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ONTOLOGY REPORT - ANNOTATIONS


Term:insulin secretion
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Accession:GO:0030073 term browser browse the term
Definition:The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.
Comment:Updated definition, added taxon constraint https://github.com/geneontology/go-ontology/issues/11255#issuecomment-426191045


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insulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr2b activin A receptor type 2B JBrowse link 8 128,087,308 128,126,776 RGD:1624291
RGD:1600115
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:1624291
RGD:1600115
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:628365
RGD:13792537
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1624291
G Cckar cholecystokinin A receptor JBrowse link 14 59,610,939 59,619,786 RGD:2313338
G Cplx1 complexin 1 JBrowse link 14 2,194,895 2,226,610 RGD:1624291
RGD:1600115
G Cplx3 complexin 3 JBrowse link 8 62,379,502 62,386,264 RGD:1624291
RGD:1600115
G Cyb5r4 cytochrome b5 reductase 4 JBrowse link 8 94,693,273 94,757,989 RGD:1624291
RGD:1600115
G Dgat1 diacylglycerol O-acyltransferase 1 JBrowse link 7 117,566,363 117,576,735 RGD:628375
G Fam3b FAM3 metabolism regulating signaling molecule B JBrowse link 11 37,922,308 37,993,279 RGD:1624291
RGD:13792537
G Ffar1 free fatty acid receptor 1 JBrowse link 1 89,308,475 89,309,379 RGD:1624291
RGD:1600115
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
RGD:1600115
G Glp1r glucagon-like peptide 1 receptor JBrowse link 20 9,586,075 9,626,228 RGD:8553736
G Gpr119 G protein-coupled receptor 119 JBrowse link X 135,515,545 135,521,598 RGD:1624291
G Hnf1a HNF1 homeobox A JBrowse link 12 47,407,811 47,433,342 RGD:1624291
RGD:1600115
G Hnf1b HNF1 homeobox B JBrowse link 10 71,159,863 71,218,902 RGD:1624291
RGD:1600115
G Htt huntingtin JBrowse link 14 81,105,139 81,254,637 RGD:1624291
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:1624291
G Ildr2 immunoglobulin-like domain containing receptor 2 JBrowse link 13 84,474,191 84,532,347 RGD:1624291
RGD:1600115
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:1624291
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:1624291
RGD:1600115
G Mafa MAF bZIP transcription factor A JBrowse link 7 116,779,368 116,781,815 RGD:1624291
RGD:1600115
G Mc4r melanocortin 4 receptor JBrowse link 18 62,612,838 62,614,725 RGD:1624291
RGD:1600115
G Myo5a myosin VA JBrowse link 8 82,038,966 82,156,507 RGD:1624291
RGD:1600115
G Neurod1 neuronal differentiation 1 JBrowse link 3 66,414,314 66,417,617 RGD:1624291
RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Pclo piccolo (presynaptic cytomatrix protein) JBrowse link 4 16,454,904 17,058,921 RGD:1624291
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:1624291
RGD:1600115
G Ptprn protein tyrosine phosphatase, receptor type, N JBrowse link 9 82,446,626 82,462,314 RGD:1624291
G Rapgef4 Rap guanine nucleotide exchange factor 4 JBrowse link 3 58,632,338 58,925,127 RGD:1600115
RGD:1624291
G Rims2 regulating synaptic membrane exocytosis 2 JBrowse link 7 78,091,998 78,594,164 RGD:1600115
RGD:1624291
G Slc18a2 solute carrier family 18 member A2 JBrowse link 1 280,397,831 280,457,968 RGD:2317338
G Slc30a8 solute carrier family 30 member 8 JBrowse link 7 91,832,988 91,869,329 RGD:2315022
RGD:13792537
RGD:1624291
G Smad2 SMAD family member 2 JBrowse link 18 72,550,107 72,612,078 RGD:1624291
RGD:1600115
G Snx19 sorting nexin 19 JBrowse link 8 31,497,034 31,534,077 RGD:1624291
RGD:1600115
G Stx1a syntaxin 1A JBrowse link 12 24,682,050 24,710,002 RGD:1600115
RGD:1624291
G Stxbp3 syntaxin binding protein 3 JBrowse link 2 211,595,763 211,638,756 RGD:1624291
RGD:1600115
G Vgf VGF nerve growth factor inducible JBrowse link 12 22,677,302 22,680,630 RGD:1624291
insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptprn protein tyrosine phosphatase, receptor type, N JBrowse link 9 82,446,626 82,462,314 RGD:1600115
RGD:1624291
G Ptprn2 protein tyrosine phosphatase, receptor type N2 JBrowse link 6 144,384,773 145,133,042 RGD:1624291
RGD:1600115
G Rab11b RAB11B, member RAS oncogene family JBrowse link 7 18,598,991 18,612,132 RGD:1624291
RGD:1600115
G Rab11fip2 RAB11 family interacting protein 2 JBrowse link 1 281,065,346 281,101,163 RGD:1624291
RGD:1600115
G Rab11fip5 RAB11 family interacting protein 5 JBrowse link 4 117,113,067 117,154,495 RGD:1624291
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 4 147,532,040 147,592,769 RGD:1624291
RGD:1600115
G Rbm4 RNA binding motif protein 4 JBrowse link 1 220,038,403 220,049,756 RGD:1624291
G Selenot selenoprotein T JBrowse link 2 148,765,412 148,781,080 RGD:1624291
RGD:1600115
negative regulation of insulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc8 ATP binding cassette subfamily C member 8 JBrowse link 1 102,110,708 102,191,287 RGD:1598646
G Acvr1c activin A receptor type 1C JBrowse link 3 44,272,859 44,342,501 RGD:1624291
RGD:1600115
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:1624291
G Bmp8a bone morphogenetic protein 8a JBrowse link 5 141,007,462 141,033,511 RGD:1624291
G Ccn3 cellular communication network factor 3 JBrowse link 7 94,375,134 94,382,154 RGD:1624291
RGD:1600115
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:2311570
G Enho energy homeostasis associated JBrowse link 5 58,018,039 58,019,836 RGD:1624291
RGD:1600115
G Fam3d FAM3 metabolism regulating signaling molecule D JBrowse link 15 18,321,757 18,357,252 RGD:1624291
RGD:1600115
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:1624291
RGD:8553721
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:8553721
G Hadh hydroxyacyl-CoA dehydrogenase JBrowse link 2 236,353,445 236,395,067 RGD:2302227
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:9590127
G Inhbb inhibin subunit beta B JBrowse link 13 35,436,532 35,442,222 RGD:1624291
RGD:1600115
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:1624291
RGD:1600115
RGD:729325
G Kcnb1 potassium voltage-gated channel subfamily B member 1 JBrowse link 3 163,850,785 163,935,610 RGD:1600115
RGD:1624291
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 JBrowse link 1 102,103,093 102,107,134 RGD:1624291
RGD:1600115
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1581603
G Midn midnolin JBrowse link 7 12,414,303 12,426,712 RGD:8655525
G Mtnr1a melatonin receptor 1A JBrowse link 16 50,339,358 50,358,809 RGD:9686057
G Mtnr1b melatonin receptor 1B JBrowse link 8 14,359,270 14,373,894 RGD:9588673
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:1642149
G Npff neuropeptide FF-amide peptide precursor JBrowse link 7 144,127,084 144,127,873 RGD:2316580
G Pde8b phosphodiesterase 8B JBrowse link 2 24,718,548 24,955,533 RGD:2312519
G Pfkl phosphofructokinase, liver type JBrowse link 20 11,393,860 11,415,889 RGD:1624291
RGD:1600115
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:2316628
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291
RGD:1600115
G Psmd9 proteasome 26S subunit, non-ATPase 9 JBrowse link 12 38,786,539 38,805,121 RGD:8554418
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:10043332
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:1624291
RGD:1600115
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:1600115
RGD:1624291
G Rptor regulatory associated protein of MTOR, complex 1 JBrowse link 10 108,750,620 109,058,691 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291
G Sirt4 sirtuin 4 JBrowse link 12 46,862,358 46,876,593 RGD:1624291
RGD:1600115
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:1624291
RGD:1600115
G Stxbp5l syntaxin binding protein 5-like JBrowse link 11 66,246,624 66,566,331 RGD:1624291
RGD:1600115
G Sytl4 synaptotagmin-like 4 JBrowse link X 104,763,961 104,814,152 RGD:1624291
RGD:1600115
G Uts2 urotensin 2 JBrowse link 5 168,078,748 168,084,133 RGD:2306798
G Vsnl1 visinin-like 1 JBrowse link 6 37,001,360 37,121,969 RGD:1624291
RGD:1600115
negative regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:1624291
RGD:1600115
RGD:2316628
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:2306172
G Eny2 ENY2, transcription and export complex 2 subunit JBrowse link 7 83,348,656 83,358,430 RGD:9590329
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
RGD:1600115
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:5508687
G Jagn1 jagunal homolog 1 JBrowse link 4 145,399,885 145,404,605 RGD:11520872
G Klf7 Kruppel like factor 7 JBrowse link 9 70,740,480 70,787,913 RGD:1624291
G LOC259246 alpha-2u globulin PGCL1 RGD:1600115
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 JBrowse link 9 46,657,444 46,782,545 RGD:7495848
G Ndufaf2 NADH:ubiquinone oxidoreductase complex assembly factor 2 JBrowse link 2 39,322,145 39,434,535 RGD:1624291
RGD:1600115
G Pde1c phosphodiesterase 1C JBrowse link 4 86,359,762 86,925,044 RGD:2302857
G Pde3b phosphodiesterase 3B JBrowse link 1 183,892,841 184,078,071 RGD:2302857
G Pde4c phosphodiesterase 4C JBrowse link 16 20,442,305 20,466,386 RGD:2302857
G Pde8b phosphodiesterase 8B JBrowse link 2 24,718,548 24,955,533 RGD:2302857
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase JBrowse link 7 129,856,467 129,863,441 RGD:1624291
RGD:1600115
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 JBrowse link 3 79,734,961 79,743,737 RGD:12904047
G Ucp2 uncoupling protein 2 JBrowse link 1 165,506,375 165,512,744 RGD:7204422
positive regulation of insulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aacs acetoacetyl-CoA synthetase JBrowse link 12 36,512,393 36,555,694 RGD:2301019
G Abat 4-aminobutyrate aminotransferase JBrowse link 10 7,093,406 7,200,439 RGD:9588550
G Acsl4 acyl-CoA synthetase long-chain family member 4 JBrowse link X 113,596,247 113,660,024 RGD:14695075
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291
RGD:1600115
G Blk BLK proto-oncogene, Src family tyrosine kinase JBrowse link 15 46,555,552 46,593,778 RGD:1624291
RGD:1600115
G Capn10 calpain 10 JBrowse link 9 100,104,000 100,112,833 RGD:1624291
RGD:1600115
G Cask calcium/calmodulin dependent serine protein kinase JBrowse link X 9,815,652 10,156,155 RGD:11576293
G Casr calcium-sensing receptor JBrowse link 11 67,188,204 67,262,261 RGD:7205453
G Cd38 CD38 molecule JBrowse link 14 71,714,768 71,754,990 RGD:2307276
G Doc2b double C2 domain beta JBrowse link 10 63,921,255 63,952,944 RGD:1600115
RGD:1624291
G Ffar1 free fatty acid receptor 1 JBrowse link 1 89,308,475 89,309,379 RGD:2315053
RGD:1600115
RGD:1624291
G Gck glucokinase JBrowse link 14 86,149,146 86,191,589 RGD:1581879
RGD:1600115
RGD:1624291
RGD:2301916
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:8554453
G Gip gastric inhibitory polypeptide JBrowse link 10 83,835,080 83,848,399 RGD:2312537
G Gipr gastric inhibitory polypeptide receptor JBrowse link 1 80,063,047 80,073,223 RGD:2312607
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:8662441
G Glp1r glucagon-like peptide 1 receptor JBrowse link 20 9,586,075 9,626,228 RGD:625448
G Glrx glutaredoxin JBrowse link 2 2,606,032 2,615,944 RGD:9686053
G Glud1 glutamate dehydrogenase 1 JBrowse link 16 10,661,486 10,695,557 RGD:1624291
RGD:1600115
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:2301557
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 12 17,309,122 17,315,267 RGD:1600115
RGD:1624291
G Gpr39 G protein-coupled receptor 39 JBrowse link 13 42,008,642 42,220,737 RGD:1624291
G Gpr68 G protein-coupled receptor 68 JBrowse link 6 124,874,151 124,903,949 RGD:1624291
G Irs2 insulin receptor substrate 2 JBrowse link 16 83,824,515 83,848,569 RGD:1624291
RGD:1600115
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:729103
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1641815
G Mcu mitochondrial calcium uniporter JBrowse link 20 29,037,452 29,199,224 RGD:1624291
RGD:1600115
G Myrip myosin VIIA and Rab interacting protein JBrowse link 8 128,972,307 129,139,257 RGD:8554303
G Nkx6-1 NK6 homeobox 1 JBrowse link 14 9,555,264 9,562,197 RGD:2306242
G Nlgn2 neuroligin 2 JBrowse link 10 56,431,586 56,444,847 RGD:9743981
RGD:1600115
RGD:1624291
RGD:2314456
G Nnat neuronatin JBrowse link 3 154,043,873 154,046,334 RGD:1624291
RGD:13792537
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 JBrowse link 5 151,776,004 151,779,319 RGD:2311606
G Oga O-GlcNAcase JBrowse link 1 265,506,752 265,542,452 RGD:2305956
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) JBrowse link 15 34,216,735 34,224,357 RGD:7242950
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:2306975
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 JBrowse link 13 47,413,453 47,440,682 RGD:2304071
G Pfkm phosphofructokinase, muscle JBrowse link 7 139,702,066 139,722,132 RGD:1624291
RGD:1600115
G Ppard peroxisome proliferator-activated receptor delta JBrowse link 20 7,818,289 7,883,482 RGD:2324877
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:1624291
G Psmd9 proteasome 26S subunit, non-ATPase 9 JBrowse link 12 38,786,539 38,805,121 RGD:633869
G Ptbp1 polypyrimidine tract binding protein 1 JBrowse link 7 12,663,965 12,673,723 RGD:10045958
G Rbp4 retinol binding protein 4 JBrowse link 1 256,806,476 256,813,678 RGD:1624291
RGD:1600115
G Rph3al rabphilin 3A-like (without C2 domains) JBrowse link 10 63,989,556 64,140,584 RGD:1600115
RGD:1624291
G Serp1 stress-associated endoplasmic reticulum protein 1 JBrowse link 2 148,718,279 148,722,263 RGD:1624291
RGD:1600115
G Sirt3 sirtuin 3 JBrowse link 1 213,613,502 213,636,061 RGD:9586042
G Slc30a8 solute carrier family 30 member 8 JBrowse link 7 91,832,988 91,869,329 RGD:2315022
G Snap25 synaptosome associated protein 25 JBrowse link 3 129,697,408 129,788,417 RGD:1581081
G Sox4 SRY-box transcription factor 4 JBrowse link 17 37,615,022 37,619,728 RGD:1624291
G Tardbp TAR DNA binding protein JBrowse link 5 165,432,089 165,442,232 RGD:7243008
G Tcf7l2 transcription factor 7 like 2 JBrowse link 1 276,686,911 276,730,517 RGD:1624291
RGD:13792537
G Tm7sf3 transmembrane 7 superfamily member 3 JBrowse link 4 180,913,703 180,951,564 RGD:1624291
RGD:1600115
G Trh thyrotropin releasing hormone JBrowse link 4 124,110,716 124,113,242 RGD:1600419
RGD:13792537
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 JBrowse link 20 11,434,062 11,482,880 RGD:9999436
G Ucn3 urocortin 3 JBrowse link 17 69,959,879 69,966,532 RGD:2306172
positive regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy8 adenylate cyclase 8 JBrowse link 7 105,353,883 105,593,372 RGD:1600115
RGD:1624291
RGD:8553299
G Ano1 anoctamin 1 JBrowse link 1 217,754,349 217,902,540 RGD:1624291
RGD:1600115
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
RGD:1600115
G Atg7 autophagy related 7 JBrowse link 4 146,570,113 146,777,093 RGD:1624291
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291
RGD:1600115
G Baiap3 BAI1-associated protein 3 JBrowse link 10 14,601,133 14,613,881 RGD:1624291
RGD:1600115
G C1qtnf12 C1q and TNF related 12 JBrowse link 5 173,390,901 173,395,276 RGD:1624291
RGD:1600115
G C2cd2l C2CD2-like JBrowse link 8 48,641,792 48,652,119 RGD:1624291
RGD:1600115
G Cacna1d calcium voltage-gated channel subunit alpha1 D JBrowse link 16 6,110,294 6,405,022 RGD:13506727
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:1600115
RGD:1624291
G Cltrn collectrin, amino acid transport regulator JBrowse link X 32,118,082 32,153,687 RGD:1624291
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:5508172
G Dynll1 dynein light chain LC8-type 1 JBrowse link 12 47,074,200 47,076,573 RGD:1642149
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:1600115
RGD:13792537
RGD:1624291
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:12905046
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:1624291
RGD:1600115
G Gpr27 G protein-coupled receptor 27 JBrowse link 4 132,137,793 132,138,926 RGD:1624291
RGD:1600115
G Gpr39 G protein-coupled receptor 39 JBrowse link 13 42,008,642 42,220,737 RGD:1624291
G Gpr68 G protein-coupled receptor 68 JBrowse link 6 124,874,151 124,903,949 RGD:1624291
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Kif5b kinesin family member 5B JBrowse link 17 54,181,416 54,219,048 RGD:11059539
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:10412039
G Lrp1 LDL receptor related protein 1 JBrowse link 7 70,846,313 70,927,028 RGD:13800516
G Mpc2 mitochondrial pyruvate carrier 2 JBrowse link 13 83,680,527 83,700,491 RGD:1624291
RGD:1600115
G Myh9 myosin, heavy chain 9 JBrowse link 7 118,740,005 118,792,507 RGD:12798521
G Nadk NAD kinase JBrowse link 5 172,984,930 173,015,505 RGD:13703105
G Ncoa6 nuclear receptor coactivator 6 JBrowse link 3 150,919,317 150,990,391 RGD:9590126
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1600115
RGD:1624291
G Oxct1 3-oxoacid CoA transferase 1 JBrowse link 2 53,859,738 54,007,733 RGD:2326185
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:1624291
RGD:1600115
G Phpt1 phosphohistidine phosphatase 1 JBrowse link 3 2,797,037 2,798,436 RGD:8554604
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:6482760
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:8553382
RGD:1624291
RGD:1600115
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:10413842
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:14392803
G Rfx6 regulatory factor X, 6 JBrowse link 20 32,709,282 32,764,040 RGD:1624291
RGD:1600115
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:9585658
G Sri sorcin JBrowse link 4 23,004,657 23,029,233 RGD:1624291
RGD:1600115
G Stx4 syntaxin 4 JBrowse link 1 199,287,384 199,295,606 RGD:1600115
RGD:1624291
G Sybu syntabulin JBrowse link 7 83,600,614 83,670,121 RGD:8554225
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 JBrowse link 5 3,783,247 3,836,485 RGD:10043784
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:10003029
G Vsnl1 visinin-like 1 JBrowse link 6 37,001,360 37,121,969 RGD:1624291
RGD:1600115
regulation of insulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arntl aryl hydrocarbon receptor nuclear translocator-like JBrowse link 1 178,039,002 178,137,469 RGD:1600115
RGD:1624291
G Cartpt CART prepropeptide JBrowse link 2 30,125,249 30,127,408 RGD:2313632
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:1624291
RGD:1600115
G Clock clock circadian regulator JBrowse link 14 34,418,226 34,502,218 RGD:1600115
RGD:1624291
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:2314628
G Cpt1a carnitine palmitoyltransferase 1A JBrowse link 1 218,568,157 218,629,679 RGD:1298597
G Ensa endosulfine alpha JBrowse link 2 197,752,544 197,759,882 RGD:1624291
RGD:1600115
G G6pc2 glucose-6-phosphatase catalytic subunit 2 JBrowse link 3 55,464,528 55,467,170 RGD:1624291
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:1624291
G Gck glucokinase JBrowse link 14 86,149,146 86,191,589 RGD:1624291
RGD:13792537
G Gip gastric inhibitory polypeptide JBrowse link 10 83,835,080 83,848,399 RGD:632885
G Hnf4a hepatocyte nuclear factor 4, alpha JBrowse link 3 159,902,441 159,965,003 RGD:1624291
RGD:1600115
G Ica1 islet cell autoantigen 1 JBrowse link 4 34,635,509 34,780,187 RGD:1600115
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1624291
RGD:1600115
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 JBrowse link 1 102,103,093 102,107,134 RGD:1624291
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:1624291
RGD:1600115
G LOC499235 LRRGT00141 JBrowse link 1 171,996,406 171,997,611 RGD:1600115
G Mtnr1b melatonin receptor 1B JBrowse link 8 14,359,270 14,373,894 RGD:1624291
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:1624291
RGD:1600115
G Pde3b phosphodiesterase 3B JBrowse link 1 183,892,841 184,078,071 RGD:1624291
G Per2 period circadian regulator 2 JBrowse link 9 98,555,154 98,597,362 RGD:1624291
RGD:1600115
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:8553382
G Rfx3 regulatory factor X3 JBrowse link 1 245,853,332 246,110,648 RGD:1624291
RGD:1600115
G Rfx6 regulatory factor X, 6 JBrowse link 20 32,709,282 32,764,040 RGD:1624291
RGD:13792537
G Slc16a1 solute carrier family 16 member 1 JBrowse link 2 207,108,552 207,129,352 RGD:1624291
RGD:1600115
G Slc8b1 solute carrier family 8 member B1 JBrowse link 12 41,566,980 41,590,294 RGD:1624291
RGD:1600115
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:1624291
G Sstr5 somatostatin receptor 5 JBrowse link 10 14,847,749 14,853,827 RGD:1624291
RGD:13792537
RGD:1600115
G Syt7 synaptotagmin 7 JBrowse link 1 226,435,816 226,498,008 RGD:2311143
RGD:1600115
RGD:1624291
G Syt7_v1 synaptotagmin 7, variant 1 RGD:2311143
G Syt9 synaptotagmin 9 JBrowse link 1 171,592,703 171,769,780 RGD:2311147
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 JBrowse link 1 219,126,687 219,139,466 RGD:1624291
RGD:1600115
G Tfap2b transcription factor AP-2 beta JBrowse link 9 25,410,669 25,440,568 RGD:1600115
RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Uqcc2 ubiquinol-cytochrome c reductase complex assembly factor 2 JBrowse link 20 5,712,200 5,723,902 RGD:1624291
RGD:1600115
regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy5 adenylate cyclase 5 JBrowse link 11 68,695,839 68,842,452 RGD:1600115
RGD:1624291
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:1624291
RGD:1600115
G Brsk2 BR serine/threonine kinase 2 JBrowse link 1 214,918,757 214,940,883 RGD:1624291
RGD:1600115
G Cacna1e calcium voltage-gated channel subunit alpha1 E JBrowse link 13 71,899,445 72,534,992 RGD:1624291
G Cdk16 cyclin-dependent kinase 16 JBrowse link X 1,707,285 1,718,821 RGD:1600115
RGD:1624291
G Ddrgk1 DDRGK domain containing 1 JBrowse link 3 123,195,580 123,206,828 RGD:11567254
G Efna5 ephrin A5 JBrowse link 9 110,054,002 110,329,878 RGD:1624291
RGD:1600115
G Epha5 EPH receptor A5 JBrowse link 14 25,589,312 25,958,258 RGD:1600115
RGD:1624291
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:1624291
G Hmgn3 high mobility group nucleosomal binding domain 3 JBrowse link 8 90,628,203 90,665,055 RGD:1624291
RGD:1600115
G LOC102554748 nidogen-2-like JBrowse link 7 380,313 427,615 RGD:13792537
G Lrp5 LDL receptor related protein 5 JBrowse link 1 218,816,833 218,920,147 RGD:1624291
RGD:13792537
G Mir130a microRNA 130a JBrowse link 3 72,141,037 72,141,124 RGD:1624291
G Mir200a microRNA 200a JBrowse link 5 173,489,366 173,489,454 RGD:1624291
G Mir410 microRNA 410 JBrowse link 6 133,893,997 133,894,072 RGD:1624291
G Myt1 myelin transcription factor 1 JBrowse link 3 177,281,365 177,341,550 RGD:1624291
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 JBrowse link 10 86,683,875 86,690,815 RGD:1600115
RGD:1624291
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1624291
G Nrxn1 neurexin 1 JBrowse link 6 13,886,757 15,191,660 RGD:1624291
G Piwil4 piwi-like RNA-mediated gene silencing 4 JBrowse link 8 13,208,774 13,251,970 RGD:13800537
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:1624291
G Sidt2 SID1 transmembrane family, member 2 JBrowse link 8 50,230,335 50,246,979 RGD:1624291
RGD:1600115
G Slc9b2 solute carrier family 9 member B2 JBrowse link 2 240,485,254 240,519,166 RGD:1624291
RGD:1600115
G Stxbp4 syntaxin binding protein 4 JBrowse link 10 78,005,745 78,168,641 RGD:1624291
RGD:1600115
G Sybu syntabulin JBrowse link 7 83,600,614 83,670,121 RGD:8554225
G Tcf7l2 transcription factor 7 like 2 JBrowse link 1 276,686,911 276,730,517 RGD:1624291
G Tiam1 TIAM Rac1 associated GEF 1 JBrowse link 11 29,931,083 30,061,173 RGD:10043296
G Ufm1 ubiquitin-fold modifier 1 JBrowse link 2 143,096,268 143,104,412 RGD:11567254

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    cellular process 16266
      export from cell 1174
        secretion by cell 1125
          protein secretion 634
            insulin secretion 231
              insulin secretion involved in cellular response to glucose stimulus + 95
              negative regulation of insulin secretion + 53
              positive regulation of insulin secretion + 93
              regulation of insulin secretion + 193
Path 2
Term Annotations click to browse term
  biological_process 18166
    localization 6061
      establishment of localization 4655
        transport 4517
          nitrogen compound transport 2185
            amide transport 1867
              peptide transport 1834
                peptide secretion 687
                  peptide hormone secretion 294
                    insulin secretion 231
                      insulin secretion involved in cellular response to glucose stimulus + 95
                      negative regulation of insulin secretion + 53
                      positive regulation of insulin secretion + 93
                      regulation of insulin secretion + 193
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.