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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of complement activation
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Accession:GO:0030449 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of complement activation.
Synonyms:exact_synonym: regulation of complement cascade


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regulation of complement activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C1qbp complement C1q binding protein JBrowse link 10 57,613,876 57,618,527 RGD:1624291
RGD:13792537
RGD:1600115
G Cd55 CD55 molecule (Cromer blood group) JBrowse link 13 47,125,156 47,153,557 RGD:1624291
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:727654
RGD:13792537
RGD:1624291
G Cd5l Cd5 molecule-like JBrowse link 2 186,685,104 186,696,117 RGD:1624291
G Cfh complement factor H JBrowse link 13 56,979,155 57,080,540 RGD:628500
RGD:1624291
G Cr1l complement C3b/C4b receptor 1 like JBrowse link 13 113,824,886 113,872,097 RGD:1624291
G Phb2 prohibitin 2 JBrowse link 4 157,230,769 157,235,375 RGD:1624291
G Susd4 sushi domain containing 4 JBrowse link 13 101,181,932 101,307,912 RGD:1624291
negative regulation of activation of membrane attack complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:1600482
RGD:13792537
RGD:1624291
negative regulation of complement activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd55 CD55 molecule (Cromer blood group) JBrowse link 13 47,125,156 47,153,557 RGD:2326180
RGD:1624291
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:1624291
G Cr1l complement C3b/C4b receptor 1 like JBrowse link 13 113,824,886 113,872,097 RGD:625470
RGD:1624291
G Masp1 mannan-binding lectin serine peptidase 1 JBrowse link 11 80,736,424 80,806,278 RGD:1624291
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G Susd4 sushi domain containing 4 JBrowse link 13 101,181,932 101,307,912 RGD:1624291
RGD:13792537
G Vsig4 V-set and immunoglobulin domain containing 4 JBrowse link X 65,370,851 65,400,298 RGD:1624291
RGD:13792537
negative regulation of complement activation, classical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C4bpa complement component 4 binding protein, alpha JBrowse link 13 47,342,090 47,377,580 RGD:1624291
RGD:1600115
G C4bpb complement component 4 binding protein, beta JBrowse link 13 47,387,173 47,398,115 RGD:1624291
RGD:1600115
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G Susd4 sushi domain containing 4 JBrowse link 13 101,181,932 101,307,912 RGD:1624291
RGD:13792537
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2m alpha-2-macroglobulin JBrowse link 4 154,309,426 154,359,138 RGD:1624291
G Serping1 serpin family G member 1 JBrowse link 3 72,161,230 72,171,109 RGD:1624291
RGD:1600115
positive regulation of activation of membrane attack complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:1624291
RGD:1600115
G C6 complement C6 JBrowse link 2 54,460,333 54,533,801 RGD:1624291
positive regulation of complement activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C6 complement C6 JBrowse link 2 54,460,333 54,533,801 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:4889148
G Phb prohibitin JBrowse link 10 83,476,107 83,488,878 RGD:1624291
regulation of complement activation, classical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd55 CD55 molecule (Cromer blood group) JBrowse link 13 47,125,156 47,153,557 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19575
    immune system process 2692
      activation of immune response 393
        complement activation 151
          regulation of complement activation 20
            negative regulation of complement activation + 11
            positive regulation of complement activation + 5
            regulation of activation of membrane attack complex + 3
            regulation of complement activation, alternative pathway + 3
            regulation of complement activation, classical pathway + 5
            regulation of complement activation, lectin pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 19575
    biological regulation 13535
      regulation of biological process 12839
        regulation of response to stimulus 4027
          positive regulation of response to stimulus 2363
            positive regulation of immune response 647
              activation of immune response 393
                complement activation 151
                  regulation of complement activation 20
                    negative regulation of complement activation + 11
                    positive regulation of complement activation + 5
                    regulation of activation of membrane attack complex + 3
                    regulation of complement activation, alternative pathway + 3
                    regulation of complement activation, classical pathway + 5
                    regulation of complement activation, lectin pathway + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.