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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of axon extension
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Accession:GO:0030517 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.
Synonyms:exact_synonym: down regulation of axon extension;   downregulation of axon extension
 narrow_synonym: inhibition of axon extension


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negative regulation of axon extension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatk apoptosis-associated tyrosine kinase ISO MGI:MGI:101764|MGI:MGI:5428170 (MGI:MGI:5426470|PMID:22573681) RGD PMID:22573681 MGI:MGI:5426470 NCBI chr10:109,184,338...109,224,455
Ensembl chr10:109,188,112...109,224,370
JBrowse link
G Actr3 actin related protein 3 IMP RGD PMID:19846719 RGD:11530054 NCBI chr13:41,695,520...41,738,622
Ensembl chr13:41,695,183...41,738,658
JBrowse link
G Arhgap4 Rho GTPase activating protein 4 IMP RGD PMID:17804252 RGD:2313143 NCBI chr  X:156,873,094...156,888,762
Ensembl chr  X:156,873,849...156,888,761
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IMP RGD PMID:16537566 RGD:4890441 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cdk5 cyclin-dependent kinase 5 ISO MGI:MGI:1197518 (MGI:MGI:5426470|PMID:22573681) RGD PMID:22573681 MGI:MGI:5426470 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 ISO MGI:MGI:1197518 (MGI:MGI:5426470|PMID:22573681) RGD PMID:22573681 MGI:MGI:5426470 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Cdkl3 cyclin-dependent kinase-like 3 IMP
IBA
ISO
PMID:20347982
PMID:21873635
(MGI:MGI:4835107|PMID:20347982)
RGD PMID:20347982, PMID:20347982, PMID:21873635 MGI:MGI:4835107, RGD:8693354, RGD:13792537 NCBI chr10:37,458,397...37,510,345
Ensembl chr10:37,458,452...37,493,491
JBrowse link
G Draxin dorsal inhibitory axon guidance protein ISO (MGI:MGI:4830206|PMID:20621059) RGD PMID:20621059 MGI:MGI:4830206 NCBI chr 5:164,913,085...164,943,012
Ensembl chr 5:164,913,906...164,927,869
JBrowse link
G Fstl4 follistatin-like 4 NOT ISO (MGI:MGI:5566541|PMID:24573299) RGD PMID:24573299 MGI:MGI:5566541 NCBI chr10:38,104,344...38,532,216
Ensembl chr10:38,104,558...38,532,196
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 ISO
IEA
MGI:MGI:97321 (MGI:MGI:3771687|PMID:18052984)
GO_REF:0000107
RGD
Ensembl
PMID:18052984 GO_REF:0000107, MGI:MGI:3771687 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Mag myelin-associated glycoprotein IMP PMID:9298990 UniProt PMID:9298990 RGD:12050149 NCBI chr 1:89,345,325...89,360,905
Ensembl chr 1:89,345,429...89,360,733
JBrowse link
G Map2 microtubule-associated protein 2 IMP
ISO
IEA
PMID:28426968
(MGI:MGI:6148385|PMID:28426968)
GO_REF:0000107
RGD
Ensembl
PMID:28426968, PMID:28426968 GO_REF:0000107, MGI:MGI:6148385, RGD:13514087 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mt3 metallothionein 3 ISS
ISO
GO_REF:0000024
(PMID:16601975), (PMID:17712581)
UniProt
RGD
PMID:16601975, PMID:17712581 GO_REF:0000024 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Nrp1 neuropilin 1 ISO MGI:MGI:107558 (MGI:MGI:3505728|PMID:12852851) RGD PMID:12852851 MGI:MGI:3505728 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Ntn1 netrin 1 ISO
IEA
(MGI:MGI:1353949|PMID:10704383)
GO_REF:0000107
RGD
Ensembl
PMID:10704383 GO_REF:0000107, MGI:MGI:1353949 NCBI chr10:54,761,925...54,982,072
Ensembl chr10:54,761,871...54,967,585
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:4880863|PMID:19780196)
Ensembl
UniProt
RGD
PMID:19780196 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4880863 NCBI chr 9:10,585,360...10,646,205
Ensembl chr 9:10,603,813...10,645,939
JBrowse link
G RGD1307443 similar to mKIAA0319 protein ISO (PMID:28334068) RGD PMID:28334068 NCBI chr17:42,163,245...42,226,725
Ensembl chr17:42,165,817...42,226,377
JBrowse link
G Rnf6 ring finger protein 6 ISO MGI:MGI:104572 (MGI:MGI:3603857|PMID:16204183) RGD PMID:16204183 MGI:MGI:3603857 NCBI chr12:10,574,168...10,583,196
Ensembl chr12:10,574,168...10,583,208
JBrowse link
G Rtn4 reticulon 4 IDA
ISS
ISO
IEA
PMID:20573699
PMID:10667797
(MGI:MGI:4830045|PMID:20573699)
(PMID:10667797)
GO_REF:0000107
RGD
Ensembl
PMID:10667797, PMID:20573699, PMID:20573699, PMID:10667797 GO_REF:0000107, MGI:MGI:4830045, RGD:8554113, RGD:8553459 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458
JBrowse link
G Rtn4r reticulon 4 receptor ISO
ISS
(MGI:MGI:5688832|PMID:22923615)
GO_REF:0000024
RGD
UniProt
PMID:22923615 GO_REF:0000024, MGI:MGI:5688832 NCBI chr11:86,992,665...87,017,091
Ensembl chr11:86,992,399...87,017,115
JBrowse link
G Sema3a semaphorin 3A IDA
ISO
MGI:MGI:106206 (MGI:MGI:3505728|PMID:12852851) RGD PMID:12852851, PMID:12077190 MGI:MGI:3505728, RGD:628318 NCBI chr 4:18,170,375...18,545,190
Ensembl chr 4:18,178,656...18,396,035
JBrowse link
G Sema3g semaphorin 3G ISO (MGI:MGI:3619679|PMID:16098142) RGD PMID:16098142 MGI:MGI:3619679 NCBI chr16:7,303,582...7,315,214
Ensembl chr16:7,303,578...7,315,390
JBrowse link
G Sema4f ssemaphorin 4F IDA PMID:10051670 MGI PMID:10051670 RGD:69991 NCBI chr 4:113,738,225...113,764,532
Ensembl chr 4:113,738,226...113,764,532
JBrowse link
G Sema6c semaphorin 6C ISO (PMID:12110693) RGD PMID:12110693 NCBI chr 2:196,330,777...196,347,218
Ensembl chr 2:196,334,626...196,344,008
JBrowse link
G Sema6d semaphorin 6D ISO (PMID:12110693) RGD PMID:12110693 NCBI chr 3:116,899,906...116,958,059
Ensembl chr 3:116,899,878...116,958,050
JBrowse link
G Slit2 slit guidance ligand 2 ISO (MGI:MGI:2683853|PMID:12879062) RGD PMID:12879062 MGI:MGI:2683853 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
G Tnr tenascin R ISO (MGI:MGI:3655167|PMID:16831557) RGD PMID:16831557 MGI:MGI:3655167 NCBI chr13:77,602,249...77,678,385
Ensembl chr13:77,485,113...77,678,437
JBrowse link
G Trim46 tripartite motif-containing 46 IMP PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr 2:188,548,608...188,561,617
Ensembl chr 2:188,548,644...188,561,360
JBrowse link
negative regulation of axon extension involved in axon guidance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 IMP RGD PMID:19884510 RGD:9681717 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Nrp1 neuropilin 1 IMP
ISO
(MGI:MGI:1289520|PMID:9753685) RGD PMID:9753685, PMID:9288754 MGI:MGI:1289520, RGD:633436 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Plxna3 plexin A3 ISO MGI:MGI:107558|MGI:MGI:1096347 (MGI:MGI:2152659|PMID:11683995) RGD PMID:11683995 MGI:MGI:2152659 NCBI chr  X:156,363,400...156,379,433
Ensembl chr  X:156,363,405...156,379,189
JBrowse link
G Ryk receptor-like tyrosine kinase ISO MGI:MGI:98958 (MGI:MGI:3625635|PMID:16723543) RGD PMID:16723543 MGI:MGI:3625635 NCBI chr 8:111,326,339...111,398,640
Ensembl chr 8:111,326,433...111,397,867
JBrowse link
G Sema3a semaphorin 3A ISO
IBA
MGI:MGI:104518|MGI:MGI:107683|MGI:MGI:96721 (MGI:MGI:1289520|PMID:9753685), (MGI:MGI:2152659|PMID:11683995), (MGI:MGI:3801368|PMID:18550718), (MGI:MGI:73216|PMID:7748561)
PMID:21873635
RGD PMID:7748561, PMID:9753685, PMID:11683995, PMID:18550718, PMID:21873635 MGI:MGI:1289520, MGI:MGI:2152659, MGI:MGI:3801368, MGI:MGI:73216, RGD:13792537 NCBI chr 4:18,170,375...18,545,190
Ensembl chr 4:18,178,656...18,396,035
JBrowse link
G Sema3b semaphorin 3B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:116,353,791...116,362,655
Ensembl chr 8:116,354,073...116,361,343
JBrowse link
G Sema3c semaphorin 3C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:14,318,276...14,490,438
Ensembl chr 4:14,318,274...14,490,446
JBrowse link
G Sema3d semaphorin 3D IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:19,224,378...19,413,519
Ensembl chr 4:19,224,310...19,413,484
JBrowse link
G Sema3e semaphorin 3E IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:17,314,745...17,594,659
Ensembl chr 4:17,272,511...17,594,598
JBrowse link
G Sema3f semaphorin 3F ISO
IBA
MGI:MGI:107683 (MGI:MGI:1289520|PMID:9753685), (MGI:MGI:2152659|PMID:11683995)
PMID:21873635
RGD PMID:9753685, PMID:11683995, PMID:21873635 MGI:MGI:1289520, MGI:MGI:2152659, RGD:13792537 NCBI chr 8:116,439,996...116,469,915
Ensembl chr 8:116,437,696...116,469,915
JBrowse link
G Sema3g semaphorin 3G IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:7,303,582...7,315,214
Ensembl chr16:7,303,578...7,315,390
JBrowse link
G Sema4a semaphorin 4A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:187,799,568...187,823,014
Ensembl chr 2:187,799,568...187,822,997
JBrowse link
G Sema4b semaphorin 4B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:141,986,145...142,014,400
Ensembl chr 1:141,986,145...142,014,398
JBrowse link
G Sema4c semaphorin 4C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:43,129,413...43,140,442
Ensembl chr 9:43,129,415...43,139,870
JBrowse link
G Sema4d semaphorin 4D IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:13,516,276...13,538,513
Ensembl chr17:13,488,376...13,553,974
JBrowse link
G Sema4f ssemaphorin 4F IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:113,738,225...113,764,532
Ensembl chr 4:113,738,226...113,764,532
JBrowse link
G Sema4g semaphorin 4G IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:264,738,935...264,753,399
Ensembl chr 1:264,741,911...264,753,397
JBrowse link
G Sema5a semaphorin 5A IMP
IBA
PMID:15603739
PMID:21873635
UniProt
GO_Central
PMID:15603739, PMID:21873635 RGD:8553809, RGD:13792537 NCBI chr 2:85,377,318...85,808,970
Ensembl chr 2:85,377,318...85,808,970
JBrowse link
G Sema5b semaphorin 5B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:68,304,844...68,435,109
Ensembl chr11:68,306,659...68,349,238
JBrowse link
G Sema6a semaphorin 6A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:41,330,519...41,451,813
Ensembl chr18:41,333,551...41,389,510
JBrowse link
G Sema6b semaphorin 6B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:10,934,273...10,951,252
Ensembl chr 9:10,941,613...10,951,252
JBrowse link
G Sema6c semaphorin 6C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:196,330,777...196,347,218
Ensembl chr 2:196,334,626...196,344,008
JBrowse link
G Sema6d semaphorin 6D IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:116,899,906...116,958,059
Ensembl chr 3:116,899,878...116,958,050
JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:62,723,788...62,746,530
Ensembl chr 8:62,723,788...62,745,868
JBrowse link
G Slit1 slit guidance ligand 1 IDA RGD PMID:15632296 RGD:1358459 NCBI chr 1:260,843,481...260,992,366
Ensembl chr 1:260,843,483...260,992,366
JBrowse link
G Wnt3 Wnt family member 3 ISO (MGI:MGI:3806438|PMID:18716223) RGD PMID:18716223 MGI:MGI:3806438 NCBI chr10:91,830,709...91,874,907
Ensembl chr10:91,830,654...91,874,793
JBrowse link
G Wnt3a Wnt family member 3A ISO (MGI:MGI:3806438|PMID:18716223) RGD PMID:18716223 MGI:MGI:3806438 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Wnt5a Wnt family member 5A ISO
IEA
MGI:MGI:101766 (MGI:MGI:3625635|PMID:16723543)
GO_REF:0000107
RGD
Ensembl
PMID:16723543 GO_REF:0000107, MGI:MGI:3625635 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
negative regulation of axon extension involved in regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGD1307443 similar to mKIAA0319 protein ISO MGI:MGI:4362922 (MGI:MGI:5904726|PMID:28334068)
(PMID:28334068)
RGD PMID:28334068 MGI:MGI:5904726 NCBI chr17:42,163,245...42,226,725
Ensembl chr17:42,165,817...42,226,377
JBrowse link
G Tnr tenascin R ISO
IEA
MGI:MGI:2154583 (MGI:MGI:3652670|PMID:16870730)
GO_REF:0000107
RGD
Ensembl
PMID:16870730 GO_REF:0000107, MGI:MGI:3652670 NCBI chr13:77,602,249...77,678,385
Ensembl chr13:77,485,113...77,678,437
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    cellular process 18788
      cell growth 530
        negative regulation of cell growth 205
          negative regulation of axon extension 50
            negative regulation of axon extension involved in axon guidance 28
            negative regulation of axon extension involved in regeneration 2
Path 2
Term Annotations click to browse term
  biological_process 20015
    developmental process 6813
      anatomical structure development 6257
        multicellular organism development 5736
          system development 5273
            nervous system development 2717
              neurogenesis 1936
                generation of neurons 1793
                  neuron differentiation 1615
                    neuron development 1321
                      neuron projection development 1161
                        neuron projection morphogenesis 720
                          axonogenesis 494
                            axon extension 144
                              regulation of axon extension 118
                                negative regulation of axon extension 50
                                  negative regulation of axon extension involved in axon guidance 28
                                  negative regulation of axon extension involved in regeneration 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.