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ONTOLOGY REPORT - ANNOTATIONS


Term:B cell differentiation
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Accession:GO:0030183 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: B lymphocyte differentiation
 related_synonym: B cell development
 alt_id: GO:0042115


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B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO (MGI:MGI:3828349|PMID:17371977) BHF-UCL PMID:17371977 MGI:MGI:3828349 NCBI chrNW_004936532:5,864,851...5,904,005 JBrowse link
G Adgrg3 adhesion G protein-coupled receptor G3 ISO (MGI:MGI:5645196|PMID:24113187) UniProtKB PMID:24113187 MGI:MGI:5645196 NCBI chrNW_004936475:9,699,703...9,707,251 JBrowse link
G Bcl11a BAF chromatin remodeling complex subunit BCL11A ISO (MGI:MGI:2662805|PMID:12717432) MGI PMID:12717432 MGI:MGI:2662805 NCBI chrNW_004936491:6,021,340...6,118,103 JBrowse link
G Bcl2 BCL2 apoptosis regulator ISO (MGI:MGI:2156164|PMID:8170972), (MGI:MGI:85476|PMID:9028316) MGI PMID:8170972, PMID:9028316 MGI:MGI:2156164, MGI:MGI:85476 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Bcl6 BCL6 transcription repressor ISO (MGI:MGI:3028360|PMID:14647274) MGI PMID:14647274 MGI:MGI:3028360 NCBI chrNW_004936578:2,371,976...2,395,034 JBrowse link
G Card11 caspase recruitment domain family member 11 ISO (MGI:MGI:2664641|PMID:12818158) MGI PMID:12818158 MGI:MGI:2664641 NCBI chrNW_004936823:580,438...621,298 JBrowse link
G Cd40lg CD40 ligand ISO (MGI:MGI:3028360|PMID:14647274) MGI PMID:14647274 MGI:MGI:3028360 NCBI chrNW_004936513:10,607,617...10,620,403 JBrowse link
G Cd79a CD79a molecule ISO (MGI:MGI:2149180|PMID:11514602), (MGI:MGI:2687348|PMID:12097390) UniProtKB PMID:11514602, PMID:12097390 MGI:MGI:2149180, MGI:MGI:2687348 NCBI chrNW_004936706:561,195...564,577 JBrowse link
G Cdh17 cadherin 17 ISO (MGI:MGI:3531365|PMID:15688343) UniProtKB PMID:15688343 MGI:MGI:3531365 NCBI chrNW_004936544:7,156,213...7,208,392 JBrowse link
G Cebpg CCAAT enhancer binding protein gamma ISO (PMID:1431100) UniProtKB PMID:1431100 NCBI chrNW_004936570:2,435,672...2,439,056 JBrowse link
G Clcf1 cardiotrophin like cytokine factor 1 ISO (MGI:MGI:1346205|PMID:10500198) MGI PMID:10500198 MGI:MGI:1346205 NCBI chrNW_004936599:2,372,889...2,376,316 JBrowse link
G Dcaf1 DDB1 and CUL4 associated factor 1 ISO (MGI:MGI:5314150|PMID:22157821) UniProtKB PMID:22157821 MGI:MGI:5314150 NCBI chrNW_004936529:2,786,252...2,856,516 JBrowse link
G Dclre1c DNA cross-link repair 1C ISO (MGI:MGI:2447929|PMID:12504013) MGI PMID:12504013 MGI:MGI:2447929 NCBI chrNW_004936613:1,467,797...1,501,107 JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 ISO (MGI:MGI:5644772|PMID:25222125) UniProtKB PMID:25222125 MGI:MGI:5644772 NCBI chrNW_004936653:1,554,534...1,558,832 JBrowse link
G Ep300 E1A binding protein p300 ISO (MGI:MGI:3812266|PMID:18684867) MGI PMID:18684867 MGI:MGI:3812266 NCBI chrNW_004936492:696,982...778,132 JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO (MGI:MGI:5484711|PMID:23531880) MGI PMID:23531880 MGI:MGI:5484711 NCBI chrNW_004936527:5,024,077...5,069,152 JBrowse link
G Flt3 fms related receptor tyrosine kinase 3 ISO (MGI:MGI:4946600|PMID:21228325) UniProtKB PMID:21228325 MGI:MGI:4946600 NCBI chrNW_004936472:23,169,967...23,239,178 JBrowse link
G Fzd9 frizzled class receptor 9 ISO (MGI:MGI:3577530|PMID:15572594) MGI PMID:15572594 MGI:MGI:3577530 NCBI chrNW_004936543:2,707,846...2,709,819 JBrowse link
G Gon4l gon-4 like ISO (MGI:MGI:4821908|PMID:20530203) MGI PMID:20530203 MGI:MGI:4821908 NCBI chrNW_004936580:5,044,536...5,124,575 JBrowse link
G Gps2 G protein pathway suppressor 2 ISO (MGI:MGI:5896692|PMID:28039360) UniProtKB PMID:28039360 MGI:MGI:5896692 NCBI chrNW_004936595:608,730...611,871 JBrowse link
G Hhex hematopoietically expressed homeobox ISO (MGI:MGI:2449266|PMID:12522149) MGI PMID:12522149 MGI:MGI:2449266 NCBI chrNW_004936601:2,137,490...2,143,797 JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO (MGI:MGI:5449477|PMID:23071339)
(MGI:MGI:68746|PMID:7923373)
MGI PMID:7923373, PMID:23071339 MGI:MGI:5449477, MGI:MGI:68746 NCBI chrNW_004936686:1,459,582...1,556,478 JBrowse link
G Jak3 Janus kinase 3 ISO (MGI:MGI:3655405|PMID:9498750) BHF-UCL PMID:9498750 MGI:MGI:3655405 NCBI chrNW_004936596:3,212,593...3,224,426 JBrowse link
G Lyl1 LYL1 basic helix-loop-helix family member ISO (MGI:MGI:3693935|PMID:16514064) UniProtKB PMID:16514064 MGI:MGI:3693935 NCBI chrNW_004936659:2,135,253...2,140,849 JBrowse link
G Ms4a1 membrane spanning 4-domains A1 ISO (PMID:3925015) UniProt PMID:3925015 NCBI chrNW_004936581:2,466,294...2,477,530 JBrowse link
G Msh2 mutS homolog 2 ISO (MGI:MGI:1275867|PMID:9697843) MGI PMID:9697843 MGI:MGI:1275867 NCBI chrNW_004936508:4,943,987...5,013,356 JBrowse link
G Myb MYB proto-oncogene, transcription factor ISO (MGI:MGI:3763573|PMID:17927961) MGI PMID:17927961 MGI:MGI:3763573 NCBI chrNW_004936560:2,797,943...2,828,813 JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 ISO (MGI:MGI:3044463|PMID:15143214) HGNC PMID:15143214 MGI:MGI:3044463 NCBI chrNW_004936718:367,996...399,030 JBrowse link
G Nhej1 non-homologous end joining factor 1 ISO (PMID:16439204) UniProtKB PMID:16439204 NCBI chrNW_004936569:1,494,783...1,578,587 JBrowse link
G Nkx2-3 NK2 homeobox 3 ISO (MGI:MGI:2654966|PMID:12682228) MGI PMID:12682228 MGI:MGI:2654966 NCBI chrNW_004936636:529,669...532,237 JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO (MGI:MGI:3487180|PMID:15459109) MGI PMID:15459109 MGI:MGI:3487180 NCBI chrNW_004936580:6,002,168...6,021,690 JBrowse link
G Onecut1 one cut homeobox 1 ISO (MGI:MGI:3707632|PMID:12874218) MGI PMID:12874218 MGI:MGI:3707632 NCBI chrNW_004936471:14,532,888...14,581,258 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO (MGI:MGI:1329776|PMID:9988280) MGI PMID:9988280 MGI:MGI:1329776 NCBI chrNW_004936480:1,188,408...1,273,210 JBrowse link
G Plcg2 phospholipase C gamma 2 ISO (MGI:MGI:1861532|PMID:10925250) UniProtKB PMID:10925250 MGI:MGI:1861532 NCBI chrNW_004936475:29,248,533...29,377,335 JBrowse link
G Polm DNA polymerase mu ISO (MGI:MGI:3576407|PMID:15789338) MGI PMID:15789338 MGI:MGI:3576407 NCBI chrNW_004936478:19,032,995...19,042,400 JBrowse link
G Pou1f1 POU class 1 homeobox 1 ISO (MGI:MGI:3640879|PMID:9300691) MGI PMID:9300691 MGI:MGI:3640879 NCBI chrNW_004936610:2,262,715...2,279,098 JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 ISO (MGI:MGI:1096020|PMID:9271584) UniProtKB PMID:9271584 MGI:MGI:1096020 NCBI chrNW_004936626:2,390,004...2,472,039 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C ISO (MGI:MGI:3521537|PMID:15557316), (MGI:MGI:3774343|PMID:18249142)
(MGI:MGI:2670259|PMID:12902479), (MGI:MGI:80946|PMID:8666928)
(MGI:MGI:1095647|PMID:9254656)
ARUK-UCL
MGI
PMID:8666928, PMID:9254656, PMID:12902479, PMID:15557316, PMID:18249142 MGI:MGI:1095647, MGI:MGI:2670259, MGI:MGI:3521537, MGI:MGI:3774343, MGI:MGI:80946 NCBI chrNW_004936567:5,266,653...5,378,464 JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J ISO (MGI:MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:MGI:3774343 NCBI chrNW_004936562:1,161,764...1,234,800 JBrowse link
G Rabl3 RAB, member of RAS oncogene family like 3 ISO (MGI:MGI:6405642|PMID:32220963) UniProt PMID:32220963 MGI:MGI:6405642 NCBI chrNW_004936536:7,366,669...7,417,951 JBrowse link
G Rag1 recombination activating 1 ISO (MGI:MGI:2178701|PMID:11976687)
(MGI:MGI:50458|PMID:1547488)
MGI
UniProtKB
PMID:1547488, PMID:11976687 MGI:MGI:2178701, MGI:MGI:50458 NCBI chrNW_004936533:1,817,135...1,827,393 JBrowse link
G Rag2 recombination activating 2 ISO (MGI:MGI:50458|PMID:1547488), (MGI:MGI:50459|PMID:1547487)
(MGI:MGI:2179579|PMID:11980719), (MGI:MGI:3709144|PMID:14595002)
UniProtKB
MGI
PMID:1547487, PMID:1547488, PMID:11980719, PMID:14595002 MGI:MGI:2179579, MGI:MGI:3709144, MGI:MGI:50458, MGI:MGI:50459 NCBI chrNW_004936533:1,801,207...1,807,431 JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:MGI:2178898|PMID:11967543) MGI PMID:11967543 MGI:MGI:2178898 NCBI chrNW_004936477:3,354,336...3,445,248 JBrowse link
G Sp3 Sp3 transcription factor ISO (MGI:MGI:2670314|PMID:12676787) MGI PMID:12676787 MGI:MGI:2670314 NCBI chrNW_004936509:3,740,393...3,782,873 JBrowse link
G Tcirg1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 ISO (MGI:MGI:3054344|PMID:15294947)
(MGI:MGI:3055645|PMID:15284856), (MGI:MGI:3655025|PMID:16797412)
MGI PMID:15284856, PMID:15294947, PMID:16797412 MGI:MGI:3054344, MGI:MGI:3055645, MGI:MGI:3655025 NCBI chrNW_004936599:2,070,211...2,079,169 JBrowse link
G Tpd52 tumor protein D52 ISO (PMID:15576473) UniProtKB PMID:15576473 NCBI chrNW_004936656:3,827,764...3,868,828 JBrowse link
G Tshr thyroid stimulating hormone receptor ISO (MGI:MGI:3640879|PMID:9300691) MGI PMID:9300691 MGI:MGI:3640879 NCBI chrNW_004936488:9,428,053...9,560,856 JBrowse link
G Yy1 YY1 transcription factor ISO (MGI:MGI:5484711|PMID:23531880) MGI PMID:23531880 MGI:MGI:5484711 NCBI chrNW_004936604:3,911,407...3,945,405 JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 ISO (MGI:MGI:5300225|PMID:22201126) MGI PMID:22201126 MGI:MGI:5300225 NCBI chrNW_004936495:8,212,136...8,238,876 JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7A ISO (MGI:MGI:3710692|PMID:17495164) UniProt PMID:17495164 MGI:MGI:3710692 NCBI chrNW_004936588:2,310,975...2,321,790 JBrowse link
B cell affinity maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO (MGI:MGI:65977|PMID:7680896) MGI PMID:7680896 MGI:MGI:65977 NCBI chrNW_004936813:429,400...467,481 JBrowse link
B cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2 apoptosis regulator ISO (MGI:MGI:78866|PMID:8788039) MGI PMID:8788039 MGI:MGI:78866 NCBI chrNW_004936497:2,209,136...2,373,580 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO (MGI:MGI:78866|PMID:8788039) MGI PMID:8788039 MGI:MGI:78866 NCBI chrNW_004936590:4,722,914...4,887,615 JBrowse link
G Rag2 recombination activating 2 ISO (MGI:MGI:78866|PMID:8788039) MGI PMID:8788039 MGI:MGI:78866 NCBI chrNW_004936533:1,801,207...1,807,431 JBrowse link
G Tcf3 transcription factor 3 ISO (PMID:15030778) UniProtKB PMID:15030778 NCBI chrNW_004936588:884,817...913,052 JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:78866|PMID:8788039) MGI PMID:8788039 MGI:MGI:78866 NCBI chrNW_004936595:919,807...935,367 JBrowse link
B cell negative selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2 antagonist/killer 1 ISO (MGI:MGI:3588597|PMID:16055554) MGI PMID:16055554 MGI:MGI:3588597 NCBI chrNW_004936476:25,347,608...25,354,772 JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO (MGI:MGI:3588597|PMID:16055554) MGI PMID:16055554 MGI:MGI:3588597 NCBI chrNW_004936664:2,968,103...2,973,652 JBrowse link
B-1 B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd19 CD19 molecule ISO (MGI:MGI:74944|PMID:7543183) UniProt PMID:7543183 MGI:MGI:74944 NCBI chrNW_004936501:11,793,903...11,807,410 JBrowse link
G Malt1 MALT1 paracaspase ISO (MGI:MGI:3629264|PMID:14614861) MGI PMID:14614861 MGI:MGI:3629264 NCBI chrNW_004936497:5,854,361...5,910,719 JBrowse link
B-1 B cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slamf8 SLAM family member 8 ISO (MGI:MGI:6215454|PMID:11313408) UniProt PMID:11313408 MGI:MGI:6215454 NCBI chrNW_004936740:776,557...786,182 JBrowse link
B-1a B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmtm7 CKLF like MARVEL transmembrane domain containing 7 ISO (MGI:MGI:5554324|PMID:24080084) MGI PMID:24080084 MGI:MGI:5554324 NCBI chrNW_004936473:22,932,965...22,947,309 JBrowse link
G Nfatc1 nuclear factor of activated T cells 1 ISO (MGI:MGI:2680742|PMID:14595020) MGI PMID:14595020 MGI:MGI:2680742 NCBI chrNW_004936616:484,062...584,950 JBrowse link
G Plcl2 phospholipase C like 2 ISO (MGI:MGI:2677607|PMID:14517301) MGI PMID:14517301 MGI:MGI:2677607 NCBI chrNW_004936473:9,628,612...9,801,713 JBrowse link
follicular B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcg2 phospholipase C gamma 2 ISO (MGI:MGI:2679743|PMID:12928432) MGI PMID:12928432 MGI:MGI:2679743 NCBI chrNW_004936475:29,248,533...29,377,335 JBrowse link
germinal center B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh17 cadherin 17 ISO (MGI:MGI:3531365|PMID:15688343) UniProtKB PMID:15688343 MGI:MGI:3531365 NCBI chrNW_004936544:7,156,213...7,208,392 JBrowse link
G Il21 interleukin 21 ISO (MGI:MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:MGI:5450752 NCBI chrNW_004936662:1,689,879...1,696,883 JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 ISO (MGI:MGI:5547463|PMID:23997217) MGI PMID:23997217 MGI:MGI:5547463 NCBI chrNW_004936606:3,144,616...3,158,825 JBrowse link
G Pou2af1 POU class 2 homeobox associating factor 1 ISO (MGI:MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:MGI:5450752 NCBI chrNW_004936612:3,032,015...3,055,015 JBrowse link
immature B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fnip1 folliculin interacting protein 1 ISO (MGI:MGI:5436190|PMID:22608497) MGI PMID:22608497 MGI:MGI:5436190 NCBI chrNW_004936647:3,329,097...3,428,170 JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 ISO (PMID:27016798) UniProtKB PMID:27016798 NCBI chrNW_004936484:17,653,519...17,661,811 JBrowse link
G Kit KIT proto-oncogene, receptor tyrosine kinase ISO (MGI:MGI:3040777|PMID:15067126) UniProtKB PMID:15067126 MGI:MGI:3040777 NCBI chrNW_004936482:17,162,854...17,238,319 JBrowse link
G Syvn1 synoviolin 1 ISO (MGI:MGI:6220623|PMID:29907570) UniProt PMID:29907570 MGI:MGI:6220623 NCBI chrNW_004936599:4,235,779...4,243,395 JBrowse link
marginal zone B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl3 BCL3 transcription coactivator ISO (MGI:MGI:85481|PMID:9009202) MGI PMID:9009202 MGI:MGI:85481 NCBI chrNW_004936706:1,410,848...1,427,822 JBrowse link
G Cdh17 cadherin 17 ISO (MGI:MGI:3531365|PMID:15688343) UniProtKB PMID:15688343 MGI:MGI:3531365 NCBI chrNW_004936544:7,156,213...7,208,392 JBrowse link
G Dll1 delta like canonical Notch ligand 1 ISO (MGI:MGI:3044313|PMID:15146182), (MGI:MGI:3838059|PMID:19217325) UniProtKB PMID:15146182, PMID:19217325 MGI:MGI:3044313, MGI:MGI:3838059 NCBI chrNW_004937098:212,704...220,589 JBrowse link
G Dock10 dedicator of cytokinesis 10 ISO (MGI:MGI:5818419|PMID:25729399) UniProtKB PMID:25729399 MGI:MGI:5818419 NCBI chrNW_004936569:6,274,747...6,462,265 JBrowse link
G Dock11 dedicator of cytokinesis 11 ISO (MGI:MGI:5818419|PMID:25729399) UniProtKB PMID:25729399 MGI:MGI:5818419 NCBI chrNW_004936479:11,148,877...11,334,381 JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase ISO (MGI:MGI:3838059|PMID:19217325) UniProtKB PMID:19217325 MGI:MGI:3838059 NCBI chrNW_004936823:283,207...290,970 JBrowse link
G Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase ISO (MGI:MGI:3838059|PMID:19217325) UniProtKB PMID:19217325 MGI:MGI:3838059 NCBI chrNW_004936492:3,547,345...3,561,940 JBrowse link
G Notch2 notch receptor 2 ISO (MGI:MGI:3838059|PMID:19217325) UniProtKB PMID:19217325 MGI:MGI:3838059 NCBI chrNW_004936872:454,273...539,544 JBrowse link
G Ptk2b protein tyrosine kinase 2 beta ISO (MGI:MGI:1860716|PMID:10881171) UniProtKB PMID:10881171 MGI:MGI:1860716 NCBI chrNW_004936675:216,970...325,670 JBrowse link
mature B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou2f2 POU class 2 homeobox 2 ISO (MGI:MGI:53043|PMID:8096198) MGI PMID:8096198 MGI:MGI:53043 NCBI chrNW_004936706:335,613...393,854 JBrowse link
memory B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 ISO (MGI:MGI:2387354|PMID:10755614) UniProt PMID:10755614 MGI:MGI:2387354 NCBI chrNW_004936470:15,860,669...15,934,500 JBrowse link
negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt3 fms related receptor tyrosine kinase 3 ISO (MGI:MGI:3623701|PMID:16618805) MGI PMID:16618805 MGI:MGI:3623701 NCBI chrNW_004936472:23,169,967...23,239,178 JBrowse link
G Hmgb3 high mobility group box 3 ISO (MGI:MGI:2670545|PMID:12714519) MGI PMID:12714519 MGI:MGI:2670545 NCBI chrNW_004936714:1,523,016...1,527,301 JBrowse link
G Id2 inhibitor of DNA binding 2 ISO (MGI:MGI:3805135|PMID:18523151) MGI PMID:18523151 MGI:MGI:3805135 NCBI chrNW_004936532:5,236,175...5,238,689 JBrowse link
G Sfrp1 secreted frizzled related protein 1 ISO (PMID:18941195)
(MGI:MGI:3814493|PMID:18941195)
UniProtKB PMID:18941195 MGI:MGI:3814493 NCBI chrNW_004936785:1,276,478...1,320,397 JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cr1 complement C3b/C4b receptor 1 (Knops blood group) ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itm2a integral membrane protein 2A ISO (MGI:MGI:5613782|PMID:24831988) MGI PMID:24831988 MGI:MGI:5613782 NCBI chrNW_004936547:1,260,705...1,267,443 JBrowse link
G Lgals1 galectin 1 ISO (MGI:MGI:5301217|PMID:21753146) MGI PMID:21753146 MGI:MGI:5301217 NCBI chrNW_004936492:3,407,704...3,411,197 JBrowse link
G Lgals8 galectin 8 ISO (MGI:MGI:5301217|PMID:21753146) MGI PMID:21753146 MGI:MGI:5301217 NCBI chrNW_004936484:16,357,433...16,374,675 JBrowse link
G Nkx2-3 NK2 homeobox 3 ISO (MGI:MGI:1888604|PMID:10926756) MGI PMID:10926756 MGI:MGI:1888604 NCBI chrNW_004936636:529,669...532,237 JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp11c ATPase phospholipid transporting 11C ISO (MGI:MGI:5002406|PMID:21423173) UniProtKB PMID:21423173 MGI:MGI:5002406 NCBI chrNW_004936513:7,701,733...7,889,753 JBrowse link
G Bad BCL2 associated agonist of cell death ISO (MGI:MGI:3029504|PMID:12431371) MGI PMID:12431371 MGI:MGI:3029504 NCBI chrNW_004936599:4,924,349...4,933,683 JBrowse link
G Il2rg interleukin 2 receptor subunit gamma ISO (MGI:MGI:1095961|PMID:9252128) MGI PMID:9252128 MGI:MGI:1095961 NCBI chrNW_004936762:487,414...491,028 JBrowse link
G Il7 interleukin 7 ISO (MGI:MGI:3655025|PMID:16797412) MGI PMID:16797412 MGI:MGI:3655025 NCBI chrNW_004936702:110,625...162,957 JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D ISO (MGI:MGI:1266928|PMID:9620849), (MGI:MGI:1354084|PMID:10704460) MGI PMID:9620849, PMID:10704460 MGI:MGI:1266928, MGI:MGI:1354084 NCBI chrNW_004936525:4,046,609...4,154,715 JBrowse link
G Mmp14 matrix metallopeptidase 14 ISO (MGI:MGI:5013661|PMID:21572390) UniProtKB PMID:21572390 MGI:MGI:5013661 NCBI chrNW_004936722:1,447,189...1,457,632 JBrowse link
G Nckap1l NCK associated protein 1 like ISO (MGI:MGI:3818191|PMID:19015308) UniProtKB PMID:19015308 MGI:MGI:3818191 NCBI chrNW_004936512:11,683,330...11,734,423 JBrowse link
G Pcid2 PCI domain containing 2 ISO (MGI:MGI:4839685|PMID:20870947) UniProtKB PMID:20870947 MGI:MGI:4839685 NCBI chrNW_004936472:440,440...464,116 JBrowse link
G Ppp2r3c protein phosphatase 2 regulatory subunit B''gamma ISO (MGI:MGI:3589325|PMID:16129705) MGI PMID:16129705 MGI:MGI:3589325 NCBI chrNW_004936494:9,247,600...9,283,019 JBrowse link
G Prdm1 PR/SET domain 1 NOT ISO (MGI:MGI:3826899|PMID:18845144) MGI PMID:18845144 MGI:MGI:3826899 NCBI chrNW_004936564:2,594,362...2,690,680 JBrowse link
G Stat5b signal transducer and activator of transcription 5B ISO (MGI:MGI:1889695|PMID:10979977) MGI PMID:10979977 MGI:MGI:1889695 NCBI chrNW_004936490:17,022,268...17,043,751 JBrowse link
G Syk spleen associated tyrosine kinase ISO (PMID:18369315)
(MGI:MGI:77315|PMID:7477353)
(MGI:MGI:77314|PMID:7477352)
CACAO
MGI
PMID:7477352, PMID:7477353, PMID:18369315 MGI:MGI:77314, MGI:MGI:77315 NCBI chrNW_004936780:1,553,605...1,601,036 JBrowse link
G Xbp1 X-box binding protein 1 ISO (PMID:11460154) UniProtKB PMID:11460154 NCBI chrNW_004936657:2,891,171...2,895,409 JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chrNW_004936557:5,834,874...5,838,502 JBrowse link
G Il2 interleukin 2 ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chrNW_004936662:1,594,953...1,599,625 JBrowse link
G Xbp1 X-box binding protein 1 ISO (PMID:11460154) UniProtKB PMID:11460154 NCBI chrNW_004936657:2,891,171...2,895,409 JBrowse link
pre-B cell allelic exclusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase ISO (MGI:MGI:3848557|PMID:19448632) UniProtKB PMID:19448632 MGI:MGI:3848557 NCBI chrNW_004936551:359,134...534,672 JBrowse link
G Rag1 recombination activating 1 ISO (MGI:MGI:3848557|PMID:19448632) UniProtKB PMID:19448632 MGI:MGI:3848557 NCBI chrNW_004936533:1,817,135...1,827,393 JBrowse link
G Rag2 recombination activating 2 ISO (MGI:MGI:3848557|PMID:19448632) UniProtKB PMID:19448632 MGI:MGI:3848557 NCBI chrNW_004936533:1,801,207...1,807,431 JBrowse link
pre-B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp11c ATPase phospholipid transporting 11C ISO (MGI:MGI:5002406|PMID:21423173) UniProtKB PMID:21423173 MGI:MGI:5002406 NCBI chrNW_004936513:7,701,733...7,889,753 JBrowse link
G Foxp1 forkhead box P1 ISO (MGI:MGI:3662963|PMID:16819554) MGI PMID:16819554 MGI:MGI:3662963 NCBI chrNW_004936603:2,631,781...3,146,104 JBrowse link
G LOC101968601 signal transducer CD24 ISO (MGI:MGI:2179980|PMID:9028339), (MGI:MGI:74794|PMID:7795661) MGI PMID:7795661, PMID:9028339 MGI:MGI:2179980, MGI:MGI:74794 NCBI chrNW_004936491:16,706,745...16,707,010 JBrowse link
regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankle1 ankyrin repeat and LEM domain containing 1 NOT ISO (MGI:MGI:5800654|PMID:27010503) UniProtKB PMID:27010503 MGI:MGI:5800654 NCBI chrNW_004936596:3,568,810...3,573,506 JBrowse link
G Card11 caspase recruitment domain family member 11 ISO (MGI:MGI:3039643|PMID:12867038) MGI PMID:12867038 MGI:MGI:3039643 NCBI chrNW_004936823:580,438...621,298 JBrowse link
G Cyld CYLD lysine 63 deubiquitinase ISO (MGI:MGI:3656194|PMID:16501569) MGI PMID:16501569 MGI:MGI:3656194 NCBI chrNW_004936475:3,750,917...3,812,118 JBrowse link
G Ikzf3 IKAROS family zinc finger 3 ISO (MGI:MGI:1307021|PMID:9806640) UniProtKB PMID:9806640 MGI:MGI:1307021 NCBI chrNW_004936490:14,939,693...15,025,728 JBrowse link
G LOC101968601 signal transducer CD24 ISO (MGI:MGI:2179980|PMID:9028339), (MGI:MGI:74794|PMID:7795661) MGI PMID:7795661, PMID:9028339 MGI:MGI:2179980, MGI:MGI:74794 NCBI chrNW_004936491:16,706,745...16,707,010 JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 ISO (MGI:MGI:3044463|PMID:15143214) MGI PMID:15143214 MGI:MGI:3044463 NCBI chrNW_004936718:367,996...399,030 JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 ISO (MGI:MGI:1095647|PMID:9254656) MGI PMID:9254656 MGI:MGI:1095647 NCBI chrNW_004936709:864,206...884,630 JBrowse link
G Slamf8 SLAM family member 8 ISO (MGI:MGI:6215454|PMID:11313408) UniProt PMID:11313408 MGI:MGI:6215454 NCBI chrNW_004936740:776,557...786,182 JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 ISO (MGI:MGI:5779430|PMID:27102483) UniProtKB PMID:27102483 MGI:MGI:5779430 NCBI chrNW_004936495:12,045,679...12,050,737 JBrowse link
G Zfp36l2 ZFP36 ring finger protein like 2 ISO (MGI:MGI:5779430|PMID:27102483) UniProtKB PMID:27102483 MGI:MGI:5779430 NCBI chrNW_004936508:8,617,185...8,620,823 JBrowse link
transitional one stage B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO (MGI:MGI:3839222|PMID:19228876) MGI PMID:19228876 MGI:MGI:3839222 NCBI chrNW_004936487:17,690,206...17,819,619 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11998
    immune system process 1918
      leukocyte activation 789
        lymphocyte activation 639
          lymphocyte differentiation 343
            B cell differentiation 111
              B cell lineage commitment + 6
              B cell selection + 3
              immature B cell differentiation + 11
              mature B cell differentiation + 29
              negative regulation of B cell differentiation + 5
              positive regulation of B cell differentiation + 15
              regulation of B cell differentiation + 30
Path 2
Term Annotations click to browse term
  biological_process 11998
    developmental process 5648
      anatomical structure development 5286
        multicellular organism development 4845
          system development 4567
            immune system development 933
              hematopoietic or lymphoid organ development 873
                hemopoiesis 826
                  leukocyte differentiation 513
                    lymphocyte differentiation 343
                      B cell differentiation 111
                        B cell lineage commitment + 6
                        B cell selection + 3
                        immature B cell differentiation + 11
                        mature B cell differentiation + 29
                        negative regulation of B cell differentiation + 5
                        positive regulation of B cell differentiation + 15
                        regulation of B cell differentiation + 30
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.