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ONTOLOGY REPORT - ANNOTATIONS


Term:filopodium
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Accession:GO:0030175 term browser browse the term
Definition:Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
Comment:A filopodium may be approximately 0.1 um wide, 5-10 um long, and up to 50 um long in axon growth cones; contain a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473.
Synonyms:alt_id: GO:0030028
 xref: NIF_Subcellular:sao1046371754;   Wikipedia:Filopodia


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filopodium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acpp acid phosphatase, prostate JBrowse link 9 104,288,240 104,337,722 RGD:2290270
G Actn2 actinin alpha 2 JBrowse link 13 12,269,426 12,340,732 RGD:2290270
G Cd302 CD302 antigen JBrowse link 2 60,251,993 60,284,484 RGD:2290270
G Cdk5 cyclin-dependent kinase 5 JBrowse link 5 24,407,597 24,423,587 RGD:2290270
G Cfl1 cofilin 1, non-muscle JBrowse link 19 5,490,455 5,494,031 RGD:2290270
G Crp C-reactive protein, pentraxin-related JBrowse link 1 172,698,056 172,699,966 RGD:2290270
G Cxadr coxsackie virus and adenovirus receptor JBrowse link 16 78,301,226 78,359,785 RGD:2290270
G Dag1 dystroglycan 1 JBrowse link 9 108,204,861 108,263,977 RGD:2290270
G Dbn1 drebrin 1 JBrowse link 13 55,473,428 55,488,126 RGD:2290270
G Dmd dystrophin, muscular dystrophy JBrowse link X 82,814,664 85,205,050 RGD:2290270
G Dnali1 dynein, axonemal, light intermediate polypeptide 1 JBrowse link 4 125,055,339 125,065,657 RGD:2290270
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 JBrowse link 12 110,601,395 110,666,944 RGD:2290270
G Enah ENAH actin regulator JBrowse link 1 181,896,384 182,027,556 RGD:2290270
G Epha4 Eph receptor A4 JBrowse link 1 77,367,182 77,515,107 RGD:2290270
G Ermn ermin, ERM-like protein JBrowse link 2 58,045,115 58,052,864 RGD:2290270
G Ezr ezrin JBrowse link 17 6,738,131 6,782,780 RGD:2290270
G Fat1 FAT atypical cadherin 1 JBrowse link 8 44,933,100 45,052,257 RGD:2290270
G Fgd4 FYVE, RhoGEF and PH domain containing 4 JBrowse link 16 16,416,910 16,600,534 RGD:2290270
G Fgf13 fibroblast growth factor 13 JBrowse link X 59,062,139 59,585,572 RGD:2290270
G Fscn1 fascin actin-bundling protein 1 JBrowse link 5 142,960,355 142,973,189 RGD:2290270
G Fscn3 fascin actin-bundling protein 3 JBrowse link 6 28,427,870 28,438,622 RGD:2290270
G Gpm6a glycoprotein m6a JBrowse link 8 54,779,434 55,060,878 RGD:2290270
G Iqgap2 IQ motif containing GTPase activating protein 2 JBrowse link 13 95,627,177 95,892,280 RGD:2290270
G Itga6 integrin alpha 6 JBrowse link 2 71,786,886 71,858,427 RGD:2290270
G Itgb1 integrin beta 1 (fibronectin receptor beta) JBrowse link 8 128,685,654 128,733,579 RGD:2290270
G Kcnn3 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 JBrowse link 3 89,520,164 89,672,494 RGD:2290270
G Kitl kit ligand JBrowse link 10 100,015,615 100,100,416 RGD:2290270
G Lcp1 lymphocyte cytosolic protein 1 JBrowse link 14 75,131,105 75,230,842 RGD:2290270
G Lrrc7 leucine rich repeat containing 7 JBrowse link 3 158,067,186 158,561,983 RGD:2290270
G Msn moesin JBrowse link X 96,096,045 96,168,553 RGD:2290270
G Mtm1 X-linked myotubular myopathy gene 1 JBrowse link X 71,210,767 71,315,413 RGD:2290270
G Myo10 myosin X JBrowse link 15 25,622,550 25,813,673 RGD:2290270
G Myo1b myosin IB JBrowse link 1 51,749,758 51,916,063 RGD:2290270
G Myo1g myosin IG JBrowse link 11 6,506,548 6,520,960 RGD:2290270
G Myo3a myosin IIIA JBrowse link 2 22,227,503 22,618,252 RGD:2290270
G Nf2 neurofibromin 2 JBrowse link 11 4,757,639 4,849,544 RGD:2290270
G Npcd neuronal pentraxin chromo domain JBrowse link 15 79,786,351 79,834,333 RGD:2290270
G Palld palladin, cytoskeletal associated protein JBrowse link 8 61,511,431 61,902,707 RGD:2290270
G Palm paralemmin JBrowse link 10 79,793,572 79,820,915 RGD:2290270
G Pdpn podoplanin JBrowse link 4 143,267,409 143,299,564 RGD:2290270
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A JBrowse link 6 4,902,872 5,165,661 RGD:2290270
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B JBrowse link 11 94,991,212 95,006,898 RGD:2290270
G Ptprz1 protein tyrosine phosphatase, receptor type Z, polypeptide 1 JBrowse link 6 22,875,315 23,052,916 RGD:2290270
G Rapgef3 Rap guanine nucleotide exchange factor (GEF) 3 JBrowse link 15 97,744,770 97,768,419 RGD:2290270
G Rdx radixin JBrowse link 9 52,047,150 52,088,738 RGD:2290270
G Ripor2 RHO family interacting cell polarization regulator 2 JBrowse link 13 24,501,524 24,733,806 RGD:2290270
G Rufy3 RUN and FYVE domain containing 3 JBrowse link 5 88,564,505 88,651,417 RGD:2290270
G Scimp SLP adaptor and CSK interacting membrane protein JBrowse link 11 70,790,932 70,812,561 RGD:2290270
G Shtn1 shootin 1 JBrowse link 19 58,973,358 59,076,124 RGD:2290270
G Snap25 synaptosomal-associated protein 25 JBrowse link 2 136,713,439 136,782,428 RGD:2290270
G Spata13 spermatogenesis associated 13 JBrowse link 14 60,485,168 60,764,556 RGD:2290270
G Srcin1 SRC kinase signaling inhibitor 1 JBrowse link 11 97,509,340 97,575,246 RGD:2290270
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 5 114,622,152 114,658,435 RGD:2290270
G Tubb3 tubulin, beta 3 class III JBrowse link 8 123,411,553 123,422,015 RGD:2290270
G Twf1 twinfilin actin binding protein 1 JBrowse link 15 94,577,948 94,589,884 RGD:2290270
G Twf2 twinfilin actin binding protein 2 JBrowse link 9 106,203,108 106,215,387 RGD:2290270
G Unc5c unc-5 netrin receptor C JBrowse link 3 141,465,564 141,834,924 RGD:2290270
G Utrn utrophin JBrowse link 10 12,382,187 12,869,888 RGD:2290270
G Vamp7 vesicle-associated membrane protein 7 RGD:2290270
G Vasp vasodilator-stimulated phosphoprotein JBrowse link 7 19,256,929 19,271,854 RGD:2290270
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 3 116,110,020 116,129,688 RGD:2290270
G Vil1 villin 1 JBrowse link 1 74,409,384 74,435,560 RGD:2290270
dendritic filopodium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dbn1 drebrin 1 JBrowse link 13 55,473,428 55,488,126 RGD:2290270
G Fmr1 FMRP translational regulator 1 JBrowse link X 68,678,536 68,717,963 RGD:2290270
G Fxr1 fragile X mental retardation gene 1, autosomal homolog JBrowse link 3 34,020,058 34,069,980 RGD:2290270
G Fxr2 fragile X mental retardation, autosomal homolog 2 JBrowse link 11 69,632,971 69,653,297 RGD:2290270
G Map2 microtubule-associated protein 2 JBrowse link 1 66,175,202 66,442,583 RGD:2290270
filopodium membrane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap5 A kinase (PRKA) anchor protein 5 JBrowse link 12 76,324,617 76,334,517 RGD:2290270
G Antxr1 anthrax toxin receptor 1 JBrowse link 6 87,133,853 87,335,809 RGD:2290270
G Arf6 ADP-ribosylation factor 6 JBrowse link 12 69,372,150 69,375,980 RGD:2290270
G Dmd dystrophin, muscular dystrophy JBrowse link X 82,814,664 85,205,050 RGD:2290270
G Fzd9 frizzled class receptor 9 JBrowse link 5 135,248,938 135,251,047 RGD:2290270
G Gap43 growth associated protein 43 JBrowse link 16 42,248,552 42,340,651 RGD:2290270
G Itga3 integrin alpha 3 JBrowse link 11 95,044,475 95,076,844 RGD:2290270
G Itgav integrin alpha V JBrowse link 2 83,722,303 83,806,917 RGD:2290270
G Itgb3 integrin beta 3 JBrowse link 11 104,608,000 104,670,476 RGD:2290270
G Msn moesin JBrowse link X 96,096,045 96,168,553 RGD:2290270
G Palm paralemmin JBrowse link 10 79,793,572 79,820,915 RGD:2290270
G Pdpn podoplanin JBrowse link 4 143,267,409 143,299,564 RGD:2290270
G Syne2 spectrin repeat containing, nuclear envelope 2 JBrowse link 12 75,818,318 76,110,928 RGD:2290270
G Tbc1d10c TBC1 domain family, member 10c JBrowse link 19 4,184,357 4,191,195 RGD:2290270
G Ttyh1 tweety family member 1 JBrowse link 7 4,119,530 4,135,407 RGD:2290270
G Utrn utrophin JBrowse link 10 12,382,187 12,869,888 RGD:2290270
filopodium tip term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abi1 abl-interactor 1 JBrowse link 2 22,940,073 23,040,241 RGD:2290270
G Abi2 abl-interactor 2 JBrowse link 1 60,405,768 60,481,945 RGD:2290270
G Abitram actin binding transcription modulator JBrowse link 4 56,802,329 56,809,605 RGD:2290270
G Ap2a1 adaptor-related protein complex 2, alpha 1 subunit JBrowse link 7 44,900,373 44,929,490 RGD:2290270
G Cib1 calcium and integrin binding 1 (calmyrin) JBrowse link 7 80,227,156 80,232,805 RGD:2290270
G Cyfip1 cytoplasmic FMR1 interacting protein 1 JBrowse link 7 55,842,022 55,932,633 RGD:2290270
G Ephb1 Eph receptor B1 JBrowse link 9 101,922,128 102,354,693 RGD:2290270
G Fmr1 FMRP translational regulator 1 JBrowse link X 68,678,536 68,717,963 RGD:2290270
G Fzd3 frizzled class receptor 3 JBrowse link 14 65,192,441 65,262,463 RGD:2290270
G Morn4 MORN repeat containing 4 JBrowse link 19 42,074,939 42,086,376 RGD:2290270
G Myo3a myosin IIIA JBrowse link 2 22,227,503 22,618,252 RGD:2290270
G Myo3b myosin IIIB JBrowse link 2 70,039,126 70,429,195 RGD:2290270
G Myo5a myosin VA JBrowse link 9 75,069,799 75,223,688 RGD:2290270
G Myo9b myosin IXb JBrowse link 8 71,272,576 71,360,713 RGD:2290270
G Nlgn1 neuroligin 1 JBrowse link 3 25,421,808 26,332,866 RGD:2290270
G Ttyh1 tweety family member 1 JBrowse link 7 4,119,530 4,135,407 RGD:2290270
G Ube2k ubiquitin-conjugating enzyme E2K JBrowse link 5 65,537,245 65,598,989 RGD:2290270
G Vil1 villin 1 JBrowse link 1 74,409,384 74,435,560 RGD:2290270
growth cone filopodium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apbb1 amyloid beta (A4) precursor protein-binding, family B, member 1 JBrowse link 7 105,558,465 105,581,924 RGD:2290270
G App amyloid beta (A4) precursor protein JBrowse link 16 84,952,666 85,175,255 RGD:2290270
G Fmr1 FMRP translational regulator 1 JBrowse link X 68,678,536 68,717,963 RGD:2290270
G Itga3 integrin alpha 3 JBrowse link 11 95,044,475 95,076,844 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 23058
    cellular anatomical entity 18625
      cell projection 2517
        plasma membrane bounded cell projection 2298
          actin-based cell projection 216
            filopodium 93
              actin filament bundle of filopodium 0
              dendritic filopodium 5
              filopodium membrane 16
              filopodium tip 18
              growth cone filopodium 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.