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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA-dependent DNA replication initiation
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Accession:GO:0030174 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
Synonyms:exact_synonym: DNA replication licencing;   DNA replication licensing
 broad_synonym: regulation of DNA replication initiation


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regulation of DNA-dependent DNA replication initiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdt1 chromatin licensing and DNA replication factor 1 JBrowse link 19 55,381,565 55,386,511 RGD:1624291
RGD:13792537
G Kat7 lysine acetyltransferase 7 JBrowse link 10 83,095,067 83,128,342 RGD:1624291
RGD:1600115
G Ticrr TOPBP1-interacting checkpoint and replication regulator JBrowse link 1 141,391,738 141,433,615 RGD:1624291
G Wdr18 WD repeat domain 18 JBrowse link 7 12,561,318 12,569,120 RGD:13792537
G Wrnip1 WRN helicase interacting protein 1 JBrowse link 17 32,933,395 32,953,641 RGD:1600115
RGD:1624291
positive regulation of DNA-dependent DNA replication initiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:1624291
RGD:1600115
G Ciz1 CDKN1A interacting zinc finger protein 1 JBrowse link 3 11,392,046 11,409,218 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      regulation of metabolic process 6582
        regulation of macromolecule metabolic process 6057
          regulation of DNA metabolic process 384
            regulation of DNA-dependent DNA replication initiation 7
              negative regulation of DNA-dependent DNA replication initiation + 0
              positive regulation of DNA-dependent DNA replication initiation + 2
              regulation of DNA replication initiation involved in plasmid copy number maintenance + 0
              regulation of initiation of premeiotic DNA replication + 0
              regulation of mitotic DNA replication initiation + 0
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      organic substance metabolic process 11030
        macromolecule metabolic process 9494
          macromolecule biosynthetic process 4956
            cellular macromolecule biosynthetic process 4823
              DNA replication 245
                DNA-dependent DNA replication 145
                  DNA replication initiation 27
                    regulation of DNA-dependent DNA replication initiation 7
                      negative regulation of DNA-dependent DNA replication initiation + 0
                      positive regulation of DNA-dependent DNA replication initiation + 2
                      regulation of DNA replication initiation involved in plasmid copy number maintenance + 0
                      regulation of initiation of premeiotic DNA replication + 0
                      regulation of mitotic DNA replication initiation + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.