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ONTOLOGY REPORT - ANNOTATIONS


Term:endocrine pancreas development
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Accession:GO:0031018 term browser browse the term
Definition:The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.


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endocrine pancreas development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 IBA (MGI:MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:MGI:6201960 NCBI chr19:20,373,434...20,390,671
Ensembl chr19:20,373,428...20,390,944
JBrowse link
G Bak1 BCL2-antagonist/killer 1 ISO RGD PMID:11000281 RGD:2315710 NCBI chr17:27,019,812...27,028,627
Ensembl chr17:27,019,810...27,029,009
JBrowse link
G Clu clusterin ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr14:65,968,483...65,981,548
Ensembl chr14:65,968,483...65,981,547
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 6:70,844,484...70,905,241
Ensembl chr 6:70,844,515...70,905,245
JBrowse link
G Foxa2 forkhead box A2 ISO
IMP
(MGI:MGI:3530180|PMID:15680365) MGI PMID:15680365 GO_REF:0000096, MGI:MGI:3530180, MGI:MGI:4834177 NCBI chr 2:148,042,877...148,046,969
Ensembl chr 2:148,042,877...148,046,969
JBrowse link
G Foxa3 forkhead box A3 TAS Reactome Reactome:R-MMU-210774 NCBI chr 7:19,013,283...19,023,539
Ensembl chr 7:19,013,284...19,023,538
JBrowse link
G Gck glucokinase TAS Reactome Reactome:R-MMU-210774 NCBI chr11:5,900,816...5,950,081
Ensembl chr11:5,900,820...5,950,081
JBrowse link
G Gip gastric inhibitory polypeptide IMP (MGI:MGI:4940930|PMID:21270265) MGI PMID:21270265 MGI:MGI:4940930 NCBI chr11:96,024,532...96,030,831
Ensembl chr11:96,024,545...96,030,831
JBrowse link
G Gipr gastric inhibitory polypeptide receptor IMP (MGI:MGI:4940930|PMID:21270265) MGI PMID:21270265 MGI:MGI:4940930 NCBI chr 7:19,156,063...19,170,248
Ensembl chr 7:19,156,061...19,166,127
JBrowse link
G Hes1 hes family bHLH transcription factor 1 TAS Reactome Reactome:R-MMU-210774 NCBI chr16:30,065,357...30,067,796
Ensembl chr16:30,064,384...30,067,796
JBrowse link
G Hnf1a HNF1 homeobox A IMP (MGI:MGI:1266996|PMID:9593777) MGI PMID:9593777 MGI:MGI:1266996 NCBI chr 5:114,948,980...114,971,062
Ensembl chr 5:114,948,980...114,971,094
JBrowse link
G Hnf1b HNF1 homeobox B ISO
TAS
MGI
Reactome
GO_REF:0000096, MGI:MGI:4834177, Reactome:R-MMU-210774 NCBI chr11:83,850,209...83,905,917
Ensembl chr11:83,850,063...83,905,819
JBrowse link
G Hnf4a hepatic nuclear factor 4, alpha TAS Reactome Reactome:R-MMU-210774 NCBI chr 2:163,506,811...163,572,907
Ensembl chr 2:163,506,808...163,572,910
JBrowse link
G Hnf4g hepatocyte nuclear factor 4, gamma TAS Reactome Reactome:R-MMU-210774 NCBI chr 3:3,508,030...3,659,800
Ensembl chr 3:3,508,030...3,658,052
JBrowse link
G Iapp islet amyloid polypeptide TAS Reactome Reactome:R-MMU-210774 NCBI chr 6:142,298,425...142,303,820
Ensembl chr 6:142,298,423...142,303,961
JBrowse link
G Il6 interleukin 6 IMP (MGI:MGI:3807360|PMID:18719127) BHF-UCL PMID:18719127 MGI:MGI:3807360 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Il6ra interleukin 6 receptor, alpha ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 3:89,869,324...89,913,196
Ensembl chr 3:89,864,059...89,913,196
JBrowse link
G Ins1 insulin I TAS Reactome Reactome:R-MMU-210774 NCBI chr19:52,264,297...52,265,015
Ensembl chr19:52,264,297...52,265,476
JBrowse link
G Insm1 insulinoma-associated 1 IMP
TAS
(MGI:MGI:3619850|PMID:16511571) MGI
Reactome
PMID:16511571 MGI:MGI:3619850, Reactome:R-MMU-210774 NCBI chr 2:146,221,997...146,225,020
Ensembl chr 2:146,221,921...146,225,020
JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 IMP
IBA
(MGI:MGI:1344214|PMID:10471501)
(MGI:MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:10471501, PMID:21873635 MGI:MGI:1344214, MGI:MGI:6201960 NCBI chr 5:29,473,823...29,478,470
Ensembl chr 5:29,473,034...29,478,470
JBrowse link
G Myt1 myelin transcription factor 1 IMP (MGI:MGI:3763794|PMID:17928203) MGI PMID:17928203 MGI:MGI:3763794 NCBI chr 2:181,763,332...181,827,775
Ensembl chr 2:181,763,332...181,827,797
JBrowse link
G Neurod1 neurogenic differentiation 1 IMP
TAS
(MGI:MGI:1096974|PMID:9308961), (MGI:MGI:1352314|PMID:10639171) BHF-UCL
Reactome
PMID:9308961, PMID:10639171 MGI:MGI:1096974, MGI:MGI:1352314, Reactome:R-MMU-210774 NCBI chr 2:79,452,637...79,456,636
Ensembl chr 2:79,452,521...79,456,751
JBrowse link
G Neurog3 neurogenin 3 IEA
TAS
UniProtKB
Reactome
GO_REF:0000002, MGI:MGI:2152098, Reactome:R-MMU-210774 NCBI chr10:62,133,090...62,134,763
Ensembl chr10:62,133,090...62,134,763
JBrowse link
G Nkx2-2 NK2 homeobox 2 IMP
TAS
(MGI:MGI:1270972|PMID:9584121) MGI
Reactome
PMID:9584121 MGI:MGI:1270972, Reactome:R-MMU-210774 NCBI chr 2:147,176,485...147,195,434
Ensembl chr 2:147,177,546...147,194,243
JBrowse link
G Nkx6-1 NK6 homeobox 1 IGI
TAS
IMP
(MGI:MGI:3579924|PMID:15944193) MGI
Reactome
PMID:15944193 MGI:MGI:3579924, Reactome:R-MMU-210774 NCBI chr 5:101,659,184...101,664,711
Ensembl chr 5:101,658,139...101,664,996
JBrowse link
G Nkx6-2 NK6 homeobox 2 IGI (MGI:MGI:3579924|PMID:15944193) MGI PMID:15944193 MGI:MGI:3579924 NCBI chr 7:139,579,376...139,582,797
Ensembl chr 7:139,579,376...139,582,797
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 TAS Reactome Reactome:R-MMU-210774 NCBI chr 1:136,842,562...136,960,448
Ensembl chr 1:136,842,571...136,960,448
JBrowse link
G Onecut1 one cut domain, family member 1 IGI
TAS
(MGI:MGI:3710726|PMID:17400205) MGI
Reactome
PMID:17400205 MGI:MGI:3710726, Reactome:R-MMU-210774 NCBI chr 9:74,861,921...74,889,648
Ensembl chr 9:74,861,921...74,891,781
JBrowse link
G Onecut2 one cut domain, family member 2 IGI (MGI:MGI:3710726|PMID:17400205) MGI PMID:17400205 MGI:MGI:3710726 NCBI chr18:64,340,032...64,398,488
Ensembl chr18:64,340,020...64,400,987
JBrowse link
G Onecut3 one cut domain, family member 3 TAS Reactome Reactome:R-MMU-210774 NCBI chr10:80,494,906...80,517,266
Ensembl chr10:80,494,835...80,517,276
JBrowse link
G Pax4 paired box 4 TAS Reactome Reactome:R-MMU-210774 NCBI chr 6:28,442,334...28,449,340
Ensembl chr 6:28,442,334...28,449,353
JBrowse link
G Pde3b phosphodiesterase 3B, cGMP-inhibited IDA (MGI:MGI:3040550|PMID:14736883) MGI PMID:14736883 MGI:MGI:3040550 NCBI chr 7:114,415,222...114,537,938
Ensembl chr 7:114,415,281...114,539,251
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IMP
TAS
(MGI:MGI:3771560|PMID:18155690) MGI
Reactome
PMID:18155690 MGI:MGI:3771560, Reactome:R-MMU-210774 NCBI chr 5:147,270,097...147,275,848
Ensembl chr 5:147,269,959...147,275,848
JBrowse link
G Pklr pyruvate kinase liver and red blood cell TAS Reactome Reactome:R-MMU-210774 NCBI chr 3:89,136,122...89,146,815
Ensembl chr 3:89,136,142...89,146,784
JBrowse link
G Ptf1a pancreas specific transcription factor, 1a TAS Reactome Reactome:R-MMU-210774 NCBI chr 2:19,445,663...19,447,501
Ensembl chr 2:19,445,663...19,447,501
JBrowse link
G Rfx3 regulatory factor X, 3 (influences HLA class II expression) IMP (MGI:MGI:3713191|PMID:17229940) UniProtKB PMID:17229940 MGI:MGI:3713191 NCBI chr19:27,761,721...28,014,669
Ensembl chr19:27,761,721...28,011,166
JBrowse link
G Rfx6 regulatory factor X, 6 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr10:51,677,760...51,730,429
Ensembl chr10:51,677,756...51,730,432
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 TAS Reactome Reactome:R-MMU-210774 NCBI chr 3:28,697,903...28,728,361
Ensembl chr 3:28,697,903...28,731,359
JBrowse link
G Sox4 SRY (sex determining region Y)-box 4 IMP (MGI:MGI:3611650|PMID:16306355) MGI PMID:16306355 MGI:MGI:3611650 NCBI chr13:28,948,919...28,953,699
Ensembl chr13:28,948,919...28,953,713
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 IMP (MGI:MGI:3815251|PMID:18723011) MGI PMID:18723011 MGI:MGI:3815251 NCBI chr11:112,782,210...112,787,757
Ensembl chr11:112,782,224...112,787,760
JBrowse link
negative regulation of pancreatic A cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes1 hes family bHLH transcription factor 1 IMP (MGI:MGI:1351379|PMID:10615124) MGI PMID:10615124 MGI:MGI:1351379 NCBI chr16:30,065,357...30,067,796
Ensembl chr16:30,064,384...30,067,796
JBrowse link
G Mir7-1 microRNA 7-1 IDA
IMP
(MGI:MGI:5437569|PMID:22764048) MGI PMID:22764048 MGI:MGI:5437569 NCBI chr13:58,392,779...58,392,886
Ensembl chr13:58,392,779...58,392,886
JBrowse link
negative regulation of type B pancreatic cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr cystic fibrosis transmembrane conductance regulator ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 6:18,170,687...18,322,770
Ensembl chr 6:18,170,687...18,322,768
JBrowse link
pancreatic A cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax6 paired box 6 IMP
ISO
(MGI:MGI:4943812|PMID:20592023) BHF-UCL
MGI
RGD
PMID:20592023 GO_REF:0000096, MGI:MGI:4417868, MGI:MGI:4834177, MGI:MGI:4943812 NCBI chr 2:105,668,896...105,698,410
Ensembl chr 2:105,668,900...105,697,364
JBrowse link
pancreatic A cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 IMP (MGI:MGI:3701716|PMID:16887115) MGI PMID:16887115 MGI:MGI:3701716 NCBI chr18:11,052,510...11,085,636
Ensembl chr18:11,052,064...11,085,635
JBrowse link
G Insm1 insulinoma-associated 1 IDA (MGI:MGI:3619850|PMID:16511571) UniProtKB PMID:16511571 MGI:MGI:3619850 NCBI chr 2:146,221,997...146,225,020
Ensembl chr 2:146,221,921...146,225,020
JBrowse link
G Pax6 paired box 6 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 2:105,668,896...105,698,410
Ensembl chr 2:105,668,900...105,697,364
JBrowse link
G Rfx6 regulatory factor X, 6 IMP (MGI:MGI:4422104|PMID:20148032) UniProtKB PMID:20148032 MGI:MGI:4422104 NCBI chr10:51,677,760...51,730,429
Ensembl chr10:51,677,756...51,730,432
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor IMP (MGI:MGI:5618205|PMID:25186293) MGI PMID:25186293 MGI:MGI:5618205 NCBI chr 6:113,623,994...113,631,634
Ensembl chr 6:113,623,959...113,631,633
JBrowse link
pancreatic A cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurod1 neurogenic differentiation 1 IGI (MGI:MGI:3768695|PMID:17988662) MGI PMID:17988662 MGI:MGI:3768695 NCBI chr 2:79,452,637...79,456,636
Ensembl chr 2:79,452,521...79,456,751
JBrowse link
G Nkx2-2 NK2 homeobox 2 IMP
IGI
(MGI:MGI:3703458|PMID:17202186)
(MGI:MGI:3768695|PMID:17988662)
MGI PMID:17202186, PMID:17988662 MGI:MGI:3703458, MGI:MGI:3768695 NCBI chr 2:147,176,485...147,195,434
Ensembl chr 2:147,177,546...147,194,243
JBrowse link
pancreatic D cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rfx6 regulatory factor X, 6 IMP (MGI:MGI:4422104|PMID:20148032) UniProtKB PMID:20148032 MGI:MGI:4422104 NCBI chr10:51,677,760...51,730,429
Ensembl chr10:51,677,756...51,730,432
JBrowse link
pancreatic epsilon cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rfx6 regulatory factor X, 6 IMP (MGI:MGI:4422104|PMID:20148032) UniProtKB PMID:20148032 MGI:MGI:4422104 NCBI chr10:51,677,760...51,730,429
Ensembl chr10:51,677,756...51,730,432
JBrowse link
pancreatic PP cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurod1 neurogenic differentiation 1 IGI (MGI:MGI:3768695|PMID:17988662) MGI PMID:17988662 MGI:MGI:3768695 NCBI chr 2:79,452,637...79,456,636
Ensembl chr 2:79,452,521...79,456,751
JBrowse link
G Nkx2-2 NK2 homeobox 2 IGI (MGI:MGI:3768695|PMID:17988662) MGI PMID:17988662 MGI:MGI:3768695 NCBI chr 2:147,176,485...147,195,434
Ensembl chr 2:147,177,546...147,194,243
JBrowse link
positive regulation of type B pancreatic cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death IMP (MGI:MGI:3778846|PMID:18223655) UniProtKB PMID:18223655 MGI:MGI:3778846 NCBI chr19:6,941,861...6,951,905
Ensembl chr19:6,941,861...6,951,899
JBrowse link
G Rfx3 regulatory factor X, 3 (influences HLA class II expression) IMP (MGI:MGI:4941444|PMID:20413507) BHF-UCL PMID:20413507 MGI:MGI:4941444 NCBI chr19:27,761,721...28,014,669
Ensembl chr19:27,761,721...28,011,166
JBrowse link
regulation of type B pancreatic cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arntl aryl hydrocarbon receptor nuclear translocator-like IMP (MGI:MGI:4819446|PMID:20562852) UniProtKB PMID:20562852 MGI:MGI:4819446 NCBI chr 7:113,178,471...113,314,126
Ensembl chr 7:113,207,465...113,314,126
JBrowse link
G Clock circadian locomotor output cycles kaput IMP (MGI:MGI:4819446|PMID:20562852) UniProtKB PMID:20562852 MGI:MGI:4819446 NCBI chr 5:76,209,868...76,305,603
Ensembl chr 5:76,209,868...76,304,792
JBrowse link
G Rheb Ras homolog enriched in brain ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 5:24,802,823...24,842,361
Ensembl chr 5:24,802,823...24,842,624
JBrowse link
type B pancreatic cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr14:46,383,525...46,390,669
Ensembl chr14:46,383,520...46,390,669
JBrowse link
G Bmp5 bone morphogenetic protein 5 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 9:75,775,365...75,900,316
Ensembl chr 9:75,775,364...75,900,310
JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr13:38,345,716...38,500,314
Ensembl chr13:38,345,107...38,500,302
JBrowse link
G Cdh2 cadherin 2 IMP (PMID:26750727) UniProt PMID:26750727 NCBI chr18:16,588,877...16,809,246
Ensembl chr18:16,588,877...16,809,246
JBrowse link
G Cdk6 cyclin-dependent kinase 6 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 5:3,341,004...3,531,008
Ensembl chr 5:3,341,485...3,531,008
JBrowse link
G Dll1 delta like canonical Notch ligand 1 IMP (MGI:MGI:5426345|PMID:22529374) UniProtKB PMID:22529374 MGI:MGI:5426345 NCBI chr17:15,367,354...15,376,932
Ensembl chr17:15,367,354...15,376,872
JBrowse link
G Hnf4a hepatic nuclear factor 4, alpha IEA UniProtKB GO_REF:0000002, MGI:MGI:2152098 NCBI chr 2:163,506,811...163,572,907
Ensembl chr 2:163,506,808...163,572,910
JBrowse link
G Insm1 insulinoma-associated 1 IMP (MGI:MGI:3655758|PMID:16951258) MGI PMID:16951258 MGI:MGI:3655758 NCBI chr 2:146,221,997...146,225,020
Ensembl chr 2:146,221,921...146,225,020
JBrowse link
G Mir214 microRNA 214 IDA (MGI:MGI:3775688|PMID:17804764) MGI PMID:17804764 MGI:MGI:3775688 NCBI chr 1:162,223,368...162,223,477
Ensembl chr 1:162,223,368...162,223,477
JBrowse link
G Mir375 microRNA 375 IDA (MGI:MGI:3775688|PMID:17804764) MGI PMID:17804764 MGI:MGI:3775688 NCBI chr 1:74,900,658...74,900,721
Ensembl chr 1:74,900,658...74,900,721
JBrowse link
G Mir503 microRNA 503 IDA (MGI:MGI:3775688|PMID:17804764) MGI PMID:17804764 MGI:MGI:3775688 NCBI chr  X:53,053,984...53,054,054
Ensembl chr  X:53,053,984...53,054,054
JBrowse link
G Mir541 microRNA 541 IDA (MGI:MGI:3775688|PMID:17804764) MGI PMID:17804764 MGI:MGI:3775688 NCBI chr12:109,742,409...109,742,498
Ensembl chr12:109,742,409...109,742,498
JBrowse link
G Nkx2-2 NK2 homeobox 2 IMP
IDA
(MGI:MGI:3703458|PMID:17202186)
(MGI:MGI:3761395|PMID:17456846)
MGI PMID:17202186, PMID:17456846 MGI:MGI:3703458, MGI:MGI:3761395 NCBI chr 2:147,176,485...147,195,434
Ensembl chr 2:147,177,546...147,194,243
JBrowse link
G Nkx6-1 NK6 homeobox 1 ISO RGD PMID:9603781 RGD:2326025 NCBI chr 5:101,659,184...101,664,711
Ensembl chr 5:101,658,139...101,664,996
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 IMP (MGI:MGI:4365695|PMID:19635472) UniProtKB PMID:19635472 MGI:MGI:4365695 NCBI chr17:24,073,680...24,155,619
Ensembl chr17:24,073,680...24,150,924
JBrowse link
G Sidt2 SID1 transmembrane family, member 2 IMP (MGI:MGI:5529865|PMID:23776622) MGI PMID:23776622 MGI:MGI:5529865 NCBI chr 9:45,937,857...45,958,000
Ensembl chr 9:45,937,857...45,955,258
JBrowse link
G Smo smoothened, frizzled class receptor IMP (MGI:MGI:4833770|PMID:20185815) MGI PMID:20185815 MGI:MGI:4833770 NCBI chr 6:29,735,497...29,761,366
Ensembl chr 6:29,735,503...29,761,365
JBrowse link
G Wnt5a wingless-type MMTV integration site family, member 5A IMP (MGI:MGI:3663526|PMID:16246260) MGI PMID:16246260 MGI:MGI:3663526 NCBI chr14:28,504,543...28,527,448
Ensembl chr14:28,504,750...28,527,448
JBrowse link
type B pancreatic cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 IMP (MGI:MGI:3701716|PMID:16887115) MGI PMID:16887115 MGI:MGI:3701716 NCBI chr18:11,052,510...11,085,636
Ensembl chr18:11,052,064...11,085,635
JBrowse link
G Insm1 insulinoma-associated 1 IDA (MGI:MGI:3619850|PMID:16511571) UniProtKB PMID:16511571 MGI:MGI:3619850 NCBI chr 2:146,221,997...146,225,020
Ensembl chr 2:146,221,921...146,225,020
JBrowse link
G Men1 multiple endocrine neoplasia 1 ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr19:6,334,979...6,340,894
Ensembl chr19:6,334,979...6,340,891
JBrowse link
G Mir7-1 microRNA 7-1 IMP
IDA
(MGI:MGI:5437569|PMID:22764048) MGI PMID:22764048 MGI:MGI:5437569 NCBI chr13:58,392,779...58,392,886
Ensembl chr13:58,392,779...58,392,886
JBrowse link
G Nkx6-1 NK6 homeobox 1 IEA UniProtKB GO_REF:0000002, MGI:MGI:2152098 NCBI chr 5:101,659,184...101,664,711
Ensembl chr 5:101,658,139...101,664,996
JBrowse link
G Pax6 paired box 6 IMP
ISO
(MGI:MGI:5437569|PMID:22764048) MGI
RGD
PMID:22764048 GO_REF:0000096, MGI:MGI:4417868, MGI:MGI:5437569 NCBI chr 2:105,668,896...105,698,410
Ensembl chr 2:105,668,900...105,697,364
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO
IBA
(MGI:MGI:6201960|PMID:21873635) MGI
GO_Central
RGD
PMID:21873635 GO_REF:0000096, MGI:MGI:4417868, MGI:MGI:4834177, MGI:MGI:6201960 NCBI chr 5:147,270,097...147,275,848
Ensembl chr 5:147,269,959...147,275,848
JBrowse link
G Rfx6 regulatory factor X, 6 IMP (MGI:MGI:4422104|PMID:20148032) UniProtKB PMID:20148032 MGI:MGI:4422104 NCBI chr10:51,677,760...51,730,429
Ensembl chr10:51,677,756...51,730,432
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor IMP (MGI:MGI:5618205|PMID:25186293) MGI PMID:25186293 MGI:MGI:5618205 NCBI chr 6:113,623,994...113,631,634
Ensembl chr 6:113,623,959...113,631,633
JBrowse link
G Zbed6 zinc finger, BED type containing 6 IMP (MGI:MGI:5511070|PMID:24043816) UniProt PMID:24043816 MGI:MGI:5511070 NCBI chr 1:133,655,879...133,660,885
Ensembl chr 1:133,655,879...133,660,885
Ensembl chr 1:133,655,879...133,660,885
JBrowse link
type B pancreatic cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-2 NK2 homeobox 2 IMP (MGI:MGI:3703458|PMID:17202186), (MGI:MGI:3768695|PMID:17988662) MGI PMID:17202186, PMID:17988662 MGI:MGI:3703458, MGI:MGI:3768695 NCBI chr 2:147,176,485...147,195,434
Ensembl chr 2:147,177,546...147,194,243
JBrowse link
type B pancreatic cell maturation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rfx3 regulatory factor X, 3 (influences HLA class II expression) IMP (MGI:MGI:4941444|PMID:20413507) BHF-UCL PMID:20413507 MGI:MGI:4941444 NCBI chr19:27,761,721...28,014,669
Ensembl chr19:27,761,721...28,011,166
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23392
    developmental process 7030
      anatomical structure development 6504
        endocrine pancreas development 65
          pancreatic A cell differentiation + 9
          pancreatic D cell differentiation + 1
          pancreatic PP cell differentiation + 2
          pancreatic epsilon cell differentiation + 1
          type B pancreatic cell differentiation + 32
Path 2
Term Annotations click to browse term
  biological_process 23392
    developmental process 7030
      anatomical structure development 6504
        multicellular organism development 5967
          system development 5379
            animal organ development 4136
              pancreas development 107
                endocrine pancreas development 65
                  pancreatic A cell differentiation + 9
                  pancreatic D cell differentiation + 1
                  pancreatic PP cell differentiation + 2
                  pancreatic epsilon cell differentiation + 1
                  type B pancreatic cell differentiation + 32
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.