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ONTOLOGY REPORT - ANNOTATIONS


Term:keratinocyte differentiation
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Accession:GO:0030216 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.
Synonyms:exact_synonym: keratinocyte cell differentiation


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keratinocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca12 ATP binding cassette subfamily A member 12 JBrowse link 9 78,521,477 78,693,421 RGD:1624291
G Acer1 alkaline ceramidase 1 JBrowse link 9 10,061,978 10,093,588 RGD:1624291
G Adam9 ADAM metallopeptidase domain 9 JBrowse link 16 71,810,377 71,887,926 RGD:1624291
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:1624291
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:1624291
RGD:13792537
G Asah1 N-acylsphingosine amidohydrolase 1 JBrowse link 16 53,998,604 54,030,006 RGD:1600115
RGD:1624291
G Bcr BCR activator of RhoGEF and GTPase JBrowse link 20 14,421,250 14,546,406 RGD:1624291
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
RGD:13792537
G Cers3 ceramide synthase 3 JBrowse link 1 127,706,618 127,781,041 RGD:1624291
G Clic4 chloride intracellular channel 4 JBrowse link 5 153,568,937 153,625,669 RGD:1600115
RGD:1624291
G Csta cystatin A JBrowse link 11 67,555,792 67,566,980 RGD:1624291
G Dsg4 desmoglein 4 JBrowse link 18 12,056,113 12,092,858 RGD:1624291
G Dsp desmoplakin JBrowse link 17 27,286,811 27,334,453 RGD:1624291
G Epha2 Eph receptor A2 JBrowse link 5 159,845,773 159,874,203 RGD:1624291
G Evpl envoplakin JBrowse link 10 105,100,538 105,116,802 RGD:1624291
G Foxn1 forkhead box N1 JBrowse link 10 65,621,142 65,634,666 RGD:1300512
RGD:1624291
G Intu inturned planar cell polarity protein JBrowse link 2 127,589,325 127,611,705 RGD:1624291
RGD:1600115
G Irf6 interferon regulatory factor 6 JBrowse link 13 111,870,121 111,889,328 RGD:1624291
G Ivl involucrin JBrowse link 2 192,761,171 192,773,346 RGD:1624291
G Krt10 keratin 10 JBrowse link 10 87,296,445 87,301,307 RGD:1624291
G Krt16 keratin 16 JBrowse link 10 88,149,210 88,152,167 RGD:1624291
G Lats1 large tumor suppressor kinase 1 JBrowse link 1 1,784,078 1,817,310 RGD:1624291
G Lats2 large tumor suppressor kinase 2 JBrowse link 15 37,943,609 37,995,175 RGD:1624291
G Loricrin loricrin cornified envelope precursor protein JBrowse link 2 191,984,455 191,990,713 RGD:1624291
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 JBrowse link 7 12,918,352 12,922,509 RGD:1624291
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:1624291
RGD:1600115
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:1624291
RGD:1600115
G Pou2f3 POU class 2 homeobox 3 JBrowse link 8 47,412,063 47,495,042 RGD:1624291
G Pou3f1 POU class 3 homeobox 1 JBrowse link 5 142,643,599 142,646,580 RGD:1624291
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
G Sav1 salvador family WW domain containing protein 1 JBrowse link 6 92,376,470 92,398,678 RGD:1624291
G Scel sciellin JBrowse link 15 87,689,190 87,820,731 RGD:1624291
G Sfn stratifin JBrowse link 5 151,823,422 151,824,937 RGD:1624291
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 JBrowse link 8 22,648,323 22,739,468 RGD:1624291
G Sprr1a small proline-rich protein 1A JBrowse link 2 192,669,143 192,671,059 RGD:1624291
G Sprr1b small proline-rich protein 1B JBrowse link 2 192,622,972 192,624,848 RGD:1624291
G St14 ST14 transmembrane serine protease matriptase JBrowse link 8 32,240,113 32,280,813 RGD:1624291
RGD:13792537
G Stk4 serine/threonine kinase 4 JBrowse link 3 160,467,552 160,546,540 RGD:1624291
G Tgm1 transglutaminase 1 JBrowse link 15 34,378,136 34,393,150 RGD:1624291
G Tgm3 transglutaminase 3 JBrowse link 3 122,544,783 122,580,836 RGD:1624291
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:1624291
G Tsg101 tumor susceptibility 101 JBrowse link 1 102,941,151 102,971,017 RGD:1624291
G Txnip thioredoxin interacting protein JBrowse link 2 198,683,168 198,686,971 RGD:1624291
G Ugcg UDP-glucose ceramide glucosyltransferase JBrowse link 5 76,376,722 76,419,564 RGD:1600115
RGD:1624291
G Wnt16 Wnt family member 16 JBrowse link 4 49,369,246 49,388,156 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
G Yap1 Yes1 associated transcriptional regulator JBrowse link 8 6,133,014 6,204,240 RGD:1624291
corneocyte desquamation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdsn corneodesmosin JBrowse link 20 3,704,626 3,707,266 RGD:1624291
corneocyte development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnase1l2 deoxyribonuclease 1 like 2 JBrowse link 10 13,812,335 13,814,514 RGD:1624291
G Psap prosaposin JBrowse link 20 29,831,302 29,856,876 RGD:1600115
RGD:1624291
cornification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp14 caspase 14 JBrowse link 7 13,938,376 13,944,286 RGD:1600115
G Cers3 ceramide synthase 3 JBrowse link 1 127,706,618 127,781,041 RGD:1624291
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 JBrowse link 4 116,261,796 116,278,615 RGD:1624291
G Tmem79 transmembrane protein 79 JBrowse link 2 187,701,522 187,706,452 RGD:1624291
keratinization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07033579.3 RGD:1600115
G AABR07033580.1 RGD:1600115
G Abca12 ATP binding cassette subfamily A member 12 JBrowse link 9 78,521,477 78,693,421 RGD:1624291
G Cdh3 cadherin 3 JBrowse link 19 38,668,957 38,719,801 RGD:1624291
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:4142790
G Ivl involucrin JBrowse link 2 192,761,171 192,773,346 RGD:1600115
G Kazn kazrin, periplakin interacting protein JBrowse link 5 160,637,235 161,730,513 RGD:1600115
G Kb15 type II keratin Kb15 JBrowse link 7 143,208,034 143,217,771 RGD:1624291
G Krt16 keratin 16 JBrowse link 10 88,149,210 88,152,167 RGD:1624291
G Krt17 keratin 17 JBrowse link 10 88,158,993 88,163,712 RGD:1624291
G Krt2 keratin 2 JBrowse link 7 143,412,858 143,420,463 RGD:1600115
RGD:1624291
G Sfn stratifin JBrowse link 5 151,823,422 151,824,937 RGD:1624291
G Sharpin SHANK-associated RH domain interactor JBrowse link 7 117,413,151 117,417,455 RGD:1624291
G Sprr1a small proline-rich protein 1A JBrowse link 2 192,669,143 192,671,059 RGD:1600115
G Tgm1 transglutaminase 1 JBrowse link 15 34,378,136 34,393,150 RGD:1600115
G Tgm3 transglutaminase 3 JBrowse link 3 122,544,783 122,580,836 RGD:1600115
keratinocyte development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl11b BAF chromatin remodeling complex subunit BCL11B JBrowse link 6 131,834,097 131,927,251 RGD:1624291
G Exph5 exophilin 5 JBrowse link 8 57,885,932 57,962,574 RGD:1624291
G Flnb filamin B JBrowse link 15 18,750,152 18,883,019 RGD:1624291
G Fosl2 FOS like 2, AP-1 transcription factor subunit JBrowse link 6 25,598,936 25,616,995 RGD:1624291
G Ift74 intraflagellar transport 74 JBrowse link 5 113,579,065 113,682,485 RGD:1624291
G Kdf1 keratinocyte differentiation factor 1 JBrowse link 5 151,740,902 151,752,863 RGD:1624291
G Krt10 keratin 10 JBrowse link 10 87,296,445 87,301,307 RGD:1624291
G Krt2 keratin 2 JBrowse link 7 143,412,858 143,420,463 RGD:1624291
RGD:1600115
G LOC100911383 uncharacterized LOC100911383 RGD:1600115
G Palld palladin, cytoskeletal associated protein JBrowse link 16 31,865,712 31,948,168 RGD:1624291
G Sfn stratifin JBrowse link 5 151,823,422 151,824,937 RGD:1624291
G Tfap2a transcription factor AP-2 alpha JBrowse link 17 24,653,342 24,670,457 RGD:1624291
G Tfap2c transcription factor AP-2 gamma JBrowse link 3 170,550,314 170,558,197 RGD:1624291
negative regulation of cornification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdsn corneodesmosin JBrowse link 20 3,704,626 3,707,266 RGD:1624291
negative regulation of keratinocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grhl2 grainyhead-like transcription factor 2 JBrowse link 7 76,058,623 76,197,360 RGD:1624291
G Hoxa7 homeobox A7 JBrowse link 4 82,184,299 82,187,890 RGD:1624291
G Msx2 msh homeobox 2 JBrowse link 17 11,683,862 11,689,527 RGD:1624291
RGD:1600115
G Ovol2 ovo-like zinc finger 2 JBrowse link 3 138,433,990 138,464,511 RGD:1624291
G Reg3a regenerating islet-derived 3 alpha JBrowse link 4 109,477,893 109,480,659 RGD:1600115
RGD:1624291
G Reg3g regenerating family member 3 gamma JBrowse link 4 109,529,679 109,532,234 RGD:1624291
RGD:1600115
G Srsf6 serine and arginine rich splicing factor 6 JBrowse link 3 159,305,345 159,310,668 RGD:1624291
RGD:1600115
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:1624291
positive regulation of keratinocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox15b arachidonate 15-lipoxygenase, type B JBrowse link 10 55,773,748 55,783,489 RGD:1600115
RGD:1624291
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Etv4 ETS variant transcription factor 4 JBrowse link 10 89,685,058 89,700,300 RGD:1624291
G Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:1624291
G Macroh2a1 macroH2A.1 histone JBrowse link 17 9,282,109 9,344,698 RGD:1624291
G Macroh2a2 macroH2A.2 histone JBrowse link 20 31,352,924 31,402,483 RGD:1624291
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
RGD:1600115
G Ncoa3 nuclear receptor coactivator 3 JBrowse link 3 162,692,176 162,788,582 RGD:1600115
RGD:1624291
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 JBrowse link 10 81,648,216 81,653,717 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Numa1 nuclear mitotic apparatus protein 1 JBrowse link 1 167,044,544 167,091,453 RGD:1624291
G Ovol2 ovo-like zinc finger 2 JBrowse link 3 138,433,990 138,464,511 RGD:1624291
G Prkch protein kinase C, eta JBrowse link 6 96,479,243 96,677,368 RGD:1624291
RGD:1600115
G Trim16 tripartite motif-containing 16 JBrowse link 10 49,231,660 49,254,653 RGD:1624291
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1600115
RGD:1624291
regulation of keratinocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd109 CD109 molecule JBrowse link 8 85,951,420 86,065,411 RGD:1624291
G Errfi1 ERBB receptor feedback inhibitor 1 JBrowse link 5 167,951,564 167,966,011 RGD:1624291
RGD:13792537
RGD:1600115
G Grhl1 grainyhead-like transcription factor 1 JBrowse link 6 43,734,837 43,795,757 RGD:1624291
G Krt36 keratin 36 JBrowse link 10 88,016,602 88,019,967 RGD:1624291
G Krt84 keratin 84 JBrowse link 7 143,180,212 143,187,684 RGD:1624291
G Rock1 Rho-associated coiled-coil containing protein kinase 1 JBrowse link 18 1,273,490 1,390,790 RGD:1600115
RGD:1624291
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:1600115
RGD:1624291
G Sgpp1 sphingosine-1-phosphate phosphatase 1 JBrowse link 6 98,675,324 98,696,492 RGD:1600115
RGD:1624291
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1624291
RGD:1600115
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 6 103,308,032 103,313,074 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    developmental process 6735
      anatomical structure development 6181
        animal organ development 3973
          skin development 257
            keratinocyte differentiation 103
              keratinization + 21
              keratinocyte development + 16
              limb granular cell differentiation + 0
              limb spinous cell differentiation + 0
              negative regulation of keratinocyte differentiation + 9
              positive regulation of keratinocyte differentiation + 15
              regulation of keratinocyte differentiation + 33
Path 2
Term Annotations click to browse term
  biological_process 19858
    developmental process 6735
      anatomical structure development 6181
        tissue development 2069
          epithelium development 1231
            epithelial cell differentiation 680
              epidermal cell differentiation 183
                keratinocyte differentiation 103
                  keratinization + 21
                  keratinocyte development + 16
                  limb granular cell differentiation + 0
                  limb spinous cell differentiation + 0
                  negative regulation of keratinocyte differentiation + 9
                  positive regulation of keratinocyte differentiation + 15
                  regulation of keratinocyte differentiation + 33
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.