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ONTOLOGY REPORT - ANNOTATIONS


Term:chromosome condensation
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Accession:GO:0030261 term browser browse the term
Definition:The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
Synonyms:exact_synonym: eukaryotic chromosome condensation;   nuclear chromosome condensation
 broad_synonym: DNA condensation
 alt_id: GO:0000068


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chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK1 cyclin dependent kinase 1 ISO RGD PMID:15695611 RGD:2301352 NCBI chr10:57,314,692...57,331,261
Ensembl chr10:59,647,993...59,664,434
JBrowse link
G SMC5 structural maintenance of chromosomes 5 ISO (MGI:MGI:5882483|PMID:26919979) MGI PMID:26919979 MGI:MGI:5882483 NCBI chr 9:54,446,863...54,543,249 JBrowse link
G TOP2A DNA topoisomerase II alpha ISO (MGI:MGI:2158879|PMID:11835580) MGI PMID:11835580 MGI:MGI:2158879 NCBI chr17:16,872,169...16,901,605
Ensembl chr17:17,097,778...17,126,207
JBrowse link
apoptotic chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACIN1 apoptotic chromatin condensation inducer 1 ISO (PMID:10490026) UniProtKB PMID:10490026 NCBI chr14:3,878,426...3,915,802
Ensembl chr14:21,975,370...22,012,092
JBrowse link
G DFFB DNA fragmentation factor subunit beta ISO (PMID:10959840) UniProtKB PMID:10959840 NCBI chr 1:2,529,733...2,559,490
Ensembl chr 1:3,649,729...3,676,896
JBrowse link
G ERN2 endoplasmic reticulum to nucleus signaling 2 ISO (PMID:11175748) UniProtKB PMID:11175748 NCBI chr16:14,397,697...14,420,618
Ensembl chr16:23,940,716...23,963,894
JBrowse link
G LOC100967334 G-protein coupled estrogen receptor 1 ISO PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr 7:1,245,873...1,251,915 JBrowse link
G TOP2A DNA topoisomerase II alpha ISO (PMID:10959840) UniProtKB PMID:10959840 NCBI chr17:16,872,169...16,901,605
Ensembl chr17:17,097,778...17,126,207
JBrowse link
histone H3-S10 phosphorylation involved in chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNB1 cyclin B1 ISO (MGI:MGI:5494393|PMID:22053081) MGI PMID:22053081 MGI:MGI:5494393 NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332
JBrowse link
meiotic chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MASTL microtubule associated serine/threonine kinase like ISO (PMID:23843240) AgBase PMID:23843240 NCBI chr10:27,264,475...27,296,085
Ensembl chr10:27,626,892...27,658,180
JBrowse link
G NCAPH non-SMC condensin I complex subunit H ISO (MGI:MGI:5317363|PMID:21795393)
(MGI:MGI:5784807|PMID:25961503)
MGI PMID:21795393, PMID:25961503 MGI:MGI:5317363, MGI:MGI:5784807 NCBI chr2A:102,939,357...102,980,091
Ensembl chr2A:97,258,412...97,299,906
JBrowse link
G NCAPH2 non-SMC condensin II complex subunit H2 ISO (MGI:MGI:5784807|PMID:25961503) MGI PMID:25961503 MGI:MGI:5784807 NCBI chr22:30,754,994...30,771,103
Ensembl chr22:49,873,223...49,881,027
JBrowse link
G SMC2 structural maintenance of chromosomes 2 ISO (MGI:MGI:5317363|PMID:21795393) MGI PMID:21795393 MGI:MGI:5317363 NCBI chr 9:75,273,163...75,323,486
Ensembl chr 9:103,402,967...103,449,949
JBrowse link
G SMC4 structural maintenance of chromosomes 4 ISO (MGI:MGI:5317363|PMID:21795393) MGI PMID:21795393 MGI:MGI:5317363 NCBI chr 3:157,421,548...157,456,593
Ensembl chr 3:165,469,567...165,504,967
JBrowse link
mitotic chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP8 A-kinase anchoring protein 8 ISO (MGI:MGI:3512088|PMID:12082153) MGI PMID:12082153 MGI:MGI:3512088 NCBI chr19:14,888,201...14,912,739
Ensembl chr19:15,872,536...15,897,661
JBrowse link
G AKAP8L A-kinase anchoring protein 8 like ISO (PMID:11034899) UniProtKB PMID:11034899 NCBI chr19:14,912,960...14,950,479
Ensembl chr19:15,897,969...15,936,486
JBrowse link
G CHMP1A charged multivesicular body protein 1A ISO (PMID:11559747) UniProtKB PMID:11559747 NCBI chr16:70,398,021...70,411,383
Ensembl chr16:90,003,892...90,017,653
JBrowse link
G NCAPD2 non-SMC condensin I complex subunit D2 ISO (PMID:27737959)
(PMID:11136719)
UniProt
UniProtKB
PMID:11136719, PMID:27737959 NCBI chr12:6,623,568...6,662,741
Ensembl chr12:6,540,750...6,580,206
JBrowse link
G NCAPD3 non-SMC condensin II complex subunit D3 ISO (PMID:14532007)
(PMID:27737959)
UniProtKB
UniProt
PMID:14532007, PMID:27737959 NCBI chr11:129,005,365...129,078,581
Ensembl chr11:132,865,349...132,935,590
JBrowse link
G NCAPG non-SMC condensin I complex subunit G ISO (PMID:11136719) UniProtKB PMID:11136719 NCBI chr 4:12,232,614...12,265,320
Ensembl chr 4:17,524,826...17,571,798
JBrowse link
G NCAPH non-SMC condensin I complex subunit H ISO (PMID:11136719), (PMID:11694586)
(PMID:27737959)
UniProtKB
UniProt
PMID:11136719, PMID:11694586, PMID:27737959 NCBI chr2A:102,939,357...102,980,091
Ensembl chr2A:97,258,412...97,299,906
JBrowse link
G NCAPH2 non-SMC condensin II complex subunit H2 ISO (MGI:MGI:5905517|PMID:27737959) UniProt PMID:27737959 MGI:MGI:5905517 NCBI chr22:30,754,994...30,771,103
Ensembl chr22:49,873,223...49,881,027
JBrowse link
G NUSAP1 nucleolar and spindle associated protein 1 ISO (PMID:12963707) MGI PMID:12963707 NCBI chr15:20,273,953...20,322,512 JBrowse link
G PHF13 PHD finger protein 13 ISO (PMID:19638409) UniProtKB PMID:19638409 NCBI chr 1:5,377,740...5,388,024
Ensembl chr 1:6,631,621...6,639,972
JBrowse link
G SMC2 structural maintenance of chromosomes 2 ISO (PMID:11136719) UniProtKB PMID:11136719 NCBI chr 9:75,273,163...75,323,486
Ensembl chr 9:103,402,967...103,449,949
JBrowse link
G SMC4 structural maintenance of chromosomes 4 ISO (PMID:11136719) UniProtKB PMID:11136719 NCBI chr 3:157,421,548...157,456,593
Ensembl chr 3:165,469,567...165,504,967
JBrowse link
G TTN titin ISO (PMID:9548712) BHF-UCL PMID:9548712 NCBI chr2B:65,783,512...66,064,618 JBrowse link
negative regulation of chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100970414 histone H3.3A ISO (MGI:MGI:5502235|PMID:23903189) MGI PMID:23903189 MGI:MGI:5502235 NCBI chr 1:201,523,670...201,533,005
Ensembl chr 1:206,520,109...206,529,447
JBrowse link
G LOC100988671 histone H3.3A ISO (MGI:MGI:5502235|PMID:23903189) MGI PMID:23903189 MGI:MGI:5502235 NCBI chr17:69,728,165...69,730,519
Ensembl chr17:75,277,614...75,281,106
JBrowse link
regulation of chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNB1 cyclin B1 ISO positive regulation RGD PMID:15291744 RGD:1578405 NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332
JBrowse link
G MCPH1 microcephalin 1 ISO (MGI:MGI:4437500|PMID:20169082) MGI PMID:20169082 MGI:MGI:4437500 NCBI chr 8:624,877...877,839
Ensembl chr 8:6,409,072...6,646,394
JBrowse link
G WAPL WAPL cohesin release factor ISO (MGI:MGI:5544860|PMID:23975099) MGI PMID:23975099 MGI:MGI:5544860 NCBI chr10:82,862,852...82,953,284
Ensembl chr10:86,422,170...86,512,207
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 12524
    cellular process 11624
      cellular component organization or biogenesis 4978
        cellular component organization 4898
          organelle organization 3021
            chromosome organization 877
              DNA conformation change 167
                DNA packaging 133
                  chromosome condensation 26
                    apoptotic chromosome condensation 5
                    histone H3-S10 phosphorylation involved in chromosome condensation 1
                    meiotic chromosome condensation 5
                    mitotic chromosome condensation + 13
                    negative regulation of chromosome condensation + 2
                    nonrepetitive DNA condensation 0
                    positive regulation of chromosome condensation + 0
                    rDNA condensation 0
                    regulation of chromosome condensation + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.