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ONTOLOGY REPORT - ANNOTATIONS


Term:filopodium
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Accession:GO:0030175 term browser browse the term
Definition:Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
Comment:A filopodium may be approximately 0.1 um wide, 5-10 um long, and up to 50 um long in axon growth cones; contain a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473.
Synonyms:alt_id: GO:0030028
 xref: NIF_Subcellular:sao1046371754;   Wikipedia:Filopodia


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filopodium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acp3 acid phosphatase 3 JBrowse link 8 112,838,574 112,884,062 RGD:1600115
RGD:1624291
G Acta1 actin, alpha 1, skeletal muscle JBrowse link 19 56,674,072 56,677,084 RGD:1600115
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:1600115
G Actc1 actin, alpha, cardiac muscle 1 JBrowse link 3 105,507,403 105,512,939 RGD:1600115
G Actg2 actin gamma 2, smooth muscle JBrowse link 4 115,215,160 115,239,746 RGD:1600115
G Actn2 actinin alpha 2 JBrowse link 17 66,304,530 66,397,647 RGD:1624291
G Baiap2 BAR/IMD domain containing adaptor protein 2 JBrowse link 10 109,107,326 109,187,458 RGD:1600115
G Cd302 CD302 molecule JBrowse link 3 46,327,382 46,361,092 RGD:1624291
G Cdc42 cell division cycle 42 JBrowse link 5 155,690,267 155,728,385 RGD:1624291
G Cdk5 cyclin-dependent kinase 5 JBrowse link 4 7,282,945 7,287,427 RGD:1624291
G Cfl1 cofilin 1 JBrowse link 1 220,869,805 220,873,337 RGD:11570532
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:6904210
G Cxadr CXADR, Ig-like cell adhesion molecule JBrowse link 11 16,826,269 16,873,564 RGD:1624291
RGD:1600115
G Dag1 dystroglycan 1 JBrowse link 8 116,980,501 116,993,182 RGD:1624291
G Dbn1 drebrin 1 JBrowse link 17 9,679,511 9,693,878 RGD:10395284
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:1624291
G Dnali1 dynein, axonemal, light intermediate chain 1 JBrowse link 5 143,053,365 143,062,203 RGD:1624291
RGD:13792537
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 JBrowse link 6 134,958,854 135,085,769 RGD:1624291
RGD:1600115
G Enah ENAH, actin regulator JBrowse link 13 100,297,421 100,415,335 RGD:1624291
G Epha4 Eph receptor A4 JBrowse link 9 83,111,222 83,253,486 RGD:5688744
G Ermn ermin JBrowse link 3 44,080,350 44,086,006 RGD:1624291
G Ezr ezrin JBrowse link 1 47,287,872 47,331,412 RGD:7207797
RGD:1624291
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 JBrowse link 15 106,375,298 106,625,837 RGD:1600115
G Fat1 FAT atypical cadherin 1 JBrowse link 16 50,372,150 50,501,716 RGD:1624291
G Fgd4 FYVE, RhoGEF and PH domain containing 4 JBrowse link 11 88,699,222 88,796,677 RGD:1624291
RGD:1600115
G Fgf13 fibroblast growth factor 13 JBrowse link X 142,053,648 142,589,274 RGD:1624291
RGD:1600115
G Fscn1 fascin actin-bundling protein 1 JBrowse link 12 13,655,459 13,668,595 RGD:2317774
RGD:13792537
RGD:1624291
G Fscn3 fascin actin-bundling protein 3 JBrowse link 4 55,719,976 55,729,442 RGD:13792537
G Gpm6a glycoprotein m6a JBrowse link 16 39,367,697 39,719,292 RGD:8554337
RGD:13792537
G Igf2bp1 insulin-like growth factor 2 mRNA binding protein 1 JBrowse link 10 83,774,178 83,823,323 RGD:1600115
G Inppl1 inositol polyphosphate phosphatase-like 1 JBrowse link 1 166,898,177 166,912,524 RGD:1600115
G Iqgap2 IQ motif containing GTPase activating protein 2 JBrowse link 2 26,161,628 26,439,067 RGD:1624291
G Itga6 integrin subunit alpha 6 JBrowse link 3 58,442,904 58,515,124 RGD:1302259
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:1624291
RGD:1600115
G Kcnn3 potassium calcium-activated channel subfamily N member 3 JBrowse link 2 188,837,280 188,991,794 RGD:7175515
G Kitlg KIT ligand JBrowse link 7 42,269,784 42,351,054 RGD:1624291
RGD:1600115
G Lcp1 lymphocyte cytosolic protein 1 JBrowse link 15 57,170,566 57,277,811 RGD:1624291
G Lrrc7 leucine rich repeat containing 7 JBrowse link 2 264,910,594 265,300,860 RGD:2314403
G Msn moesin JBrowse link X 65,226,834 65,294,192 RGD:1600115
RGD:1624291
G Mtm1 myotubularin 1 JBrowse link 6 18,821,821 18,840,449 RGD:1600115
RGD:1624291
G Myo10 myosin X JBrowse link 2 77,868,398 78,072,443 RGD:1624291
G Myo1b myosin Ib JBrowse link 9 54,706,005 54,766,054 RGD:8554686
G Myo1g myosin IG JBrowse link 14 86,781,243 86,796,393 RGD:1624291
G Myo3a myosin IIIA JBrowse link 17 88,952,635 89,167,538 RGD:1624291
G Nf2 neurofibromin 2 JBrowse link 14 84,996,905 85,088,547 RGD:1624291
RGD:1600115
G Palld palladin, cytoskeletal associated protein JBrowse link 16 31,865,712 31,948,168 RGD:2325786
G Palm paralemmin JBrowse link 7 12,708,024 12,721,055 RGD:1624291
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:1624291
RGD:1600115
G Podxl podocalyxin-like JBrowse link 4 58,829,049 58,893,353 RGD:1624291
RGD:1600115
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A JBrowse link 4 29,976,485 30,247,371 RGD:1624291
RGD:10043779
RGD:10002752
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B JBrowse link 10 82,800,704 82,816,735 RGD:1624291
RGD:1600115
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 JBrowse link 4 49,941,046 50,140,764 RGD:9589123
G Rapgef3 Rap guanine nucleotide exchange factor 3 JBrowse link 7 139,232,263 139,254,668 RGD:10054076
RGD:1600115
RGD:1624291
G Rdx radixin JBrowse link 8 56,570,728 56,612,851 RGD:1624291
G Ripor2 RHO family interacting cell polarization regulator 2 JBrowse link 17 42,324,594 42,549,907 RGD:1624291
RGD:1600115
G Rufy3 RUN and FYVE domain containing 3 JBrowse link 14 21,058,575 21,144,775 RGD:8554472
G Scimp SLP adaptor and CSK interacting membrane protein JBrowse link 10 57,415,429 57,436,412 RGD:1600115
RGD:1624291
G Shtn1 shootin 1 JBrowse link 1 280,129,228 280,233,873 RGD:10054086
RGD:10054078
G Slc9a3r1 SLC9A3 regulator 1 JBrowse link 10 103,713,045 103,730,145 RGD:1600115
G Snap25 synaptosome associated protein 25 JBrowse link 3 129,697,408 129,788,417 RGD:1299445
G Spata13 spermatogenesis associated 13 JBrowse link 15 40,937,652 41,066,645 RGD:1624291
G Srcin1 SRC kinase signaling inhibitor 1 JBrowse link 10 85,460,059 85,517,671 RGD:1299445
G Tenm2 teneurin transmembrane protein 2 JBrowse link 10 20,846,091 21,791,771 RGD:1600115
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 12 47,698,915 47,737,902 RGD:8553293
G Tubb3 tubulin, beta 3 class III JBrowse link 19 56,220,759 56,229,813 RGD:1600115
RGD:1624291
G Twf1 twinfilin actin-binding protein 1 JBrowse link 7 135,838,647 135,850,542 RGD:1624291
G Twf2 twinfilin actin-binding protein 2 JBrowse link 8 114,897,011 114,909,531 RGD:1624291
G Unc5c unc-5 netrin receptor C JBrowse link 2 247,045,813 247,397,483 RGD:1600115
RGD:1624291
G Utrn utrophin JBrowse link 1 6,451,809 6,970,040 RGD:1624291
G Vamp7 vesicle-associated membrane protein 7 JBrowse link 12 18,996,566 19,033,714 RGD:8554110
G Vasp vasodilator-stimulated phosphoprotein JBrowse link 1 80,170,608 80,185,882 RGD:1624291
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:1624291
G Vil1 villin 1 JBrowse link 9 81,689,802 81,717,623 RGD:1624291
dendritic filopodium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dbn1 drebrin 1 JBrowse link 17 9,679,511 9,693,878 RGD:10398728
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:1601176
RGD:13792537
RGD:1624291
RGD:1300188
G Fxr1 FMR1 autosomal homolog 1 JBrowse link 2 120,529,716 120,570,356 RGD:13792537
G Fxr2 FMR1 autosomal homolog 2 JBrowse link 10 56,237,814 56,257,877 RGD:13792537
G Map2 microtubule-associated protein 2 JBrowse link 9 73,204,753 73,462,965 RGD:13514082
filopodium membrane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap5 A-kinase anchoring protein 5 JBrowse link 6 99,356,509 99,361,909 RGD:2313249
G Antxr1 ANTXR cell adhesion molecule 1 JBrowse link 4 118,946,267 119,131,202 RGD:1600115
RGD:1624291
G Arf6 ADP-ribosylation factor 6 JBrowse link 6 91,697,109 91,698,257 RGD:1624291
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:1624291
G Fzd9 frizzled class receptor 9 JBrowse link 12 24,473,981 24,476,295 RGD:1624291
G Gap43 growth associated protein 43 JBrowse link 11 58,624,198 58,717,916 RGD:1624291
G Itga3 integrin subunit alpha 3 JBrowse link 10 82,855,841 82,887,755 RGD:1624291
G Itgav integrin subunit alpha V JBrowse link 3 71,113,269 71,205,958 RGD:1624291
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:1624291
G Msn moesin JBrowse link X 65,226,834 65,294,192 RGD:727296
G Myo10 myosin X JBrowse link 2 77,868,398 78,072,443 RGD:1600115
G Palm paralemmin JBrowse link 7 12,708,024 12,721,055 RGD:1624291
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:1624291
RGD:1600115
G Syne2 spectrin repeat containing nuclear envelope protein 2 JBrowse link 6 98,884,269 99,153,551 RGD:1624291
G Tbc1d10c TBC1 domain family, member 10C JBrowse link 1 219,431,094 219,439,102 RGD:1624291
G Ttyh1 tweety family member 1 JBrowse link 1 73,734,614 73,753,157 RGD:1624291
G Utrn utrophin JBrowse link 1 6,451,809 6,970,040 RGD:1624291
filopodium tip term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abi1 abl-interactor 1 JBrowse link 17 89,951,662 90,033,334 RGD:1600115
RGD:1624291
G Abi2 abl-interactor 2 JBrowse link 9 67,234,612 67,284,504 RGD:1624291
G Abitram actin binding transcription modulator JBrowse link 5 73,552,952 73,560,240 RGD:1624291
RGD:13792537
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 JBrowse link 1 100,896,582 100,926,443 RGD:1624291
G Cib1 calcium and integrin binding 1 JBrowse link 1 142,014,962 142,020,461 RGD:1624291
RGD:1600115
G Cyfip1 cytoplasmic FMR1 interacting protein 1 JBrowse link 1 114,258,773 114,347,138 RGD:11557987
G Ephb1 Eph receptor B1 JBrowse link 8 110,376,954 110,813,193 RGD:1624291
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:1624291
RGD:1600115
G Fzd3 frizzled class receptor 3 JBrowse link 15 48,601,259 48,670,257 RGD:1624291
G Morn4 MORN repeat containing 4 JBrowse link 1 261,323,079 261,333,383 RGD:1624291
RGD:1600115
G Myo10 myosin X JBrowse link 2 77,868,398 78,072,443 RGD:1600115
G Myo3a myosin IIIA JBrowse link 17 88,952,635 89,167,538 RGD:1624291
G Myo3b myosin IIIB JBrowse link 3 56,355,433 56,717,740 RGD:1624291
G Myo5a myosin VA JBrowse link 8 82,038,966 82,156,507 RGD:1624291
RGD:1600115
G Myo9b myosin IXb JBrowse link 16 19,669,373 19,754,065 RGD:1624291
G Nlgn1 neuroligin 1 JBrowse link 2 111,057,291 111,973,681 RGD:8553605
G Ttyh1 tweety family member 1 JBrowse link 1 73,734,614 73,753,157 RGD:1624291
G Ube2k ubiquitin-conjugating enzyme E2K JBrowse link 14 44,289,247 44,348,691 RGD:1624291
G Vil1 villin 1 JBrowse link 9 81,689,802 81,717,623 RGD:1624291
growth cone filopodium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apbb1 amyloid beta precursor protein binding family B member 1 JBrowse link 1 170,387,625 170,411,263 RGD:10053998
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:10053998
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:1624291
RGD:1600115
G Itga3 integrin subunit alpha 3 JBrowse link 10 82,855,841 82,887,755 RGD:13593531

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19843
    cellular anatomical entity 19457
      cell projection 2468
        plasma membrane bounded cell projection 2408
          actin-based cell projection 229
            filopodium 104
              actin filament bundle of filopodium 0
              dendritic filopodium 5
              filopodium membrane 17
              filopodium tip 19
              growth cone filopodium 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.