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ONTOLOGY REPORT - ANNOTATIONS


Term:AP-type membrane coat adaptor complex
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Accession:GO:0030119 term browser browse the term
Definition:Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa).
Synonyms:related_synonym: clathrin adaptor


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AP-type membrane coat adaptor complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap2b1 adaptor related protein complex 2 subunit beta 1 JBrowse link 10 70,516,462 70,621,973 RGD:2306271
G Ap5b1 adaptor related protein complex 5 subunit beta 1 JBrowse link 1 220,948,318 220,952,349 RGD:1624291
RGD:13792537
RGD:1600115
G Ap5m1 adaptor related protein complex 5 subunit mu 1 JBrowse link 15 25,933,483 25,955,745 RGD:1624291
RGD:13792537
RGD:1600115
G Ap5s1 adaptor related protein complex 5 subunit sigma 1 JBrowse link 3 123,754,035 123,757,349 RGD:1624291
RGD:13792537
AP-1 adaptor complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aftph aftiphilin JBrowse link 14 104,921,633 104,975,763 RGD:1624291
RGD:13792537
G Ap1g2 adaptor related protein complex 1 subunit gamma 2 JBrowse link 15 33,759,108 33,767,017 RGD:1600115
G Clba1 clathrin binding box of aftiphilin containing 1 JBrowse link 6 137,386,694 137,393,490 RGD:13792537
G Slc18a3 solute carrier family 18 member A3 JBrowse link 16 8,682,668 8,685,529 RGD:2317430
RGD:13792537
AP-2 adaptor complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 JBrowse link 1 100,896,582 100,926,443 RGD:1624291
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 JBrowse link 1 214,534,217 214,607,497 RGD:12793054
RGD:1624291
RGD:1600115
G Ap2b1 adaptor related protein complex 2 subunit beta 1 JBrowse link 10 70,516,462 70,621,973 RGD:1624291
G Ap2m1 adaptor related protein complex 2 subunit mu 1 JBrowse link 11 84,041,184 84,047,542 RGD:12793054
RGD:1624291
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 JBrowse link 1 78,671,238 78,682,847 RGD:727584
RGD:2306270
RGD:1624291
G Btbd8 BTB domain containing 8 JBrowse link 14 3,282,422 3,351,740 RGD:13601995
RGD:1624291
RGD:1600115
G Eps15 epidermal growth factor receptor pathway substrate 15 JBrowse link 5 128,923,809 129,022,268 RGD:1624291
G Picalm phosphatidylinositol binding clathrin assembly protein JBrowse link 1 154,377,229 154,458,966 RGD:1624291
RGD:1600115
G Sgip1 SH3GL interacting endocytic adaptor 1 JBrowse link 5 122,300,415 122,498,478 RGD:1600115
RGD:8554282
RGD:1624291
G Slc18a3 solute carrier family 18 member A3 JBrowse link 16 8,682,668 8,685,529 RGD:2317430
RGD:13792537
G Tbc1d5 TBC1 domain family, member 5 JBrowse link 9 1,144,641 1,747,732 RGD:1624291
AP-3 adaptor complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap3b1 adaptor related protein complex 3 subunit beta 1 JBrowse link 2 24,022,815 24,227,522 RGD:1600115
G Ap3b2 adaptor related protein complex 3 subunit beta 2 JBrowse link 1 143,284,041 143,315,846 RGD:1600115
G Ap3d1 adaptor related protein complex 3 subunit delta 1 JBrowse link 7 11,838,639 11,873,992 RGD:13792537
G Ap3s1 adaptor related protein complex 3 subunit sigma 1 JBrowse link 18 40,732,472 40,798,064 RGD:1624291
G Ap3s2 adaptor related protein complex 3 subunit sigma 2 JBrowse link 1 141,612,961 141,655,417 RGD:1624291
G Vps11 VPS11 core subunit of CORVET and HOPS complexes JBrowse link 8 48,677,492 48,692,295 RGD:1624291
G Vps16 VPS16 core subunit of CORVET and HOPS complexes JBrowse link 3 122,947,887 122,969,543 RGD:1624291
G Vps18 VPS18 core subunit of CORVET and HOPS complexes JBrowse link 3 111,097,352 111,108,206 RGD:1624291
G Vps33a VPS33A core subunit of CORVET and HOPS complexes JBrowse link 12 38,459,816 38,482,903 RGD:1624291
G Vps39 VPS39 subunit of HOPS complex JBrowse link 3 112,087,213 112,125,307 RGD:1624291
G Vps41 VPS41 subunit of HOPS complex JBrowse link 17 48,643,754 48,810,633 RGD:10054072
RGD:1624291
AP-4 adaptor complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap4b1 adaptor related protein complex 4 subunit beta 1 JBrowse link 2 206,293,679 206,305,705 RGD:1624291
G Ap4e1 adaptor related protein complex 4 subunit epsilon 1 JBrowse link 3 119,484,714 119,548,491 RGD:1624291
G Ap4m1 adaptor related protein complex 4 subunit mu 1 JBrowse link 12 19,314,222 19,320,339 RGD:1600115
RGD:1624291
G Ap4s1 adaptor related protein complex 4 subunit sigma 1 JBrowse link 6 72,461,977 72,502,717 RGD:1624291
G Tepsin TEPSIN, adaptor related protein complex 4 accessory protein JBrowse link 10 109,271,161 109,278,745 RGD:11250428
RGD:1624291
AP-5 adaptor complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07035428.1 RGD:1600115
G AABR07035428.2 RGD:1600115
clathrin adaptor complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap1b1 adaptor related protein complex 1 subunit beta 1 JBrowse link 14 85,230,652 85,281,806 RGD:1600115
G Ap1m1 adaptor related protein complex 1 subunit mu 1 JBrowse link 16 19,288,354 19,303,818 RGD:1600115
G Ap1m2 adaptor related protein complex 1 subunit mu 2 JBrowse link 8 22,318,941 22,336,827 RGD:1600115
G Ap2b1 adaptor related protein complex 2 subunit beta 1 JBrowse link 10 70,516,462 70,621,973 RGD:1624291
G Ap2m1 adaptor related protein complex 2 subunit mu 1 JBrowse link 11 84,041,184 84,047,542 RGD:1600115
G Ap3b1 adaptor related protein complex 3 subunit beta 1 JBrowse link 2 24,022,815 24,227,522 RGD:1600115
G Ap3m1 adaptor related protein complex 3 subunit mu 1 JBrowse link 15 3,435,998 3,454,281 RGD:1600115
G Ap3m2 adaptor related protein complex 3 subunit mu 2 JBrowse link 16 74,075,842 74,091,230 RGD:1600115
G Ap4b1 adaptor related protein complex 4 subunit beta 1 JBrowse link 2 206,293,679 206,305,705 RGD:1600115
G Ap4m1 adaptor related protein complex 4 subunit mu 1 JBrowse link 12 19,314,222 19,320,339 RGD:1600115
G Lrrn3 leucine rich repeat neuronal 3 JBrowse link 6 61,374,328 61,405,195 RGD:727577

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19843
    protein-containing complex 5779
      membrane protein complex 1210
        AP-type membrane coat adaptor complex 41
          AP-3 adaptor complex 11
          AP-4 adaptor complex 5
          AP-5 adaptor complex 2
          clathrin adaptor complex + 23
Path 2
Term Annotations click to browse term
  cellular_component 19843
    cellular anatomical entity 19457
      membrane 9936
        membrane protein complex 1210
          membrane coat 95
            AP-type membrane coat adaptor complex 41
              AP-3 adaptor complex 11
              AP-4 adaptor complex 5
              AP-5 adaptor complex 2
              clathrin adaptor complex + 23
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.