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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of epithelial cell differentiation
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Accession:GO:0030857 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation.
Synonyms:exact_synonym: down regulation of epithelial cell differentiation;   downregulation of epithelial cell differentiation
 narrow_synonym: inhibition of epithelial cell differentiation


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negative regulation of epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1624291
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1624291
RGD:1600115
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:8554478
G Nkx6-3 NK6 homeobox 3 JBrowse link 16 73,665,269 73,670,482 RGD:1624291
G Osr1 odd-skipped related transcription factor 1 JBrowse link 6 35,314,431 35,321,458 RGD:1624291
RGD:1600115
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:1600115
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
G Tbx3 T-box transcription factor 3 JBrowse link 12 42,479,518 42,494,588 RGD:1624291
G Yap1 Yes1 associated transcriptional regulator JBrowse link 8 6,133,014 6,204,240 RGD:1624291
G Zeb1 zinc finger E-box binding homeobox 1 JBrowse link 17 54,656,627 54,714,920 RGD:1624291
inhibition of neuroepithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
negative regulation of blood vessel endothelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxj2 forkhead box J2 JBrowse link 4 155,653,446 155,679,815 RGD:1624291
negative regulation of cornification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdsn corneodesmosin JBrowse link 20 3,704,626 3,707,266 RGD:1624291
negative regulation of endothelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvrl1 activin A receptor like type 1 JBrowse link 7 142,769,942 142,787,336 RGD:1624291
G Id1 inhibitor of DNA binding 1, HLH protein JBrowse link 3 148,214,623 148,216,715 RGD:9686141
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:1600115
RGD:1624291
G Notch4 notch receptor 4 JBrowse link 20 4,329,794 4,353,868 RGD:1624291
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:2302022
G Vhl von Hippel-Lindau tumor suppressor JBrowse link 4 145,580,869 145,587,835 RGD:1624291
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:1600115
RGD:1624291
G Zeb1 zinc finger E-box binding homeobox 1 JBrowse link 17 54,656,627 54,714,920 RGD:1624291
RGD:1600115
negative regulation of epidermal cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1624291
RGD:1600115
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:1624291
G Gdf3 growth differentiation factor 3 JBrowse link 4 155,417,667 155,422,014 RGD:1624291
negative regulation of epithelial cell differentiation involved in kidney development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:1600115
RGD:1624291
negative regulation of establishment of endothelial barrier term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G S1pr3 sphingosine-1-phosphate receptor 3 JBrowse link 17 13,799,383 13,812,877 RGD:1624291
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
negative regulation of establishment of Sertoli cell barrier term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:10046056
negative regulation of hepatocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Frzb frizzled-related protein JBrowse link 3 67,635,604 67,668,772 RGD:1624291
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1624291
RGD:1600115
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1600115
RGD:1624291
G Hes5 hes family bHLH transcription factor 5 JBrowse link 5 172,364,421 172,365,188 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
negative regulation of keratinocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grhl2 grainyhead-like transcription factor 2 JBrowse link 7 76,058,623 76,197,360 RGD:1624291
G Hoxa7 homeobox A7 JBrowse link 4 82,184,299 82,187,890 RGD:1624291
G Msx2 msh homeobox 2 JBrowse link 17 11,683,862 11,689,527 RGD:1624291
RGD:1600115
G Ovol2 ovo-like zinc finger 2 JBrowse link 3 138,433,990 138,464,511 RGD:1624291
G Reg3a regenerating islet-derived 3 alpha JBrowse link 4 109,477,893 109,480,659 RGD:1600115
RGD:1624291
G Reg3g regenerating family member 3 gamma JBrowse link 4 109,529,679 109,532,234 RGD:1624291
RGD:1600115
G Srsf6 serine and arginine rich splicing factor 6 JBrowse link 3 159,305,345 159,310,668 RGD:1624291
RGD:1600115
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:1624291
negative regulation of lens fiber cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxe3 forkhead box E3 JBrowse link 5 133,724,796 133,725,656 RGD:10047273
RGD:1624291
negative regulation of lung goblet cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
G Foxp4 forkhead box P4 JBrowse link 9 15,068,378 15,124,962 RGD:1624291
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 JBrowse link X 72,128,996 72,133,692 RGD:8554075
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
negative regulation of nephron tubule epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Osr1 odd-skipped related transcription factor 1 JBrowse link 6 35,314,431 35,321,458 RGD:1624291
RGD:1600115
negative regulation of pancreatic A cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Mir7a1 microRNA 7a-1 JBrowse link 17 6,675,016 6,675,112 RGD:1624291
negative regulation of stomach neuroendocrine cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
negative regulation of type B pancreatic cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:11567224

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    cellular process 18179
      negative regulation of cellular process 5051
        negative regulation of cell differentiation 813
          negative regulation of epithelial cell differentiation 47
            inhibition of neuroepithelial cell differentiation + 5
            negative regulation of border follicle cell delamination 0
            negative regulation of border follicle cell migration 0
            negative regulation of cumulus cell differentiation 0
            negative regulation of endothelial cell differentiation + 11
            negative regulation of epidermal cell differentiation + 15
            negative regulation of epithelial cell differentiation involved in kidney development + 5
            negative regulation of establishment of Sertoli cell barrier 1
            negative regulation of hepatocyte differentiation 1
            negative regulation of intestinal epithelial cell development 0
            negative regulation of lens fiber cell differentiation 1
            negative regulation of lung ciliated cell differentiation 0
            negative regulation of lung goblet cell differentiation 2
            negative regulation of pancreatic A cell differentiation 2
            negative regulation of polarized epithelial cell differentiation 0
            negative regulation of type B pancreatic cell development 1
Path 2
Term Annotations click to browse term
  biological_process 19439
    developmental process 6674
      anatomical structure development 6139
        tissue development 2068
          epithelium development 1222
            epithelial cell differentiation 668
              regulation of epithelial cell differentiation 158
                negative regulation of epithelial cell differentiation 47
                  inhibition of neuroepithelial cell differentiation + 5
                  negative regulation of border follicle cell delamination 0
                  negative regulation of border follicle cell migration 0
                  negative regulation of cumulus cell differentiation 0
                  negative regulation of endothelial cell differentiation + 11
                  negative regulation of epidermal cell differentiation + 15
                  negative regulation of epithelial cell differentiation involved in kidney development + 5
                  negative regulation of establishment of Sertoli cell barrier 1
                  negative regulation of hepatocyte differentiation 1
                  negative regulation of intestinal epithelial cell development 0
                  negative regulation of lens fiber cell differentiation 1
                  negative regulation of lung ciliated cell differentiation 0
                  negative regulation of lung goblet cell differentiation 2
                  negative regulation of pancreatic A cell differentiation 2
                  negative regulation of polarized epithelial cell differentiation 0
                  negative regulation of type B pancreatic cell development 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.