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ONTOLOGY REPORT - ANNOTATIONS


Term:B cell differentiation
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Accession:GO:0030183 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: B lymphocyte differentiation
 related_synonym: B cell development
 alt_id: GO:0042115


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B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 ISO (MGI:MGI:3828349|PMID:17371977) BHF-UCL PMID:17371977 MGI:MGI:3828349 NCBI chr17:6,589,874...6,638,788
Ensembl chr17:6,589,878...6,638,731
JBrowse link
G ADGRG3 adhesion G protein-coupled receptor G3 IEA Ensembl GO_REF:0000107 NCBI chr 2:58,780,800...58,805,593
Ensembl chr 2:58,781,680...58,802,534
JBrowse link
G BCL11A BAF chromatin remodeling complex subunit BCL11A ISO (MGI:MGI:2662805|PMID:12717432) MGI PMID:12717432 MGI:MGI:2662805 NCBI chr10:60,589,298...60,691,997
Ensembl chr10:60,589,708...60,689,073
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO (MGI:MGI:2156164|PMID:8170972), (MGI:MGI:85476|PMID:9028316) MGI PMID:8170972, PMID:9028316 MGI:MGI:2156164, MGI:MGI:85476 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G BCL6 BCL6 transcription repressor IEA Ensembl GO_REF:0000107 NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704
JBrowse link
G CARD11 caspase recruitment domain family member 11 IEA Ensembl GO_REF:0000107 NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094
JBrowse link
G CD40LG CD40 ligand IEA Ensembl GO_REF:0000107 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006
JBrowse link
G CD79A CD79a molecule IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 1:112,411,281...112,414,827
Ensembl chr 1:112,411,281...112,427,381
JBrowse link
G CD79B CD79b molecule IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:11,834,230...11,844,946
Ensembl chr 9:11,842,190...11,844,843
JBrowse link
G CDH17 cadherin 17 ISO (MGI:MGI:3531365|PMID:15688343) UniProtKB PMID:15688343 MGI:MGI:3531365 NCBI chr29:38,918,098...38,980,709
Ensembl chr29:38,918,574...38,977,217
JBrowse link
G CEBPG CCAAT enhancer binding protein gamma IEA Ensembl GO_REF:0000107 NCBI chr 1:118,777,110...118,784,397
Ensembl chr 1:118,778,224...118,778,667
JBrowse link
G CLCF1 cardiotrophin like cytokine factor 1 ISO (MGI:MGI:1346205|PMID:10500198) MGI PMID:10500198 MGI:MGI:1346205 NCBI chr18:50,084,120...50,093,825
Ensembl chr18:50,083,915...50,102,651
JBrowse link
G CR2 complement C3d receptor 2 ISO (PMID:2995485) UniProtKB PMID:2995485 NCBI chr 7:6,456,238...6,480,672 JBrowse link
G DCAF1 DDB1 and CUL4 associated factor 1 IEA Ensembl GO_REF:0000107 NCBI chr20:38,109,974...38,187,621
Ensembl chr20:38,125,078...38,187,107
JBrowse link
G DCLRE1C DNA cross-link repair 1C IEA Ensembl GO_REF:0000107 NCBI chr 2:21,688,822...21,725,021
Ensembl chr 2:21,688,766...21,724,248
JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 IEA Ensembl GO_REF:0000107 NCBI chr14:48,879,963...48,885,616
Ensembl chr14:48,879,914...48,884,361
JBrowse link
G EP300 E1A binding protein p300 IEA Ensembl GO_REF:0000107 NCBI chr10:24,076,538...24,156,708
Ensembl chr10:24,077,971...24,156,396
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO (MGI:MGI:5484711|PMID:23531880) MGI PMID:23531880 MGI:MGI:5484711 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284
JBrowse link
G FZD9 frizzled class receptor 9 IEA Ensembl GO_REF:0000107 NCBI chr 6:6,782,394...6,784,565
Ensembl chr 6:6,782,774...6,784,558
JBrowse link
G GIMAP1 GTPase, IMAP family member 1 ISO (MGI:MGI:4455099|PMID:20194894) MGI PMID:20194894 MGI:MGI:4455099 NCBI chr16:14,793,642...14,798,501
Ensembl chr16:14,793,464...14,795,732
JBrowse link
G GON4L gon-4 like IEA InterPro GO_REF:0000002 NCBI chr 7:41,927,667...42,000,649 JBrowse link
G GPS2 G protein pathway suppressor 2 IEA Ensembl GO_REF:0000107 NCBI chr 5:32,273,169...32,275,915
Ensembl chr 5:32,273,173...32,275,580
JBrowse link
G HHEX hematopoietically expressed homeobox ISO (MGI:MGI:2449266|PMID:12522149) MGI PMID:12522149 MGI:MGI:2449266 NCBI chr28:7,057,379...7,063,326
Ensembl chr28:7,057,283...7,063,330
JBrowse link
G IFNA5 interferon, alpha 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:40,726,568...40,727,131
Ensembl chr11:40,726,568...40,727,131
JBrowse link
G IFNA7 interferon, alpha 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:40,862,587...40,863,150
Ensembl chr11:40,862,587...40,863,150
JBrowse link
G IFNK interferon kappa IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:45,641,627...45,642,256
Ensembl chr11:45,641,627...45,642,256
JBrowse link
G IKZF1 IKAROS family zinc finger 1 ISO (MGI:MGI:5449477|PMID:23071339)
(MGI:MGI:68746|PMID:7923373)
MGI PMID:7923373, PMID:23071339 MGI:MGI:5449477, MGI:MGI:68746 NCBI chr18:1,661,851...1,750,987
Ensembl chr18:1,661,690...1,770,768
JBrowse link
G JAK3 Janus kinase 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
JBrowse link
G LOC100685213 interferon alpha-1/2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:40,816,731...40,817,513 JBrowse link
G LOC100685589 DNA-directed DNA/RNA polymerase mu-like ISO (MGI:MGI:3576407|PMID:15789338) MGI PMID:15789338 MGI:MGI:3576407
G LOC100687928 interferon alpha-1/2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:40,749,643...40,750,398 JBrowse link
G LOC100688084 interferon alpha-1/2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:40,765,515...40,766,521 JBrowse link
G LYL1 LYL1 basic helix-loop-helix family member ISO (MGI:MGI:3693935|PMID:16514064) UniProtKB PMID:16514064 MGI:MGI:3693935 NCBI chr20:49,109,358...49,113,911 JBrowse link
G MS4A1 membrane spanning 4-domains A1 IEA Ensembl GO_REF:0000107 NCBI chr21:50,722,142...50,734,934
Ensembl chr21:50,722,041...50,733,704
JBrowse link
G MSH2 mutS homolog 2 IEA Ensembl GO_REF:0000107 NCBI chr10:49,517,448...49,594,001
Ensembl chr10:49,517,369...49,594,210
JBrowse link
G MYB MYB proto-oncogene, transcription factor ISO (MGI:MGI:3763573|PMID:17927961) MGI PMID:17927961 MGI:MGI:3763573 NCBI chr 1:27,908,309...27,991,984
Ensembl chr 1:27,908,364...27,991,969
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 ISO (MGI:MGI:3044463|PMID:15143214) HGNC PMID:15143214 MGI:MGI:3044463 NCBI chr10:23,008,084...23,047,227
Ensembl chr10:23,008,393...23,045,565
JBrowse link
G NHEJ1 non-homologous end joining factor 1 IEA Ensembl GO_REF:0000107 NCBI chr37:25,637,214...25,719,241
Ensembl chr37:25,637,601...25,715,372
JBrowse link
G NKX2-3 NK2 homeobox 3 ISO (MGI:MGI:2654966|PMID:12682228) MGI PMID:12682228 MGI:MGI:2654966 NCBI chr28:12,466,319...12,469,467
Ensembl chr28:12,466,368...12,469,473
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:41,140,931...41,159,326
Ensembl chr 7:41,140,879...41,159,288
JBrowse link
G ONECUT1 one cut homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr30:18,384,533...18,425,940
Ensembl chr30:18,387,130...18,425,497
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970
JBrowse link
G PLCG2 phospholipase C gamma 2 ISO (MGI:MGI:1861532|PMID:10925250) UniProtKB PMID:10925250 MGI:MGI:1861532 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049
JBrowse link
G POU1F1 POU class 1 homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr31:769,454...788,761
Ensembl chr31:769,487...787,626
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C IEA Ensembl GO_REF:0000107 NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J ISO (MGI:MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:MGI:3774343 NCBI chr18:41,586,262...41,635,386
Ensembl chr18:41,586,112...41,635,308
JBrowse link
G RABL3 RAB, member of RAS oncogene family like 3 ISO (MGI:MGI:6405642|PMID:32220963) UniProt PMID:32220963 MGI:MGI:6405642 NCBI chr33:24,107,754...24,151,378
Ensembl chr33:24,066,306...24,151,354
JBrowse link
G RAG1 recombination activating 1 ISO (MGI:MGI:2178701|PMID:11976687)
(MGI:MGI:50458|PMID:1547488)
MGI
UniProtKB
PMID:1547488, PMID:11976687 MGI:MGI:2178701, MGI:MGI:50458 NCBI chr18:31,628,231...31,639,980
Ensembl chr18:31,630,737...31,641,660
JBrowse link
G RAG2 recombination activating 2 ISO (MGI:MGI:50458|PMID:1547488), (MGI:MGI:50459|PMID:1547487)
(MGI:MGI:2179579|PMID:11980719), (MGI:MGI:3709144|PMID:14595002)
UniProtKB
MGI
PMID:1547487, PMID:1547488, PMID:11980719, PMID:14595002 MGI:MGI:2179579, MGI:MGI:3709144, MGI:MGI:50458, MGI:MGI:50459 NCBI chr18:31,614,143...31,621,489
Ensembl chr18:31,618,481...31,620,064
JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region IEA Ensembl GO_REF:0000107 NCBI chr 3:84,060,417...84,286,008
Ensembl chr 3:84,064,440...84,286,360
JBrowse link
G RPS19 ribosomal protein S19 IEA Ensembl GO_REF:0000107 NCBI chr 1:112,418,800...112,427,445
Ensembl chr 1:112,411,281...112,427,381
JBrowse link
G SP3 Sp3 transcription factor IEA Ensembl GO_REF:0000107 NCBI chr36:18,023,750...18,086,995
Ensembl chr36:18,024,627...18,077,587
JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 IEA Ensembl GO_REF:0000107 NCBI chr18:49,784,480...49,794,361
Ensembl chr18:49,784,490...49,794,317
JBrowse link
G TPD52 tumor protein D52 ISO (PMID:15576473) UniProtKB PMID:15576473 NCBI chr29:27,418,239...27,524,919
Ensembl chr29:27,419,736...27,525,336
JBrowse link
G TSHR thyroid stimulating hormone receptor IEA Ensembl GO_REF:0000107 NCBI chr 8:53,327,280...53,482,898
Ensembl chr 8:53,326,655...53,482,898
JBrowse link
G URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr25:11,682,304...11,693,143
Ensembl chr25:11,581,206...11,692,284
JBrowse link
G YY1 YY1 transcription factor ISO (MGI:MGI:5484711|PMID:23531880) MGI PMID:23531880 MGI:MGI:5484711 NCBI chr 8:68,539,511...68,572,796
Ensembl chr 8:68,539,353...68,568,058
JBrowse link
G ZBTB1 zinc finger and BTB domain containing 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:38,933,721...38,959,306
Ensembl chr 8:38,933,805...38,959,306
JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A IEA Ensembl GO_REF:0000107 NCBI chr20:55,517,531...55,527,071
Ensembl chr20:55,505,916...55,523,736
JBrowse link
G ZC3H7B zinc finger CCCH-type containing 7B ISO (MGI:MGI:3812266|PMID:18684867) MGI PMID:18684867 MGI:MGI:3812266 NCBI chr10:23,882,379...23,944,850
Ensembl chr10:23,884,981...23,920,131
JBrowse link
B cell affinity maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562
JBrowse link
G LOC100856137 HLA class II histocompatibility antigen, DQ beta 2 chain IEA Ensembl GO_REF:0000107 NCBI chr12:2,244,820...2,250,822
Ensembl chr12:2,244,820...2,251,662
JBrowse link
B cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator IEA Ensembl GO_REF:0000107 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit IEA Ensembl GO_REF:0000107 NCBI chr29:24,904...243,926
Ensembl chr29:35,007...243,895
JBrowse link
G RAG2 recombination activating 2 IEA Ensembl GO_REF:0000107 NCBI chr18:31,614,143...31,621,489
Ensembl chr18:31,618,481...31,620,064
JBrowse link
G TCF3 transcription factor 3 ISO (PMID:15030778) UniProtKB PMID:15030778 NCBI chr20:57,255,091...57,284,223
Ensembl chr20:57,254,384...57,283,981
JBrowse link
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
B cell negative selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 IEA Ensembl GO_REF:0000107 NCBI chr12:2,950,359...2,957,604
Ensembl chr12:2,948,364...2,957,018
JBrowse link
G BAX BCL2 associated X, apoptosis regulator IEA Ensembl GO_REF:0000107 NCBI chr 1:107,423,388...107,426,464
Ensembl chr 1:107,422,424...107,426,464
JBrowse link
B-1 B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD19 CD19 molecule IEA Ensembl GO_REF:0000107 NCBI chr 6:18,419,092...18,425,524
Ensembl chr 6:18,418,241...18,425,400
JBrowse link
G MALT1 MALT1 paracaspase IEA Ensembl GO_REF:0000107 NCBI chr 1:17,351,458...17,412,591
Ensembl chr 1:17,354,926...17,403,927
JBrowse link
B-1 B cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLAMF8 SLAM family member 8 ISO (MGI:MGI:6215454|PMID:11313408) UniProt PMID:11313408 MGI:MGI:6215454 NCBI chr38:22,299,455...22,307,090
Ensembl chr38:22,300,128...22,307,096
JBrowse link
B-1a B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMTM7 CKLF like MARVEL transmembrane domain containing 7 IEA Ensembl GO_REF:0000107 NCBI chr23:12,317,636...12,382,836
Ensembl chr23:12,328,303...12,382,837
JBrowse link
G NFATC1 nuclear factor of activated T cells 1 ISO (MGI:MGI:2680742|PMID:14595020) MGI PMID:14595020 MGI:MGI:2680742 NCBI chr 1:1,027,021...1,121,362
Ensembl chr 1:1,028,695...1,121,588
JBrowse link
G PLCL2 phospholipase C like 2 IEA Ensembl GO_REF:0000107 NCBI chr23:25,814,392...25,999,666
Ensembl chr23:25,814,862...25,999,749
JBrowse link
follicular B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLCG2 phospholipase C gamma 2 IEA Ensembl GO_REF:0000107 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049
JBrowse link
germinal center B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IEA Ensembl GO_REF:0000107 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160
JBrowse link
G CDH17 cadherin 17 IEA Ensembl GO_REF:0000107 NCBI chr29:38,918,098...38,980,709
Ensembl chr29:38,918,574...38,977,217
JBrowse link
G IL21 interleukin 21 ISS UniProt GO_REF:0000024 NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266
JBrowse link
G IL6 interleukin 6 ISO (MGI:MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:MGI:5450752 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G ITFG2 integrin alpha FG-GAP repeat containing 2 IEA Ensembl GO_REF:0000107 NCBI chr27:41,933,741...41,944,464
Ensembl chr27:41,934,575...41,944,472
JBrowse link
G POU2AF1 POU class 2 homeobox associating factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:21,671,000...21,695,757
Ensembl chr 5:21,628,439...21,694,773
JBrowse link
immature B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FNIP1 folliculin interacting protein 1 ISS UniProtKB GO_REF:0000024 NCBI chr11:19,979,294...20,134,341
Ensembl chr11:19,979,163...20,134,229
JBrowse link
G IRF2BP2 interferon regulatory factor 2 binding protein 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:5,242,225...5,249,371
Ensembl chr 4:5,244,869...5,247,247
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISS UniProtKB GO_REF:0000024 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029
JBrowse link
G SYVN1 synoviolin 1 ISO (MGI:MGI:6220623|PMID:29907570) UniProt PMID:29907570 MGI:MGI:6220623 NCBI chr18:52,061,284...52,068,672
Ensembl chr18:52,060,347...52,067,582
JBrowse link
marginal zone B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL3 BCL3 transcription coactivator ISO (MGI:MGI:85481|PMID:9009202) MGI PMID:9009202 MGI:MGI:85481 NCBI chr 1:110,620,850...110,628,830
Ensembl chr 1:110,620,827...110,654,771
JBrowse link
G CDH17 cadherin 17 IEA Ensembl GO_REF:0000107 NCBI chr29:38,918,098...38,980,709
Ensembl chr29:38,918,574...38,977,217
JBrowse link
G DLL1 delta like canonical Notch ligand 1 IEA Ensembl GO_REF:0000107 NCBI chr12:72,265,078...72,272,347
Ensembl chr12:72,265,682...72,272,348
JBrowse link
G DOCK10 dedicator of cytokinesis 10 ISO (MGI:MGI:5818419|PMID:25729399) UniProtKB PMID:25729399 MGI:MGI:5818419 NCBI chr25:37,962,666...38,161,396
Ensembl chr25:37,963,297...38,161,305
JBrowse link
G DOCK11 dedicator of cytokinesis 11 IEA Ensembl GO_REF:0000107 NCBI chr  X:90,752,726...90,892,931
Ensembl chr  X:90,716,197...90,892,062
JBrowse link
G LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase IEA Ensembl GO_REF:0000107 NCBI chr 6:14,631,638...14,640,147
Ensembl chr 6:14,632,691...14,635,485
JBrowse link
G MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase IEA Ensembl GO_REF:0000107 NCBI chr10:27,082,616...27,098,994
Ensembl chr10:27,082,789...27,098,617
JBrowse link
G NOTCH2 notch receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857
JBrowse link
G PTK2B protein tyrosine kinase 2 beta IEA Ensembl GO_REF:0000107 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133
JBrowse link
mature B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU2F2 POU class 2 homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:112,165,908...112,252,712
Ensembl chr 1:112,220,511...112,321,672
JBrowse link
mature B cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C9H17orf99 chromosome 9 C17orf99 homolog ISO (MGI:MGI:6103709|PMID:28978694) UniProtKB PMID:28978694 MGI:MGI:6103709 NCBI chr 9:2,977,401...2,987,450
Ensembl chr 9:2,976,893...2,987,564
JBrowse link
G GPR183 G protein-coupled receptor 183 IEA Ensembl GO_REF:0000107 NCBI chr22:49,332,665...49,347,721
Ensembl chr22:49,333,188...49,347,593
JBrowse link
memory B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 ISO (MGI:MGI:2387354|PMID:10755614) UniProt PMID:10755614 MGI:MGI:2387354 NCBI chr13:29,853,182...29,949,004
Ensembl chr13:29,846,834...29,872,918
JBrowse link
negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT3 fms related receptor tyrosine kinase 3 ISO (MGI:MGI:3623701|PMID:16618805) MGI PMID:16618805 MGI:MGI:3623701 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284
JBrowse link
G HMGB3 high mobility group box 3 IEA Ensembl GO_REF:0000107 NCBI chr  X:119,152,166...119,159,803
Ensembl chr  X:119,155,786...119,159,814
JBrowse link
G ID2 inhibitor of DNA binding 2 ISO (MGI:MGI:3805135|PMID:18523151) MGI PMID:18523151 MGI:MGI:3805135 NCBI chr10:54,954,852...54,957,116 JBrowse link
G SFRP1 secreted frizzled related protein 1 ISO (MGI:MGI:3814493|PMID:18941195)
(PMID:18941195)
UniProtKB PMID:18941195 MGI:MGI:3814493 NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964
JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CR1L complement C3b/C4b receptor 1 like ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr 7:6,484,281...6,549,677 JBrowse link
plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LGALS1 galectin 1 ISO (MGI:MGI:5301217|PMID:21753146) MGI PMID:21753146 MGI:MGI:5301217 NCBI chr10:26,932,351...26,935,580
Ensembl chr10:26,932,301...26,935,646
JBrowse link
G LGALS8 galectin 8 ISO (MGI:MGI:5301217|PMID:21753146) MGI PMID:21753146 MGI:MGI:5301217 NCBI chr 4:3,548,066...3,581,382
Ensembl chr 4:3,533,200...3,567,311
JBrowse link
G NKX2-3 NK2 homeobox 3 IEA Ensembl GO_REF:0000107 NCBI chr28:12,466,319...12,469,467
Ensembl chr28:12,466,368...12,469,473
JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP11C ATPase phospholipid transporting 11C IEA Ensembl GO_REF:0000107 NCBI chr  X:109,695,018...109,888,284
Ensembl chr  X:109,697,086...109,880,624
JBrowse link
G BAD BCL2 associated agonist of cell death IEA Ensembl GO_REF:0000107 NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405
JBrowse link
G CD27 CD27 molecule IEA InterPro GO_REF:0000002 NCBI chr27:38,534,704...38,537,806
Ensembl chr27:38,534,707...38,537,604
JBrowse link
G IL2RG interleukin 2 receptor subunit gamma ISO (MGI:MGI:1095961|PMID:9252128) MGI PMID:9252128 MGI:MGI:1095961 NCBI chr  X:55,480,846...55,488,485
Ensembl chr  X:55,481,092...55,484,751
JBrowse link
G IL7 interleukin 7 IEA Ensembl GO_REF:0000107 NCBI chr29:26,384,493...26,422,586
Ensembl chr29:26,384,493...26,422,737
JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D IEA Ensembl GO_REF:0000107 NCBI chr25:44,612,146...44,731,347
Ensembl chr25:44,611,523...44,730,200
JBrowse link
G MMP14 matrix metallopeptidase 14 IEA Ensembl GO_REF:0000107 NCBI chr 8:3,183,419...3,193,079
Ensembl chr 8:3,183,606...3,194,122
JBrowse link
G NCKAP1L NCK associated protein 1 like IEA Ensembl GO_REF:0000107 NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439
JBrowse link
G PCID2 PCI domain containing 2 IEA Ensembl GO_REF:0000107 NCBI chr22:60,602,440...60,623,811
Ensembl chr22:60,602,888...60,623,719
JBrowse link
G PPP2R3C protein phosphatase 2 regulatory subunit B''gamma IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:13,863,017...13,885,245
Ensembl chr 8:13,863,380...13,885,130
JBrowse link
G PRDM1 PR/SET domain 1 NOT ISO (MGI:MGI:3826899|PMID:18845144) MGI PMID:18845144 MGI:MGI:3826899 NCBI chr12:63,454,242...63,495,278
Ensembl chr12:63,470,974...63,495,579
JBrowse link
G STAT5A signal transducer and activator of transcription 5A ISO (MGI:MGI:1889695|PMID:10979977) MGI PMID:10979977 MGI:MGI:1889695 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103
JBrowse link
G STAT5B signal transducer and activator of transcription 5B IEA Ensembl GO_REF:0000107 NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485
JBrowse link
G SYK spleen associated tyrosine kinase IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583
JBrowse link
G XBP1 X-box binding protein 1 ISO (PMID:11460154) UniProtKB PMID:11460154 NCBI chr26:22,162,675...22,168,149 JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057
JBrowse link
G IL2 interleukin 2 ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394
JBrowse link
G XBP1 X-box binding protein 1 ISO (PMID:11460154) UniProtKB PMID:11460154 NCBI chr26:22,162,675...22,168,149 JBrowse link
pre-B cell allelic exclusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase IEA Ensembl GO_REF:0000107 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G RAG1 recombination activating 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:31,628,231...31,639,980
Ensembl chr18:31,630,737...31,641,660
JBrowse link
G RAG2 recombination activating 2 IEA Ensembl GO_REF:0000107 NCBI chr18:31,614,143...31,621,489
Ensembl chr18:31,618,481...31,620,064
JBrowse link
pre-B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP11C ATPase phospholipid transporting 11C IEA Ensembl GO_REF:0000107 NCBI chr  X:109,695,018...109,888,284
Ensembl chr  X:109,697,086...109,880,624
JBrowse link
G FOXP1 forkhead box P1 IEA Ensembl GO_REF:0000107 NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397
JBrowse link
G MIR17 microRNA mir-17 ISO (MGI:MGI:3789916|PMID:18329372) MGI PMID:18329372 MGI:MGI:3789916 NCBI chr22:42,478,013...42,478,071
Ensembl chr22:42,478,000...42,478,083
JBrowse link
G MIR18A microRNA mir-18a ISO (MGI:MGI:3789916|PMID:18329372) MGI PMID:18329372 MGI:MGI:3789916 NCBI chr22:42,478,138...42,478,229
Ensembl chr22:42,478,138...42,478,229
JBrowse link
G MIR19A microRNA mir-19a ISO (MGI:MGI:3789916|PMID:18329372) MGI PMID:18329372 MGI:MGI:3789916 NCBI chr22:42,478,298...42,478,355
Ensembl chr22:42,478,285...42,478,366
JBrowse link
G MIR19B-1 microRNA mir-19b-1 ISO (MGI:MGI:3789916|PMID:18329372) MGI PMID:18329372 MGI:MGI:3789916 NCBI chr22:42,478,598...42,478,656 JBrowse link
G MIR20A microRNA mir-20a ISO (MGI:MGI:3789916|PMID:18329372) MGI PMID:18329372 MGI:MGI:3789916 NCBI chr22:42,478,462...42,478,520
Ensembl chr22:42,478,462...42,478,520
JBrowse link
G MIR92A-1 microRNA mir-92a-1 ISO (MGI:MGI:3789916|PMID:18329372) MGI PMID:18329372 MGI:MGI:3789916 NCBI chr22:42,478,714...42,478,772 JBrowse link
regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKLE1 ankyrin repeat and LEM domain containing 1 NOT ISO (MGI:MGI:5800654|PMID:27010503) UniProtKB PMID:27010503 MGI:MGI:5800654 NCBI chr20:45,461,135...45,465,922
Ensembl chr20:45,461,676...45,465,417
JBrowse link
G CARD11 caspase recruitment domain family member 11 IEA Ensembl GO_REF:0000107 NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094
JBrowse link
G CYLD CYLD lysine 63 deubiquitinase IEA Ensembl GO_REF:0000107 NCBI chr 2:64,561,684...64,628,829
Ensembl chr 2:64,562,503...64,628,175
JBrowse link
G IKZF3 IKAROS family zinc finger 3 IEA Ensembl GO_REF:0000107 NCBI chr 9:22,643,482...22,733,988
Ensembl chr 9:22,643,640...22,728,385
JBrowse link
G MIR150 microRNA mir-150 ISO (MGI:MGI:3763573|PMID:17927961) MGI PMID:17927961 MGI:MGI:3763573 NCBI chr 1:106,998,756...106,998,812
Ensembl chr 1:106,998,756...106,998,812
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 IEA InterPro GO_REF:0000002 NCBI chr10:23,008,084...23,047,227
Ensembl chr10:23,008,393...23,045,565
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 IEA Ensembl GO_REF:0000107 NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937
JBrowse link
G SLAMF8 SLAM family member 8 ISO (MGI:MGI:6215454|PMID:11313408) UniProt PMID:11313408 MGI:MGI:6215454 NCBI chr38:22,299,455...22,307,090
Ensembl chr38:22,300,128...22,307,096
JBrowse link
G TLR9 toll like receptor 9 ISS UniProtKB GO_REF:0000024 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:42,663,287...42,668,665
Ensembl chr 8:42,664,223...42,668,514
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 IEA Ensembl GO_REF:0000107 NCBI chr10:45,746,952...45,751,268
Ensembl chr10:45,748,936...45,751,250
JBrowse link
transitional one stage B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16187
    immune system process 2294
      leukocyte activation 885
        lymphocyte activation 716
          lymphocyte differentiation 389
            B cell differentiation 136
              B cell lineage commitment + 6
              B cell selection + 4
              immature B cell differentiation + 16
              mature B cell differentiation + 32
              negative regulation of B cell differentiation + 5
              positive regulation of B cell differentiation + 17
              regulation of B cell differentiation + 33
Path 2
Term Annotations click to browse term
  biological_process 16187
    developmental process 6309
      anatomical structure development 5857
        multicellular organism development 5350
          system development 4984
            immune system development 1024
              hematopoietic or lymphoid organ development 961
                hemopoiesis 914
                  leukocyte differentiation 575
                    lymphocyte differentiation 389
                      B cell differentiation 136
                        B cell lineage commitment + 6
                        B cell selection + 4
                        immature B cell differentiation + 16
                        mature B cell differentiation + 32
                        negative regulation of B cell differentiation + 5
                        positive regulation of B cell differentiation + 17
                        regulation of B cell differentiation + 33
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.