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ONTOLOGY REPORT - ANNOTATIONS


Term:B cell differentiation
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Accession:GO:0030183 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: B lymphocyte differentiation
 related_synonym: B cell development
 alt_id: GO:0042115


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B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 ISO (MGI:MGI:3828349|PMID:17371977) BHF-UCL PMID:17371977 MGI:MGI:3828349 NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054
JBrowse link
G ADGRG3 adhesion G protein-coupled receptor G3 ISO (MGI:MGI:5645196|PMID:24113187) UniProtKB PMID:24113187 MGI:MGI:5645196 NCBI chr16:37,945,248...37,966,293
Ensembl chr16:57,077,429...57,098,456
JBrowse link
G BCL11A BAF chromatin remodeling complex subunit BCL11A ISO (MGI:MGI:2662805|PMID:12717432) MGI PMID:12717432 MGI:MGI:2662805 NCBI chr2A:60,552,908...60,655,437
Ensembl chr2A:61,695,613...61,795,800
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO (MGI:MGI:2156164|PMID:8170972), (MGI:MGI:85476|PMID:9028316) MGI PMID:8170972, PMID:9028316 MGI:MGI:2156164, MGI:MGI:85476 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BCL6 BCL6 transcription repressor ISO (MGI:MGI:3028360|PMID:14647274) MGI PMID:14647274 MGI:MGI:3028360 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124
JBrowse link
G CARD11 caspase recruitment domain family member 11 ISO (MGI:MGI:2664641|PMID:12818158) MGI PMID:12818158 MGI:MGI:2664641 NCBI chr 7:3,166,788...3,304,729
Ensembl chr 7:3,258,736...3,332,999
JBrowse link
G CD40LG CD40 ligand ISO (MGI:MGI:3028360|PMID:14647274) MGI PMID:14647274 MGI:MGI:3028360 NCBI chr  X:125,776,138...125,788,820
Ensembl chr  X:136,042,849...136,058,202
JBrowse link
G CD79A CD79a molecule ISO (MGI:MGI:2149180|PMID:11514602), (MGI:MGI:2687348|PMID:12097390) UniProtKB PMID:11514602, PMID:12097390 MGI:MGI:2149180, MGI:MGI:2687348 NCBI chr19:38,765,067...38,769,556
Ensembl chr19:47,270,377...47,274,711
JBrowse link
G CDH17 cadherin 17 ISO (MGI:MGI:3531365|PMID:15688343) UniProtKB PMID:15688343 MGI:MGI:3531365 NCBI chr 8:90,750,904...90,818,629
Ensembl chr 8:92,696,182...92,760,732
JBrowse link
G CEBPG CCAAT enhancer binding protein gamma ISO (PMID:1431100) UniProtKB PMID:1431100 NCBI chr19:30,295,603...30,304,984
Ensembl chr19:39,046,219...39,046,671
JBrowse link
G CLCF1 cardiotrophin like cytokine factor 1 ISO (MGI:MGI:1346205|PMID:10500198) MGI PMID:10500198 MGI:MGI:1346205 NCBI chr11:62,722,611...62,734,279 JBrowse link
G CR2 complement C3d receptor 2 ISO (PMID:2995485) UniProtKB PMID:2995485 NCBI chr 1:183,052,798...183,088,385
Ensembl chr 1:187,330,483...187,366,069
JBrowse link
G DCAF1 DDB1 and CUL4 associated factor 1 ISO (MGI:MGI:5314150|PMID:22157821) UniProtKB PMID:22157821 MGI:MGI:5314150 NCBI chr 3:51,326,589...51,430,217
Ensembl chr 3:52,560,427...52,663,807
JBrowse link
G DCLRE1C DNA cross-link repair 1C ISO (MGI:MGI:2447929|PMID:12504013) MGI PMID:12504013 MGI:MGI:2447929 NCBI chr10:14,901,335...14,956,947
Ensembl chr10:15,236,558...15,269,043
JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 ISO (MGI:MGI:5644772|PMID:25222125) UniProtKB PMID:25222125 MGI:MGI:5644772 NCBI chr 7:100,555,527...100,560,052
Ensembl chr 7:113,274,015...113,279,105
JBrowse link
G EP300 E1A binding protein p300 ISO (MGI:MGI:3812266|PMID:18684867) MGI PMID:18684867 MGI:MGI:3812266 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO (MGI:MGI:5484711|PMID:23531880) MGI PMID:23531880 MGI:MGI:5484711 NCBI chr 7:140,536,962...140,613,104
Ensembl chr 7:153,017,590...153,059,726
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ISO (MGI:MGI:4946600|PMID:21228325) UniProtKB PMID:21228325 MGI:MGI:4946600 NCBI chr13:9,283,747...9,381,553
Ensembl chr13:27,627,178...27,723,940
JBrowse link
G FZD9 frizzled class receptor 9 ISO (MGI:MGI:3577530|PMID:15572594) MGI PMID:15572594 MGI:MGI:3577530 Ensembl chr 7:80,588,167...80,590,337 JBrowse link
G GIMAP1 GTPase, IMAP family member 1 ISO (MGI:MGI:4455099|PMID:20194894) MGI PMID:20194894 MGI:MGI:4455099 NCBI chr 7:142,299,040...142,303,621 JBrowse link
G GON4L gon-4 like ISO (MGI:MGI:4821908|PMID:20530203) MGI PMID:20530203 MGI:MGI:4821908 NCBI chr 1:131,084,009...131,193,884
Ensembl chr 1:134,917,791...135,020,042
JBrowse link
G GPS2 G protein pathway suppressor 2 ISO (MGI:MGI:5896692|PMID:28039360) UniProtKB PMID:28039360 MGI:MGI:5896692 NCBI chr17:7,346,766...7,349,682
Ensembl chr17:7,333,571...7,335,871
JBrowse link
G HHEX hematopoietically expressed homeobox ISO (MGI:MGI:2449266|PMID:12522149) MGI PMID:12522149 MGI:MGI:2449266 NCBI chr10:89,433,402...89,439,137
Ensembl chr10:92,947,373...92,952,992
JBrowse link
G IKZF1 IKAROS family zinc finger 1 ISO (MGI:MGI:5449477|PMID:23071339)
(MGI:MGI:68746|PMID:7923373)
MGI PMID:7923373, PMID:23071339 MGI:MGI:5449477, MGI:MGI:68746 NCBI chr 7:50,946,817...51,047,168
Ensembl chr 7:51,191,685...51,291,245
JBrowse link
G JAK3 Janus kinase 3 ISO (MGI:MGI:3655405|PMID:9498750) BHF-UCL PMID:9498750 MGI:MGI:3655405 NCBI chr19:17,299,129...17,330,700
Ensembl chr19:18,283,560...18,300,964
JBrowse link
G LYL1 LYL1 basic helix-loop-helix family member ISO (MGI:MGI:3693935|PMID:16514064) UniProtKB PMID:16514064 MGI:MGI:3693935 NCBI chr19:12,660,548...12,664,513
Ensembl chr19:13,407,596...13,409,309
JBrowse link
G MS4A1 membrane spanning 4-domains A1 ISO (PMID:3925015) UniProt PMID:3925015 NCBI chr11:55,691,750...55,706,697
Ensembl chr11:59,134,617...59,149,521
JBrowse link
G MSH2 mutS homolog 2 ISO (MGI:MGI:1275867|PMID:9697843) MGI PMID:9697843 MGI:MGI:1275867 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461
JBrowse link
G MYB MYB proto-oncogene, transcription factor ISO (MGI:MGI:3763573|PMID:17927961) MGI PMID:17927961 MGI:MGI:3763573 NCBI chr 6:132,952,728...132,990,560
Ensembl chr 6:137,048,812...137,086,194
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 ISO (MGI:MGI:3044463|PMID:15143214) HGNC PMID:15143214 MGI:MGI:3044463 NCBI chr22:23,276,675...23,332,932
Ensembl chr22:41,345,206...41,396,721
JBrowse link
G NHEJ1 non-homologous end joining factor 1 ISO (PMID:16439204) UniProtKB PMID:16439204 NCBI chr2B:106,326,596...106,419,928
Ensembl chr2B:224,926,183...225,008,788
JBrowse link
G NKX2-3 NK2 homeobox 3 ISO (MGI:MGI:2654966|PMID:12682228) MGI PMID:12682228 MGI:MGI:2654966 NCBI chr10:96,146,636...96,150,238 JBrowse link
G ONECUT1 one cut homeobox 1 ISO (MGI:MGI:3707632|PMID:12874218) MGI PMID:12874218 MGI:MGI:3707632 NCBI chr15:31,694,830...31,727,644
Ensembl chr15:50,016,010...50,053,062
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO (MGI:MGI:1329776|PMID:9988280) MGI PMID:9988280 MGI:MGI:1329776 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960
JBrowse link
G PLCG2 phospholipase C gamma 2 ISO (MGI:MGI:1861532|PMID:10925250) UniProtKB PMID:10925250 MGI:MGI:1861532 NCBI chr16:62,383,270...62,561,579
Ensembl chr16:81,812,565...81,984,064
JBrowse link
G POLM DNA polymerase mu ISO (MGI:MGI:3576407|PMID:15789338) MGI PMID:15789338 MGI:MGI:3576407 NCBI chr 7:44,785,797...44,796,624 JBrowse link
G POU1F1 POU class 1 homeobox 1 ISO (MGI:MGI:3640879|PMID:9300691) MGI PMID:9300691 MGI:MGI:3640879 NCBI chr 3:87,390,157...87,407,611
Ensembl chr 3:89,501,298...89,521,168
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 ISO (MGI:MGI:1096020|PMID:9271584) UniProtKB PMID:9271584 MGI:MGI:1096020 NCBI chr18:1,440,837...1,538,501
Ensembl chr18:16,562,052...16,659,570
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C ISO (MGI:MGI:3521537|PMID:15557316), (MGI:MGI:3774343|PMID:18249142)
(MGI:MGI:1095647|PMID:9254656)
(MGI:MGI:2670259|PMID:12902479), (MGI:MGI:80946|PMID:8666928)
ARUK-UCL
MGI
PMID:8666928, PMID:9254656, PMID:12902479, PMID:15557316, PMID:18249142 MGI:MGI:1095647, MGI:MGI:2670259, MGI:MGI:3521537, MGI:MGI:3774343, MGI:MGI:80946 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J ISO (MGI:MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:MGI:3774343 NCBI chr11:47,941,134...48,130,538
Ensembl chr11:48,613,761...48,670,494
JBrowse link
G RABL3 RAB, member of RAS oncogene family like 3 ISO (MGI:MGI:6405642|PMID:32220963) UniProt PMID:32220963 MGI:MGI:6405642 NCBI chr 3:117,794,224...117,850,184
Ensembl chr 3:124,707,984...124,748,983
JBrowse link
G RAG1 recombination activating 1 ISO (MGI:MGI:2178701|PMID:11976687)
(MGI:MGI:50458|PMID:1547488)
MGI
UniProtKB
PMID:1547488, PMID:11976687 MGI:MGI:2178701, MGI:MGI:50458 NCBI chr11:36,483,697...36,546,242
Ensembl chr11:36,412,420...36,422,904
JBrowse link
G RAG2 recombination activating 2 ISO (MGI:MGI:50458|PMID:1547488), (MGI:MGI:50459|PMID:1547487)
(MGI:MGI:2179579|PMID:11980719), (MGI:MGI:3709144|PMID:14595002)
UniProtKB
MGI
PMID:1547487, PMID:1547488, PMID:11980719, PMID:14595002 MGI:MGI:2179579, MGI:MGI:3709144, MGI:MGI:50458, MGI:MGI:50459 NCBI chr11:36,558,419...36,564,997
Ensembl chr11:36,431,703...36,433,286
JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:MGI:2178898|PMID:11967543) MGI PMID:11967543 MGI:MGI:2178898 NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683
JBrowse link
G SP3 Sp3 transcription factor ISO (MGI:MGI:2670314|PMID:12676787) MGI PMID:12676787 MGI:MGI:2670314 NCBI chr2B:61,185,975...61,243,155
Ensembl chr2B:178,639,677...178,692,848
JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 ISO (MGI:MGI:3054344|PMID:15294947)
(MGI:MGI:3055645|PMID:15284856), (MGI:MGI:3655025|PMID:16797412)
MGI PMID:15284856, PMID:15294947, PMID:16797412 MGI:MGI:3054344, MGI:MGI:3055645, MGI:MGI:3655025 NCBI chr11:63,120,913...63,132,831
Ensembl chr11:66,429,435...66,441,327
JBrowse link
G TPD52 tumor protein D52 ISO (PMID:15576473) UniProtKB PMID:15576473 NCBI chr 8:76,562,979...76,698,329 JBrowse link
G TSHR thyroid stimulating hormone receptor ISO (MGI:MGI:3640879|PMID:9300691) MGI PMID:9300691 MGI:MGI:3640879 NCBI chr14:61,517,767...61,708,241
Ensembl chr14:80,718,433...80,905,890
JBrowse link
G YY1 YY1 transcription factor ISO (MGI:MGI:5484711|PMID:23531880) MGI PMID:23531880 MGI:MGI:5484711 NCBI chr14:80,859,491...80,903,651 JBrowse link
G ZBTB1 zinc finger and BTB domain containing 1 ISO (MGI:MGI:5300225|PMID:22201126) MGI PMID:22201126 MGI:MGI:5300225 NCBI chr14:45,085,146...45,114,965
Ensembl chr14:63,354,458...63,359,403
JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A ISO (MGI:MGI:3710692|PMID:17495164) UniProt PMID:17495164 MGI:MGI:3710692 NCBI chr19:3,066,554...3,090,285 JBrowse link
B cell affinity maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase ISO (MGI:MGI:65977|PMID:7680896) MGI PMID:7680896 MGI:MGI:65977 NCBI chr  X:90,551,874...90,588,786
Ensembl chr  X:100,684,017...100,725,187
JBrowse link
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain ISO (MGI:MGI:4943414|PMID:1378867) BHF-UCL PMID:1378867 MGI:MGI:4943414 NCBI chr 6:32,237,395...32,244,201
Ensembl chr 6:33,353,599...33,360,272
JBrowse link
B cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator ISO (MGI:MGI:78866|PMID:8788039) MGI PMID:8788039 MGI:MGI:78866 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit ISO (MGI:MGI:78866|PMID:8788039) MGI PMID:8788039 MGI:MGI:78866 NCBI chr 8:44,201,391...44,386,803
Ensembl chr 8:41,593,029...41,778,299
JBrowse link
G RAG2 recombination activating 2 ISO (MGI:MGI:78866|PMID:8788039) MGI PMID:8788039 MGI:MGI:78866 NCBI chr11:36,558,419...36,564,997
Ensembl chr11:36,431,703...36,433,286
JBrowse link
G TCF3 transcription factor 3 ISO (PMID:15030778) UniProtKB PMID:15030778 Ensembl chr19:1,582,297...1,622,025 JBrowse link
G TP53 tumor protein p53 ISO (MGI:MGI:78866|PMID:8788039) MGI PMID:8788039 MGI:MGI:78866 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
B cell negative selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 ISO (MGI:MGI:3588597|PMID:16055554) MGI PMID:16055554 MGI:MGI:3588597 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211
JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO (MGI:MGI:3588597|PMID:16055554) MGI PMID:16055554 MGI:MGI:3588597 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
B-1 B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD19 CD19 molecule ISO (MGI:MGI:74944|PMID:7543183) UniProt PMID:7543183 MGI:MGI:74944 Ensembl chr16:29,320,734...29,327,481 JBrowse link
G MALT1 MALT1 paracaspase ISO (MGI:MGI:3629264|PMID:14614861) MGI PMID:14614861 MGI:MGI:3629264 NCBI chr18:52,060,878...52,141,985
Ensembl chr18:55,395,462...55,473,574
JBrowse link
B-1 B cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLAMF8 SLAM family member 8 ISO (MGI:MGI:6215454|PMID:11313408) UniProt PMID:11313408 MGI:MGI:6215454 NCBI chr 1:135,178,241...135,189,005 JBrowse link
B-1a B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMTM7 CKLF like MARVEL transmembrane domain containing 7 ISO (MGI:MGI:5554324|PMID:24080084) MGI PMID:24080084 MGI:MGI:5554324 NCBI chr 3:32,308,975...32,372,711 JBrowse link
G NFATC1 nuclear factor of activated T cells 1 ISO (MGI:MGI:2680742|PMID:14595020) MGI PMID:14595020 MGI:MGI:2680742 NCBI chr18:72,948,067...73,083,180
Ensembl chr18:76,017,454...76,094,453
JBrowse link
G PLCL2 phospholipase C like 2 ISO (MGI:MGI:2677607|PMID:14517301) MGI PMID:14517301 MGI:MGI:2677607 NCBI chr 3:16,736,430...17,015,531
Ensembl chr 3:17,154,500...17,351,287
JBrowse link
follicular B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLCG2 phospholipase C gamma 2 ISO (MGI:MGI:2679743|PMID:12928432) MGI PMID:12928432 MGI:MGI:2679743 NCBI chr16:62,383,270...62,561,579
Ensembl chr16:81,812,565...81,984,064
JBrowse link
germinal center B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO (MGI:MGI:3619310|PMID:14607964) MGI PMID:14607964 MGI:MGI:3619310 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868
JBrowse link
G CDH17 cadherin 17 ISO (MGI:MGI:3531365|PMID:15688343) UniProtKB PMID:15688343 MGI:MGI:3531365 NCBI chr 8:90,750,904...90,818,629
Ensembl chr 8:92,696,182...92,760,732
JBrowse link
G IL21 interleukin 21 ISO (MGI:MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:MGI:5450752 NCBI chr 4:114,795,979...114,806,936
Ensembl chr 4:125,943,495...125,951,915
JBrowse link
G IL6 interleukin 6 ISO (MGI:MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:MGI:5450752 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G ITFG2 integrin alpha FG-GAP repeat containing 2 ISO (MGI:MGI:5547463|PMID:23997217) MGI PMID:23997217 MGI:MGI:5547463 NCBI chr12:2,933,227...2,980,509
Ensembl chr12:2,865,297...2,877,555
JBrowse link
G POU2AF1 POU class 2 homeobox associating factor 1 ISO (MGI:MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:MGI:5450752 NCBI chr11:106,231,870...106,258,822
Ensembl chr11:110,078,850...110,103,996
JBrowse link
immature B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FNIP1 folliculin interacting protein 1 ISO (MGI:MGI:5436190|PMID:22608497) MGI PMID:22608497 MGI:MGI:5436190 NCBI chr 5:127,070,906...127,219,548
Ensembl chr 5:133,235,501...133,384,218
JBrowse link
G IRF2BP2 interferon regulatory factor 2 binding protein 2 ISO (PMID:27016798) UniProtKB PMID:27016798 NCBI chr 1:210,143,516...210,148,878 JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO (MGI:MGI:3040777|PMID:15067126) UniProtKB PMID:15067126 MGI:MGI:3040777 NCBI chr 4:69,199,543...69,282,323
Ensembl chr 4:75,761,946...75,844,473
JBrowse link
G SYVN1 synoviolin 1 ISO (MGI:MGI:6220623|PMID:29907570) UniProt PMID:29907570 MGI:MGI:6220623 NCBI chr11:60,489,626...60,496,945
Ensembl chr11:63,829,138...63,834,364
JBrowse link
marginal zone B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL3 BCL3 transcription coactivator ISO (MGI:MGI:85481|PMID:9009202) MGI PMID:9009202 MGI:MGI:85481 NCBI chr19:41,696,162...41,708,485
Ensembl chr19:50,304,171...50,313,005
JBrowse link
G CDH17 cadherin 17 ISO (MGI:MGI:3531365|PMID:15688343) UniProtKB PMID:15688343 MGI:MGI:3531365 NCBI chr 8:90,750,904...90,818,629
Ensembl chr 8:92,696,182...92,760,732
JBrowse link
G DLL1 delta like canonical Notch ligand 1 ISO (MGI:MGI:3044313|PMID:15146182), (MGI:MGI:3838059|PMID:19217325) UniProtKB PMID:15146182, PMID:19217325 MGI:MGI:3044313, MGI:MGI:3838059 NCBI chr 6:168,440,192...168,449,071
Ensembl chr 6:173,534,292...173,544,759
JBrowse link
G DOCK10 dedicator of cytokinesis 10 ISO (MGI:MGI:5818419|PMID:25729399) UniProtKB PMID:25729399 MGI:MGI:5818419 NCBI chr2B:112,006,479...112,283,939
Ensembl chr2B:230,578,452...230,854,877
JBrowse link
G DOCK11 dedicator of cytokinesis 11 ISO (MGI:MGI:5818419|PMID:25729399) UniProtKB PMID:25729399 MGI:MGI:5818419 NCBI chr  X:107,502,955...107,694,069
Ensembl chr  X:117,952,995...118,161,009
JBrowse link
G LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase ISO (MGI:MGI:3838059|PMID:19217325) UniProtKB PMID:19217325 MGI:MGI:3838059 NCBI chr 7:2,781,493...2,790,936 JBrowse link
G MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase ISO (MGI:MGI:3838059|PMID:19217325) UniProtKB PMID:19217325 MGI:MGI:3838059 NCBI chr22:18,385,664...18,407,056
Ensembl chr22:36,218,403...36,239,804
JBrowse link
G NOTCH2 notch receptor 2 ISO (MGI:MGI:3838059|PMID:19217325) UniProtKB PMID:19217325 MGI:MGI:3838059 NCBI chr 1:82,457,829...82,615,142
Ensembl chr 1:117,538,243...117,612,840
JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO (MGI:MGI:1860716|PMID:10881171) UniProtKB PMID:10881171 MGI:MGI:1860716 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474
JBrowse link
mature B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU2F2 POU class 2 homeobox 2 ISO (MGI:MGI:53043|PMID:8096198) MGI PMID:8096198 MGI:MGI:53043 NCBI chr19:38,974,635...39,065,103 JBrowse link
mature B cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C17H17orf99 chromosome 17 C17orf99 homolog ISO (MGI:MGI:6103709|PMID:28978694) UniProtKB PMID:28978694 MGI:MGI:6103709 NCBI chr17:72,223,073...72,244,049
Ensembl chr17:77,776,151...77,796,139
JBrowse link
G GPR183 G protein-coupled receptor 183 ISO (MGI:MGI:4352759|PMID:19597478) UniProtKB PMID:19597478 MGI:MGI:4352759 NCBI chr13:80,461,908...80,475,046
Ensembl chr13:99,601,220...99,602,305
JBrowse link
memory B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 ISO (MGI:MGI:2387354|PMID:10755614) UniProt PMID:10755614 MGI:MGI:2387354 NCBI chr 8:130,111,085...130,227,195
Ensembl chr 8:133,084,835...133,119,791
JBrowse link
negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT3 fms related receptor tyrosine kinase 3 ISO (MGI:MGI:3623701|PMID:16618805) MGI PMID:16618805 MGI:MGI:3623701 NCBI chr13:9,283,747...9,381,553
Ensembl chr13:27,627,178...27,723,940
JBrowse link
G HMGB3 high mobility group box 3 ISO (MGI:MGI:2670545|PMID:12714519) MGI PMID:12714519 MGI:MGI:2670545 NCBI chr  X:140,632,163...140,639,774 JBrowse link
G ID2 inhibitor of DNA binding 2 ISO (MGI:MGI:3805135|PMID:18523151) MGI PMID:18523151 MGI:MGI:3805135 NCBI chr2A:8,681,592...8,684,014
Ensembl chr2A:8,847,776...8,850,720
JBrowse link
G SFRP1 secreted frizzled related protein 1 ISO (PMID:18941195)
(MGI:MGI:3814493|PMID:18941195)
UniProtKB PMID:18941195 MGI:MGI:3814493 NCBI chr 8:40,507,027...40,555,053 JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CR1 complement C3b/C4b receptor 1 (Knops blood group) ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr 1:183,094,601...183,246,957 JBrowse link
plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITM2A integral membrane protein 2A ISO (MGI:MGI:5613782|PMID:24831988) MGI PMID:24831988 MGI:MGI:5613782 NCBI chr  X:68,475,114...68,482,274
Ensembl chr  X:78,585,836...78,593,037
JBrowse link
G LGALS1 galectin 1 ISO (MGI:MGI:5301217|PMID:21753146) MGI PMID:21753146 MGI:MGI:5301217 NCBI chr22:18,593,154...18,597,432
Ensembl chr22:36,426,228...36,430,356
JBrowse link
G LGALS8 galectin 8 ISO (MGI:MGI:5301217|PMID:21753146) MGI PMID:21753146 MGI:MGI:5301217 NCBI chr 1:212,083,584...212,112,182 JBrowse link
G NKX2-3 NK2 homeobox 3 ISO (MGI:MGI:1888604|PMID:10926756) MGI PMID:10926756 MGI:MGI:1888604 NCBI chr10:96,146,636...96,150,238 JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP11C ATPase phospholipid transporting 11C ISO (MGI:MGI:5002406|PMID:21423173) UniProtKB PMID:21423173 MGI:MGI:5002406 NCBI chr  X:128,880,747...129,085,989
Ensembl chr  X:139,132,783...139,334,869
JBrowse link
G BAD BCL2 associated agonist of cell death ISO (MGI:MGI:3029504|PMID:12431371) MGI PMID:12431371 MGI:MGI:3029504 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G IL2RG interleukin 2 receptor subunit gamma ISO (MGI:MGI:1095961|PMID:9252128) MGI PMID:9252128 MGI:MGI:1095961 NCBI chr  X:60,375,815...60,386,936 JBrowse link
G IL7 interleukin 7 ISO (MGI:MGI:3655025|PMID:16797412) MGI PMID:16797412 MGI:MGI:3655025 NCBI chr 8:75,254,166...75,337,373
Ensembl chr 8:76,895,095...76,966,918
JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D ISO (MGI:MGI:1266928|PMID:9620849), (MGI:MGI:1354084|PMID:10704460) MGI PMID:9620849, PMID:10704460 MGI:MGI:1266928, MGI:MGI:1354084 NCBI chr2B:120,287,606...120,436,526
Ensembl chr2B:239,201,762...239,350,190
JBrowse link
G LOC100988550 signal transducer and activator of transcription 5A ISO (MGI:MGI:1889695|PMID:10979977) MGI PMID:10979977 MGI:MGI:1889695 NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783
JBrowse link
G LOC100989105 signal transducer and activator of transcription 5B ISO (MGI:MGI:1889695|PMID:10979977) MGI PMID:10979977 MGI:MGI:1889695 NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463
JBrowse link
G MMP14 matrix metallopeptidase 14 ISO (MGI:MGI:5013661|PMID:21572390) UniProtKB PMID:21572390 MGI:MGI:5013661 NCBI chr14:3,654,125...3,665,158
Ensembl chr14:21,753,305...21,764,058
JBrowse link
G NCKAP1L NCK associated protein 1 like ISO (MGI:MGI:3818191|PMID:19015308) UniProtKB PMID:19015308 MGI:MGI:3818191 NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881
JBrowse link
G PCID2 PCI domain containing 2 ISO (MGI:MGI:4839685|PMID:20870947) UniProtKB PMID:20870947 MGI:MGI:4839685 NCBI chr13:94,319,699...94,350,763
Ensembl chr13:113,388,251...113,419,251
JBrowse link
G PPP2R3C protein phosphatase 2 regulatory subunit B''gamma ISO (MGI:MGI:3589325|PMID:16129705) MGI PMID:16129705 MGI:MGI:3589325 NCBI chr14:15,834,603...15,871,741
Ensembl chr14:34,020,893...34,056,842
JBrowse link
G PRDM1 PR/SET domain 1 NOT ISO (MGI:MGI:3826899|PMID:18845144) MGI PMID:18845144 MGI:MGI:3826899 NCBI chr 6:103,899,410...103,923,389
Ensembl chr 6:107,773,229...107,796,815
JBrowse link
G SYK spleen associated tyrosine kinase ISO (PMID:18369315)
(MGI:MGI:77315|PMID:7477353)
(MGI:MGI:77314|PMID:7477352)
CACAO
MGI
PMID:7477352, PMID:7477353, PMID:18369315 MGI:MGI:77314, MGI:MGI:77315 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101
JBrowse link
G XBP1 X-box binding protein 1 ISO (PMID:11460154) UniProtKB PMID:11460154 NCBI chr22:9,863,479...9,869,491 JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL2 interleukin 2 ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G XBP1 X-box binding protein 1 ISO (PMID:11460154) UniProtKB PMID:11460154 NCBI chr22:9,863,479...9,869,491 JBrowse link
pre-B cell allelic exclusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase ISO (MGI:MGI:3848557|PMID:19448632) UniProtKB PMID:19448632 MGI:MGI:3848557 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041
JBrowse link
G RAG1 recombination activating 1 ISO (MGI:MGI:3848557|PMID:19448632) UniProtKB PMID:19448632 MGI:MGI:3848557 NCBI chr11:36,483,697...36,546,242
Ensembl chr11:36,412,420...36,422,904
JBrowse link
G RAG2 recombination activating 2 ISO (MGI:MGI:3848557|PMID:19448632) UniProtKB PMID:19448632 MGI:MGI:3848557 NCBI chr11:36,558,419...36,564,997
Ensembl chr11:36,431,703...36,433,286
JBrowse link
pre-B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP11C ATPase phospholipid transporting 11C ISO (MGI:MGI:5002406|PMID:21423173) UniProtKB PMID:21423173 MGI:MGI:5002406 NCBI chr  X:128,880,747...129,085,989
Ensembl chr  X:139,132,783...139,334,869
JBrowse link
G CD24 CD24 molecule ISO (MGI:MGI:2179980|PMID:9028339), (MGI:MGI:74794|PMID:7795661) MGI PMID:7795661, PMID:9028339 MGI:MGI:2179980, MGI:MGI:74794 NCBI chr 6:104,783,720...104,789,509
Ensembl chr 6:108,655,624...108,657,847
JBrowse link
G FOXP1 forkhead box P1 ISO (MGI:MGI:3662963|PMID:16819554) MGI PMID:16819554 MGI:MGI:3662963 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173
JBrowse link
regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKLE1 ankyrin repeat and LEM domain containing 1 NOT ISO (MGI:MGI:5800654|PMID:27010503) UniProtKB PMID:27010503 MGI:MGI:5800654 NCBI chr19:16,769,670...16,775,114
Ensembl chr19:17,744,570...17,750,070
JBrowse link
G CARD11 caspase recruitment domain family member 11 ISO (MGI:MGI:3039643|PMID:12867038) MGI PMID:12867038 MGI:MGI:3039643 NCBI chr 7:3,166,788...3,304,729
Ensembl chr 7:3,258,736...3,332,999
JBrowse link
G CD24 CD24 molecule ISO (MGI:MGI:2179980|PMID:9028339), (MGI:MGI:74794|PMID:7795661) MGI PMID:7795661, PMID:9028339 MGI:MGI:2179980, MGI:MGI:74794 NCBI chr 6:104,783,720...104,789,509
Ensembl chr 6:108,655,624...108,657,847
JBrowse link
G CYLD CYLD lysine 63 deubiquitinase ISO (MGI:MGI:3656194|PMID:16501569) MGI PMID:16501569 MGI:MGI:3656194 NCBI chr16:31,004,393...31,064,546
Ensembl chr16:49,882,751...49,942,629
JBrowse link
G FCRL3 Fc receptor like 3 ISO (PMID:23857366) UniProtKB PMID:23857366 NCBI chr 1:133,038,100...133,062,467
Ensembl chr 1:136,830,553...136,855,027
JBrowse link
G LOC100975642 zinc finger protein Aiolos ISO (MGI:MGI:1307021|PMID:9806640) UniProtKB PMID:9806640 MGI:MGI:1307021 NCBI chr17:17,459,438...17,498,452
Ensembl chr17:17,643,750...17,741,479
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 ISO (MGI:MGI:3044463|PMID:15143214) MGI PMID:15143214 MGI:MGI:3044463 NCBI chr22:23,276,675...23,332,932
Ensembl chr22:41,345,206...41,396,721
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 ISO (MGI:MGI:1095647|PMID:9254656) MGI PMID:9254656 MGI:MGI:1095647 NCBI chr12:7,075,879...7,093,041
Ensembl chr12:6,991,099...7,008,830
JBrowse link
G SLAMF8 SLAM family member 8 ISO (MGI:MGI:6215454|PMID:11313408) UniProt PMID:11313408 MGI:MGI:6215454 NCBI chr 1:135,178,241...135,189,005 JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 ISO (MGI:MGI:5779430|PMID:27102483) UniProtKB PMID:27102483 MGI:MGI:5779430 NCBI chr14:49,372,058...49,379,116
Ensembl chr14:68,247,347...68,255,805
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 ISO (MGI:MGI:5779430|PMID:27102483) UniProtKB PMID:27102483 MGI:MGI:5779430 NCBI chr2A:43,311,744...43,315,928 JBrowse link
transitional one stage B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO (MGI:MGI:3839222|PMID:19228876) MGI PMID:19228876 MGI:MGI:3839222 NCBI chr 9:101,834,189...102,005,811
Ensembl chr 9:130,484,333...130,652,941
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12564
    immune system process 2076
      leukocyte activation 843
        lymphocyte activation 679
          lymphocyte differentiation 360
            B cell differentiation 119
              B cell lineage commitment + 6
              B cell selection + 4
              immature B cell differentiation + 11
              mature B cell differentiation + 33
              negative regulation of B cell differentiation + 5
              positive regulation of B cell differentiation + 16
              regulation of B cell differentiation + 32
Path 2
Term Annotations click to browse term
  biological_process 12564
    developmental process 5839
      anatomical structure development 5452
        multicellular organism development 4984
          system development 4688
            immune system development 967
              hematopoietic or lymphoid organ development 906
                hemopoiesis 858
                  leukocyte differentiation 538
                    lymphocyte differentiation 360
                      B cell differentiation 119
                        B cell lineage commitment + 6
                        B cell selection + 4
                        immature B cell differentiation + 11
                        mature B cell differentiation + 33
                        negative regulation of B cell differentiation + 5
                        positive regulation of B cell differentiation + 16
                        regulation of B cell differentiation + 32
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.