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ONTOLOGY REPORT - ANNOTATIONS


Term:thyroid gland development
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Accession:GO:0030878 term browser browse the term
Definition:The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.


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thyroid gland development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO MGI:MGI:97847 (MGI:MGI:3832113|PMID:18952847) RGD PMID:18952847 MGI:MGI:3832113 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide ISO MGI:MGI:1857152 (MGI:MGI:1316794|PMID:12114718) RGD PMID:12114718 MGI:MGI:1316794 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Duox2 dual oxidase 2 ISO
IEA
MGI:MGI:3712359 (MGI:MGI:3712355|PMID:17440044)
GO_REF:0000107
RGD
Ensembl
PMID:17440044 GO_REF:0000107, MGI:MGI:3712355 NCBI chr 3:114,218,187...114,237,808
Ensembl chr 3:114,218,193...114,235,933
JBrowse link
G Fgf10 fibroblast growth factor 10 ISO MGI:MGI:1859647 (MGI:MGI:3688470|PMID:11062007) RGD PMID:11062007 MGI:MGI:3688470 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Fgf8 fibroblast growth factor 8 ISO MGI:MGI:2150347|MGI:MGI:3757964|MGI:MGI:98493 (MGI:MGI:3848569|PMID:19389367) RGD PMID:19389367 MGI:MGI:3848569 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
JBrowse link
G Foxe1 forkhead box E1 ISO MGI:MGI:2181780 (MGI:MGI:1276273|PMID:9697704)
(PMID:15494458), (PMID:9697705)
RGD PMID:9697704, PMID:9697705, PMID:15494458 MGI:MGI:1276273 NCBI chr 5:61,954,549...61,957,357
Ensembl chr 5:61,954,549...61,957,357
JBrowse link
G Hesx1 HESX homeobox 1 ISO MGI:MGI:102764 (MGI:MGI:3821506|PMID:18775421) RGD PMID:18775421 MGI:MGI:3821506 NCBI chr16:2,616,538...2,636,708
Ensembl chr16:2,634,603...2,636,708
JBrowse link
G Hhex hematopoietically expressed homeobox ISO MGI:MGI:2177762 (MGI:MGI:1855906|PMID:10804184), (MGI:MGI:3522522|PMID:15581879) RGD PMID:10804184, PMID:15581879 MGI:MGI:1855906, MGI:MGI:3522522 NCBI chr 1:256,101,994...256,107,581
Ensembl chr 1:256,101,903...256,107,649
JBrowse link
G Hoxa3 homeobox A3 ISO MGI:MGI:1857992|MGI:MGI:96184|MGI:MGI:96207 (MGI:MGI:1197395|PMID:9524238), (MGI:MGI:1201272|PMID:9520319), (MGI:MGI:74186|PMID:7635047) RGD PMID:7635047, PMID:9520319, PMID:9524238 MGI:MGI:1197395, MGI:MGI:1201272, MGI:MGI:74186 NCBI chr 4:82,137,802...82,181,836
Ensembl chr 4:82,138,683...82,141,385
JBrowse link
G Hoxa5 homeo box A5 ISO MGI:MGI:2150397 (MGI:MGI:2667733|PMID:12815622) RGD PMID:12815622 MGI:MGI:2667733
G Hoxb3 homeo box B3 ISO MGI:MGI:96175 (MGI:MGI:1201272|PMID:9520319) RGD PMID:9520319 MGI:MGI:1201272 NCBI chr10:84,170,629...84,196,823
Ensembl chr10:84,182,118...84,195,796
JBrowse link
G Hoxd3 homeo box D3 ISO
IEA
MGI:MGI:96175 (MGI:MGI:1201272|PMID:9520319)
GO_REF:0000107
RGD
Ensembl
PMID:9520319 GO_REF:0000107, MGI:MGI:1201272 NCBI chr 3:61,650,569...61,670,285
Ensembl chr 3:61,658,245...61,670,282
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO
IEA
MGI:MGI:1346867 (MGI:MGI:3832113|PMID:18952847)
GO_REF:0000107
RGD
Ensembl
PMID:18952847 GO_REF:0000107, MGI:MGI:3832113 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 ISO MGI:MGI:1346866 (MGI:MGI:3832113|PMID:18952847) RGD PMID:18952847 MGI:MGI:3832113 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO MGI:MGI:1346859 (MGI:MGI:3832113|PMID:18952847) RGD PMID:18952847 MGI:MGI:3832113 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO MGI:MGI:1346858 (MGI:MGI:3832113|PMID:18952847) RGD PMID:18952847 MGI:MGI:3832113 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nkx2-1 NK2 homeobox 1 IEA
ISO
GO_REF:0000107
MGI:MGI:1857494|MGI:MGI:3653644|MGI:MGI:3653645|MGI:MGI:97492 (MGI:MGI:3522522|PMID:15581879), (MGI:MGI:3652637|PMID:16601074), (MGI:MGI:3769976|PMID:16150900)
(PMID:11854319), (PMID:15494458)
Ensembl
RGD
PMID:11854319, PMID:15494458, PMID:15581879, PMID:16150900, PMID:16601074 GO_REF:0000107, MGI:MGI:3522522, MGI:MGI:3652637, MGI:MGI:3769976 NCBI chr 6:77,418,096...77,423,383
Ensembl chr 6:77,418,096...77,421,286
JBrowse link
G Nkx2-5 NK2 homeobox 5 ISO
IEA
(PMID:16418214)
GO_REF:0000107
(MGI:MGI:3828401|PMID:16418214)
RGD
Ensembl
PMID:16418214 GO_REF:0000107, MGI:MGI:3828401 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Pax8 paired box 8 ISS
ISO
GO_REF:0000024
MGI:MGI:2156985|MGI:MGI:98742 (MGI:MGI:1203285|PMID:9590297), (MGI:MGI:2156109|PMID:11773436), (PMID:1723950)
(PMID:1337742), (PMID:15494458), (PMID:9590296)
UniProt
RGD
PMID:1337742, PMID:1723950, PMID:9590296, PMID:9590297, PMID:11773436, PMID:15494458 GO_REF:0000024, MGI:MGI:1203285, MGI:MGI:2156109 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO MGI:MGI:88190 (MGI:MGI:3832113|PMID:18952847) RGD PMID:18952847 MGI:MGI:3832113 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Shh sonic hedgehog signaling molecule ISO
IEA
MGI:MGI:1861186 (MGI:MGI:3702792|PMID:16968815)
GO_REF:0000107
RGD
Ensembl
PMID:16968815 GO_REF:0000107, MGI:MGI:3702792 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Six1 SIX homeobox 1 ISO MGI:MGI:2655195 (MGI:MGI:3624596|PMID:16530750) RGD PMID:16530750 MGI:MGI:3624596 NCBI chr 6:95,929,060...95,934,296
Ensembl chr 6:95,929,060...95,934,296
JBrowse link
G Six3 SIX homeobox 3 ISO MGI:MGI:96071 (MGI:MGI:3821506|PMID:18775421) RGD PMID:18775421 MGI:MGI:3821506 NCBI chr 6:8,886,730...8,891,094
Ensembl chr 6:8,886,591...8,889,925
JBrowse link
G Smad3 SMAD family member 3 ISO MGI:MGI:108051 (MGI:MGI:3618021|PMID:15183723) RGD PMID:15183723 MGI:MGI:3618021 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Srf serum response factor ISO MGI:MGI:3522206 (MGI:MGI:3832113|PMID:18952847) RGD PMID:18952847 MGI:MGI:3832113 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225
JBrowse link
G Tbx1 T-box transcription factor 1 ISS
ISO
GO_REF:0000024
MGI:MGI:2179136|MGI:MGI:2179191|MGI:MGI:99604 (MGI:MGI:3050165|PMID:15190012), (MGI:MGI:3697808|PMID:17164259), (MGI:MGI:3848569|PMID:19389367)
UniProt
RGD
PMID:15190012, PMID:17164259, PMID:19389367 GO_REF:0000024, MGI:MGI:3050165, MGI:MGI:3697808, MGI:MGI:3848569 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969
JBrowse link
G Tg thyroglobulin IEA
ISO
GO_REF:0000107
(PMID:15494458)
Ensembl
RGD
PMID:15494458 GO_REF:0000107 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Tgfb2 transforming growth factor, beta 2 IEP RGD PMID:18554691 RGD:2302084 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Thra thyroid hormone receptor alpha ISO
IEA
MGI:MGI:97492 (MGI:MGI:2156109|PMID:11773436)
GO_REF:0000107
RGD
Ensembl
PMID:11773436 GO_REF:0000107, MGI:MGI:2156109 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
negative regulation of thyroid gland epithelial cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir1 microRNA 1 IDA RGD PMID:21816899 RGD:10059418 NCBI chr18:2,054,933...2,055,019 JBrowse link
G Mir28 microRNA 28 IDA RGD PMID:21816899 RGD:10059418 NCBI chr11:79,380,523...79,380,608
Ensembl chr11:79,380,523...79,380,608
JBrowse link
G Mir290 microRNA 290 IDA RGD PMID:21816899 RGD:10059418 NCBI chr 1:64,538,705...64,538,785
Ensembl chr 1:64,538,705...64,538,785
JBrowse link
G Mir296 microRNA 296 IDA RGD PMID:21816899 RGD:10059418 NCBI chr 3:172,357,490...172,357,567
Ensembl chr 3:172,357,490...172,357,567
JBrowse link
G Mir297 microRNA 297 IDA RGD PMID:21816899 RGD:10059418 NCBI chr10:101,696,273...101,696,338
Ensembl chr10:101,696,273...101,696,338
JBrowse link
G Rap1gap Rap1 GTPase-activating protein IMP RGD PMID:17646383 RGD:9835038 NCBI chr 5:156,008,868...156,074,350
Ensembl chr 5:156,026,911...156,074,395
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        animal organ development 4035
          gland development 664
            thyroid gland development 35
              thyroid gland epithelial cell proliferation + 6
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            animal organ development 4035
              gland development 664
                thyroid gland development 35
                  thyroid gland epithelial cell proliferation + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.