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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of bone mineralization
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Accession:GO:0030502 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization.
Synonyms:exact_synonym: down regulation of bone mineralization;   downregulation of bone mineralization
 narrow_synonym: inhibition of bone mineralization


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negative regulation of bone mineralization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahsg alpha-2-HS-glycoprotein IMP
ISS
ISO
GO_REF:0000024
(MGI:MGI:3687916|PMID:12556469)
UniProt
RGD
PMID:12556469, PMID:8702833 GO_REF:0000024, MGI:MGI:3687916, RGD:1626074 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Bcor BCL6 co-repressor ISO (PMID:19578371) RGD PMID:19578371 NCBI chr  X:11,570,155...11,692,022
Ensembl chr  X:11,648,989...11,691,099
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO (PMID:21403648) RGD PMID:21403648 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO (PMID:21403648) RGD PMID:21403648 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Ecm1 extracellular matrix protein 1 ISO
ISS
(PMID:11165938)
GO_REF:0000024
RGD
UniProt
PMID:11165938 GO_REF:0000024 NCBI chr 2:197,855,468...197,860,973
Ensembl chr 2:197,855,460...197,860,699
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISS
ISO
GO_REF:0000024
(MGI:MGI:5607146|PMID:25479107), (MGI:MGI:6220772|PMID:30111653), (MGI:MGI:6294341|PMID:22510396)
UniProt
RGD
PMID:22510396, PMID:25479107, PMID:30111653 GO_REF:0000024, MGI:MGI:5607146, MGI:MGI:6220772, MGI:MGI:6294341 NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371
JBrowse link
G Fgf23 fibroblast growth factor 23 ISO (PMID:18282132) RGD PMID:18282132 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link
G Gata1 GATA binding protein 1 ISO MGI:MGI:2177586 (MGI:MGI:3653541|PMID:15005853) RGD PMID:15005853 MGI:MGI:3653541 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO
IEA
MGI:MGI:1857719 (MGI:MGI:3777866|PMID:17181398)
GO_REF:0000107
RGD
Ensembl
PMID:17181398 GO_REF:0000107, MGI:MGI:3777866 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 ISO MGI:MGI:2180017 (MGI:MGI:2178869|PMID:11790802) RGD PMID:11790802 MGI:MGI:2178869 NCBI chr 1:221,099,155...221,116,096
Ensembl chr 1:221,099,998...221,116,096
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein ISO MGI:MGI:2448895 (MGI:MGI:2448336|PMID:12421822), (MGI:MGI:3851320|PMID:15843468), (MGI:MGI:5431257|PMID:22766095) RGD PMID:12421822, PMID:15843468, PMID:22766095 MGI:MGI:2448336, MGI:MGI:3851320, MGI:MGI:5431257 NCBI chr14:6,782,011...6,793,561
Ensembl chr14:6,782,012...6,793,558
JBrowse link
G Nfe2 nuclear factor, erythroid 2 ISO MGI:MGI:1857224 (MGI:MGI:3653541|PMID:15005853) RGD PMID:15005853 MGI:MGI:3653541 NCBI chr 7:144,872,739...144,880,092
Ensembl chr 7:144,872,747...144,880,092
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta ISO
ISS
(MGI:MGI:3713957|PMID:17537919)
GO_REF:0000024
RGD
UniProt
PMID:17537919 GO_REF:0000024, MGI:MGI:3713957 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Sox9 SRY-box transcription factor 9 ISO MGI:MGI:2158693 (MGI:MGI:2135696|PMID:11371614) RGD PMID:11371614 MGI:MGI:2135696 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Srgn serglycin ISO
IBA
ISS
(PMID:16870619)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:16870619, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr20:32,120,317...32,158,071
Ensembl chr20:32,120,320...32,139,789
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:23081848 RGD:10003033 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Pth parathyroid hormone IMP PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Rflna refilin A ISO
IBA
MGI:MGI:1923816 (MGI:MGI:5570967|PMID:24436304)
PMID:21873635
RGD PMID:24436304, PMID:21873635 MGI:MGI:5570967, RGD:13792537 NCBI chr12:37,038,732...37,047,628
Ensembl chr12:37,038,733...37,047,628
JBrowse link
G Rflnb refilin B ISO
IBA
MGI:MGI:1920371 (MGI:MGI:5570967|PMID:24436304)
PMID:21873635
RGD PMID:24436304, PMID:21873635 MGI:MGI:5570967, RGD:13792537 NCBI chr10:64,196,103...64,202,380
Ensembl chr10:64,196,127...64,202,380
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    multicellular organismal process 9046
      ossification 432
        negative regulation of ossification 42
          negative regulation of bone mineralization 20
            negative regulation of bone mineralization involved in bone maturation 4
Path 2
Term Annotations click to browse term
  biological_process 20028
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            animal organ development 4035
              biomineral tissue development 171
                regulation of biomineral tissue development 100
                  regulation of bone mineralization 83
                    negative regulation of bone mineralization 20
                      negative regulation of bone mineralization involved in bone maturation 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.