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ONTOLOGY REPORT - ANNOTATIONS


Term:Mre11 complex
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Accession:GO:0030870 term browser browse the term
Definition:Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins.
Synonyms:exact_synonym: MRN complex;   MRX complex;   RAD50-MRE11-NBN complex;   RMX complex;   Rad50 complex;   Rad50-Rad32-Nbs1 complex


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Mre11 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mre11 MRE11 homolog, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:1624291
RGD:13792537
RGD:1600115
G Mrnip MRN complex interacting protein JBrowse link 10 35,680,687 35,704,685 RGD:1624291
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1600115
RGD:13792537
RGD:1624291
G Rad50 RAD50 double strand break repair protein JBrowse link 10 39,002,130 39,054,042 RGD:68816
RGD:13792537
RGD:1624291
RGD:1600115
G Sp100 SP100 nuclear antigen JBrowse link 9 92,675,103 92,718,489 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1624291

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  cellular_component 19843
    protein-containing complex 5779
      Mre11 complex 7
Path 2
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  cellular_component 19843
    cellular anatomical entity 19457
      organelle 12557
        membrane-bounded organelle 10879
          intracellular membrane-bounded organelle 9976
            nucleus 6783
              Mre11 complex 7
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.