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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of Wnt signaling pathway
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Accession:GO:0030177 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
Synonyms:exact_synonym: positive regulation of Wnt receptor signaling pathway;   positive regulation of Wnt receptor signalling pathway;   positive regulation of Wnt-activated signaling pathway;   positive regulation of frizzled signaling pathway;   positive regulation of frizzled signalling pathway;   up regulation of Wnt receptor signaling pathway;   up regulation of frizzled signaling pathway;   upregulation of Wnt receptor signaling pathway;   upregulation of frizzled signaling pathway
 narrow_synonym: activation of Wnt receptor signaling pathway;   activation of frizzled signaling pathway;   stimulation of Wnt receptor signaling pathway;   stimulation of frizzled signaling pathway
 alt_id: GO:0045811


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positive regulation of Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp6ap2 ATPase H+ transporting accessory protein 2 JBrowse link X 11,137,889 11,164,854 RGD:1624291
RGD:13792537
G Atp6v0c ATPase H+ transporting V0 subunit C JBrowse link 10 13,537,031 13,543,407 RGD:1624291
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 JBrowse link 6 42,585,452 42,632,289 RGD:1600115
RGD:1624291
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
G Ccn4 cellular communication network factor 4 JBrowse link 7 107,695,227 107,723,759 RGD:1600115
RGD:1624291
G Cdc73 cell division cycle 73 JBrowse link 13 60,403,771 60,496,511 RGD:1624291
RGD:1600115
G Csnk1d casein kinase 1, delta JBrowse link 10 110,147,786 110,182,413 RGD:1624291
G Csnk1e casein kinase 1, epsilon JBrowse link 7 120,651,976 120,675,559 RGD:1624291
G Csnk2a1 casein kinase 2 alpha 1 JBrowse link 3 147,713,808 147,760,375 RGD:1624291
RGD:1600115
G Dact1 dishevelled-binding antagonist of beta-catenin 1 JBrowse link 6 93,740,440 93,751,003 RGD:1624291
G Depdc1b DEP domain containing 1B JBrowse link 2 39,980,796 40,069,982 RGD:1624291
RGD:13792537
G Disc1 DISC1 scaffold protein JBrowse link 19 57,818,838 58,069,992 RGD:1624291
G Dixdc1 DIX domain containing 1 JBrowse link 8 55,091,232 55,164,636 RGD:1624291
RGD:1600115
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:1624291
G Kank1 KN motif and ankyrin repeat domains 1 JBrowse link 1 243,201,073 243,398,531 RGD:1624291
G Lgr6 leucine-rich repeat-containing G protein-coupled receptor 6 JBrowse link 13 51,811,904 51,931,193 RGD:1624291
G Macf1 microtubule-actin crosslinking factor 1 JBrowse link 5 141,039,455 141,363,524 RGD:8553932
RGD:1624291
G Mbd2 methyl-CpG binding domain protein 2 JBrowse link 18 65,814,026 65,885,115 RGD:1624291
G NEWGENE_1306210 spindlin 1 JBrowse link 17 14,078,821 14,103,338 RGD:1600115
G Rspo1 R-spondin 1 JBrowse link 5 142,986,526 143,007,847 RGD:1624291
G Rspo2 R-spondin 2 JBrowse link 7 81,919,911 82,059,659 RGD:1624291
G Rspo3 R-spondin 3 JBrowse link 1 30,681,648 30,768,038 RGD:1624291
G Rspo4 R-spondin 4 JBrowse link 3 147,358,690 147,391,719 RGD:1624291
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 JBrowse link 8 22,648,323 22,739,468 RGD:1624291
RGD:1600115
G Spin1 spindlin 1 JBrowse link 16 884,854 930,527 RGD:1600115
RGD:1624291
G Sulf1 sulfatase 1 JBrowse link 5 5,999,520 6,186,901 RGD:1624291
RGD:13792537
RGD:1600115
G Sulf2 sulfatase 2 JBrowse link 3 162,791,349 162,872,984 RGD:1624291
RGD:13792537
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:1624291
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:13792537
G Wls Wnt ligand secretion mediator JBrowse link 2 266,315,036 266,431,220 RGD:10402040
RGD:1624291
G Wnt3 Wnt family member 3 JBrowse link 10 91,830,709 91,874,907 RGD:1624291
G Zeb2 zinc finger E-box binding homeobox 2 JBrowse link 3 29,857,289 29,985,932 RGD:1624291
G Zranb1 zinc finger RANBP2-type containing 1 JBrowse link 1 204,938,444 205,000,163 RGD:1624291
RGD:13792537
positive regulation of canonical Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adgra2 adhesion G protein-coupled receptor A2 JBrowse link 16 69,094,587 69,133,015 RGD:1624291
G Amer1 APC membrane recruitment protein 1 JBrowse link X 64,686,620 64,702,504 RGD:1624291
G Arntl aryl hydrocarbon receptor nuclear translocator-like JBrowse link 1 178,039,002 178,137,469 RGD:1600115
RGD:1624291
G Aspm assembly factor for spindle microtubules JBrowse link 13 56,546,021 56,591,793 RGD:1624291
G Bambi BMP and activin membrane-bound inhibitor JBrowse link 17 56,905,419 56,909,675 RGD:1624291
G Caprin2 caprin family member 2 JBrowse link 4 183,304,993 183,374,195 RGD:1624291
RGD:1600115
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Ccar2 cell cycle and apoptosis regulator 2 JBrowse link 15 51,818,887 51,834,443 RGD:1624291
G Cdh3 cadherin 3 JBrowse link 19 38,668,957 38,719,801 RGD:1624291
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:1624291
G Csnk1d casein kinase 1, delta JBrowse link 10 110,147,786 110,182,413 RGD:1624291
RGD:13792537
G Csnk1e casein kinase 1, epsilon JBrowse link 7 120,651,976 120,675,559 RGD:1624291
G Csnk1g1 casein kinase 1, gamma 1 JBrowse link 8 71,533,372 71,688,483 RGD:13792537
G Csnk1g2 casein kinase 1, gamma 2 JBrowse link 7 11,944,957 11,963,268 RGD:13792537
G Csnk1g3 casein kinase 1, gamma 3 JBrowse link 18 48,831,209 48,913,341 RGD:13792537
G Ctdnep1 CTD nuclear envelope phosphatase 1 JBrowse link 10 56,590,822 56,600,235 RGD:1624291
G Daam2 dishevelled associated activator of morphogenesis 2 JBrowse link 9 13,444,883 13,493,154 RGD:1624291
RGD:13792537
G Dact1 dishevelled-binding antagonist of beta-catenin 1 JBrowse link 6 93,740,440 93,751,003 RGD:1624291
G Dapk3 death-associated protein kinase 3 JBrowse link 7 11,392,436 11,400,855 RGD:1624291
G Ddx3x DEAD-box helicase 3, X-linked JBrowse link X 10,400,363 10,414,010 RGD:1624291
G Disc1 DISC1 scaffold protein JBrowse link 19 57,818,838 58,069,992 RGD:1624291
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 JBrowse link 2 237,148,918 237,240,883 RGD:1624291
G Dlx5 distal-less homeobox 5 JBrowse link 4 32,387,741 32,392,085 RGD:1624291
RGD:1600115
G Eda ectodysplasin-A JBrowse link X 69,730,123 70,222,693 RGD:1624291
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:1624291
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:1624291
G Fam53b family with sequence similarity 53, member B JBrowse link 1 204,714,468 204,805,738 RGD:1624291
RGD:13792537
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:1624291
G Fgf9 fibroblast growth factor 9 JBrowse link 15 38,341,657 38,386,945 RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:1624291
G Frat1 FRAT regulator of WNT signaling pathway 1 JBrowse link 1 261,071,965 261,075,244 RGD:1624291
G Fzd9 frizzled class receptor 9 JBrowse link 12 24,473,981 24,476,295 RGD:1624291
RGD:1600115
G Gid8 GID complex subunit 8 homolog JBrowse link 3 176,217,128 176,223,645 RGD:1624291
G Gpc3 glypican 3 JBrowse link X 139,579,268 139,947,093 RGD:1600115
RGD:13792537
RGD:1624291
G Gprc5b G protein-coupled receptor, class C, group 5, member B JBrowse link 1 188,688,743 188,713,724 RGD:1624291
G Gskip GSK3B interacting protein JBrowse link 6 129,512,950 129,536,320 RGD:1600115
RGD:1624291
G Ilk integrin-linked kinase JBrowse link 1 170,578,941 170,585,192 RGD:1624291
G Jrk Jrk helix-turn-helix protein JBrowse link 7 115,941,788 115,946,471 RGD:1624291
G Kank1 KN motif and ankyrin repeat domains 1 JBrowse link 1 243,201,073 243,398,531 RGD:1624291
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 JBrowse link 3 101,051,960 101,152,119 RGD:1624291
RGD:1600115
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 JBrowse link 7 58,447,097 58,587,787 RGD:1624291
RGD:1600115
G Lrrk1 leucine-rich repeat kinase 1 JBrowse link 1 127,166,866 127,301,053 RGD:1624291
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
G Lypd6 LY6/PLAUR domain containing 6 JBrowse link 3 35,566,956 35,707,416 RGD:13792537
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:1600115
RGD:1624291
G Nle1 notchless homolog 1 JBrowse link 10 70,250,959 70,261,880 RGD:1624291
G Nrarp Notch-regulated ankyrin repeat protein JBrowse link 3 2,396,143 2,398,697 RGD:1624291
RGD:13792537
G Peg12 paternally expressed 12 JBrowse link 1 123,097,861 123,100,464 RGD:13792537
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 JBrowse link 8 21,669,236 21,680,615 RGD:1624291
G Plekha4 pleckstrin homology domain containing A4 JBrowse link 1 101,517,702 101,540,802 RGD:1624291
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:1624291
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A JBrowse link 6 94,433,658 94,484,979 RGD:1624291
RGD:13792537
RGD:1600115
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B JBrowse link 6 8,219,385 8,280,127 RGD:13792537
G Ppm1n protein phosphatase, Mg2+/Mn2+ dependent 1N JBrowse link 1 80,190,293 80,193,002 RGD:13792537
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha JBrowse link 8 109,481,352 109,621,462 RGD:1624291
G Prdm15 PR/SET domain 15 JBrowse link 11 38,294,040 38,354,648 RGD:1624291
G Ptk7 protein tyrosine kinase 7 JBrowse link 9 16,662,588 16,729,888 RGD:1624291
G Reck reversion-inducing-cysteine-rich protein with kazal motifs JBrowse link 5 59,348,568 59,415,169 RGD:1624291
G Rnf146 ring finger protein 146 JBrowse link 1 30,856,923 30,873,814 RGD:1600115
RGD:1624291
G Rnf220 ring finger protein 220 JBrowse link 5 136,129,457 136,351,752 RGD:1624291
RGD:1600115
G Ror2 receptor tyrosine kinase-like orphan receptor 2 JBrowse link 17 11,953,552 12,134,386 RGD:1624291
G Rspo1 R-spondin 1 JBrowse link 5 142,986,526 143,007,847 RGD:1624291
G Rspo2 R-spondin 2 JBrowse link 7 81,919,911 82,059,659 RGD:1624291
G Rspo3 R-spondin 3 JBrowse link 1 30,681,648 30,768,038 RGD:1624291
G Ruvbl1 RuvB-like AAA ATPase 1 JBrowse link 4 120,411,917 120,447,458 RGD:1624291
G Scel sciellin JBrowse link 15 87,689,190 87,820,731 RGD:1624291
G Sema5a semaphorin 5A JBrowse link 2 85,377,318 85,808,970 RGD:1624291
RGD:1600115
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:10448946
RGD:1624291
G Sfrp4 secreted frizzled-related protein 4 JBrowse link 17 47,383,983 47,394,065 RGD:1624291
RGD:1600115
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:11079190
G Sox4 SRY-box transcription factor 4 JBrowse link 17 37,615,022 37,619,728 RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
G Sulf2 sulfatase 2 JBrowse link 3 162,791,349 162,872,984 RGD:1624291
G Tbl1x transducin (beta)-like 1 X-linked JBrowse link X 44,959,883 44,988,551 RGD:1624291
G Tbl1xr1 TBL1X receptor 1 JBrowse link 2 107,221,913 107,359,229 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Tmem198 transmembrane protein 198 JBrowse link 9 82,673,959 82,680,151 RGD:1624291
RGD:13792537
G Tmem198b transmembrane protein 198b JBrowse link 7 3,224,831 3,230,129 RGD:13792537
G Tnks tankyrase JBrowse link 16 60,925,093 61,067,192 RGD:1624291
RGD:13792537
G Tnks2 tankyrase 2 RGD:1624291
RGD:13792537
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:1600115
RGD:1624291
G Ube2b ubiquitin-conjugating enzyme E2B JBrowse link 10 37,439,947 37,454,867 RGD:1624291
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 JBrowse link 7
7
76,789,110
76,839,661
76,835,517
76,907,441
RGD:1600115
RGD:1624291
G Usp34 ubiquitin specific peptidase 34 JBrowse link 14 108,060,653 108,264,706 RGD:1624291
G Usp47 ubiquitin specific peptidase 47 JBrowse link 1 176,854,589 176,937,763 RGD:1624291
G Usp8 ubiquitin specific peptidase 8 JBrowse link 3 119,173,818 119,222,499 RGD:1624291
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:1624291
G Vps35 VPS35 retromer complex component JBrowse link 19 27,464,937 27,500,636 RGD:1624291
G Wls Wnt ligand secretion mediator JBrowse link 2 266,315,036 266,431,220 RGD:1624291
G Wnk1 WNK lysine deficient protein kinase 1 JBrowse link 4 152,452,211 152,578,469 RGD:1624291
G Wnk2 WNK lysine deficient protein kinase 2 JBrowse link 17 15,923,508 16,032,271 RGD:1624291
G Wnt10b Wnt family member 10B JBrowse link 7 140,448,284 140,466,159 RGD:1624291
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:1624291
RGD:1600115
RGD:13792537
G Yap1 Yes1 associated transcriptional regulator JBrowse link 8 6,133,014 6,204,240 RGD:1624291
G Zbed3 zinc finger, BED-type containing 3 JBrowse link 2 25,039,506 25,052,129 RGD:1624291
RGD:13792537
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
positive regulation of non-canonical Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csnk1d casein kinase 1, delta JBrowse link 10 110,147,786 110,182,413 RGD:1624291
G Csnk1e casein kinase 1, epsilon JBrowse link 7 120,651,976 120,675,559 RGD:10448953
RGD:1624291
G Rspo1 R-spondin 1 JBrowse link 5 142,986,526 143,007,847 RGD:1624291
G Rspo3 R-spondin 3 JBrowse link 1 30,681,648 30,768,038 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
positive regulation of non-canonical Wnt signaling pathway via JNK cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nkd1 NKD inhibitor of WNT signaling pathway 1 JBrowse link 19 19,434,720 19,509,087 RGD:1624291
positive regulation of Wnt signaling pathway by BMP signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
positive regulation of Wnt signaling pathway, planar cell polarity pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:1624291
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase JBrowse link 13 74,154,533 74,333,244 RGD:1624291
G Ankrd6 ankyrin repeat domain 6 JBrowse link 5 48,052,610 48,167,568 RGD:1624291
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:1624291
RGD:1600115
G Gpc3 glypican 3 JBrowse link X 139,579,268 139,947,093 RGD:8554067
RGD:1600115
RGD:1624291
G Mllt3 MLLT3, super elongation complex subunit JBrowse link 5 106,103,498 106,202,559 RGD:1624291
G Nkd1 NKD inhibitor of WNT signaling pathway 1 JBrowse link 19 19,434,720 19,509,087 RGD:1624291
G Plekha4 pleckstrin homology domain containing A4 JBrowse link 1 101,517,702 101,540,802 RGD:1624291
positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csnk1e casein kinase 1, epsilon JBrowse link 7 120,651,976 120,675,559 RGD:10448953

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    signaling 7456
      signal transduction 6872
        positive regulation of signal transduction 1635
          positive regulation of Wnt signaling pathway 133
            Wnt receptor recycling 0
            positive regulation of Wnt signaling pathway by BMP signaling pathway 1
            positive regulation of Wnt signaling pathway by Wnt receptor internalization 0
            positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region 0
            positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification 0
            positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation 1
            positive regulation of canonical Wnt signaling pathway + 100
            positive regulation of non-canonical Wnt signaling pathway + 14
Path 2
Term Annotations click to browse term
  biological_process 19336
    biological regulation 13340
      regulation of biological process 12655
        regulation of cellular process 11995
          signal transduction 6872
            cell surface receptor signaling pathway 2674
              cell surface receptor signaling pathway involved in cell-cell signaling 553
                Wnt signaling pathway 430
                  regulation of Wnt signaling pathway 307
                    positive regulation of Wnt signaling pathway 133
                      Wnt receptor recycling 0
                      positive regulation of Wnt signaling pathway by BMP signaling pathway 1
                      positive regulation of Wnt signaling pathway by Wnt receptor internalization 0
                      positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region 0
                      positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification 0
                      positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation 1
                      positive regulation of canonical Wnt signaling pathway + 100
                      positive regulation of non-canonical Wnt signaling pathway + 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.