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ONTOLOGY REPORT - ANNOTATIONS


Term:chromosome condensation
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Accession:GO:0030261 term browser browse the term
Definition:The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
Synonyms:exact_synonym: eukaryotic chromosome condensation;   nuclear chromosome condensation
 broad_synonym: DNA condensation
 alt_id: GO:0000068


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chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BANF2 BANF family member 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr24:5,274,524...5,308,606
Ensembl chr24:5,274,553...5,307,433
JBrowse link
G CDK1 cyclin dependent kinase 1 ISO RGD PMID:15695611 RGD:2301352 NCBI chr 4:12,884,106...12,899,203
Ensembl chr 4:12,883,385...12,899,197
JBrowse link
G H1-2 H1.2 linker histone, cluster member IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr35:24,009,304...24,011,602 JBrowse link
G H1-4 H1.4 linker histone, cluster member IBA (PMID:21873635) GO_Central PMID:21873635
G H1-6 H1.6 linker histone, cluster member IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr35:24,046,374...24,065,892
Ensembl chr35:24,044,188...24,047,810
JBrowse link
G H1-8 H1.8 linker histone IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:5,614,822...5,619,136
Ensembl chr20:5,617,001...5,624,352
JBrowse link
G H1-9 H1.9 linker histone IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr 9:26,169,774...26,170,316 JBrowse link
G SMC5 structural maintenance of chromosomes 5 ISO (MGI:MGI:5882483|PMID:26919979) MGI PMID:26919979 MGI:MGI:5882483 NCBI chr 1:87,192,988...87,285,678
Ensembl chr 1:87,194,867...87,285,606
JBrowse link
G TOP2A DNA topoisomerase II alpha ISO (MGI:MGI:2158879|PMID:11835580) MGI PMID:11835580 MGI:MGI:2158879 NCBI chr 9:22,207,501...22,237,497
Ensembl chr 9:22,207,638...22,237,496
JBrowse link
apoptotic chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACIN1 apoptotic chromatin condensation inducer 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:3,370,469...3,405,710
Ensembl chr 8:3,371,004...3,405,682
JBrowse link
G DFFB DNA fragmentation factor subunit beta ISO (PMID:10959840) UniProtKB PMID:10959840 NCBI chr 5:58,340,183...58,355,353
Ensembl chr 5:58,339,634...58,354,326
JBrowse link
G ERN2 endoplasmic reticulum to nucleus signaling 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:22,150,275...22,165,382
Ensembl chr 6:22,150,307...22,165,614
JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 ISO PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr 6:15,792,072...15,796,922
Ensembl chr 6:15,792,897...15,794,051
JBrowse link
G TOP2A DNA topoisomerase II alpha IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:22,207,501...22,237,497
Ensembl chr 9:22,207,638...22,237,496
JBrowse link
histone H3-S10 phosphorylation involved in chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNB1 cyclin B1 ISO (MGI:MGI:5494393|PMID:22053081) MGI PMID:22053081 MGI:MGI:5494393 NCBI chr 2:54,256,957...54,264,749 JBrowse link
meiotic chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INCENP inner centromere protein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:54,361,376...54,384,649
Ensembl chr18:54,361,378...54,384,641
JBrowse link
G MASTL microtubule associated serine/threonine kinase like ISO (PMID:23843240) AgBase PMID:23843240 NCBI chr 2:6,829,309...6,863,876
Ensembl chr 2:6,830,168...6,863,568
JBrowse link
G NCAPD2 non-SMC condensin I complex subunit D2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr27:38,475,145...38,497,818
Ensembl chr27:38,475,155...38,496,312
JBrowse link
G NCAPD3 non-SMC condensin II complex subunit D3 IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000104 NCBI chr 5:1,021,588...1,081,846
Ensembl chr 5:1,020,690...1,081,446
JBrowse link
G NCAPH non-SMC condensin I complex subunit H IEA Ensembl GO_REF:0000107 NCBI chr17:34,428,886...34,463,140
Ensembl chr17:34,420,060...34,462,666
JBrowse link
G NCAPH2 non-SMC condensin II complex subunit H2 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr10:16,790,137...16,801,851
Ensembl chr10:16,741,761...16,801,824
JBrowse link
G SMC2 structural maintenance of chromosomes 2 IEA Ensembl GO_REF:0000107 NCBI chr11:60,091,728...60,155,295
Ensembl chr11:60,091,457...60,151,442
JBrowse link
G SMC4 structural maintenance of chromosomes 4 IEA Ensembl GO_REF:0000107 NCBI chr34:26,455,630...26,495,392
Ensembl chr34:26,456,142...26,494,725
JBrowse link
mitotic chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP8 A-kinase anchoring protein 8 IEA Ensembl GO_REF:0000107 NCBI chr20:46,800,917...46,817,397
Ensembl chr20:46,800,872...46,817,397
JBrowse link
G AKAP8L A-kinase anchoring protein 8 like ISO (PMID:11034899) UniProtKB PMID:11034899 NCBI chr20:46,773,585...46,800,544 JBrowse link
G CDCA5 cell division cycle associated 5 IEA Ensembl GO_REF:0000107 NCBI chr18:52,115,081...52,129,223
Ensembl chr18:52,115,203...52,120,817
JBrowse link
G CHMP1A charged multivesicular body protein 1A IEA Ensembl GO_REF:0000107 NCBI chr 5:63,897,544...63,906,515
Ensembl chr 5:63,897,594...63,905,550
JBrowse link
G NCAPD2 non-SMC condensin I complex subunit D2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr27:38,475,145...38,497,818
Ensembl chr27:38,475,155...38,496,312
JBrowse link
G NCAPD3 non-SMC condensin II complex subunit D3 IEA
IBA
(PMID:21873635) Ensembl
InterPro
GO_Central
PMID:21873635 GO_REF:0000002, GO_REF:0000107 NCBI chr 5:1,021,588...1,081,846
Ensembl chr 5:1,020,690...1,081,446
JBrowse link
G NCAPG non-SMC condensin I complex subunit G IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 3:91,279,800...91,322,679
Ensembl chr 3:91,281,077...91,322,803
JBrowse link
G NCAPH non-SMC condensin I complex subunit H IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr17:34,428,886...34,463,140
Ensembl chr17:34,420,060...34,462,666
JBrowse link
G NCAPH2 non-SMC condensin II complex subunit H2 IEA Ensembl GO_REF:0000107 NCBI chr10:16,790,137...16,801,851
Ensembl chr10:16,741,761...16,801,824
JBrowse link
G NIPBL NIPBL cohesin loading factor IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:71,583,118...71,780,986
Ensembl chr 4:71,583,732...71,780,852
JBrowse link
G NUSAP1 nucleolar and spindle associated protein 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr30:8,358,737...8,435,039
Ensembl chr30:8,396,399...8,434,179
JBrowse link
G PHF13 PHD finger protein 13 ISO (PMID:19638409) UniProtKB PMID:19638409 NCBI chr 5:60,434,218...60,441,930
Ensembl chr 5:60,433,328...60,439,672
JBrowse link
G SMC2 structural maintenance of chromosomes 2 IEA Ensembl GO_REF:0000107 NCBI chr11:60,091,728...60,155,295
Ensembl chr11:60,091,457...60,151,442
JBrowse link
G SMC4 structural maintenance of chromosomes 4 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr34:26,455,630...26,495,392
Ensembl chr34:26,456,142...26,494,725
JBrowse link
G TTN titin ISO (PMID:9548712) BHF-UCL PMID:9548712 NCBI chr36:22,146,870...22,417,858
Ensembl chr36:22,147,824...22,417,826
JBrowse link
negative regulation of chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H3-3A H3.3 histone A IEA Ensembl GO_REF:0000107 NCBI chr 7:38,797,168...38,805,417
Ensembl chr 7:38,797,448...38,805,416
JBrowse link
G H3-3B H3.3 histone B IEA Ensembl GO_REF:0000107 NCBI chr 9:4,805,655...4,808,076
Ensembl chr 9:4,805,650...4,833,503
JBrowse link
rDNA condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NIPBL NIPBL cohesin loading factor IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:71,583,118...71,780,986
Ensembl chr 4:71,583,732...71,780,852
JBrowse link
regulation of chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNB1 cyclin B1 ISO positive regulation RGD PMID:15291744 RGD:1578405 NCBI chr 2:54,256,957...54,264,749 JBrowse link
G MCPH1 microcephalin 1 IEA Ensembl GO_REF:0000107 NCBI chr16:58,306,761...58,529,090
Ensembl chr16:58,295,280...58,529,433
JBrowse link
G WAPL WAPL cohesin release factor IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 4:34,219,644...34,297,456
Ensembl chr 4:34,219,645...34,302,839
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 16162
    cellular process 15442
      cellular component organization or biogenesis 6021
        cellular component organization 5852
          organelle organization 3698
            chromosome organization 1110
              DNA conformation change 266
                DNA packaging 181
                  chromosome condensation 35
                    apoptotic chromosome condensation 5
                    histone H3-S10 phosphorylation involved in chromosome condensation 1
                    meiotic chromosome condensation 8
                    mitotic chromosome condensation + 15
                    negative regulation of chromosome condensation + 2
                    nonrepetitive DNA condensation 0
                    positive regulation of chromosome condensation + 0
                    rDNA condensation 1
                    regulation of chromosome condensation + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.