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ONTOLOGY REPORT - ANNOTATIONS


Term:retromer complex
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Accession:GO:0030904 term browser browse the term
Definition:A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.


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retromer complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankfy1 ankyrin repeat and FYVE domain containing 1 JBrowse link 10 59,259,955 59,331,669 RGD:1624291
G Dctn1 dynactin subunit 1 JBrowse link 4 114,876,770 114,896,567 RGD:1624291
G Dennd4c DENN domain containing 4C JBrowse link 5 105,100,081 105,195,634 RGD:1624291
G Dennd5a DENN domain containing 5A JBrowse link 1 174,524,047 174,588,553 RGD:1624291
G Entr1 endosome associated trafficking regulator 1 JBrowse link 3 3,827,498 3,834,219 RGD:1624291
RGD:13792537
G Magel2 MAGE family member L2 JBrowse link 1 123,015,404 123,019,945 RGD:1624291
G Rab7a RAB7A, member RAS oncogene family JBrowse link 4 119,910,461 119,963,065 RGD:1624291
G Snx1 sorting nexin 1 JBrowse link 8 71,745,687 71,786,182 RGD:1624291
G Snx12 sorting nexin 12 JBrowse link X 70,989,822 71,127,330 RGD:13792537
G Snx2 sorting nexin 2 JBrowse link 18 48,132,386 48,173,974 RGD:1624291
G Snx27 sorting nexin 27 JBrowse link 2 195,738,613 195,821,608 RGD:1600115
RGD:1624291
G Snx3 sorting nexin 3 JBrowse link 20 47,225,382 47,263,390 RGD:1624291
RGD:13792537
G Snx5 sorting nexin 5 JBrowse link 3 138,378,032 138,397,944 RGD:1624291
RGD:1600115
G Snx6 sorting nexin 6 JBrowse link 6 75,626,927 75,670,172 RGD:1624291
G Snx8 sorting nexin 8 JBrowse link 12 16,340,917 16,389,500 RGD:1624291
G Tbc1d5 TBC1 domain family, member 5 JBrowse link 9 1,144,641 1,747,732 RGD:1624291
G Trim27 tripartite motif-containing 27 JBrowse link 17 45,613,863 45,626,212 RGD:1624291
G Vps26a VPS26 retromer complex component A JBrowse link 20 32,085,465 32,115,310 RGD:10412293
RGD:1624291
RGD:13792537
G Vps26b VPS26 retromer complex component B JBrowse link 8 28,054,407 28,075,514 RGD:1624291
RGD:13792537
G Vps29 VPS29 retromer complex component JBrowse link 12 39,690,069 39,699,114 RGD:1600115
RGD:1624291
RGD:13792537
G Vps35 VPS35 retromer complex component JBrowse link 19 27,464,937 27,500,636 RGD:10412293
RGD:1624291
RGD:13792537
retromer, cargo-selective complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vps26a VPS26 retromer complex component A JBrowse link 20 32,085,465 32,115,310 RGD:1624291
G Vps29 VPS29 retromer complex component JBrowse link 12 39,690,069 39,699,114 RGD:1624291
G Vps35 VPS35 retromer complex component JBrowse link 19 27,464,937 27,500,636 RGD:1624291
retromer, tubulation complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snx1 sorting nexin 1 JBrowse link 8 71,745,687 71,786,182 RGD:1624291
G Snx2 sorting nexin 2 JBrowse link 18 48,132,386 48,173,974 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19738
    cellular anatomical entity 19354
      endomembrane system 3837
        retromer complex 21
          retromer, cargo-selective complex 3
          retromer, tubulation complex 2
Path 2
Term Annotations click to browse term
  cellular_component 19738
    cellular anatomical entity 19354
      membrane 9907
        membrane protein complex 1201
          retromer complex 21
            retromer, cargo-selective complex 3
            retromer, tubulation complex 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.