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Term:retromer, cargo-selective complex
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Accession:GO:0030906 term browser browse the term
Definition:The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.
Synonyms:exact_synonym: cargo-selective retromer subcomplex;   retromer CSC;   retromer complex, inner shell;   retromer, CRC;   retromer, cargo recognition complex

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retromer, cargo-selective complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vps26a VPS26 retromer complex component A JBrowse link 20 32,085,465 32,115,310 RGD:1624291
G Vps29 VPS29 retromer complex component JBrowse link 12 39,690,069 39,699,114 RGD:1624291
G Vps35 VPS35 retromer complex component JBrowse link 19 27,464,937 27,500,636 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19843
    protein-containing complex 5779
      membrane protein complex 1210
        retromer, cargo-selective complex 3
Path 2
Term Annotations click to browse term
  cellular_component 19843
    cellular anatomical entity 19457
      membrane 9936
        membrane protein complex 1210
          retromer complex 21
            retromer, cargo-selective complex 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.