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ONTOLOGY REPORT - ANNOTATIONS


Term:AP-3 adaptor complex
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Accession:GO:0030123 term browser browse the term
Definition:A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).


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AP-3 adaptor complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap3b1 adaptor related protein complex 3 subunit beta 1 JBrowse link 2 24,022,815 24,227,522 RGD:1600115
G Ap3b2 adaptor related protein complex 3 subunit beta 2 JBrowse link 1 143,284,041 143,315,846 RGD:1600115
G Ap3d1 adaptor related protein complex 3 subunit delta 1 JBrowse link 7 11,838,639 11,873,992 RGD:13792537
G Ap3s1 adaptor related protein complex 3 subunit sigma 1 JBrowse link 18 40,732,472 40,798,064 RGD:1624291
G Ap3s2 adaptor related protein complex 3 subunit sigma 2 JBrowse link 1 141,612,961 141,655,417 RGD:1624291
G Vps11 VPS11 core subunit of CORVET and HOPS complexes JBrowse link 8 48,677,492 48,692,295 RGD:1624291
G Vps16 VPS16 core subunit of CORVET and HOPS complexes JBrowse link 3 122,947,887 122,969,543 RGD:1624291
G Vps18 VPS18 core subunit of CORVET and HOPS complexes JBrowse link 3 111,097,352 111,108,206 RGD:1624291
G Vps33a VPS33A core subunit of CORVET and HOPS complexes JBrowse link 12 38,459,816 38,482,903 RGD:1624291
G Vps39 VPS39 subunit of HOPS complex JBrowse link 3 112,087,213 112,125,307 RGD:1624291
G Vps41 VPS41 subunit of HOPS complex JBrowse link 17 48,643,754 48,810,633 RGD:10054072
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19951
    protein-containing complex 5828
      membrane protein complex 1228
        AP-type membrane coat adaptor complex 41
          AP-3 adaptor complex 11
Path 2
Term Annotations click to browse term
  cellular_component 19951
    cellular anatomical entity 19598
      membrane 9983
        membrane protein complex 1228
          membrane coat 101
            AP-type membrane coat adaptor complex 41
              AP-3 adaptor complex 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.