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ONTOLOGY REPORT - ANNOTATIONS


Term:AP-1 adaptor complex
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Accession:GO:0030121 term browser browse the term
Definition:A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).
Synonyms:exact_synonym: HA1;   HA1 clathrin adaptor


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AP-1 adaptor complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aftph aftiphilin JBrowse link 14 104,921,633 104,975,763 RGD:1624291
RGD:13792537
G Ap1g2 adaptor related protein complex 1 subunit gamma 2 JBrowse link 15 33,759,108 33,767,017 RGD:13792537
G Clba1 clathrin binding box of aftiphilin containing 1 JBrowse link 6 137,386,694 137,393,490 RGD:13792537
G Slc18a3 solute carrier family 18 member A3 JBrowse link 16 8,682,668 8,685,529 RGD:2317430
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20118
    intracellular 14086
      cytoplasm 10966
        Golgi apparatus 1410
          clathrin coat of trans-Golgi network vesicle 10
            AP-1 adaptor complex 4
Path 2
Term Annotations click to browse term
  cellular_component 20118
    cellular anatomical entity 19774
      organelle 12827
        membrane-bounded organelle 11124
          vesicle 2025
            intracellular vesicle 1867
              cytoplasmic vesicle 1861
                coated vesicle 210
                  clathrin-coated vesicle 117
                    trans-Golgi network transport vesicle 30
                      trans-Golgi network transport vesicle membrane 12
                        clathrin coat of trans-Golgi network vesicle 10
                          AP-1 adaptor complex 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.