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ONTOLOGY REPORT - ANNOTATIONS


Term:extracellular matrix disassembly
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Accession:GO:0022617 term browser browse the term
Definition:A process that results in the breakdown of the extracellular matrix.


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extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Capg capping actin protein, gelsolin like NOT ISO (PMID:24236012) RGD PMID:24236012 NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446
JBrowse link
G Cma1 chymase 1 ISO (PMID:27068509) RGD PMID:27068509 NCBI chr15:34,601,037...34,603,819
Ensembl chr15:34,601,037...34,603,819
JBrowse link
G Eng endoglin ISO (PMID:18223685) RGD PMID:18223685 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Exoc8 exocyst complex component 8 ISO (PMID:24344185) RGD PMID:24344185 NCBI chr19:57,647,305...57,649,794
Ensembl chr19:57,647,291...57,649,827
JBrowse link
G Flot1 flotillin 1 ISO (PMID:21119006) RGD PMID:21119006 NCBI chr20:3,427,890...3,438,418
Ensembl chr20:3,427,880...3,438,396
JBrowse link
G Gsn gelsolin NOT ISO (PMID:24236012) RGD PMID:24236012 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Kif9 kinesin family member 9 ISO (PMID:21119006) RGD PMID:21119006 NCBI chr 8:118,737,739...118,795,190
Ensembl chr 8:118,744,229...118,794,992
JBrowse link
G Klk4 kallikrein-related peptidase 4 ISO
IBA
MGI:MGI:4355346 (MGI:MGI:5502300|PMID:22243248)
PMID:21873635
RGD PMID:22243248, PMID:21873635 MGI:MGI:5502300, RGD:13792537 NCBI chr 1:99,828,944...99,834,642
Ensembl chr 1:99,829,351...99,834,216
JBrowse link
G Klk5 kallikrein related-peptidase 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:99,781,291...99,793,745
Ensembl chr 1:99,781,237...99,786,330
JBrowse link
G Lamc1 laminin subunit gamma 1 ISO (PMID:15159456) RGD PMID:15159456 NCBI chr13:70,656,727...70,783,515
Ensembl chr13:70,658,707...70,783,515
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 ISO (PMID:24236012) RGD PMID:24236012 NCBI chr15:57,170,566...57,277,811
Ensembl chr15:57,221,292...57,277,811
JBrowse link
G Mmp13 matrix metallopeptidase 13 IEA
ISO
ISS
GO_REF:0000107
(PMID:8576151), (PMID:9065415)
GO_REF:0000024
(MGI:MGI:3771509|PMID:17987127)
Ensembl
RGD
UniProt
PMID:8576151, PMID:9065415, PMID:17987127 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3771509 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp20 matrix metallopeptidase 20 ISO MGI:MGI:2447874 (MGI:MGI:5502300|PMID:22243248) RGD PMID:22243248 MGI:MGI:5502300 NCBI chr 8:5,823,147...5,875,555
Ensembl chr 8:5,833,359...5,875,232
JBrowse link
G Noxo1 NADPH oxidase organizer 1 ISO (PMID:19755710) RGD PMID:19755710 NCBI chr10:14,062,331...14,066,918
Ensembl chr10:14,062,331...14,066,918
JBrowse link
G Plg plasminogen ISO (PMID:14699093) RGD PMID:14699093 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Sh3pxd2b SH3 and PX domains 2B ISO (PMID:19755710) RGD PMID:19755710 NCBI chr10:17,209,152...17,296,449
Ensembl chr10:17,209,212...17,291,876
JBrowse link
G Tpsab1 tryptase alpha/beta 1 ISO (PMID:27068509) RGD PMID:27068509 NCBI chr10:14,701,253...14,703,668
Ensembl chr10:14,701,253...14,703,668
JBrowse link
G Washc1 WASH complex subunit 1 ISO (PMID:24344185) RGD PMID:24344185 NCBI chr 9:113,918,914...113,936,861
Ensembl chr 9:113,918,858...113,936,860
JBrowse link
G Wdr72 WD repeat domain 72 ISO MGI:MGI:5913851 (MGI:MGI:5906533|PMID:26247047) RGD PMID:26247047 MGI:MGI:5906533 NCBI chr 8:80,965,734...81,125,710
Ensembl chr 8:80,965,255...81,039,246
JBrowse link
basement membrane disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cma1 chymase 1 ISO (PMID:27068509) RGD PMID:27068509 NCBI chr15:34,601,037...34,603,819
Ensembl chr15:34,601,037...34,603,819
JBrowse link
G Ctss cathepsin S ISO
IEA
(PMID:22952693)
GO_REF:0000107
(MGI:MGI:5553237|PMID:22952693)
RGD
Ensembl
PMID:22952693 GO_REF:0000107, MGI:MGI:5553237 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Hpn hepsin IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:16908524)
Ensembl
UniProt
RGD
PMID:16908524 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:89,534,112...89,549,575
Ensembl chr 1:89,534,106...89,543,967
JBrowse link
negative regulation of extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C ISO (PMID:10545518) RGD PMID:10545518 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
G Dpp4 dipeptidylpeptidase 4 ISO
ISS
(PMID:16651416)
GO_REF:0000024
RGD
UniProt
PMID:16651416 GO_REF:0000024 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Fap fibroblast activation protein, alpha ISO (PMID:16651416) RGD PMID:16651416 NCBI chr 3:48,467,781...48,536,242
Ensembl chr 3:48,467,781...48,536,235
JBrowse link
positive regulation of extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil2 capping protein regulator and myosin 1 linker 2 ISO (PMID:26466680), (PMID:26578515) RGD PMID:26466680, PMID:26578515 NCBI chr19:37,652,383...37,665,333
Ensembl chr19:37,652,969...37,668,019
JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 ISO (PMID:24859005) RGD PMID:24859005 NCBI chr13:34,365,038...34,584,651
Ensembl chr13:34,365,147...34,584,651
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 ISO
IEA
(PMID:24859005)
GO_REF:0000107
RGD
Ensembl
PMID:24859005 GO_REF:0000107 NCBI chr 8:122,003,719...122,185,495
Ensembl chr 8:122,003,916...122,185,495
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO (MGI:MGI:2158097|PMID:11723120) RGD PMID:11723120 MGI:MGI:2158097 NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
JBrowse link
G Fscn1 fascin actin-bundling protein 1 ISO
ISS
IEA
(PMID:20137952)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:20137952 GO_REF:0000024, GO_REF:0000107 NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515
JBrowse link
G Il6 interleukin 6 ISO (PMID:26587789) RGD PMID:26587789 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Meltf melanotransferrin ISO (PMID:16713448) RGD PMID:16713448 NCBI chr11:72,135,311...72,158,106
Ensembl chr11:72,135,668...72,157,522
JBrowse link
G Pdpn podoplanin ISO
IBA
ISS
(PMID:25486435)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:25486435, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO (MGI:MGI:5688835|PMID:21984612) RGD PMID:21984612 MGI:MGI:5688835 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
regulation of extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddr1 discoidin domain receptor tyrosine kinase 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:3629583|PMID:12065315)
(PMID:12065315)
Ensembl
UniProt
RGD
PMID:12065315 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3629583 NCBI chr20:3,553,430...3,574,959
Ensembl chr20:3,552,929...3,575,780
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor IMP RGD PMID:16738537 RGD:2313717 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 ISO
ISS
(PMID:20876804)
GO_REF:0000024
RGD
UniProt
PMID:20876804 GO_REF:0000024 NCBI chr17:9,990,072...10,004,339
Ensembl chr17:9,990,078...10,004,321
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          cellular component disassembly 425
            extracellular matrix disassembly 36
              basement membrane disassembly + 3
              biofilm matrix disassembly 0
              negative regulation of extracellular matrix disassembly 3
              positive regulation of extracellular matrix disassembly 9
              regulation of extracellular matrix disassembly + 15
Path 2
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          extracellular structure organization 316
            extracellular matrix organization 315
              extracellular matrix disassembly 36
                basement membrane disassembly + 3
                biofilm matrix disassembly 0
                negative regulation of extracellular matrix disassembly 3
                positive regulation of extracellular matrix disassembly 9
                regulation of extracellular matrix disassembly + 15
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.