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ONTOLOGY REPORT - ANNOTATIONS


Term:T-tubule
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Accession:GO:0030315 term browser browse the term
Definition:Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
Synonyms:exact_synonym: transverse tubule
 related_synonym: triad
 xref: Wikipedia:T-tubule


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T-tubule term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc9 ATP binding cassette subfamily C member 9 JBrowse link 4 176,806,098 176,928,540 RGD:1598637
G Abcc9_v2 ATP binding cassette subfamily C member 9, variant 2 RGD:1598649
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:5688343
G Adra1b adrenoceptor alpha 1B JBrowse link 10 29,392,762 29,450,644 RGD:5688343
G Ahnak AHNAK nucleoprotein JBrowse link 1 225,184,883 225,429,638 RGD:1624291
G Ahnak2 AHNAK nucleoprotein 2 JBrowse link 6 137,335,273 137,380,219 RGD:1624291
G Akap6 A-kinase anchoring protein 6 JBrowse link 6 73,553,111 73,991,992 RGD:8553491
G Akap7 A-kinase anchoring protein 7 JBrowse link 1 21,129,213 21,263,850 RGD:1304018
G Ank2 ankyrin 2 JBrowse link 2 231,224,643 231,522,655 RGD:1624291
G Ank3 ankyrin 3 JBrowse link 20 19,948,767 20,480,628 RGD:6484228
G Aqp4 aquaporin 4 JBrowse link 18 6,766,009 6,782,757 RGD:5490121
G Asb15 ankyrin repeat and SOCS box containing 15 JBrowse link 4 51,598,815 51,642,276 RGD:13792537
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:1624291
RGD:6903343
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:6903343
RGD:1624291
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 JBrowse link 13 82,737,161 82,757,681 RGD:1624291
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 13 50,091,644 50,153,808 RGD:1624291
G Bin1 bridging integrator 1 JBrowse link 18 25,163,575 25,222,139 RGD:8553847
RGD:1624291
RGD:1600115
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1304018
RGD:1624291
RGD:8554533
G Cacna1s calcium voltage-gated channel subunit alpha1 S JBrowse link 13 52,889,570 52,964,558 RGD:1600115
RGD:1624291
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 JBrowse link 4 15,706,974 16,130,848 RGD:1624291
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 JBrowse link 10 85,954,138 85,974,764 RGD:1624291
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 JBrowse link 10 95,921,479 95,934,170 RGD:1600115
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:1624291
G Capn3 calpain 3 JBrowse link 3 112,227,486 112,278,408 RGD:8553509
G Casq1 calsequestrin 1 JBrowse link 13 90,592,676 90,602,365 RGD:2313244
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1599531
RGD:1624291
RGD:8553487
G Cdh2 cadherin 2 JBrowse link 18 8,146,971 8,366,037 RGD:6484228
G Cltc clathrin heavy chain JBrowse link 10 74,014,560 74,070,578 RGD:2303181
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1581466
G Dysf dysferlin JBrowse link 4 115,700,942 115,901,873 RGD:1624291
RGD:13792537
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:1581834
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1601102
G Ezr ezrin JBrowse link 1 47,287,872 47,331,412 RGD:7207798
G Fxyd1 FXYD domain-containing ion transport regulator 1 JBrowse link 1 89,484,197 89,488,279 RGD:9685469
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:11041118
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:10046017
RGD:1624291
G Kcnd2 potassium voltage-gated channel subfamily D member 2 JBrowse link 4 48,309,283 48,816,804 RGD:10047321
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 JBrowse link 1 102,103,093 102,107,134 RGD:1598637
RGD:1624291
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 JBrowse link 10 47,282,208 47,343,501 RGD:1581466
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 JBrowse link 10 99,429,337 99,442,520 RGD:7247427
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 JBrowse link 3 41,019,898 41,181,070 RGD:1581474
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 JBrowse link 8 33,435,493 33,463,410 RGD:1581474
G Kcnn2 potassium calcium-activated channel subfamily N member 2 JBrowse link 18 39,331,894 39,479,574 RGD:1624291
G Msn moesin JBrowse link X 65,226,834 65,294,192 RGD:7207798
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:1624291
RGD:1600115
G Nos1ap nitric oxide synthase 1 adaptor protein JBrowse link 13 88,653,123 88,943,976 RGD:1624291
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:1624291
RGD:1600115
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha JBrowse link 8 117,486,085 117,548,768 RGD:1304018
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:2317914
G Rdx radixin JBrowse link 8 56,570,728 56,612,851 RGD:7207798
G Rtn2 reticulon 2 JBrowse link 1 80,195,594 80,208,449 RGD:1624291
G Ryr1 ryanodine receptor 1 JBrowse link 1 87,959,596 88,066,252 RGD:1600115
RGD:1624291
G Scn1a sodium voltage-gated channel alpha subunit 1 JBrowse link 3 52,388,811 52,533,365 RGD:1624291
RGD:1600115
G Scn1b sodium voltage-gated channel beta subunit 1 JBrowse link 1 89,550,738 89,560,469 RGD:1624291
G Scn2a sodium voltage-gated channel alpha subunit 2 JBrowse link 3 51,687,910 51,822,008 RGD:1624291
RGD:1600115
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:6484228
RGD:1600115
RGD:1624291
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:7349316
G Slc30a1 solute carrier family 30 member 1 JBrowse link 13 110,677,810 110,681,683 RGD:8554228
G Slc8a1 solute carrier family 8 member A1 JBrowse link 6 4,244,076 4,564,262 RGD:2316982
RGD:1624291
RGD:8553384
RGD:8554533
G Slc9a1 solute carrier family 9 member A1 JBrowse link 5 151,573,122 151,626,360 RGD:7349316
G Sri sorcin JBrowse link 4 23,004,657 23,029,233 RGD:7327199
G Stac SH3 and cysteine rich domain JBrowse link 8 119,820,664 119,941,867 RGD:1624291
G Stbd1 starch binding domain 1 JBrowse link 14 16,976,355 16,979,760 RGD:1624291
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:1625705
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:4889912
L-type voltage-gated calcium channel complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1624291
RGD:1600115
RGD:11558004
G Cacna1d calcium voltage-gated channel subunit alpha1 D JBrowse link 16 6,110,294 6,405,022 RGD:1624291
RGD:1600115
G Cacna1s calcium voltage-gated channel subunit alpha1 S JBrowse link 13 52,889,570 52,964,558 RGD:1600115
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 JBrowse link 4 15,706,974 16,130,848 RGD:1624291
RGD:13792537
RGD:1600115
RGD:11059598
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 JBrowse link 17 81,673,862 82,019,219 RGD:1624291
RGD:12907551
RGD:1600115
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 JBrowse link 7 140,311,120 140,324,902 RGD:11059598
RGD:13673808
RGD:11558004
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 JBrowse link 10 95,921,479 95,934,170 RGD:1600115
RGD:13792537
RGD:69791
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 JBrowse link 10 95,954,160 96,015,484 RGD:1600115
RGD:1624291
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 JBrowse link 1 64,307,684 64,322,124 RGD:1600115
RGD:13792537
RGD:1624291
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 JBrowse link 1 64,374,547 64,405,380 RGD:1600115
RGD:1624291
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 JBrowse link 1 64,330,106 64,350,338 RGD:1600115
RGD:1624291
G Nos1ap nitric oxide synthase 1 adaptor protein JBrowse link 13 88,653,123 88,943,976 RGD:10047296

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19949
    cellular anatomical entity 19598
      T-tubule 72
        L-type voltage-gated calcium channel complex 12
Path 2
Term Annotations click to browse term
  cellular_component 19949
    cellular anatomical entity 19598
      membrane 9984
        plasma membrane 6135
          sarcolemma 174
            T-tubule 72
              L-type voltage-gated calcium channel complex 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.