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ONTOLOGY REPORT - ANNOTATIONS


Term:heparan sulfate proteoglycan catabolic process
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Accession:GO:0030200 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.
Synonyms:exact_synonym: heparan sulfate proteoglycan breakdown;   heparan sulfate proteoglycan catabolism;   heparan sulfate proteoglycan degradation;   heparan sulphate proteoglycan catabolic process;   heparan sulphate proteoglycan catabolism
 related_synonym: heparin proteoglycan catabolic process


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heparan sulfate proteoglycan catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07030903.1 RGD:1600115
G Gpc1 glypican 1 JBrowse link 9 99,998,275 100,026,818 RGD:1600115
RGD:1624291
G Hpse heparanase JBrowse link 14 10,534,358 10,576,686 RGD:1600115
RGD:1624291
G Sgsh N-sulfoglucosamine sulfohydrolase JBrowse link 10 108,469,312 108,479,094 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      primary metabolic process 10563
        protein metabolic process 6070
          glycoprotein metabolic process 357
            proteoglycan metabolic process 74
              proteoglycan catabolic process 5
                heparan sulfate proteoglycan catabolic process 4
Path 2
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      organic substance metabolic process 11297
        macromolecule metabolic process 9765
          protein metabolic process 6070
            protein catabolic process 970
              glycoprotein catabolic process 22
                proteoglycan catabolic process 5
                  heparan sulfate proteoglycan catabolic process 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.