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ONTOLOGY REPORT - ANNOTATIONS


Term:B cell differentiation
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Accession:GO:0030183 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: B lymphocyte differentiation
 related_synonym: B cell development
 alt_id: GO:0042115


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B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 ISO (MGI:MGI:3828349|PMID:17371977) BHF-UCL PMID:17371977 MGI:MGI:3828349 NCBI chr 3:126,795,513...126,853,995
Ensembl chr 3:126,795,426...126,853,995
JBrowse link
G ADGRG3 adhesion G protein-coupled receptor G3 IEA Ensembl GO_REF:0000107 NCBI chr 6:19,573,080...19,599,082
Ensembl chr 6:19,574,514...19,599,082
JBrowse link
G BCL11A BAF chromatin remodeling complex subunit BCL11A ISO (MGI:MGI:2662805|PMID:12717432) MGI PMID:12717432 MGI:MGI:2662805 NCBI chr 3:81,195,217...81,296,165
Ensembl chr 3:81,196,294...81,296,165
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO (MGI:MGI:2156164|PMID:8170972), (MGI:MGI:85476|PMID:9028316) MGI PMID:8170972, PMID:9028316 MGI:MGI:2156164, MGI:MGI:85476 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,288,544...158,518,879
JBrowse link
G BCL6 BCL6 transcription repressor IEA Ensembl GO_REF:0000107 NCBI chr13:125,377,247...125,401,328
Ensembl chr13:125,377,248...125,393,330
JBrowse link
G CARD11 caspase recruitment domain family member 11 IEA Ensembl GO_REF:0000107 NCBI chr 3:2,145,178...2,266,377
Ensembl chr 3:2,145,177...2,266,356
JBrowse link
G CD40LG CD40 ligand IEA Ensembl GO_REF:0000107 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,711
JBrowse link
G CD79A CD79a molecule IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 6:49,996,116...49,999,294
Ensembl chr 6:49,975,957...50,010,059
JBrowse link
G CD79B CD79b molecule IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:15,052,966...15,056,441
Ensembl chr12:15,053,007...15,056,441
JBrowse link
G CDH17 cadherin 17 ISO (MGI:MGI:3531365|PMID:15688343) UniProtKB PMID:15688343 MGI:MGI:3531365 NCBI chr 4:42,508,852...42,597,888
Ensembl chr 4:42,515,276...42,597,772
JBrowse link
G CEBPG CCAAT enhancer binding protein gamma IEA Ensembl GO_REF:0000107 NCBI chr 6:43,164,902...43,175,002
Ensembl chr 6:43,164,918...43,175,002
JBrowse link
G CLCF1 cardiotrophin like cytokine factor 1 ISO (MGI:MGI:1346205|PMID:10500198) MGI PMID:10500198 MGI:MGI:1346205 NCBI chr 2:5,142,315...5,152,750 JBrowse link
G DCAF1 DDB1 and CUL4 associated factor 1 IEA Ensembl GO_REF:0000107 NCBI chr13:33,670,976...33,750,872
Ensembl chr13:33,670,974...33,750,734
JBrowse link
G DCLRE1C DNA cross-link repair 1C IEA Ensembl GO_REF:0000107 NCBI chr10:46,820,016...46,863,848
Ensembl chr10:46,820,051...46,868,030
JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 IEA Ensembl GO_REF:0000107 NCBI chr18:36,578,928...36,584,211
Ensembl chr18:36,549,544...36,584,130
JBrowse link
G EP300 E1A binding protein p300 IEA Ensembl GO_REF:0000107 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO (MGI:MGI:5484711|PMID:23531880) MGI PMID:23531880 MGI:MGI:5484711 NCBI chr 9:109,384,976...109,450,943
Ensembl chr 9:109,384,995...109,450,941
JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ISO (MGI:MGI:4946600|PMID:21228325) UniProtKB PMID:21228325 MGI:MGI:4946600 NCBI chr11:5,370,475...5,455,439
Ensembl chr11:5,361,788...5,455,359
JBrowse link
G FZD9 frizzled class receptor 9 IEA Ensembl GO_REF:0000107 NCBI chr 3:10,753,294...10,762,812
Ensembl chr 3:10,754,783...10,757,147
JBrowse link
G GON4L gon-4 like IEA InterPro GO_REF:0000002 NCBI chr 4:94,161,887...94,248,785 JBrowse link
G GPS2 G protein pathway suppressor 2 IEA Ensembl GO_REF:0000107 NCBI chr12:52,664,869...52,667,643
Ensembl chr12:52,664,873...52,667,610
JBrowse link
G HHEX hematopoietically expressed homeobox ISO (MGI:MGI:2449266|PMID:12522149) MGI PMID:12522149 MGI:MGI:2449266 NCBI chr14:104,194,424...104,199,684
Ensembl chr14:104,194,343...104,200,221
JBrowse link
G IFN-ALPHA-15 interferon-alpha-15 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,694,271...201,694,837
Ensembl chr 1:201,677,540...201,695,829
JBrowse link
G IFN-ALPHA-4 interferon-alpha-4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,616,020...201,616,589
Ensembl chr 1:201,615,970...201,616,649
JBrowse link
G IFN-ALPHA-9 interferon-alpha-9 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,407,647...201,408,216
Ensembl chr 1:201,407,587...201,408,266
JBrowse link
G IFN-ALPHAOMEGA interferon-alphaomega IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,831,741...201,832,298
Ensembl chr 1:201,831,741...201,832,298
JBrowse link
G IFN-DELTA-2 interferon-delta-2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,495,440...201,496,375
Ensembl chr 1:201,654,500...201,655,595
JBrowse link
G IFN-DELTA-5 interferon-delta-5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,412,274...201,412,828
Ensembl chr 1:201,412,274...201,412,828
JBrowse link
G IFN-DELTA-6 interferon-delta-6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,342,788...201,343,342
Ensembl chr 1:201,342,788...201,343,342
JBrowse link
G IFN-DELTA-8 interferon-delta-8 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,277,798...201,278,301
Ensembl chr 1:201,273,679...201,280,086
JBrowse link
G IFN-DELTA-9 interferon-delta-9 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,673,749...201,674,303
Ensembl chr 1:201,673,749...201,674,303
JBrowse link
G IFN-OMEGA-2 interferon-omega-2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,623,473...201,624,003
Ensembl chr 1:201,623,473...201,624,003
JBrowse link
G IFN-OMEGA-4 interferon omega 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,334,366...201,334,938
Ensembl chr 1:201,334,366...201,334,938
JBrowse link
G IFN-OMEGA-5 interferon omega 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,781,339...201,781,911
Ensembl chr 1:201,781,339...201,781,911
JBrowse link
G IFN-OMEGA-6 interferon omega 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,715,465...201,716,037
Ensembl chr 1:201,713,376...201,720,068
JBrowse link
G IFN-OMEGA-7 interferon omega 7 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,316,989...201,317,561
Ensembl chr 1:201,316,989...201,317,561
JBrowse link
G IFNA1 interferon, alpha 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,515,835...201,516,477
Ensembl chr 1:201,736,694...201,750,298
JBrowse link
G IFNB1 interferon beta 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,850,935...201,851,495
Ensembl chr 1:201,850,935...201,851,495
JBrowse link
G IFNE interferon epsilon IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,219,848...201,228,361
Ensembl chr 1:201,221,665...201,227,047
JBrowse link
G IFNK interferon kappa IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:38,444,720...38,445,346
Ensembl chr10:38,444,720...38,445,346
JBrowse link
G IKZF1 IKAROS family zinc finger 1 ISO (MGI:MGI:5449477|PMID:23071339)
(MGI:MGI:68746|PMID:7923373)
MGI PMID:7923373, PMID:23071339 MGI:MGI:5449477, MGI:MGI:68746 NCBI chr 9:136,372,202...136,464,942
Ensembl chr 9:136,372,724...136,464,942
JBrowse link
G JAK3 Janus kinase 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:59,905,901...59,926,504
Ensembl chr 2:59,905,919...59,926,495
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:41,402,334...41,492,306
Ensembl chr 8:41,402,043...41,493,735
JBrowse link
G LOC100155760 interferon omega 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:201,246,072...201,246,611 JBrowse link
G LOC100519177 GTPase IMAP family member 1 ISO (MGI:MGI:4455099|PMID:20194894) MGI PMID:20194894 MGI:MGI:4455099 NCBI chr18:6,457,532...6,462,776 JBrowse link
G LYL1 LYL1 basic helix-loop-helix family member IEA Ensembl GO_REF:0000107 NCBI chr 2:65,950,608...65,956,423
Ensembl chr 2:65,952,519...65,955,017
JBrowse link
G MS4A1 membrane spanning 4-domains A1 ISO (PMID:3925015) UniProt PMID:3925015 NCBI chr 2:11,216,238...11,229,060 JBrowse link
G MSH2 mutS homolog 2 IEA Ensembl GO_REF:0000107 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,628
JBrowse link
G MYB MYB proto-oncogene, transcription factor ISO (MGI:MGI:3763573|PMID:17927961) MGI PMID:17927961 MGI:MGI:3763573 NCBI chr 1:28,819,500...28,856,222
Ensembl chr 1:28,819,503...28,857,000
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 ISO (MGI:MGI:3044463|PMID:15143214) HGNC PMID:15143214 MGI:MGI:3044463 NCBI chr 5:6,296,921...6,333,371
Ensembl chr 5:6,298,573...6,336,731
JBrowse link
G NHEJ1 non-homologous end joining factor 1 IEA Ensembl GO_REF:0000107 NCBI chr15:121,100,624...121,190,086
Ensembl chr15:121,100,611...121,190,062
JBrowse link
G NKX2-3 NK2 homeobox 3 ISO (MGI:MGI:2654966|PMID:12682228) MGI PMID:12682228 MGI:MGI:2654966 NCBI chr14:110,720,384...110,724,002
Ensembl chr14:110,720,397...110,724,001
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 4:93,219,509...93,237,944
Ensembl chr 4:93,219,516...93,237,930
JBrowse link
G ONECUT1 one cut homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:118,913,400...118,958,140
Ensembl chr 1:118,913,785...118,954,614
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,434,873...46,523,609
JBrowse link
G PLCG2 phospholipase C gamma 2 ISO (MGI:MGI:1861532|PMID:10925250) UniProtKB PMID:10925250 MGI:MGI:1861532 NCBI chr 6:6,433,146...6,603,092
Ensembl chr 6:6,433,153...6,603,060
JBrowse link
G POLM DNA polymerase mu IEA Ensembl GO_REF:0000107 NCBI chr18:51,077,845...51,091,354 JBrowse link
G POU1F1 POU class 1 homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr13:168,510,671...168,530,394
Ensembl chr13:168,510,774...168,529,345
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:96,769,862...96,847,136
Ensembl chr 6:96,770,251...96,847,133
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C IEA Ensembl GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,466,373...21,764,560
JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J ISO (MGI:MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:MGI:3774343 NCBI chr 2:14,548,489...14,724,823
Ensembl chr 2:14,548,425...14,726,715
JBrowse link
G RABL3 RAB, member of RAS oncogene family like 3 IEA Ensembl GO_REF:0000107 NCBI chr13:139,609,164...139,653,951
Ensembl chr13:139,603,454...139,655,577
JBrowse link
G RAG1 recombination activating 1 ISS UniProt GO_REF:0000024 NCBI chr 2:24,565,447...24,573,853
Ensembl chr 2:24,565,449...24,602,590
JBrowse link
G RAG2 recombination activating 2 ISO (MGI:MGI:50458|PMID:1547488), (MGI:MGI:50459|PMID:1547487)
(MGI:MGI:2179579|PMID:11980719), (MGI:MGI:3709144|PMID:14595002)
UniProtKB
MGI
PMID:1547487, PMID:1547488, PMID:11980719, PMID:14595002 MGI:MGI:2179579, MGI:MGI:3709144, MGI:MGI:50458, MGI:MGI:50459 NCBI chr 2:24,547,605...24,553,944
Ensembl chr 2:24,546,958...24,558,430
JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region IEA Ensembl GO_REF:0000107 NCBI chr 8:19,933,035...20,166,746
Ensembl chr 8:19,922,779...20,166,755
JBrowse link
G SP3 Sp3 transcription factor IEA Ensembl GO_REF:0000107 NCBI chr15:79,935,986...79,990,139
Ensembl chr15:79,935,994...80,025,850
JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 IEA Ensembl GO_REF:0000107 NCBI chr 2:4,844,627...4,860,562
Ensembl chr 2:4,844,630...4,867,215
JBrowse link
G TPD52 tumor protein D52 ISO (PMID:15576473) UniProtKB PMID:15576473 NCBI chr 4:56,472,992...56,603,616
Ensembl chr 4:56,471,804...56,603,617
JBrowse link
G TSHR thyroid stimulating hormone receptor IEA Ensembl GO_REF:0000107 NCBI chr 7:103,768,260...103,925,777
Ensembl chr 7:103,768,296...103,925,922
JBrowse link
G YY1 YY1 transcription factor ISO (MGI:MGI:5484711|PMID:23531880) MGI PMID:23531880 MGI:MGI:5484711 NCBI chr 7:121,132,168...121,170,699
Ensembl chr 7:121,131,917...121,170,697
JBrowse link
G ZBTB1 zinc finger and BTB domain containing 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:88,575,563...88,602,726
Ensembl chr 7:88,576,008...88,610,480
JBrowse link
G ZBTB7A zinc finger and BTB domain containing 7A IEA Ensembl GO_REF:0000107 NCBI chr 2:74,678,293...74,699,347
Ensembl chr 2:74,681,192...74,695,975
JBrowse link
B cell affinity maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTK Bruton tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr  X:82,981,512...83,014,475
Ensembl chr  X:82,981,515...83,014,573
JBrowse link
G SLA-DQB1 SLA-DQ beta1 domain IEA Ensembl GO_REF:0000107 NCBI chr 7:24,969,034...24,977,238
Ensembl chr 7:24,943,107...24,977,297
JBrowse link
B cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator ISO (MGI:MGI:78866|PMID:8788039) MGI PMID:8788039 MGI:MGI:78866 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,288,544...158,518,879
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit IEA Ensembl GO_REF:0000107 NCBI chr 4:79,687,375...79,850,146
Ensembl chr 4:79,687,359...79,847,281
JBrowse link
G RAG2 recombination activating 2 IEA Ensembl GO_REF:0000107 NCBI chr 2:24,547,605...24,553,944
Ensembl chr 2:24,546,958...24,558,430
JBrowse link
G TCF3 transcription factor 3 ISO (PMID:15030778) UniProtKB PMID:15030778 NCBI chr 2:76,859,079...76,906,275
Ensembl chr 2:76,858,786...76,898,351
JBrowse link
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
B cell negative selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAK1 BCL2 antagonist/killer 1 ISO (MGI:MGI:3588597|PMID:16055554) MGI PMID:16055554 MGI:MGI:3588597 NCBI chr 7:29,808,849...29,815,345 JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO (MGI:MGI:3588597|PMID:16055554) MGI PMID:16055554 MGI:MGI:3588597 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,187,260...54,228,144
JBrowse link
B-1 B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD19 CD19 molecule IEA Ensembl GO_REF:0000107 NCBI chr 3:18,592,785...18,601,273
Ensembl chr 3:18,592,879...18,603,595
JBrowse link
G MALT1 MALT1 paracaspase IEA Ensembl GO_REF:0000107 NCBI chr 1:162,076,933...162,144,915
Ensembl chr 1:162,076,951...162,144,880
JBrowse link
B-1 B cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLAMF8 SLAM family member 8 ISO (MGI:MGI:6215454|PMID:11313408) UniProt PMID:11313408 MGI:MGI:6215454 NCBI chr 4:90,661,984...90,673,044
Ensembl chr 4:90,661,985...90,673,340
JBrowse link
B-1a B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMTM7 CKLF like MARVEL transmembrane domain containing 7 IEA Ensembl GO_REF:0000107 NCBI chr13:18,371,327...18,424,132
Ensembl chr13:18,372,194...18,426,964
JBrowse link
G NFATC1 nuclear factor of activated T cells 1 ISO (MGI:MGI:2680742|PMID:14595020) MGI PMID:14595020 MGI:MGI:2680742 NCBI chr 1:145,940,099...146,002,897
Ensembl chr 1:145,911,045...146,017,701
JBrowse link
G PLCL2 phospholipase C like 2 IEA Ensembl GO_REF:0000107 NCBI chr13:3,992,230...4,201,574
Ensembl chr13:3,992,835...4,201,569
JBrowse link
follicular B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLCG2 phospholipase C gamma 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:6,433,146...6,603,092
Ensembl chr 6:6,433,153...6,603,060
JBrowse link
germinal center B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IEA Ensembl GO_REF:0000107 NCBI chr17:47,044,492...47,072,232
Ensembl chr17:47,044,495...47,072,245
JBrowse link
G CDH17 cadherin 17 IEA Ensembl GO_REF:0000107 NCBI chr 4:42,508,852...42,597,888
Ensembl chr 4:42,515,276...42,597,772
JBrowse link
G IL21 interleukin 21 ISS UniProt GO_REF:0000024 NCBI chr 8:101,532,742...101,540,712
Ensembl chr 8:101,530,949...101,540,738
JBrowse link
G IL6 interleukin 6 ISO (MGI:MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:MGI:5450752 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G ITFG2 integrin alpha FG-GAP repeat containing 2 IEA Ensembl GO_REF:0000107 NCBI chr 5:67,292,901...67,306,208
Ensembl chr 5:67,291,771...67,305,758
JBrowse link
G POU2AF1 POU class 2 homeobox associating factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:39,121,422...39,144,636
Ensembl chr 9:39,119,012...39,144,606
JBrowse link
immature B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FNIP1 folliculin interacting protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:133,958,112...134,093,408
Ensembl chr 2:133,958,114...134,093,413
JBrowse link
G IRF2BP2 interferon regulatory factor 2 binding protein 2 IEA Ensembl GO_REF:0000107 NCBI chr14:56,545,792...56,551,131
Ensembl chr14:56,545,189...56,551,125
JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISS
IEA
UniProt
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 8:41,402,334...41,492,306
Ensembl chr 8:41,402,043...41,493,735
JBrowse link
G SYVN1 synoviolin 1 ISO (MGI:MGI:6220623|PMID:29907570) UniProt PMID:29907570 MGI:MGI:6220623 NCBI chr 2:7,059,444...7,066,617
Ensembl chr 2:7,059,462...7,072,809
JBrowse link
marginal zone B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL3 BCL3 transcription coactivator ISO (MGI:MGI:85481|PMID:9009202) MGI PMID:9009202 MGI:MGI:85481 NCBI chr 6:51,256,033...51,264,923
Ensembl chr 6:51,256,033...51,265,355
JBrowse link
G CDH17 cadherin 17 IEA Ensembl GO_REF:0000107 NCBI chr 4:42,508,852...42,597,888
Ensembl chr 4:42,515,276...42,597,772
JBrowse link
G DLL1 delta like canonical Notch ligand 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:198,815...211,346
Ensembl chr 1:199,231...211,344
JBrowse link
G DOCK10 dedicator of cytokinesis 10 ISO (MGI:MGI:5818419|PMID:25729399) UniProtKB PMID:25729399 MGI:MGI:5818419 NCBI chr15:126,435,577...126,711,755
Ensembl chr15:126,435,267...126,711,531
JBrowse link
G DOCK11 dedicator of cytokinesis 11 IEA Ensembl GO_REF:0000107 NCBI chr  X:97,068,488...97,267,528
Ensembl chr  X:97,068,355...97,267,517
JBrowse link
G LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase IEA Ensembl GO_REF:0000107 NCBI chr 3:1,721,044...1,819,426
Ensembl chr 3:1,810,892...1,820,048
JBrowse link
G MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase IEA Ensembl GO_REF:0000107 NCBI chr 5:10,319,821...10,334,500
Ensembl chr 5:10,319,814...10,344,833
JBrowse link
G NOTCH2 notch receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:100,951,522...101,152,348
Ensembl chr 4:100,951,507...101,150,198
JBrowse link
G PTK2B protein tyrosine kinase 2 beta IEA Ensembl GO_REF:0000107 NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,194
JBrowse link
mature B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POU2F2 POU class 2 homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:49,791,937...49,829,771
Ensembl chr 6:49,710,999...49,827,560
JBrowse link
mature B cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR183 G protein-coupled receptor 183 IEA Ensembl GO_REF:0000107 NCBI chr11:68,231,851...68,248,627
Ensembl chr11:68,231,851...68,245,751
JBrowse link
memory B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 ISO (MGI:MGI:2387354|PMID:10755614) UniProt PMID:10755614 MGI:MGI:2387354 NCBI chr 4:7,814,492...7,911,053
Ensembl chr 4:7,814,694...7,909,528
JBrowse link
negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT3 fms related receptor tyrosine kinase 3 ISO (MGI:MGI:3623701|PMID:16618805) MGI PMID:16618805 MGI:MGI:3623701 NCBI chr11:5,370,475...5,455,439
Ensembl chr11:5,361,788...5,455,359
JBrowse link
G HMGB3 high mobility group box 3 IEA Ensembl GO_REF:0000107 NCBI chr  X:122,591,413...122,599,496
Ensembl chr  X:122,592,936...122,599,493
JBrowse link
G ID2 inhibitor of DNA binding 2 IEA Ensembl GO_REF:0000107 NCBI chr 3:127,500,759...127,503,207
Ensembl chr 3:127,500,759...127,503,257
JBrowse link
G SFRP1 secreted frizzled related protein 1 IEA Ensembl GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748
JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CR1 complement C3b/C4b receptor 1 (Knops blood group) ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr 9:68,025,673...68,132,162 JBrowse link
plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITM2A integral membrane protein 2A IEA Ensembl GO_REF:0000107 NCBI chr  X:63,430,020...63,437,027
Ensembl chr  X:63,430,021...63,437,032
JBrowse link
G LGALS1 galectin 1 ISO (MGI:MGI:5301217|PMID:21753146) MGI PMID:21753146 MGI:MGI:5301217 NCBI chr 5:10,149,069...10,152,514
Ensembl chr 5:10,149,062...10,156,210
JBrowse link
G LGALS8 galectin 8 ISO (MGI:MGI:5301217|PMID:21753146) MGI PMID:21753146 MGI:MGI:5301217 NCBI chr14:54,867,014...54,892,188
Ensembl chr14:54,867,017...54,892,049
JBrowse link
G NKX2-3 NK2 homeobox 3 IEA Ensembl GO_REF:0000107 NCBI chr14:110,720,384...110,724,002
Ensembl chr14:110,720,397...110,724,001
JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP11C ATPase phospholipid transporting 11C IEA Ensembl GO_REF:0000107 NCBI chr  X:114,394,436...114,575,658
Ensembl chr  X:114,394,438...114,582,150
JBrowse link
G BAD BCL2 associated agonist of cell death IEA Ensembl GO_REF:0000107 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863
JBrowse link
G CD27 CD27 molecule IEA InterPro GO_REF:0000002 NCBI chr 5:64,197,594...64,202,236
Ensembl chr 5:64,188,183...64,202,613
JBrowse link
G IL2RG interleukin 2 receptor subunit gamma ISO (MGI:MGI:1095961|PMID:9252128) MGI PMID:9252128 MGI:MGI:1095961 NCBI chr  X:57,143,568...57,151,242 JBrowse link
G IL7 interleukin 7 IEA Ensembl GO_REF:0000107 NCBI chr 4:57,677,895...57,744,713
Ensembl chr 4:57,685,069...57,753,797
JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D IEA Ensembl GO_REF:0000107 NCBI chr15:133,501,067...133,626,647
Ensembl chr15:133,501,092...133,626,647
JBrowse link
G MMP14 matrix metallopeptidase 14 ISS
IEA
UniProt
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,174,500...76,185,923
JBrowse link
G NCKAP1L NCK associated protein 1 like IEA Ensembl GO_REF:0000107 NCBI chr 5:19,677,613...19,720,550
Ensembl chr 5:19,677,875...19,723,132
JBrowse link
G PCID2 PCI domain containing 2 IEA Ensembl GO_REF:0000107 NCBI chr11:78,541,278...78,556,784
Ensembl chr11:78,541,318...78,556,733
JBrowse link
G PPP2R3C protein phosphatase 2 regulatory subunit B''gamma IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:64,762,863...64,789,919
Ensembl chr 7:64,763,050...64,810,973
JBrowse link
G PRDM1 PR/SET domain 1 NOT ISO (MGI:MGI:3826899|PMID:18845144) MGI PMID:18845144 MGI:MGI:3826899 NCBI chr 1:72,309,096...72,335,474
Ensembl chr 1:72,311,880...72,335,466
JBrowse link
G STAT5A signal transducer and activator of transcription 5A ISS AgBase GO_REF:0000024 NCBI chr12:20,474,221...20,498,785
Ensembl chr12:20,474,225...20,499,138
JBrowse link
G STAT5B signal transducer and activator of transcription 5B ISS
IEA
AgBase
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr12:20,498,103...20,574,365
Ensembl chr12:20,508,403...20,574,288
JBrowse link
G SYK spleen associated tyrosine kinase IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,712...2,161,172
JBrowse link
G XBP1 X-box binding protein 1 ISO (PMID:11460154) UniProtKB PMID:11460154 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,017,036
JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL2 interleukin 2 ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609
JBrowse link
G XBP1 X-box binding protein 1 IEA Ensembl GO_REF:0000107 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,017,036
JBrowse link
pre-B cell allelic exclusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase ISS
IEA
UniProt
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,658...36,759,554
JBrowse link
G RAG1 recombination activating 1 ISS
IEA
IBA
(PMID:21873635) UniProt
Ensembl
GO_Central
PMID:21873635 GO_REF:0000024, GO_REF:0000107 NCBI chr 2:24,565,447...24,573,853
Ensembl chr 2:24,565,449...24,602,590
JBrowse link
G RAG2 recombination activating 2 IEA Ensembl GO_REF:0000107 NCBI chr 2:24,547,605...24,553,944
Ensembl chr 2:24,546,958...24,558,430
JBrowse link
pre-B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP11C ATPase phospholipid transporting 11C IEA Ensembl GO_REF:0000107 NCBI chr  X:114,394,436...114,575,658
Ensembl chr  X:114,394,438...114,582,150
JBrowse link
G FOXP1 forkhead box P1 IEA Ensembl GO_REF:0000107 NCBI chr13:52,346,844...52,974,358
Ensembl chr13:52,347,849...52,974,261
JBrowse link
G LOC100519934 uncharacterized LOC100519934 ISO (MGI:MGI:2179980|PMID:9028339), (MGI:MGI:74794|PMID:7795661) MGI PMID:7795661, PMID:9028339 MGI:MGI:2179980, MGI:MGI:74794 NCBI chr 1:73,119,758...73,124,368 JBrowse link
G MIR17 microRNA mir-17 ISO (MGI:MGI:3789916|PMID:18329372) MGI PMID:18329372 MGI:MGI:3789916 NCBI chr11:60,734,656...60,734,732
Ensembl chr11:60,734,656...60,734,732
JBrowse link
G MIR18A microRNA mir-18a ISO (MGI:MGI:3789916|PMID:18329372) MGI PMID:18329372 MGI:MGI:3789916 NCBI chr11:60,734,791...60,734,882
Ensembl chr11:60,734,791...60,734,882
JBrowse link
G MIR19A microRNA mir-19a ISO (MGI:MGI:3789916|PMID:18329372) MGI PMID:18329372 MGI:MGI:3789916 NCBI chr11:60,734,939...60,735,020
Ensembl chr11:60,734,939...60,735,020
JBrowse link
G MIR19B-1 microRNA mir-19b-1 ISO (MGI:MGI:3789916|PMID:18329372) MGI PMID:18329372 MGI:MGI:3789916 NCBI chr11:60,735,238...60,735,317
Ensembl chr11:60,735,230...60,735,328
JBrowse link
G MIR20A microRNA mir-20a ISO (MGI:MGI:3789916|PMID:18329372) MGI PMID:18329372 MGI:MGI:3789916 NCBI chr11:60,735,109...60,735,179
Ensembl chr11:60,735,099...60,735,196
JBrowse link
G MIR92A-1 microRNA mir-92a-1 ISO (MGI:MGI:3789916|PMID:18329372) MGI PMID:18329372 MGI:MGI:3789916 NCBI chr11:60,735,358...60,735,437
Ensembl chr11:60,735,343...60,735,449
JBrowse link
regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKLE1 ankyrin repeat and LEM domain containing 1 NOT ISO (MGI:MGI:5800654|PMID:27010503) UniProtKB PMID:27010503 MGI:MGI:5800654 NCBI chr 2:60,391,110...60,397,559
Ensembl chr 2:60,391,111...60,396,462
JBrowse link
G CARD11 caspase recruitment domain family member 11 IEA Ensembl GO_REF:0000107 NCBI chr 3:2,145,178...2,266,377
Ensembl chr 3:2,145,177...2,266,356
JBrowse link
G CYLD CYLD lysine 63 deubiquitinase IEA Ensembl GO_REF:0000107 NCBI chr 6:34,058,091...34,121,939
Ensembl chr 6:34,059,941...34,121,272
JBrowse link
G IKZF3 IKAROS family zinc finger 3 IEA Ensembl GO_REF:0000107 NCBI chr12:22,466,386...22,562,320
Ensembl chr12:22,466,414...22,562,312
JBrowse link
G LOC100158069 Fc receptor-like protein 3 IEA Ensembl GO_REF:0000107 NCBI chr 4:92,460,744...92,506,002
Ensembl chr 4:92,460,859...92,504,038
JBrowse link
G LOC100519934 uncharacterized LOC100519934 ISO (MGI:MGI:2179980|PMID:9028339), (MGI:MGI:74794|PMID:7795661) MGI PMID:7795661, PMID:9028339 MGI:MGI:2179980, MGI:MGI:74794 NCBI chr 1:73,119,758...73,124,368 JBrowse link
G MIR150-1 microRNA mir-150-1 ISO (MGI:MGI:3763573|PMID:17927961) MGI PMID:17927961 MGI:MGI:3763573 NCBI chr 6:54,580,912...54,580,988
Ensembl chr 6:54,580,912...54,580,988
JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 IEA InterPro GO_REF:0000002 NCBI chr 5:6,296,921...6,333,371
Ensembl chr 5:6,298,573...6,336,731
JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 IEA Ensembl GO_REF:0000107 NCBI chr 5:63,762,109...63,779,086
Ensembl chr 5:63,762,112...63,808,350
JBrowse link
G SLAMF8 SLAM family member 8 ISO (MGI:MGI:6215454|PMID:11313408) UniProt PMID:11313408 MGI:MGI:6215454 NCBI chr 4:90,661,984...90,673,044
Ensembl chr 4:90,661,985...90,673,340
JBrowse link
G TLR9 toll like receptor 9 ISS UniProt GO_REF:0000024 NCBI chr13:34,353,444...34,370,990 JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:92,490,069...92,495,864
Ensembl chr 7:92,490,011...92,495,574
JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 IEA Ensembl GO_REF:0000107 NCBI chr 3:97,200,395...97,203,094
Ensembl chr 3:97,200,406...97,204,700
JBrowse link
transitional one stage B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,711
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16545
    immune system process 2305
      leukocyte activation 895
        lymphocyte activation 726
          lymphocyte differentiation 400
            B cell differentiation 147
              B cell lineage commitment + 6
              B cell selection + 4
              immature B cell differentiation + 17
              mature B cell differentiation + 32
              negative regulation of B cell differentiation + 5
              positive regulation of B cell differentiation + 17
              regulation of B cell differentiation + 35
Path 2
Term Annotations click to browse term
  biological_process 16545
    developmental process 6302
      anatomical structure development 5842
        multicellular organism development 5340
          system development 4963
            immune system development 1029
              hematopoietic or lymphoid organ development 966
                hemopoiesis 918
                  leukocyte differentiation 581
                    lymphocyte differentiation 400
                      B cell differentiation 147
                        B cell lineage commitment + 6
                        B cell selection + 4
                        immature B cell differentiation + 17
                        mature B cell differentiation + 32
                        negative regulation of B cell differentiation + 5
                        positive regulation of B cell differentiation + 17
                        regulation of B cell differentiation + 35
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.