finger 2 JBrowse link 19 29,128,401 29,383,324 RGD:13508589
G GLI3 GLI family zinc finger 3 JBrowse link 18 7,800,817 8,071,531 RGD:13508589
G SUFU SUFU negative regulator of hedgehog signaling JBrowse link 28 14,992,989 15,115,499 RGD:13508589
somatic motor neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLN8 CLN8 transmembrane ER and ERGIC protein JBrowse link 37 30,863,098 30,885,831 RGD:13508589
spinal cord association neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASCL1 achaete-scute family bHLH transcription factor 1 JBrowse link 15 41,694,021 41,696,933 RGD:13508589
G GSX1 GS homeobox 1 JBrowse link 25 11,853,483 11,855,169 RGD:13508589
G LHX1 LIM homeobox 1 JBrowse link 9 36,760,890 36,768,345 RGD:13508589
G LHX3 LIM homeobox 3 JBrowse link 9 49,248,555 49,254,128 RGD:13508589
G LHX5 LIM homeobox 5 JBrowse link 26 10,776,991 10,785,820 RGD:13508589
G WNT3A Wnt family member 3A JBrowse link 14 864,393 899,698 RGD:13508589
spinal cord motor neuron cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HOXC10 homeobox C10 JBrowse link 27 1,272,272 1,277,411 RGD:13508589
G HOXD10 homeobox D10 JBrowse link 36 19,924,352 19,927,706 RGD:13508589
G ISL1 ISL LIM homeobox 1 JBrowse link 4 63,638,009 63,648,492 RGD:13508589
G LHX3 LIM homeobox 3 JBrowse link 9 49,248,555 49,254,128 RGD:13508589
G MNX1 motor neuron and pancreas homeobox 1 JBrowse link 16 19,509,038 19,514,378 RGD:13508589
G OLIG3 oligodendrocyte transcription factor 3 JBrowse link 1 29,919,043 29,921,713 RGD:13508589
spinal cord motor neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABT1 activator of basal transcription 1 JBrowse link 35 24,357,502 24,360,731 RGD:13508589
G CACNA1A calcium voltage-gated channel subunit alpha1 A JBrowse link 20 48,747,087 49,036,627 RGD:13508589
G DYNC2H1 dynein cytoplasmic 2 heavy chain 1 JBrowse link 5 28,566,604 28,727,416 RGD:13508589
G GIGYF2 GRB10 interacting GYF protein 2 JBrowse link 25 44,317,540 44,453,761 RGD:13508589
G IFT172 intraflagellar transport 172 JBrowse link 17 21,389,462 21,426,970 RGD:13508589
G LBX1 ladybird homeobox 1 JBrowse link 28 13,872,846 13,875,521 RGD:13508589
G NFE2L1 nuclear factor, erythroid 2 like 1 JBrowse link 9 24,344,697 24,356,918 RGD:13508589
G OLIG2 oligodendrocyte transcription factor 2 JBrowse link 31 27,674,112 27,677,521 RGD:13508589
spinal cord ventral commissure morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADARB1 adenosine deaminase RNA specific B1 JBrowse link 31 38,715,529 38,799,353 RGD:13508589
G DCC DCC netrin 1 receptor JBrowse link 1 21,788,833 22,494,849 RGD:13508589
G GLI2 GLI family zinc finger 2 JBrowse link 19 29,128,401 29,383,324 RGD:13508589
striatal medium spiny neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL11B BAF chromatin remodeling complex subunit BCL11B JBrowse link 8 67,622,592 67,713,922 RGD:13508589
G INHBA inhibin subunit beta A JBrowse link 18 8,272,978 8,288,432 RGD:13508589
ventral spinal cord interneuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GATA2 GATA binding protein 2 JBrowse link 20 2,472,251 2,488,380 RGD:13508589
ventral spinal cord interneuron fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASCL1 achaete-scute family bHLH transcription factor 1 JBrowse link 15 41,694,021 41,696,933 RGD:13508589
G DLL4 delta like canonical Notch ligand 4 JBrowse link 30 8,059,463 8,068,742 RGD:13508589
G FOXN4 forkhead box N4 JBrowse link 26 17,730,638 17,757,173 RGD:13508589
ventral spinal cord interneuron specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LHX3 LIM homeobox 3 JBrowse link 9 49,248,555 49,254,128 RGD:13508589
visceral motor neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ISL1 ISL LIM homeobox 1 JBrowse link 4 63,638,009 63,648,492 RGD:13508589
G TBX20 T-box transcription factor 20 JBrowse link 14 46,891,706 46,946,899 RGD:13508589
Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G WNT5A Wnt family member 5A JBrowse link 20 34,756,430 34,790,937 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13038
    cellular process 11437
      cellular developmental process 2201
        cell differentiation 2085
          neuron differentiation 729
            central nervous system neuron differentiation 96
              Lugaro cell differentiation 0
              candelabrum cell differentiation 0
              central nervous system neuron development + 39
              cerebellar Golgi cell differentiation 0
              cerebellar Purkinje cell differentiation 8
              cerebellar basket cell differentiation 0
              cerebellar granule cell differentiation 4
              cerebellar stellate cell differentiation 0
              cerebellar unipolar brush cell differentiation 0
              cerebral cortex neuron differentiation + 14
              commissural neuron differentiation in spinal cord + 1
              eurydendroid cell differentiation 0
              forebrain neuron differentiation + 27
              midbrain dopaminergic neuron differentiation + 8
              pyramidal neuron differentiation + 5
              retrotrapezoid nucleus neuron differentiation 1
              spinal cord association neuron differentiation + 7
              spinal cord motor neuron differentiation + 19
              ventral spinal cord interneuron differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 13038
    developmental process 3272
      anatomical structure development 3009
        multicellular organism development 2647
          system development 2434
            nervous system development 1195
              neurogenesis 876
                generation of neurons 823
                  neuron differentiation 729
                    central nervous system neuron differentiation 96
                      Lugaro cell differentiation 0
                      candelabrum cell differentiation 0
                      central nervous system neuron development + 39
                      cerebellar Golgi cell differentiation 0
                      cerebellar Purkinje cell differentiation 8
                      cerebellar basket cell differentiation 0
                      cerebellar granule cell differentiation 4
                      cerebellar stellate cell differentiation 0
                      cerebellar unipolar brush cell differentiation 0
                      cerebral cortex neuron differentiation + 14
                      commissural neuron differentiation in spinal cord + 1
                      eurydendroid cell differentiation 0
                      forebrain neuron differentiation + 27
                      midbrain dopaminergic neuron differentiation + 8
                      pyramidal neuron differentiation + 5
                      retrotrapezoid nucleus neuron differentiation 1
                      spinal cord association neuron differentiation + 7
                      spinal cord motor neuron differentiation + 19
                      ventral spinal cord interneuron differentiation + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.