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ONTOLOGY REPORT - ANNOTATIONS


Term:retrograde protein transport, ER to cytosol
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Accession:GO:0030970 term browser browse the term
Definition:The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon.
Synonyms:exact_synonym: protein dislocation from ER;   protein retrotranslocation, ER to cytosol;   retrograde protein transport, endoplasmic reticulum to cytosol


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retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aup1 AUP1, lipid droplet regulating VLDL assembly factor JBrowse link 4 113,887,030 113,890,103 RGD:1624291
RGD:1600115
G Derl1 derlin 1 JBrowse link 7 97,737,176 97,759,852 RGD:1624291
RGD:1600115
G Derl2 derlin 2 JBrowse link 10 57,641,682 57,653,554 RGD:1624291
RGD:1600115
G Erlec1 endoplasmic reticulum lectin 1 JBrowse link 14 115,314,890 115,352,871 RGD:13792537
G Faf2 Fas associated factor family member 2 JBrowse link 17 10,485,650 10,527,886 RGD:1624291
RGD:1600115
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1624291
RGD:1600115
G Hsp90b1 heat shock protein 90 beta family member 1 JBrowse link 7 27,226,570 27,240,533 RGD:1624291
RGD:1600115
G Nploc4 NPL4 homolog, ubiquitin recognition factor JBrowse link 10 109,553,518 109,610,087 RGD:1624291
RGD:1600115
G Os9 OS9, endoplasmic reticulum lectin JBrowse link 7 70,378,625 70,407,135 RGD:13792537
G Sec61b Sec61 translocon beta subunit JBrowse link 5 63,192,322 63,200,532 RGD:1624291
RGD:1600115
G Sel1l SEL1L adaptor subunit of ERAD E3 ubiquitin ligase JBrowse link 6 115,572,683 115,616,904 RGD:1624291
RGD:1600115
G Selenos selenoprotein S JBrowse link 1 126,979,579 126,989,344 RGD:1600115
RGD:13792537
RGD:1624291
G Syvn1 synoviolin 1 JBrowse link 1 221,409,281 221,416,229 RGD:1624291
RGD:13792537
G Tmem129 transmembrane protein 129 JBrowse link 14 82,350,734 82,356,084 RGD:1624291
RGD:1600115
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 JBrowse link 11 86,304,836 86,328,478 RGD:1624291
RGD:1600115
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:1624291
RGD:13792537
membrane protein proteolysis involved in retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hm13 histocompatibility minor 13 JBrowse link 3 148,150,695 148,189,623 RGD:1624291
RGD:1600115
G Rhbdd1 rhomboid domain containing 1 JBrowse link 9 88,110,731 88,229,462 RGD:1624291
RGD:1600115
negative regulation of retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Derl2 derlin 2 JBrowse link 10 57,641,682 57,653,554 RGD:1624291
RGD:1600115
G Derl3 derlin 3 JBrowse link 20 13,692,102 13,707,645 RGD:1624291
G Erlec1 endoplasmic reticulum lectin 1 JBrowse link 14 115,314,890 115,352,871 RGD:1624291
RGD:1600115
G Os9 OS9, endoplasmic reticulum lectin JBrowse link 7 70,378,625 70,407,135 RGD:1624291
RGD:1600115
G Svip small VCP interacting protein JBrowse link 1 107,368,117 107,373,807 RGD:1624291
RGD:1600115
G Ubac2 UBA domain containing 2 JBrowse link 15 108,286,407 108,433,531 RGD:1624291
RGD:1600115
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 JBrowse link 20 11,700,089 11,721,823 RGD:1624291
RGD:1600115
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 JBrowse link 5 48,274,387 48,292,699 RGD:1624291
RGD:1600115
G Yod1 YOD1 deubiquitinase JBrowse link 13 47,441,296 47,443,013 RGD:1600115
RGD:1624291
positive regulation of retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcap31 B-cell receptor-associated protein 31 JBrowse link X 157,094,365 157,126,397 RGD:1624291
RGD:1600115
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 4 140,886,644 140,918,654 RGD:1624291
RGD:1600115
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 JBrowse link 3 151,232,741 151,258,559 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    localization 6273
      cellular localization 2620
        intracellular transport 1480
          endoplasmic reticulum to cytosol transport 27
            retrograde protein transport, ER to cytosol 27
              membrane protein proteolysis involved in retrograde protein transport, ER to cytosol 2
              negative regulation of retrograde protein transport, ER to cytosol 9
              positive regulation of retrograde protein transport, ER to cytosol 3
              regulation of retrograde protein transport, ER to cytosol + 12
Path 2
Term Annotations click to browse term
  biological_process 19245
    localization 6273
      establishment of localization 4844
        transport 4705
          nitrogen compound transport 2235
            amide transport 1913
              peptide transport 1880
                protein transport 1822
                  intracellular protein transport 981
                    protein exit from endoplasmic reticulum 46
                      retrograde protein transport, ER to cytosol 27
                        membrane protein proteolysis involved in retrograde protein transport, ER to cytosol 2
                        negative regulation of retrograde protein transport, ER to cytosol 9
                        positive regulation of retrograde protein transport, ER to cytosol 3
                        regulation of retrograde protein transport, ER to cytosol + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.