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ONTOLOGY REPORT - ANNOTATIONS


Term:chromosome condensation
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Accession:GO:0030261 term browser browse the term
Definition:The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
Synonyms:exact_synonym: eukaryotic chromosome condensation;   nuclear chromosome condensation
 broad_synonym: DNA condensation
 alt_id: GO:0000068


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chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk1 cyclin dependent kinase 1 ISO RGD PMID:15695611 RGD:2301352 NCBI chrNW_004936614:2,300,682...2,313,611 JBrowse link
G Smc5 structural maintenance of chromosomes 5 ISO (MGI:MGI:5882483|PMID:26919979) MGI PMID:26919979 MGI:MGI:5882483 NCBI chrNW_004936503:6,388,556...6,483,293 JBrowse link
G Top2a DNA topoisomerase II alpha ISO (MGI:MGI:2158879|PMID:11835580) MGI PMID:11835580 MGI:MGI:2158879 NCBI chrNW_004936490:15,441,463...15,465,692 JBrowse link
apoptotic chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acin1 apoptotic chromatin condensation inducer 1 ISO (PMID:10490026) UniProtKB PMID:10490026 NCBI chrNW_004936722:1,252,083...1,264,018 JBrowse link
G Dffb DNA fragmentation factor subunit beta ISO (PMID:10959840) UniProtKB PMID:10959840 NCBI chrNW_004936737:79,789...96,140 JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 ISO (PMID:11175748) UniProtKB PMID:11175748 NCBI chrNW_004936501:8,332,507...8,350,176 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 ISO PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chrNW_004936754:1,288,891...1,293,555 JBrowse link
G Top2a DNA topoisomerase II alpha ISO (PMID:10959840) UniProtKB PMID:10959840 NCBI chrNW_004936490:15,441,463...15,465,692 JBrowse link
histone H3-S10 phosphorylation involved in chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 ISO (MGI:MGI:5494393|PMID:22053081) MGI PMID:22053081 MGI:MGI:5494393 NCBI chrNW_004936480:400,287...407,677 JBrowse link
meiotic chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mastl microtubule associated serine/threonine kinase like ISO (PMID:23843240) AgBase PMID:23843240 NCBI chrNW_004936484:2,276,463...2,306,119 JBrowse link
G Ncaph non-SMC condensin I complex subunit H ISO (MGI:MGI:5317363|PMID:21795393)
(MGI:MGI:5784807|PMID:25961503)
MGI PMID:21795393, PMID:25961503 MGI:MGI:5317363, MGI:MGI:5784807 NCBI chrNW_004936744:440,958...468,964 JBrowse link
G Ncaph2 non-SMC condensin II complex subunit H2 ISO (MGI:MGI:5784807|PMID:25961503) MGI PMID:25961503 MGI:MGI:5784807 NCBI chrNW_004936629:320,885...327,290 JBrowse link
G Smc2 structural maintenance of chromosomes 2 ISO (MGI:MGI:5317363|PMID:21795393) MGI PMID:21795393 MGI:MGI:5317363 NCBI chrNW_004936793:909,663...958,883 JBrowse link
G Smc4 structural maintenance of chromosomes 4 ISO (MGI:MGI:5317363|PMID:21795393) MGI PMID:21795393 MGI:MGI:5317363 NCBI chrNW_004936708:362,605...395,217 JBrowse link
mitotic chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap8 A-kinase anchoring protein 8 ISO (MGI:MGI:3512088|PMID:12082153) MGI PMID:12082153 MGI:MGI:3512088 NCBI chrNW_004936596:5,123,988...5,142,326 JBrowse link
G Akap8l A-kinase anchoring protein 8 like ISO (PMID:11034899) UniProtKB PMID:11034899 NCBI chrNW_004936596:5,088,260...5,123,735 JBrowse link
G Cdca5 cell division cycle associated 5 ISO (PMID:15837422) UniProtKB PMID:15837422 NCBI chrNW_004936599:4,285,007...4,291,875 JBrowse link
G Chmp1a charged multivesicular body protein 1A ISO (PMID:11559747) UniProtKB PMID:11559747 NCBI chrNW_004936641:366,563...376,303 JBrowse link
G Ncapd2 non-SMC condensin I complex subunit D2 ISO (PMID:11136719)
(PMID:27737959)
UniProtKB
UniProt
PMID:11136719, PMID:27737959 NCBI chrNW_004936709:1,250,442...1,275,823 JBrowse link
G Ncapd3 non-SMC condensin II complex subunit D3 ISO (PMID:14532007)
(PMID:27737959)
UniProtKB
UniProt
PMID:14532007, PMID:27737959 NCBI chrNW_004936684:1,618,271...1,687,905 JBrowse link
G Ncapg non-SMC condensin I complex subunit G ISO (PMID:11136719) UniProtKB PMID:11136719 NCBI chrNW_004936477:10,408,347...10,445,361 JBrowse link
G Ncaph non-SMC condensin I complex subunit H ISO (PMID:27737959)
(PMID:11136719), (PMID:11694586)
UniProt
UniProtKB
PMID:11136719, PMID:11694586, PMID:27737959 NCBI chrNW_004936744:440,958...468,964 JBrowse link
G Ncaph2 non-SMC condensin II complex subunit H2 ISO (MGI:MGI:5905517|PMID:27737959) UniProt PMID:27737959 MGI:MGI:5905517 NCBI chrNW_004936629:320,885...327,290 JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 ISO (PMID:12963707) MGI PMID:12963707 NCBI chrNW_004936471:4,705,757...4,732,446 JBrowse link
G Phf13 PHD finger protein 13 ISO (PMID:19638409) UniProtKB PMID:19638409 NCBI chrNW_004936623:1,364,422...1,372,226 JBrowse link
G Smc2 structural maintenance of chromosomes 2 ISO (PMID:11136719) UniProtKB PMID:11136719 NCBI chrNW_004936793:909,663...958,883 JBrowse link
G Smc4 structural maintenance of chromosomes 4 ISO (PMID:11136719) UniProtKB PMID:11136719 NCBI chrNW_004936708:362,605...395,217 JBrowse link
G Ttn titin ISO (PMID:9548712) BHF-UCL PMID:9548712 NCBI chrNW_004936509:7,733,426...7,999,503 JBrowse link
negative regulation of chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101963041 histone H3.3 ISO (MGI:MGI:5502235|PMID:23903189) MGI PMID:23903189 MGI:MGI:5502235 NCBI chrNW_004936526:2,835,002...2,842,328 JBrowse link
G LOC101963257 histone H3.3 ISO (MGI:MGI:5502235|PMID:23903189) MGI PMID:23903189 MGI:MGI:5502235 NCBI chrNW_004936594:959,493...961,703 JBrowse link
regulation of chromosome condensation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 ISO positive regulation RGD PMID:15291744 RGD:1578405 NCBI chrNW_004936480:400,287...407,677 JBrowse link
G Mcph1 microcephalin 1 ISO (MGI:MGI:4437500|PMID:20169082) MGI PMID:20169082 MGI:MGI:4437500 NCBI chrNW_004936615:4,386,667...4,580,720 JBrowse link
G Wapl WAPL cohesin release factor ISO (MGI:MGI:5544860|PMID:23975099) MGI PMID:23975099 MGI:MGI:5544860 NCBI chrNW_004936804:354,201...431,655 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 11962
    cellular process 11135
      cellular component organization or biogenesis 4887
        cellular component organization 4809
          organelle organization 2971
            chromosome organization 864
              DNA conformation change 160
                DNA packaging 125
                  chromosome condensation 27
                    apoptotic chromosome condensation 5
                    histone H3-S10 phosphorylation involved in chromosome condensation 1
                    meiotic chromosome condensation 5
                    mitotic chromosome condensation + 14
                    negative regulation of chromosome condensation + 2
                    nonrepetitive DNA condensation 0
                    positive regulation of chromosome condensation + 0
                    rDNA condensation 0
                    regulation of chromosome condensation + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.