ONTOLOGY REPORT - ANNOTATIONS


Term:mammary gland development
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Accession:GO:0030879 term browser browse the term
Definition:The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.
Synonyms:narrow_synonym: mammogenesis
 xref: MIPS_funcat:47.03.21.01
 only_in_taxon: NCBITaxon:40674 ! Mammalia


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mammary gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgap35 Rho GTPase activating protein 35 JBrowse link 1 78,456,409 78,573,374 RGD:1600115
RGD:1624291
G Arhgap5 Rho GTPase activating protein 5 JBrowse link 6 73,345,129 73,408,304 RGD:2316183
RGD:1624291
G B4galt1 beta-1,4-galactosyltransferase 1 JBrowse link 5 57,121,768 57,168,610 RGD:1624291
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:1624291
RGD:1600115
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:1599505
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:1624291
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:1624291
RGD:1600115
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:2290014
G Fasn fatty acid synthase JBrowse link 10 109,987,735 110,005,901 RGD:1624291
RGD:1600115
G Ghrhr growth hormone releasing hormone receptor JBrowse link 4 85,587,321 85,602,389 RGD:1624291
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
G Gpat4 glycerol-3-phosphate acyltransferase 4 JBrowse link 16 73,615,949 73,649,769 RGD:1624291
G Hoxa9 homeobox A9 RGD:1624291
G Hoxb9 homeo box B9 JBrowse link 10 84,119,772 84,124,963 RGD:1624291
RGD:1600115
G Hoxd9 homeo box D9 JBrowse link 3 61,620,192 61,622,360 RGD:1624291
RGD:1600115
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:1624291
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:1624291
G Irs2 insulin receptor substrate 2 JBrowse link 16 83,824,515 83,848,569 RGD:1624291
RGD:1600115
G Itga2 integrin subunit alpha 2 JBrowse link 2 46,996,904 47,097,011 RGD:2307404
G Lbh LBH regulator of WNT signaling pathway JBrowse link 6 24,154,207 24,184,217 RGD:1624291
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:1624291
RGD:13792537
RGD:1600115
G LOC103689989 prolactin-3D4 JBrowse link 17 42,920,993 42,927,704 RGD:13792537
G LOC684107 similar to placental prolactin-like protein O JBrowse link 17 38,919,078 38,928,447 RGD:13792537
G Mst1 macrophage stimulating 1 JBrowse link 8 116,857,716 116,862,286 RGD:1624291
G Muc4 mucin 4, cell surface associated JBrowse link 11 71,242,973 71,285,217 RGD:1582108
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 JBrowse link 10 81,657,152 81,666,542 RGD:1624291
G Notch4 notch receptor 4 JBrowse link 20 4,329,794 4,353,868 RGD:1624291
RGD:1600115
G Nrg3 neuregulin 3 JBrowse link 16 15,763,031 16,932,208 RGD:1624291
G Ntn1 netrin 1 JBrowse link 10 54,761,925 54,982,072 RGD:1624291
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:1624291
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:1624291
RGD:13792537
G Prl2a1 Prolactin family 2, subfamily a, member 1 JBrowse link 17 38,900,411 38,906,503 RGD:13792537
G Prl2b1 Prolactin family 2, subfamily b, member 1 JBrowse link 17 39,542,058 39,549,080 RGD:13792537
G Prl2c1 Prolactin family 2, subfamily c, member 1 JBrowse link 17 38,849,932 38,858,391 RGD:13792537
G Prl3a1 Prolactin family 3, subfamily a, member 1 JBrowse link 17 42,723,745 42,740,021 RGD:13792537
G Prl3b1 Prolactin family 3, subfamily b, member 1 JBrowse link 17 42,771,523 42,777,186 RGD:13792537
G Prl3c1 Prolactin family 3, subfamily c, member 1 JBrowse link 17 42,812,517 42,818,305 RGD:13792537
G Prl3d1 Prolactin family 3, subfamily d, member 1 JBrowse link 17 39,777,255 39,782,877 RGD:13792537
G Prl3d4 prolactin family 3, subfamily d, member 4 JBrowse link 17 39,271,883 39,278,716 RGD:13792537
G Prl4a1 prolactin family 4, subfamily a, member 1 JBrowse link 17 38,710,401 38,718,343 RGD:13792537
G Prl5a1 prolactin family 5, subfamily a, member 1 JBrowse link 17 38,323,633 38,331,051 RGD:13792537
G Prl5a2 prolactin family 5, subfamily a, member 2 JBrowse link 17 38,456,016 38,462,358 RGD:13792537
G Prl6a1 prolactin family 6, subfamily a, member 1 JBrowse link 17 42,705,730 42,710,574 RGD:13792537
G Prl7a3 prolactin family 7, subfamily a, member 3 JBrowse link 17 39,032,661 39,045,326 RGD:13792537
G Prl7a4 prolactin family 7, subfamily a, member 4 JBrowse link 17 39,095,463 39,104,519 RGD:13792537
G Prl7b1 prolactin family 7, subfamily b, member 1 JBrowse link 17 39,153,431 39,161,644 RGD:13792537
G Prl7d1 prolactin family 7, subfamily d, member 1 JBrowse link 17 38,993,183 38,999,651 RGD:13792537
G Prl8a2 prolactin family 8, subfamily a, member 2 JBrowse link 17 39,563,383 39,575,777 RGD:13792537
G Prl8a3 prolactin family 8, subfamily a, member 3 JBrowse link 17 39,455,865 39,463,715 RGD:13792537
G Prl8a4 prolactin family 8, subfamily a, member 4 JBrowse link 17 39,376,040 39,382,128 RGD:13792537
G Prl8a5 prolactin family 8, subfamily a, member 5 JBrowse link 17 39,411,716 39,417,929 RGD:13792537
G Prl8a7 prolactin family 8, subfamily a, member 7 JBrowse link 17 39,509,516 39,515,418 RGD:13792537
G Prl8a9 prolactin family 8, subfamily a, member 9 JBrowse link 17 39,241,133 39,246,941 RGD:13792537
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
G Pygo2 pygopus family PHD finger 2 JBrowse link 2 188,757,167 188,762,285 RGD:1624291
RGD:1600115
G Sox9 SRY box 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:1624291
G Tbx3 T-box 3 JBrowse link 12 42,479,518 42,494,588 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:1624291
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
RGD:1600115
branch elongation involved in mammary gland duct branching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase JBrowse link 1 265,100,094 265,270,263 RGD:1624291
RGD:1600115
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:1624291
RGD:1600115
G Csf1 colony stimulating factor 1 JBrowse link 2 210,522,370 210,550,546 RGD:1624291
G Ddr1 discoidin domain receptor tyrosine kinase 1 JBrowse link 20 3,553,430 3,574,959 RGD:1624291
RGD:1600115
G Epha2 Eph receptor A2 JBrowse link 5 159,845,773 159,874,203 RGD:1624291
RGD:1600115
G Etv4 ets variant 4 JBrowse link 10 89,685,058 89,700,300 RGD:1624291
G Kdm5b lysine demethylase 5B JBrowse link 13 51,384,371 51,455,392 RGD:1624291
RGD:1600115
G Lrp5 LDL receptor related protein 5 JBrowse link 1 218,816,833 218,920,147 RGD:1624291
RGD:13792537
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
RGD:13792537
G Msx2 msh homeobox 2 JBrowse link 17 11,683,862 11,689,527 RGD:1624291
RGD:1600115
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
RGD:1600115
G Slc12a2 solute carrier family 12 member 2 JBrowse link 18 52,917,124 52,985,281 RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
RGD:1600115
G Tbx3 T-box 3 JBrowse link 12 42,479,518 42,494,588 RGD:1624291
RGD:1600115
cell-cell signaling involved in mammary gland development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hoxa5 homeo box A5 RGD:1624291
G Lrp5 LDL receptor related protein 5 JBrowse link 1 218,816,833 218,920,147 RGD:1624291
RGD:1600115
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:1624291
RGD:1600115
G Tfap2c transcription factor AP-2 gamma JBrowse link 3 170,550,314 170,558,197 RGD:1624291
epithelial cell differentiation involved in mammary gland alveolus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxb1 forkhead box B1 JBrowse link 8 75,992,751 75,995,371 RGD:1624291
RGD:1600115
G Foxf1 forkhead box F1 JBrowse link 19 53,012,306 53,016,100 RGD:1624291
RGD:1600115
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:1624291
RGD:1600115
epithelial cell proliferation involved in mammary gland duct elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:1624291
RGD:1600115
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
RGD:1600115
G Tfap2c transcription factor AP-2 gamma JBrowse link 3 170,550,314 170,558,197 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
fibroblast growth factor receptor signaling pathway involved in mammary gland specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
lactation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:2315565
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B JBrowse link 4 22,225,123 22,307,577 RGD:2315565
G Alas2 5'-aminolevulinate synthase 2 JBrowse link X 23,167,576 23,187,356 RGD:4144779
G Aprt adenine phosphoribosyl transferase JBrowse link 19 55,387,288 55,389,256 RGD:1599204
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 JBrowse link 4 145,704,779 145,948,997 RGD:1624291
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:1599391
G Atp7b ATPase copper transporting beta JBrowse link 16 74,865,516 74,944,935 RGD:1599391
RGD:1624291
RGD:1600115
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:62398
RGD:1599445
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase JBrowse link 6 26,657,507 26,680,459 RGD:5132591
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1624291
RGD:1600115
G Cdo1 cysteine dioxygenase type 1 JBrowse link 18 40,702,027 40,716,901 RGD:2301364
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:1624291
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:1624291
RGD:1600115
G Csn2 casein beta JBrowse link 14 21,972,274 21,979,511 RGD:1624291
G Csn3 casein kappa JBrowse link 14 21,803,738 21,810,291 RGD:1624291
RGD:13792537
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:2307320
G Ddr1 discoidin domain receptor tyrosine kinase 1 JBrowse link 20 3,553,430 3,574,959 RGD:1600115
G Dhodh dihydroorotate dehydrogenase (quinone) JBrowse link 19 42,066,103 42,087,906 RGD:5132591
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:1600115
RGD:1624291
G Foxb1 forkhead box B1 JBrowse link 8 75,992,751 75,995,371 RGD:1624291
RGD:1600115
G Gc GC, vitamin D binding protein JBrowse link 14 20,267,023 20,302,577 RGD:2315536
G Ghrhr growth hormone releasing hormone receptor JBrowse link 4 85,587,321 85,602,389 RGD:1624291
RGD:1600115
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:13504863
G Gpat4 glycerol-3-phosphate acyltransferase 4 JBrowse link 16 73,615,949 73,649,769 RGD:1624291
RGD:1600115
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Hk2 hexokinase 2 JBrowse link 4 113,559,396 113,609,897 RGD:1624366
G Kalrn kalirin, RhoGEF kinase JBrowse link 11 69,484,293 70,025,682 RGD:1624291
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
RGD:1600115
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:729001
G Mt-co2 mitochondrially encoded cytochrome c oxidase II JBrowse link MT 7,006 7,689 RGD:2302300
G Mtx1 Metaxin 1 JBrowse link 2 188,522,605 188,528,747 RGD:2315565
G Muc4 mucin 4, cell surface associated JBrowse link 11 71,242,973 71,285,217 RGD:1582108
G Ncoa1 nuclear receptor coactivator 1 JBrowse link 6 28,677,563 28,931,844 RGD:5688303
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 10 48,629,121 48,772,890 RGD:5688303
G Ncor2 nuclear receptor co-repressor 2 JBrowse link 12 36,871,917 37,033,701 RGD:5688303
G Neurl1 neuralized E3 ubiquitin protein ligase 1 JBrowse link 1 266,953,006 267,038,879 RGD:1624291
RGD:1600115
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 JBrowse link 10 81,657,152 81,666,542 RGD:1624291
RGD:1600115
G Oxt oxytocin/neurophysin I prepropeptide JBrowse link 3 123,106,694 123,107,534 RGD:1579891
G Pam peptidylglycine alpha-amidating monooxygenase JBrowse link 9 111,028,543 111,177,588 RGD:2302418
G Pmch pro-melanin-concentrating hormone JBrowse link 7 28,655,206 28,656,522 RGD:1642485
G Ppat phosphoribosyl pyrophosphate amidotransferase JBrowse link 14 33,580,541 33,614,919 RGD:1599204
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:70433
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:1624291
RGD:1600115
G Rplp0 ribosomal protein lateral stalk subunit P0 JBrowse link 12 46,791,528 46,794,797 RGD:11039458
G Serpinc1 serpin family C member 1 JBrowse link 13 78,806,107 78,820,375 RGD:11035275
G Slc29a1 solute carrier family 29 member 1 JBrowse link 9 17,784,468 17,799,008 RGD:2315565
G Slc29a2 solute carrier family 29 member 2 JBrowse link 1 220,306,622 220,314,631 RGD:2315565
G Slc30a4 solute carrier family 30 member 4 JBrowse link 3 114,805,919 114,828,154 RGD:2299951
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:1624291
RGD:1600115
G Socs2 suppressor of cytokine signaling 2 JBrowse link 7 36,495,496 36,500,878 RGD:1624291
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:730121
RGD:1624291
G Stat5b signal transducer and activator of transcription 5B JBrowse link 10 88,686,207 88,712,313 RGD:1600115
RGD:1624291
G Umps uridine monophosphate synthetase JBrowse link 11 70,034,181 70,044,590 RGD:5132591
G Uprt uracil phosphoribosyltransferase homolog JBrowse link X 75,382,553 75,408,541 RGD:5132591
G Usf2 upstream transcription factor 2, c-fos interacting JBrowse link 1 89,371,798 89,383,005 RGD:1624291
RGD:1600115
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1624291
RGD:1600115
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:1624291
RGD:1600115
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1600115
RGD:1624291
lateral sprouting involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
mammary duct terminal end bud growth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:1624291
RGD:1600115
G Csf1 colony stimulating factor 1 JBrowse link 2 210,522,370 210,550,546 RGD:1624291
G Kdm5b lysine demethylase 5B JBrowse link 13 51,384,371 51,455,392 RGD:1624291
RGD:1600115
G Mst1 macrophage stimulating 1 JBrowse link 8 116,857,716 116,862,286 RGD:1624291
RGD:1600115
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1624291
G Slc12a2 solute carrier family 12 member 2 JBrowse link 18 52,917,124 52,985,281 RGD:1624291
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1624291
mammary gland alveolus development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link 7 70,360,199 70,377,422 RGD:1624291
RGD:1600115
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:1624291
RGD:1600115
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1624291
RGD:1600115
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:1624291
G Ddr1 discoidin domain receptor tyrosine kinase 1 JBrowse link 20 3,553,430 3,574,959 RGD:1624291
RGD:1600115
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:1624291
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:1600115
RGD:1624291
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Hoxa5 homeo box A5 RGD:1624291
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:1624291
RGD:1600115
G Phb2 prohibitin 2 JBrowse link 4 157,230,769 157,235,375 RGD:1624291
RGD:1600115
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:1624291
RGD:1600115
G Socs2 suppressor of cytokine signaling 2 JBrowse link 7 36,495,496 36,500,878 RGD:1624291
G Tgfa transforming growth factor alpha JBrowse link 4 117,961,877 118,045,923 RGD:1624291
RGD:1600115
G Tnfrsf11a TNF receptor superfamily member 11A JBrowse link 13 25,778,306 25,835,802 RGD:1624291
RGD:1600115
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:1624291
G Tph1 tryptophan hydroxylase 1 JBrowse link 1 102,669,868 102,699,442 RGD:1624291
RGD:1600115
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
mammary gland branching involved in pregnancy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
RGD:1600115
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1624291
RGD:1600115
mammary gland branching involved in thelarche term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:1624291
RGD:1600115
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
RGD:1600115
G Ncoa3 nuclear receptor coactivator 3 JBrowse link 3 162,692,176 162,788,582 RGD:1624291
G Phb2 prohibitin 2 JBrowse link 4 157,230,769 157,235,375 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
mammary gland bud elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pthlh parathyroid hormone-like hormone JBrowse link 4 181,663,425 181,674,181 RGD:1624291
mammary gland bud formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
RGD:1600115
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
mammary gland bud morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sostdc1 sclerostin domain containing 1 JBrowse link 6 55,812,820 55,816,994 RGD:1624291
RGD:1600115
mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Lrp5 LDL receptor related protein 5 JBrowse link 1 218,816,833 218,920,147 RGD:1624291
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:1624291
G Ntn1 netrin 1 JBrowse link 10 54,761,925 54,982,072 RGD:1624291
RGD:1600115
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
RGD:1600115
G Scrib scribble planar cell polarity protein JBrowse link 7 117,105,810 117,128,802 RGD:1624291
RGD:1600115
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1624291
mammary gland epithelial cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:1624291
RGD:1600115
G Elf5 E74 like ETS transcription factor 5 JBrowse link 3 93,333,514 93,374,454 RGD:1624291
RGD:1600115
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:1600115
RGD:1624291
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:1624291
RGD:1600115
G Hoxa5 homeo box A5 RGD:1624291
G Irf6 interferon regulatory factor 6 JBrowse link 13 111,870,121 111,889,328 RGD:1624291
RGD:1600115
G Lats1 large tumor suppressor kinase 1 JBrowse link 1 1,784,078 1,817,310 RGD:1624291
RGD:1600115
G Lbh LBH regulator of WNT signaling pathway JBrowse link 6 24,154,207 24,184,217 RGD:1624291
RGD:1600115
G Mgmt O-6-methylguanine-DNA methyltransferase JBrowse link 1 209,237,255 209,464,189 RGD:2316910
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:1624291
RGD:1600115
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
RGD:1600115
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:1600115
G Zfp703 zinc finger protein 703 JBrowse link 16 69,237,857 69,242,028 RGD:1624291
RGD:1600115
mammary gland epithelial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase JBrowse link 1 265,100,094 265,270,263 RGD:1624291
RGD:1600115
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1624291
RGD:1600115
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:1624291
RGD:1600115
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:1624291
G Epha2 Eph receptor A2 JBrowse link 5 159,845,773 159,874,203 RGD:1624291
RGD:1600115
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:1624291
RGD:1600115
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
RGD:1600115
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:1624291
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:1624291
RGD:1600115
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:1624291
mammary gland epithelium development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 JBrowse link 19 52,347,480 52,404,608 RGD:1624291
RGD:1600115
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1624291
G Msx1 msh homeobox 1 JBrowse link 14 77,712,262 77,716,061 RGD:1624291
RGD:1600115
G Msx2 msh homeobox 2 JBrowse link 17 11,683,862 11,689,527 RGD:1624291
G Orai1 ORAI calcium release-activated calcium modulator 1 JBrowse link 12 38,981,903 38,995,570 RGD:1624291
RGD:1600115
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:1624291
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:1624291
G Wnt2 Wnt family member 2 JBrowse link 4 45,286,845 45,332,899 RGD:1624291
RGD:1600115
G Wnt3 Wnt family member 3 JBrowse link 10 91,830,709 91,874,907 RGD:1624291
RGD:1600115
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
G Wnt7b Wnt family member 7B JBrowse link 7 126,423,418 126,465,724 RGD:1624291
RGD:1600115
mammary gland fat development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf1 colony stimulating factor 1 JBrowse link 2 210,522,370 210,550,546 RGD:1624291
mammary gland formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
mammary gland involution term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:4142798
G Bsx brain specific homeobox JBrowse link 8 45,061,670 45,065,430 RGD:1624291
RGD:1600115
G Capn1 calpain 1 JBrowse link 1 221,346,081 221,370,965 RGD:1624291
RGD:1600115
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Elf3 E74 like ETS transcription factor 3 JBrowse link 13 52,083,873 52,088,798 RGD:1624291
RGD:1600115
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:2290014
G Erbb3 erb-b2 receptor tyrosine kinase 3 JBrowse link 7 2,989,202 3,010,610 RGD:2290014
G Igfbp5 insulin-like growth factor binding protein 5 JBrowse link 9 80,154,230 80,166,813 RGD:1624291
RGD:1600115
G Sfrp4 secreted frizzled-related protein 4 JBrowse link 17 47,383,983 47,394,065 RGD:4107723
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:2291942
mammary gland lobule development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxb1 forkhead box B1 JBrowse link 8 75,992,751 75,995,371 RGD:1624291
RGD:1600115
mammary gland morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rln1 relaxin 1 JBrowse link 1 247,483,298 247,486,331 RGD:1624291
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:1624291
RGD:1600115
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
RGD:1600115
G Zfp157 zinc finger protein 157 JBrowse link 12 18,461,283 18,495,871 RGD:1624291
RGD:1600115
mammary gland specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
RGD:1600115
G Pax3 paired box 3 JBrowse link 9 84,004,004 84,101,226 RGD:1624291
mammary placode formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
G Nrg3 neuregulin 3 JBrowse link 16 15,763,031 16,932,208 RGD:1624291
G Tbx2 T-box 2 JBrowse link 10 73,278,932 73,290,764 RGD:1624291
G Tbx3 T-box 3 JBrowse link 12 42,479,518 42,494,588 RGD:1624291
RGD:1600115
milk ejection reflex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:1624291
RGD:1600115
negative regulation of lactation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csn2 casein beta JBrowse link 14 21,972,274 21,979,511 RGD:13792537
negative regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:1600115
RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Etv4 ets variant 4 JBrowse link 10 89,685,058 89,700,300 RGD:1624291
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
RGD:1600115
G Phb2 prohibitin 2 JBrowse link 4 157,230,769 157,235,375 RGD:1624291
RGD:1600115
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1624291
RGD:1600115
nipple development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rln1 relaxin 1 JBrowse link 1 247,483,298 247,486,331 RGD:1624291
nipple morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rxfp1 relaxin family peptide receptor 1 JBrowse link 2 178,402,411 178,520,213 RGD:1600115
RGD:1624291
nipple sheath formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pthlh parathyroid hormone-like hormone JBrowse link 4 181,663,425 181,674,181 RGD:1624291
positive regulation of apoptotic process involved in mammary gland involution term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B4galt1 beta-1,4-galactosyltransferase 1 JBrowse link 5 57,121,768 57,168,610 RGD:1624291
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1624291
RGD:1600115
positive regulation of lactation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:1624291
G LOC103689989 prolactin-3D4 JBrowse link 17 42,920,993 42,927,704 RGD:13792537
G LOC684107 similar to placental prolactin-like protein O JBrowse link 17 38,919,078 38,928,447 RGD:13792537
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:13792537
G Prl2a1 Prolactin family 2, subfamily a, member 1 JBrowse link 17 38,900,411 38,906,503 RGD:13792537
G Prl2b1 Prolactin family 2, subfamily b, member 1 JBrowse link 17 39,542,058 39,549,080 RGD:13792537
G Prl2c1 Prolactin family 2, subfamily c, member 1 JBrowse link 17 38,849,932 38,858,391 RGD:13792537
G Prl3a1 Prolactin family 3, subfamily a, member 1 JBrowse link 17 42,723,745 42,740,021 RGD:13792537
G Prl3b1 Prolactin family 3, subfamily b, member 1 JBrowse link 17 42,771,523 42,777,186 RGD:13792537
G Prl3c1 Prolactin family 3, subfamily c, member 1 JBrowse link 17 42,812,517 42,818,305 RGD:13792537
G Prl3d1 Prolactin family 3, subfamily d, member 1 JBrowse link 17 39,777,255 39,782,877 RGD:13792537
G Prl3d4 prolactin family 3, subfamily d, member 4 JBrowse link 17 39,271,883 39,278,716 RGD:13792537
G Prl4a1 prolactin family 4, subfamily a, member 1 JBrowse link 17 38,710,401 38,718,343 RGD:13792537
G Prl5a1 prolactin family 5, subfamily a, member 1 JBrowse link 17 38,323,633 38,331,051 RGD:13792537
G Prl5a2 prolactin family 5, subfamily a, member 2 JBrowse link 17 38,456,016 38,462,358 RGD:13792537
G Prl6a1 prolactin family 6, subfamily a, member 1 JBrowse link 17 42,705,730 42,710,574 RGD:13792537
G Prl7a3 prolactin family 7, subfamily a, member 3 JBrowse link 17 39,032,661 39,045,326 RGD:13792537
G Prl7a4 prolactin family 7, subfamily a, member 4 JBrowse link 17 39,095,463 39,104,519 RGD:13792537
G Prl7b1 prolactin family 7, subfamily b, member 1 JBrowse link 17 39,153,431 39,161,644 RGD:13792537
G Prl7d1 prolactin family 7, subfamily d, member 1 JBrowse link 17 38,993,183 38,999,651 RGD:13792537
G Prl8a2 prolactin family 8, subfamily a, member 2 JBrowse link 17 39,563,383 39,575,777 RGD:13792537
G Prl8a3 prolactin family 8, subfamily a, member 3 JBrowse link 17 39,455,865 39,463,715 RGD:13792537
G Prl8a4 prolactin family 8, subfamily a, member 4 JBrowse link 17 39,376,040 39,382,128 RGD:13792537
G Prl8a5 prolactin family 8, subfamily a, member 5 JBrowse link 17 39,411,716 39,417,929 RGD:13792537
G Prl8a7 prolactin family 8, subfamily a, member 7 JBrowse link 17 39,509,516 39,515,418 RGD:13792537
G Prl8a9 prolactin family 8, subfamily a, member 9 JBrowse link 17 39,241,133 39,246,941 RGD:13792537
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
RGD:1600115
positive regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link 7 70,360,199 70,377,422 RGD:1624291
RGD:1600115
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1624291
RGD:1600115
G Iqgap3 IQ motif containing GTPase activating protein 3 JBrowse link 2 187,447,477 187,489,630 RGD:1624291
RGD:1600115
G Kdm5b lysine demethylase 5B JBrowse link 13 51,384,371 51,455,392 RGD:1624291
RGD:1600115
G Mst1 macrophage stimulating 1 JBrowse link 8 116,857,716 116,862,286 RGD:1624291
RGD:13792537
G Rreb1 ras responsive element binding protein 1 JBrowse link 17 27,539,137 27,718,878 RGD:1624291
RGD:1600115
G Rtn4 reticulon 4 JBrowse link 14 114,126,931 114,174,459 RGD:1600115
RGD:1624291
G Zfp703 zinc finger protein 703 JBrowse link 16 69,237,857 69,242,028 RGD:1624291
RGD:1600115
positive regulation of mammary stem cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lbh LBH regulator of WNT signaling pathway JBrowse link 6 24,154,207 24,184,217 RGD:1624291
RGD:1600115
regulation of branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
RGD:1600115
G Etv5 ets variant 5 JBrowse link 11 82,194,657 82,252,145 RGD:1624291
RGD:1600115
G Phb2 prohibitin 2 JBrowse link 4 157,230,769 157,235,375 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
regulation of lactation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Oas2 2'-5' oligoadenylate synthetase 2 JBrowse link 12 41,341,417 41,363,124 RGD:1600115
RGD:1624291
regulation of mammary gland epithelial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Deaf1 DEAF1 transcription factor JBrowse link 1 214,283,787 214,317,466 RGD:1600115
RGD:1624291
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:1624291
RGD:1600115
G Hoxa5 homeo box A5 RGD:1624291
G Pygo2 pygopus family PHD finger 2 JBrowse link 2 188,757,167 188,762,285 RGD:1624291
RGD:1600115
tertiary branching involved in mammary gland duct morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:1624291
RGD:1600115
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17928
    developmental process 6340
      anatomical structure development 5947
        animal organ development 3843
          gland development 644
            mammary gland development 199
              cell-cell signaling involved in mammary gland development 2
              lactation + 89
              mammary gland epithelium development + 80
              mammary gland fat development + 1
              mammary gland lobule development + 22
              mammary gland morphogenesis + 62
              mammary stem cell proliferation + 1
              mesenchymal cell differentiation involved in mammary gland development 0
              negative regulation of mammary gland development in males by androgen receptor signaling pathway 0
              nipple development + 3
              thelarche + 6
Path 2
Term Annotations click to browse term
  biological_process 17928
    developmental process 6340
      anatomical structure development 5947
        multicellular organism development 5441
          system development 5022
            animal organ development 3843
              gland development 644
                mammary gland development 199
                  cell-cell signaling involved in mammary gland development 2
                  lactation + 89
                  mammary gland epithelium development + 80
                  mammary gland fat development + 1
                  mammary gland lobule development + 22
                  mammary gland morphogenesis + 62
                  mammary stem cell proliferation + 1
                  mesenchymal cell differentiation involved in mammary gland development 0
                  negative regulation of mammary gland development in males by androgen receptor signaling pathway 0
                  nipple development + 3
                  thelarche + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.