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ONTOLOGY REPORT - ANNOTATIONS


Term:collagen catabolic process
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Accession:GO:0030574 term browser browse the term
Definition:The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.
Synonyms:exact_synonym: collagen breakdown;   collagen catabolism;   collagen degradation


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collagen catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07069011.1 RGD:13792537
G Adam15 ADAM metallopeptidase domain 15 JBrowse link 2 188,661,831 188,672,337 RGD:1600115
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:1624291
RGD:1600115
G Ctsk cathepsin K JBrowse link 2 196,655,469 196,666,447 RGD:1624291
G Ctsl cathepsin L JBrowse link 17 1,873,105 1,879,266 RGD:1624291
RGD:1600115
G Ctss cathepsin S JBrowse link 2 197,655,780 197,679,768 RGD:1624291
RGD:1600115
G LOC103694864 matrix metalloproteinase-28-like RGD:13792537
G LOC103694874 stromelysin-3 RGD:13792537
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:1600115
G Mmp10 matrix metallopeptidase 10 JBrowse link 8 5,734,348 5,742,243 RGD:13792537
G Mmp11 matrix metallopeptidase 11 JBrowse link 20 13,670,051 13,678,834 RGD:1624291
RGD:13792537
G Mmp12 matrix metallopeptidase 12 JBrowse link 8 5,594,717 5,616,494 RGD:13792537
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:1600115
RGD:13792537
RGD:1624291
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:1624291
RGD:13792537
G Mmp15 matrix metallopeptidase 15 JBrowse link 19 10,079,881 10,101,380 RGD:13792537
G Mmp16 matrix metallopeptidase 16 JBrowse link 5 31,568,344 31,818,368 RGD:1624291
RGD:13792537
RGD:1600115
G Mmp17 matrix metallopeptidase 17 JBrowse link 12
12
30,353,874
30,701,900
30,356,526
30,728,683
RGD:13792537
G Mmp19 matrix metallopeptidase 19 JBrowse link 7 3,216,392 3,224,202 RGD:13792537
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) JBrowse link 8 5,622,657 5,688,762 RGD:13792537
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:1624291
RGD:13792537
RGD:1600115
RGD:7207278
G Mmp20 matrix metallopeptidase 20 JBrowse link 8 5,823,147 5,875,555 RGD:13792537
G Mmp21 matrix metallopeptidase 21 JBrowse link 1 205,745,119 205,750,786 RGD:13792537
G Mmp23 matrix metallopeptidase 23 JBrowse link 5 173,078,811 173,082,834 RGD:13792537
G Mmp24 matrix metallopeptidase 24 JBrowse link 3 151,307,309 151,355,401 RGD:13792537
G Mmp27 matrix metallopeptidase 27 JBrowse link 8 5,790,019 5,799,938 RGD:13792537
G Mmp28 matrix metallopeptidase 28 JBrowse link 10 70,660,691 70,681,672 RGD:13792537
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:13792537
G Mmp7 matrix metallopeptidase 7 JBrowse link 8 5,893,253 5,900,965 RGD:13792537
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:13792537
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:7207278
RGD:13792537
RGD:1600115
RGD:1624291
G Mrc2 mannose receptor, C type 2 JBrowse link 10 93,520,272 93,581,599 RGD:1600115
RGD:1624291
G Pepd peptidase D JBrowse link 1 90,820,670 91,285,128 RGD:1600115
G Prss2 protease, serine, 2 JBrowse link 4 70,689,737 70,694,816 RGD:1600115
negative regulation of collagen catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cst3 cystatin C JBrowse link 3 143,219,671 143,223,544 RGD:1624291
positive regulation of collagen catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Idua alpha-L-iduronidase JBrowse link 14 2,041,828 2,056,762 RGD:1624291
G Vsir V-set immunoregulatory receptor JBrowse link 20 29,897,543 29,923,381 RGD:1624291
regulation of collagen catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fap fibroblast activation protein, alpha JBrowse link 3 48,467,781 48,536,242 RGD:1624291
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:1600115
RGD:1624291

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  biological_process 19676
    metabolic process 11952
      collagen metabolic process 113
        collagen catabolic process 38
          negative regulation of collagen catabolic process 1
          positive regulation of collagen catabolic process 2
          regulation of collagen catabolic process + 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.