ONTOLOGY REPORT - ANNOTATIONS


Term:prostate gland development
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Accession:GO:0030850 term browser browse the term
Definition:The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.
Synonyms:exact_synonym: prostate development
 xref: MIPS_funcat:47.03.15.09


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prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:1624291
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:7421658
RGD:13792537
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:8694133
G Fkbp4 FKBP prolyl isomerase 4 JBrowse link 4 161,748,993 161,757,447 RGD:1624291
RGD:1600115
G Gli1 GLI family zinc finger 1 JBrowse link 7 70,620,794 70,633,171 RGD:1303367
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1303367
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1303367
G Hoxa10 homeobox A10 JBrowse link 4 82,285,940 82,295,892 RGD:11354895
G Hoxa11 homeobox A11 JBrowse link 4 82,296,888 82,301,419 RGD:11354895
G Hoxa13 homeo box A13 RGD:11354895
G Hoxa9 homeobox A9 RGD:11354895
G Hoxb13 homeo box B13 JBrowse link 10 84,031,955 84,034,228 RGD:11354895
G Hoxd13 homeo box D13 JBrowse link 3 61,590,376 61,593,692 RGD:11354895
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1624291
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1303367
G Rara retinoic acid receptor, alpha JBrowse link 10 86,838,819 86,884,224 RGD:625676
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1303367
RGD:1624291
RGD:1600115
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 JBrowse link 8 118,206,678 118,326,264 RGD:9586354
G Sox9 SRY box 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:2317894
activation of prostate induction by androgen receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
branching involved in prostate gland morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:1624291
G Fem1b fem-1 homolog B JBrowse link 8 67,695,041 67,708,313 RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Hoxa13 homeo box A13 RGD:1624291
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1600115
RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
epithelial cell differentiation involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Plaur plasminogen activator, urokinase receptor JBrowse link 1 81,328,171 81,344,954 RGD:729659
G Psap prosaposin JBrowse link 20 29,831,302 29,856,876 RGD:1624291
RGD:13792537
RGD:1600115
G Psapl1 prosaposin-like 1 JBrowse link 14 79,711,694 79,714,254 RGD:13792537
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:1624291
epithelial cell maturation involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:1624291
G Fem1b fem-1 homolog B JBrowse link 8 67,695,041 67,708,313 RGD:1624291
RGD:1600115
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
RGD:1600115
G Hoxb13 homeo box B13 JBrowse link 10 84,031,955 84,034,228 RGD:1624291
RGD:1600115
epithelial cell proliferation involved in prostatic bud elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sox9 SRY box 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
epithelial-mesenchymal signaling involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
mesenchymal smoothened signaling pathway involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
mesenchymal-epithelial cell signaling involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:1624291
RGD:1600115
negative regulation of epithelial cell proliferation involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:1624291
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:1624291
RGD:1600115
G Eaf2 ELL associated factor 2 JBrowse link 11 66,878,658 66,923,092 RGD:1624291
RGD:1600115
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1600115
RGD:1624291
G Serpinf1 serpin family F member 1 JBrowse link 10 62,241,750 62,254,145 RGD:1624291
RGD:1600115
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:1624291
RGD:1600115
G Wdr77 WD repeat domain 77 JBrowse link 2 208,577,292 208,587,263 RGD:1624291
negative regulation of prostatic bud formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
RGD:1600115
G Sulf1 sulfatase 1 JBrowse link 5 5,999,520 6,186,901 RGD:1600115
RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
positive regulation of epithelial cell proliferation involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
primary prostatic bud elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Frs2 fibroblast growth factor receptor substrate 2 JBrowse link 7 60,128,506 60,210,482 RGD:1624291
RGD:1600115
G Hoxb13 homeo box B13 JBrowse link 10 84,031,955 84,034,228 RGD:1624291
RGD:1600115
G Hoxd13 homeo box D13 JBrowse link 3 61,590,376 61,593,692 RGD:1624291
RGD:1600115
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1624291
RGD:1600115
prostate epithelial cord elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
prostate gland epithelium morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 JBrowse link 2 102,701,903 102,871,257 RGD:1624291
RGD:1600115
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:1624291
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
RGD:1600115
G Id4 inhibitor of DNA binding 4, HLH protein JBrowse link 17 16,692,557 16,695,126 RGD:1624291
RGD:1600115
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:1624291
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:2325693
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Rarg retinoic acid receptor, gamma JBrowse link 7 143,840,739 143,863,206 RGD:1624291
RGD:1600115
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:1624291
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:1624291
RGD:1600115
prostate gland growth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:10043328
RGD:1624291
RGD:1600115
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:1600115
RGD:1624291
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Plag1 PLAG1 zinc finger JBrowse link 5 16,788,186 16,842,827 RGD:1624291
RGD:1600115
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:1624291
RGD:1600115
G Psap prosaposin JBrowse link 20 29,831,302 29,856,876 RGD:1624291
RGD:13792537
RGD:1600115
G Psapl1 prosaposin-like 1 JBrowse link 14 79,711,694 79,714,254 RGD:13792537
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115
G Rln1 relaxin 1 JBrowse link 1 247,483,298 247,486,331 RGD:1624291
G Ube3a ubiquitin protein ligase E3A JBrowse link 1 116,586,901 116,678,161 RGD:1624291
RGD:1600115
prostate gland morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Id4 inhibitor of DNA binding 4, HLH protein JBrowse link 17 16,692,557 16,695,126 RGD:1624291
G Serpinb5 serpin family B member 5 JBrowse link 13 26,903,052 26,923,250 RGD:1624291
RGD:1600115
G Sox9 SRY box 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
prostate gland stromal morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crip1 cysteine rich protein 1 JBrowse link 6 137,959,171 137,967,042 RGD:1624291
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
RGD:1600115
G Id4 inhibitor of DNA binding 4, HLH protein JBrowse link 17 16,692,557 16,695,126 RGD:1624291
RGD:1600115
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
prostatic bud formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:1624291
RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:1624291
RGD:1600115
regulation of branching involved in prostate gland morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
RGD:1600115
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1600115
RGD:1624291
G Hoxd13 homeo box D13 JBrowse link 3 61,590,376 61,593,692 RGD:1624291
RGD:1600115
G Rxra retinoid X receptor alpha JBrowse link 3 6,272,560 6,295,354 RGD:1624291
RGD:1600115
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1624291
RGD:1600115
regulation of epithelial cell proliferation involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
regulation of mesenchymal cell proliferation involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
regulation of prostatic bud formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1600115
RGD:1624291
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxa1 forkhead box A1 JBrowse link 6 78,516,579 78,549,669 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Rxra retinoid X receptor alpha JBrowse link 3 6,272,560 6,295,354 RGD:1624291
RGD:1600115
G Wdr77 WD repeat domain 77 JBrowse link 2 208,577,292 208,587,263 RGD:1624291
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:1624291
RGD:1600115
stromal-epithelial cell signaling involved in prostate gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    developmental process 6339
      anatomical structure development 5946
        reproductive structure development 566
          prostate gland development 62
            epithelial cell differentiation involved in prostate gland development + 15
            epithelial cell proliferation involved in prostate gland development + 12
            epithelial-mesenchymal signaling involved in prostate gland development + 2
            mesenchymal cell proliferation involved in prostate gland development + 1
            mesenchymal-epithelial cell signaling involved in prostate gland development + 1
            prostate gland growth + 14
            prostate gland morphogenesis + 35
            prostate glandular acinus development + 12
            stromal-epithelial cell signaling involved in prostate gland development 1
Path 2
Term Annotations click to browse term
  biological_process 17926
    developmental process 6339
      anatomical structure development 5946
        multicellular organism development 5440
          system development 5021
            reproductive system development 571
              reproductive structure development 566
                prostate gland development 62
                  epithelial cell differentiation involved in prostate gland development + 15
                  epithelial cell proliferation involved in prostate gland development + 12
                  epithelial-mesenchymal signaling involved in prostate gland development + 2
                  mesenchymal cell proliferation involved in prostate gland development + 1
                  mesenchymal-epithelial cell signaling involved in prostate gland development + 1
                  prostate gland growth + 14
                  prostate gland morphogenesis + 35
                  prostate glandular acinus development + 12
                  stromal-epithelial cell signaling involved in prostate gland development 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.