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ONTOLOGY REPORT - ANNOTATIONS


Term:CCR4-NOT complex
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Accession:GO:0030014 term browser browse the term
Definition:The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8.


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CCR4-NOT complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnot1 CCR4-NOT transcription complex, subunit 1 JBrowse link 19 9,668,186 9,761,605 RGD:1624291
G Cnot10 CCR4-NOT transcription complex, subunit 10 JBrowse link 8 122,634,681 122,696,466 RGD:1600115
RGD:13792537
RGD:1624291
G Cnot11 CCR4-NOT transcription complex, subunit 11 JBrowse link 9 46,270,229 46,279,928 RGD:1600115
RGD:1624291
G Cnot2 CCR4-NOT transcription complex, subunit 2 JBrowse link 7 59,526,105 59,617,307 RGD:1624291
G Cnot3 CCR4-NOT transcription complex, subunit 3 JBrowse link 1 64,130,823 64,147,066 RGD:1624291
G Cnot4 CCR4-NOT transcription complex, subunit 4 JBrowse link 4 62,561,443 62,663,225 RGD:1624291
RGD:13792537
G Cnot6 CCR4-NOT transcription complex, subunit 6 JBrowse link 10 35,144,291 35,195,126 RGD:1624291
RGD:1600115
RGD:13792537
G Cnot6l CCR4-NOT transcription complex, subunit 6-like JBrowse link 14 15,059,101 15,148,255 RGD:1624291
RGD:13792537
G Cnot7 CCR4-NOT transcription complex, subunit 7 JBrowse link 16 54,899,452 54,918,616 RGD:1624291
G Cnot8 CCR4-NOT transcription complex, subunit 8 JBrowse link 10 43,538,150 43,551,271 RGD:1624291
G Cnot9 CCR4-NOT transcription complex subunit 9 JBrowse link 9 81,783,349 81,808,815 RGD:1624291
RGD:1600115
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 1 255,660,165 255,842,671 RGD:1624291
G Patl1 PAT1 homolog 1, processing body mRNA decay factor JBrowse link 1 228,337,756 228,369,719 RGD:1624291
RGD:1600115
G Tnks1bp1 tankyrase 1 binding protein 1 JBrowse link 3 72,458,520 72,483,206 RGD:1624291
G Tob1 transducer of ErbB-2.1 JBrowse link 10 81,913,689 81,915,727 RGD:1600115
RGD:1624291
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1600115
RGD:1624291
CCR4-NOT core complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnot1 CCR4-NOT transcription complex, subunit 1 JBrowse link 19 9,668,186 9,761,605 RGD:13792537
G Cnot2 CCR4-NOT transcription complex, subunit 2 JBrowse link 7 59,526,105 59,617,307 RGD:13792537
G Cnot3 CCR4-NOT transcription complex, subunit 3 JBrowse link 1 64,130,823 64,147,066 RGD:13792537
G Cnot7 CCR4-NOT transcription complex, subunit 7 JBrowse link 16 54,899,452 54,918,616 RGD:13792537
G Cnot8 CCR4-NOT transcription complex, subunit 8 JBrowse link 10 43,538,150 43,551,271 RGD:13792537
G Cnot9 CCR4-NOT transcription complex subunit 9 JBrowse link 9 81,783,349 81,808,815 RGD:13792537

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  cellular_component 19843
    protein-containing complex 5779
      CCR4-NOT complex 16
        CCR4-NOT core complex 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.