ONTOLOGY REPORT - ANNOTATIONS


Term:midbrain-hindbrain boundary development
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Accession:GO:0030917 term browser browse the term
Definition:The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.
Synonyms:exact_synonym: MHB development;   isthmic organizer development;   isthmomesencephalic boundary development;   isthmus development;   midbrain-hindbrain orgainizer development


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midbrain-hindbrain boundary development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G En1 engrailed homeobox 1 JBrowse link 13 36,532,758 36,537,888 RGD:1624291
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:1624291
G Gbx2 gastrulation brain homeobox 2 JBrowse link 9 97,063,265 97,065,855 RGD:1624291
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
RGD:13792537
G Wnt1 Wnt family member 1 JBrowse link 7 140,464,999 140,469,046 RGD:1624291
midbrain-hindbrain boundary initiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ssbp3 single stranded DNA binding protein 3 JBrowse link 5 126,511,339 126,649,830 RGD:1600115
RGD:1624291
midbrain-hindbrain boundary maturation during brain development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt1 Wnt family member 1 JBrowse link 7 140,464,999 140,469,046 RGD:1624291
RGD:1600115
midbrain-hindbrain boundary morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gbx2 gastrulation brain homeobox 2 JBrowse link 9 97,063,265 97,065,855 RGD:1624291
RGD:1600115
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Hes3 hes family bHLH transcription factor 3 JBrowse link 5 169,463,196 169,469,795 RGD:1624291
RGD:1600115
G Kdm2b lysine demethylase 2B JBrowse link 12 39,021,924 39,161,954 RGD:1624291

Term paths to the root
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Term Annotations click to browse term
  biological_process 17896
    developmental process 6323
      anatomical structure development 5930
        midbrain-hindbrain boundary development 9
          midbrain-hindbrain boundary initiation 1
          midbrain-hindbrain boundary maturation + 1
          midbrain-hindbrain boundary morphogenesis + 4
Path 2
Term Annotations click to browse term
  biological_process 17896
    developmental process 6323
      anatomical structure development 5930
        multicellular organism development 5425
          embryo development 1211
            embryo development ending in birth or egg hatching 806
              chordate embryonic development 789
                neural tube development 191
                  neural tube patterning 47
                    rostrocaudal neural tube patterning 14
                      midbrain-hindbrain boundary development 9
                        midbrain-hindbrain boundary initiation 1
                        midbrain-hindbrain boundary maturation + 1
                        midbrain-hindbrain boundary morphogenesis + 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.