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ONTOLOGY REPORT - ANNOTATIONS


Term:chromosome condensation
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Accession:GO:0030261 term browser browse the term
Definition:The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
Synonyms:exact_synonym: eukaryotic chromosome condensation;   nuclear chromosome condensation
 broad_synonym: DNA condensation
 alt_id: GO:0000068


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chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk1 cyclin dependent kinase 1 ISO RGD PMID:15695611 RGD:2301352 NCBI chrNW_004955425:14,210,681...14,226,474 JBrowse link
G Smc5 structural maintenance of chromosomes 5 ISO (MGI:MGI:5882483|PMID:26919979) MGI PMID:26919979 MGI:MGI:5882483 NCBI chrNW_004955434:2,742,276...2,848,384 JBrowse link
G Top2a DNA topoisomerase II alpha ISO (MGI:MGI:2158879|PMID:11835580) MGI PMID:11835580 MGI:MGI:2158879 NCBI chrNW_004955451:14,928,273...14,964,855 JBrowse link
apoptotic chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acin1 apoptotic chromatin condensation inducer 1 ISO (PMID:10490026) UniProtKB PMID:10490026 NCBI chrNW_004955409:37,206,675...37,246,851 JBrowse link
G Dffb DNA fragmentation factor subunit beta ISO (PMID:10959840) UniProtKB PMID:10959840 NCBI chrNW_004955486:7,836,013...7,849,875 JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 ISO (PMID:11175748) UniProtKB PMID:11175748 NCBI chrNW_004955493:2,217,187...2,233,920 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 ISO PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chrNW_004955460:8,790,798...8,794,902 JBrowse link
G Top2a DNA topoisomerase II alpha ISO (PMID:10959840) UniProtKB PMID:10959840 NCBI chrNW_004955451:14,928,273...14,964,855 JBrowse link
histone H3-S10 phosphorylation involved in chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 ISO (MGI:MGI:5494393|PMID:22053081) MGI PMID:22053081 MGI:MGI:5494393 NCBI chrNW_004955446:140,661...149,500 JBrowse link
meiotic chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mastl microtubule associated serine/threonine kinase like ISO (PMID:23843240) AgBase PMID:23843240 NCBI chrNW_004955429:2,591,173...2,617,084 JBrowse link
G Ncaph non-SMC condensin I complex subunit H ISO (MGI:MGI:5317363|PMID:21795393)
(MGI:MGI:5784807|PMID:25961503)
MGI PMID:21795393, PMID:25961503 MGI:MGI:5317363, MGI:MGI:5784807 NCBI chrNW_004955470:3,878,896...3,909,087 JBrowse link
G Ncaph2 non-SMC condensin II complex subunit H2 ISO (MGI:MGI:5784807|PMID:25961503) MGI PMID:25961503 MGI:MGI:5784807 NCBI chrNW_004955413:33,492,348...33,503,804 JBrowse link
G Smc2 structural maintenance of chromosomes 2 ISO (MGI:MGI:5317363|PMID:21795393) MGI PMID:21795393 MGI:MGI:5317363 NCBI chrNW_004955419:22,245,843...22,294,508 JBrowse link
G Smc4 structural maintenance of chromosomes 4 ISO (MGI:MGI:5317363|PMID:21795393) MGI PMID:21795393 MGI:MGI:5317363 NCBI chrNW_004955448:10,926,653...10,960,624 JBrowse link
mitotic chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap8 A-kinase anchoring protein 8 ISO (MGI:MGI:3512088|PMID:12082153) MGI PMID:12082153 MGI:MGI:3512088 NCBI chrNW_004955495:7,874,655...7,893,209 JBrowse link
G Akap8l A-kinase anchoring protein 8 like ISO (PMID:11034899) UniProtKB PMID:11034899 NCBI chrNW_004955495:7,839,339...7,874,432 JBrowse link
G Cdca5 cell division cycle associated 5 ISO (PMID:15837422) UniProtKB PMID:15837422 NCBI chrNW_004955422:20,114,565...20,129,679 JBrowse link
G Chmp1a charged multivesicular body protein 1A ISO (PMID:11559747) UniProtKB PMID:11559747 NCBI chrNW_004955541:3,216,972...3,223,636 JBrowse link
G Ncapd2 non-SMC condensin I complex subunit D2 ISO (PMID:27737959)
(PMID:11136719)
UniProt
UniProtKB
PMID:11136719, PMID:27737959 NCBI chrNW_004955413:4,136,492...4,160,550 JBrowse link
G Ncapd3 non-SMC condensin II complex subunit D3 ISO (PMID:27737959)
(PMID:14532007)
UniProt
UniProtKB
PMID:14532007, PMID:27737959 NCBI chrNW_004955412:34,967,464...35,035,103 JBrowse link
G Ncapg non-SMC condensin I complex subunit G ISO (PMID:11136719) UniProtKB PMID:11136719 NCBI chrNW_004955480:6,399,891...6,430,617 JBrowse link
G Ncaph non-SMC condensin I complex subunit H ISO (PMID:27737959)
(PMID:11136719), (PMID:11694586)
UniProt
UniProtKB
PMID:11136719, PMID:11694586, PMID:27737959 NCBI chrNW_004955470:3,878,896...3,909,087 JBrowse link
G Ncaph2 non-SMC condensin II complex subunit H2 ISO (MGI:MGI:5905517|PMID:27737959) UniProt PMID:27737959 MGI:MGI:5905517 NCBI chrNW_004955413:33,492,348...33,503,804 JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 ISO (PMID:12963707) MGI PMID:12963707 NCBI chrNW_004955416:8,178,493...8,208,336 JBrowse link
G Phf13 PHD finger protein 13 ISO (PMID:19638409) UniProtKB PMID:19638409 NCBI chrNW_004955486:6,018,614...6,025,473 JBrowse link
G Smc2 structural maintenance of chromosomes 2 ISO (PMID:11136719) UniProtKB PMID:11136719 NCBI chrNW_004955419:22,245,843...22,294,508 JBrowse link
G Smc4 structural maintenance of chromosomes 4 ISO (PMID:11136719) UniProtKB PMID:11136719 NCBI chrNW_004955448:10,926,653...10,960,624 JBrowse link
G Ttn titin ISO (PMID:9548712) BHF-UCL PMID:9548712 NCBI chrNW_004955403:18,057,344...18,328,389 JBrowse link
negative regulation of chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H3f3a H3 histone, family 3A ISO (MGI:MGI:5502235|PMID:23903189) MGI PMID:23903189 MGI:MGI:5502235 NCBI chrNW_004955489:269,900...278,398 JBrowse link
G H3f3b H3 histone, family 3B ISO (MGI:MGI:5502235|PMID:23903189) MGI PMID:23903189 MGI:MGI:5502235 NCBI chrNW_004955506:6,475,336...6,478,781 JBrowse link
regulation of chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 ISO positive regulation RGD PMID:15291744 RGD:1578405 NCBI chrNW_004955446:140,661...149,500 JBrowse link
G Mcph1 microcephalin 1 ISO (MGI:MGI:4437500|PMID:20169082) MGI PMID:20169082 MGI:MGI:4437500 NCBI chrNW_004955403:54,143,454...54,273,201 JBrowse link
G Wapl WAPL cohesin release factor ISO (MGI:MGI:5544860|PMID:23975099) MGI PMID:23975099 MGI:MGI:5544860 NCBI chrNW_004955510:5,596,622...5,674,221 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 11857
    cellular process 11058
      cellular component organization or biogenesis 4836
        cellular component organization 4756
          organelle organization 2935
            chromosome organization 843
              DNA conformation change 154
                DNA packaging 120
                  chromosome condensation 27
                    apoptotic chromosome condensation 5
                    histone H3-S10 phosphorylation involved in chromosome condensation 1
                    meiotic chromosome condensation 5
                    mitotic chromosome condensation + 14
                    negative regulation of chromosome condensation + 2
                    nonrepetitive DNA condensation 0
                    positive regulation of chromosome condensation + 0
                    rDNA condensation 0
                    regulation of chromosome condensation + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.