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ONTOLOGY REPORT - ANNOTATIONS


Term:adrenal gland development
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Accession:GO:0030325 term browser browse the term
Definition:The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.
Synonyms:related_synonym: interrenal gland


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adrenal gland development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2a activin A receptor type 2A IEP RGD PMID:12844345 RGD:728125 NCBI chr 3:32,947,901...33,034,598
Ensembl chr 3:32,947,378...33,034,282
JBrowse link
G Acvr2b activin A receptor type 2B IEP RGD PMID:12844345 RGD:728125 NCBI chr 8:128,087,308...128,126,776
Ensembl chr 8:128,087,345...128,118,746
JBrowse link
G Apoa1 apolipoprotein A1 ISO MGI:MGI:2180783 (MGI:MGI:2180727|PMID:8647961) RGD PMID:8647961 MGI:MGI:2180727 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Arid5b AT-rich interaction domain 5B ISO MGI:MGI:2445941 (MGI:MGI:2137956|PMID:11483573) RGD PMID:11483573 MGI:MGI:2137956 NCBI chr20:21,713,900...21,881,193
Ensembl chr20:21,564,975...21,880,715
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C ISO MGI:MGI:1933758|MGI:MGI:3840687 (MGI:MGI:3839493|PMID:19276117) RGD PMID:19276117 MGI:MGI:3839493 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 ISO MGI:MGI:2179740 (MGI:MGI:2179743|PMID:11694877), (MGI:MGI:3606737|PMID:15615595) RGD PMID:11694877, PMID:15615595 MGI:MGI:2179743, MGI:MGI:3606737 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Crh corticotropin releasing hormone ISO MGI:MGI:1857392 (MGI:MGI:1860037|PMID:10861000) RGD PMID:10861000 MGI:MGI:1860037 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO (MGI:MGI:1267130|PMID:9655498) RGD PMID:9655498 MGI:MGI:1267130 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 IEP RGD PMID:7829497 RGD:1299585 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 IEP RGD PMID:17065412 RGD:4889133 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP RGD PMID:8097866 RGD:4145970 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IEP RGD PMID:10098502 RGD:7829725 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 ISO (PMID:12844346) RGD PMID:12844346 NCBI chr 1:176,940,424...176,983,076
Ensembl chr 1:176,940,693...176,983,045
JBrowse link
G Fdx1 ferredoxin 1 IEP RGD PMID:8097866 RGD:4145970 NCBI chr 8:56,373,729...56,393,199
Ensembl chr 8:56,373,723...56,393,233
JBrowse link
G Fstl3 follistatin like 3 IEP RGD PMID:14692692 RGD:1302294 NCBI chr 7:12,806,031...12,810,556
Ensembl chr 7:12,804,919...12,810,570
JBrowse link
G Hmga2 high mobility group AT-hook 2 ISO MGI:MGI:1858044 (MGI:MGI:69334|PMID:7958830) RGD PMID:7958830 MGI:MGI:69334 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP RGD PMID:1935797 RGD:4889583
G Igf1r insulin-like growth factor 1 receptor ISO UniProtKB:P15208 (MGI:MGI:5493430|PMID:23300479) RGD PMID:23300479 MGI:MGI:5493430 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Insr insulin receptor ISO
IEA
UniProtKB:Q60751 (MGI:MGI:5493430|PMID:23300479)
GO_REF:0000107
RGD
Ensembl
PMID:23300479 GO_REF:0000107, MGI:MGI:5493430 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Ly6e lymphocyte antigen 6 family member E ISO MGI:MGI:2429638 (MGI:MGI:2157257|PMID:11784869) RGD PMID:11784869 MGI:MGI:2157257 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Mdk midkine IDA PMID:11136554 UniProt PMID:11136554 RGD:62414 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Nf1 neurofibromin 1 ISO
ISS
IEA
MGI:MGI:1857444 (MGI:MGI:3689139|PMID:16906226)
GO_REF:0000024
GO_REF:0000107
RGD
HGNC
Ensembl
PMID:16906226 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3689139 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 ISO
IBA
ISS
IEA
(PMID:7990953)
PMID:21873635
GO_REF:0000024
GO_REF:0000107
MGI:MGI:1346833 (MGI:MGI:2159510|PMID:11796523)
RGD
HGNC
Ensembl
PMID:7990953, PMID:11796523, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:2159510, RGD:13792537 NCBI chr  X:54,734,385...54,738,513
Ensembl chr  X:54,734,385...54,738,513
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO MGI:MGI:1857745 (MGI:MGI:74913|PMID:7628695) RGD PMID:7628695 MGI:MGI:74913 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 ISO MGI:MGI:1352460|MGI:MGI:1857391|MGI:MGI:5292676 (MGI:MGI:2159510|PMID:11796523), (MGI:MGI:3604914|PMID:16176945), (MGI:MGI:5287526|PMID:21820362) RGD PMID:11796523, PMID:16176945, PMID:21820362 MGI:MGI:2159510, MGI:MGI:3604914, MGI:MGI:5287526 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Pbx1 PBX homeobox 1 ISO MGI:MGI:2155612 (MGI:MGI:2683990|PMID:14595835) RGD PMID:14595835 MGI:MGI:2683990 NCBI chr13:86,390,741...86,671,460
Ensembl chr13:86,390,741...86,451,002
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO
IEA
MGI:MGI:97531 (MGI:MGI:3820330|PMID:19056881)
GO_REF:0000107
RGD
Ensembl
PMID:19056881 GO_REF:0000107, MGI:MGI:3820330 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO MGI:MGI:97530 (MGI:MGI:3820330|PMID:19056881) RGD PMID:19056881 MGI:MGI:3820330 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IEP RGD PMID:16140489 RGD:5130728 NCBI chr10:86,340,893...86,342,501
Ensembl chr10:86,340,940...86,342,858
JBrowse link
G Sall1 spalt-like transcription factor 1 ISO (PMID:12065233) RGD PMID:12065233 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039
JBrowse link
G Smad2 SMAD family member 2 IDA RGD PMID:12844345 RGD:728125 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 IDA RGD PMID:12844345 RGD:728125 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smad4 SMAD family member 4 IEP RGD PMID:12844345 RGD:728125 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 ISO
IEA
(PMID:17273977)
GO_REF:0000107
RGD
Ensembl
PMID:17273977 GO_REF:0000107 NCBI chr 8:62,925,364...62,944,438
Ensembl chr 8:62,925,357...62,944,437
JBrowse link
G Thra thyroid hormone receptor alpha IEP RGD PMID:17496154 RGD:2314319 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Thra_v1 thyroid hormone receptor alpha, variant 1 IEP RGD PMID:17496154 RGD:2314319
G Thra_v2 thyroid hormone receptor alpha, variant 2 IEP RGD PMID:17496154 RGD:2314319
G Tspo translocator protein IEP RGD PMID:9927316 RGD:2317174 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
G Wnt11 Wnt family member 11 ISO (PMID:9757009) RGD PMID:9757009 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
G Wnt4 Wnt family member 4 IEA
ISO
GO_REF:0000107
(PMID:12844346)
Ensembl
RGD
PMID:12844346 GO_REF:0000107 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
G Wt1 WT1 transcription factor ISO
IEA
ISS
UniProtKB:P22561 (PMID:10101119)
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:1333093|PMID:10101119)
RGD
Ensembl
UniProt
PMID:10101119 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1333093 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
adrenal chromaffin cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO MGI:MGI:1857470 (MGI:MGI:2387977|PMID:12361965) RGD PMID:12361965 MGI:MGI:2387977 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510
JBrowse link
G Insm1 INSM transcriptional repressor 1 ISO (MGI:MGI:3772428|PMID:18094025) RGD PMID:18094025 MGI:MGI:3772428 NCBI chr 3:140,427,961...140,430,467 JBrowse link
adrenal cortex development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armc5 armadillo repeat containing 5 ISO
IEA
MGI:MGI:6157645 (MGI:MGI:5913685|PMID:28911199)
GO_REF:0000107
RGD
Ensembl
PMID:28911199 GO_REF:0000107, MGI:MGI:5913685 NCBI chr 1:199,655,069...199,662,419
Ensembl chr 1:199,655,660...199,662,427
JBrowse link
adrenal cortex formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 ISO (MGI:MGI:3790398|PMID:17537799) RGD PMID:17537799 MGI:MGI:3790398 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Wt1 WT1 transcription factor ISO
ISS
(MGI:MGI:3790398|PMID:17537799)
GO_REF:0000024
RGD
UniProt
PMID:17537799 GO_REF:0000024, MGI:MGI:3790398 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      anatomical structure development 6256
        animal organ development 4027
          gland development 664
            adrenal gland development 44
              adrenal chromaffin cell differentiation 2
              adrenal cortex development + 3
Path 2
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            animal organ development 4027
              gland development 664
                adrenal gland development 44
                  adrenal chromaffin cell differentiation 2
                  adrenal cortex development + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.