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ONTOLOGY REPORT - ANNOTATIONS


Term:corticospinal tract morphogenesis
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Accession:GO:0021957 term browser browse the term
Definition:Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract.
Synonyms:exact_synonym: CST axonogenesis;   corticospinal tract axonogenesis


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corticospinal tract morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe22 basic helix-loop-helix family, member e22 ISO MGI:2684610|MGI:4440742|MGI:4440744|MGI:99217 (MGI:5315201|PMID:22284184) RGD PMID:22284184 MGI:5315201 NCBI chr 2:102,685,513...102,688,624
Ensembl chr 2:102,685,513...102,688,624
JBrowse link
G Cdh11 cadherin 11 ISO MGI:1930001 (MGI:5315201|PMID:22284184) RGD PMID:22284184 MGI:5315201 NCBI chr19:2,391,181...2,551,245
Ensembl chr19:2,393,059...2,551,245
JBrowse link
G Epha4 Eph receptor A4 ISS
ISO
GO_REF:0000024
(MGI:1306963|PMID:9789074)
UniProt
RGD
PMID:9789074 GO_REF:0000024, MGI:1306963 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Fbxo45 F-box protein 45 IEA
ISO
GO_REF:0000107
MGI:3849742 (MGI:3849342|PMID:19398581)
Ensembl
RGD
PMID:19398581 GO_REF:0000107, MGI:3849342 NCBI chr11:71,795,977...71,811,858
Ensembl chr11:71,796,282...71,808,498
JBrowse link
G Nin ninein ISO MGI:1344407 (MGI:5629993|PMID:25741725) RGD PMID:25741725 MGI:5629993 NCBI chr 6:92,423,412...92,527,776
Ensembl chr 6:92,433,381...92,527,711
JBrowse link
G Prdm8 PR/SET domain 8 ISO MGI:5315763 (MGI:5315201|PMID:22284184) RGD PMID:22284184 MGI:5315201 NCBI chr14:13,052,776...13,073,583
Ensembl chr14:13,054,771...13,058,172
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 ISO MGI:2387499|MGI:2668659 (MGI:5629993|PMID:25741725) RGD PMID:25741725 MGI:5629993 NCBI chr 3:29,857,289...29,985,932
Ensembl chr 3:29,862,473...29,996,865
JBrowse link
corticospinal neuron axon guidance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn1b sodium voltage-gated channel beta subunit 1 ISO MGI:3043422 (MGI:3778100|PMID:18354028) RGD PMID:18354028 MGI:3778100 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
corticospinal neuron axon guidance through spinal cord term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slit2 slit guidance ligand 2 ISO
IEA
(PMID:10975526)
GO_REF:0000107
RGD
Ensembl
PMID:10975526 GO_REF:0000107 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        cell development 2442
          neuron development 1323
            central nervous system neuron development 101
              central nervous system neuron axonogenesis 42
                central nervous system projection neuron axonogenesis 29
                  corticospinal tract morphogenesis 9
                    corticospinal neuron axon guidance + 2
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            nervous system development 2719
              neurogenesis 1936
                generation of neurons 1780
                  neuron differentiation 1614
                    neuron development 1323
                      neuron projection development 1164
                        neuron projection morphogenesis 722
                          axonogenesis 496
                            central nervous system neuron axonogenesis 42
                              central nervous system projection neuron axonogenesis 29
                                corticospinal tract morphogenesis 9
                                  corticospinal neuron axon guidance + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.