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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet formation
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Accession:GO:0030220 term browser browse the term
Definition:The process in which platelets bud from long processes extended by megakaryocytes.
Synonyms:exact_synonym: platelet extrusion


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platelet formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn1 actinin, alpha 1 IEA
ISO
GO_REF:0000107
(PMID:23434115)
Ensembl
RGD
PMID:23434115 GO_REF:0000107 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Cib1 calcium and integrin binding 1 ISS
ISO
GO_REF:0000024
(MGI:5314162|PMID:22128142)
UniProt
RGD
PMID:22128142 GO_REF:0000024, MGI:5314162 NCBI chr 1:142,014,962...142,020,461
Ensembl chr 1:142,014,958...142,020,525
JBrowse link
G Clec1b C-type lectin domain family 1, member B ISO MGI:1889810 (MGI:5512895|PMID:23112346) RGD PMID:23112346 MGI:5512895 NCBI chr 4:163,161,941...163,170,470
Ensembl chr 4:163,162,211...163,170,466
JBrowse link
G Ep300 E1A binding protein p300 ISO MGI:3813243|MGI:97076 (MGI:3812266|PMID:18684867) RGD PMID:18684867 MGI:3812266 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Gata1 GATA binding protein 1 ISO (PMID:10700180), (PMID:11675338), (PMID:12483298)
MGI:2177587 (MGI:894135|PMID:9233806)
RGD PMID:9233806, PMID:10700180, PMID:11675338, PMID:12483298 MGI:894135 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Mef2c myocyte enhancer factor 2C IEA
ISO
ISS
GO_REF:0000107
(MGI:3844189|PMID:19211936)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19211936 GO_REF:0000024, GO_REF:0000107, MGI:3844189 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Mfap2 microfibril associated protein 2 ISO MGI:3790750 (MGI:3785344|PMID:18281502) RGD PMID:18281502 MGI:3785344 NCBI chr 5:159,534,202...159,539,750
Ensembl chr 5:159,534,202...159,539,750
JBrowse link
G Mpig6b megakaryocyte and platelet inhibitory receptor G6b IEA
ISO
IBA
ISS
GO_REF:0000107
MGI:1913287|MGI:2675830|MGI:96055|MGI:99511 (MGI:5494903|PMID:23509158), (MGI:5512895|PMID:23112346)
PMID:21873635
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23112346, PMID:23509158, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:5494903, MGI:5512895, RGD:13792537 NCBI chr20:5,054,419...5,056,655
Ensembl chr20:5,054,583...5,056,488
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor ISO MGI:1276116 (MGI:3812266|PMID:18684867) RGD PMID:18684867 MGI:3812266 NCBI chr 5:137,268,412...137,282,032
Ensembl chr 5:137,269,480...137,281,298
JBrowse link
G Myh9 myosin, heavy chain 9 ISO (PMID:12237319) RGD PMID:12237319 NCBI chr 7:118,740,005...118,792,507
Ensembl chr 7:118,741,110...118,792,625
JBrowse link
G Myh9l1 myosin heavy chain 9-like 1 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 7:118,991,251...119,071,722
Ensembl chr 7:118,992,356...119,071,712
Ensembl chr 7:118,992,356...119,071,712
JBrowse link
G Nbeal2 neurobeachin-like 2 ISO (PMID:21765411) RGD PMID:21765411 NCBI chr 8:118,893,987...118,924,390
Ensembl chr 8:118,893,995...118,926,613
JBrowse link
G Ppbp pro-platelet basic protein TAS RGD PMID:11785982 RGD:70252 NCBI chr14:18,852,433...18,853,237
Ensembl chr14:18,851,954...18,853,315
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO MGI:2146995|MGI:96055 (MGI:5494903|PMID:23509158) RGD PMID:23509158 MGI:5494903 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IEA
ISO
GO_REF:0000107
MGI:2146995|MGI:99511 (MGI:5494903|PMID:23509158)
Ensembl
RGD
PMID:23509158 GO_REF:0000107, MGI:5494903 NCBI chr 4:157,239,141...157,263,890
Ensembl chr 4:157,239,142...157,263,890
JBrowse link
G Srf serum response factor ISO MGI:2176073|MGI:3046779|MGI:3522206|MGI:3764698 (MGI:4834086|PMID:20525922), (MGI:4848276|PMID:20709909) RGD PMID:20525922, PMID:20709909 MGI:4834086, MGI:4848276 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor ISO MGI:1858004|MGI:2450743 (MGI:3808106|PMID:16763211) RGD PMID:16763211 MGI:3808106 NCBI chr 5:133,864,401...133,878,604
Ensembl chr 5:133,864,798...133,878,830
JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes IEA
ISO
GO_REF:0000107
MGI:1856687 (MGI:2450053|PMID:12538872)
Ensembl
RGD
PMID:12538872 GO_REF:0000107, MGI:2450053 NCBI chr12:38,459,816...38,482,903
Ensembl chr12:38,459,832...38,484,512
JBrowse link
G Wdr1 WD repeat domain 1 ISO (MGI:3784948|PMID:17515402) RGD PMID:17515402 MGI:3784948 NCBI chr14:76,990,014...77,023,739
Ensembl chr14:76,989,919...77,023,726
JBrowse link
G Zfp385a zinc finger protein 385A ISO MGI:3510440 (MGI:3505817|PMID:11927637) RGD PMID:11927637 MGI:3505817 NCBI chr 7:144,939,616...144,966,364
Ensembl chr 7:144,939,619...144,966,370
JBrowse link
G Zfpm1 zinc finger protein, multitype 1 ISO UniProtKB:P15976 (PMID:11675338) RGD PMID:11675338 NCBI chr19:55,094,585...55,150,994
Ensembl chr19:55,094,585...55,150,686
JBrowse link
positive regulation of platelet formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpl MPL proto-oncogene, thrombopoietin receptor IMP RGD PMID:10606160 RGD:10449003 NCBI chr 5:137,268,412...137,282,032
Ensembl chr 5:137,269,480...137,281,298
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO (MGI:6414739|PMID:32103174) RGD PMID:32103174 MGI:6414739 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure formation involved in morphogenesis 1214
        platelet formation 22
          negative regulation of platelet formation 0
          positive regulation of platelet formation 2
          regulation of platelet formation + 2
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            immune system development 1074
              hematopoietic or lymphoid organ development 1009
                hemopoiesis 957
                  myeloid cell differentiation 433
                    platelet formation 22
                      negative regulation of platelet formation 0
                      positive regulation of platelet formation 2
                      regulation of platelet formation + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.