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Term:retromer, tubulation complex
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Accession:GO:0030905 term browser browse the term
Definition:The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodelling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6.
Synonyms:exact_synonym: SNX-BAR dimer;   heterodimeric membrane-deforming retromer subcomplex;   retromer complex, outer shell

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retromer, tubulation complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snx1 sorting nexin 1 JBrowse link 8 71,745,687 71,786,182 RGD:1624291
G Snx2 sorting nexin 2 JBrowse link 18 48,132,386 48,173,974 RGD:1624291

Term paths to the root
Path 1
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  cellular_component 19809
    protein-containing complex 5770
      membrane protein complex 1208
        retromer, tubulation complex 2
Path 2
Term Annotations click to browse term
  cellular_component 19809
    cellular anatomical entity 19424
      membrane 9916
        membrane protein complex 1208
          retromer complex 21
            retromer, tubulation complex 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.