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ONTOLOGY REPORT - ANNOTATIONS


Term:dsRNA processing
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Accession:GO:0031050 term browser browse the term
Definition:Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function.
Synonyms:related_synonym: double-stranded RNA fragmentation;   dsRNA fragmentation


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conversion of ds siRNA to ss siRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DICER1 dicer 1, ribonuclease III JBrowse link 14 75,709,029 75,780,779 RGD:9068941
conversion of ds siRNA to ss siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DICER1 dicer 1, ribonuclease III JBrowse link 14 75,709,029 75,780,779 RGD:9068941
negative regulation of pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCDIN3D BCDIN3 domain containing RNA methyltransferase JBrowse link 12 38,907,254 38,913,958 RGD:9068941
G LIN28B lin-28 homolog B JBrowse link 6 102,755,256 102,897,739 RGD:9068941
negative regulation of primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL6 interleukin 6 JBrowse link 7 23,415,922 23,420,767 RGD:9068941
G LIN28B lin-28 homolog B JBrowse link 6 102,755,256 102,897,739 RGD:9068941
G MECP2 methyl-CpG binding protein 2 JBrowse link X 143,571,864 143,647,192 RGD:9068941
G STAT3 signal transducer and activator of transcription 3 JBrowse link 17 14,928,689 15,003,644 RGD:9068941
negative regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ESR1 estrogen receptor 1 JBrowse link 6 149,507,599 149,918,523 RGD:9068941
G NCOR1 nuclear receptor corepressor 1 JBrowse link 17 34,934,452 35,121,195 RGD:9068941
G NCOR2 nuclear receptor corepressor 2 JBrowse link 12 121,913,368 122,155,031 RGD:9068941
G PPP3CA protein phosphatase 3 catalytic subunit alpha JBrowse link 4 93,447,095 93,770,339 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 38,324,009 38,347,003 RGD:9068941
G TNF tumor necrosis factor JBrowse link 6 31,236,650 31,239,423 RGD:9068941
G TP53 tumor protein p53 JBrowse link 17 7,699,449 7,717,812 RGD:9068941
G ZC3H10 zinc finger CCCH-type containing 10 JBrowse link 12 32,792,504 32,810,418 RGD:9068941
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 36,743,341 36,753,261 RGD:9068941
G ZMPSTE24 zinc metallopeptidase STE24 JBrowse link 1 39,545,264 39,589,721 RGD:9068941
negative regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERT telomerase reverse transcriptase JBrowse link 5 1,542,217 1,586,775 RGD:9068941
positive regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 14 34,542,132 34,549,286 RGD:9068941
G DDX5 DEAD-box helicase 5 JBrowse link 17 58,594,956 58,603,570 RGD:9068941
G EGFR epidermal growth factor receptor JBrowse link 7 55,614,042 55,807,285 RGD:9068941
G IL6 interleukin 6 JBrowse link 7 23,415,922 23,420,767 RGD:9068941
G LIN28A lin-28 homolog A JBrowse link 1 25,674,751 25,693,684 RGD:9068941
G LOC100977025 dual specificity mitogen-activated protein kinase kinase 2 JBrowse link 19 3,114,445 3,148,619 RGD:9068941
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 15 45,337,117 45,438,826 RGD:9068941
G MYOCD myocardin JBrowse link 17 38,880,120 38,983,246 RGD:9068941
G NR2F1 nuclear receptor subfamily 2 group F member 1 JBrowse link 5 21,773,283 21,785,746 RGD:9068941
G RIPK1 receptor interacting serine/threonine kinase 1 JBrowse link 6 2,893,802 2,943,162 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 38,324,009 38,347,003 RGD:9068941
G TP53 tumor protein p53 JBrowse link 17 7,699,449 7,717,812 RGD:9068941
pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAR adenosine deaminase RNA specific JBrowse link 1 129,937,993 129,983,747 RGD:9068941
G AGO1 argonaute RISC component 1 JBrowse link 1 35,148,984 35,196,252 RGD:9068941
G AGO2 argonaute RISC catalytic component 2 JBrowse link 8 137,192,037 137,308,059 RGD:9068941
G AGO4 argonaute RISC component 4 JBrowse link 1 35,072,045 35,122,418 RGD:9068941
G DICER1 dicer 1, ribonuclease III JBrowse link 14 75,709,029 75,780,779 RGD:9068941
G DROSHA drosha ribonuclease III JBrowse link 5 78,813,923 78,945,149 RGD:9068941
G LIN28A lin-28 homolog A JBrowse link 1 25,674,751 25,693,684 RGD:9068941
G LIN28B lin-28 homolog B JBrowse link 6 102,755,256 102,897,739 RGD:9068941
G LOC100968913 argonaute RISC catalytic component 3 JBrowse link 1 35,196,371 35,322,220 RGD:9068941
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 2B 65,689,029 65,708,493 RGD:9068941
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 12 35,246,937 35,253,378 RGD:9068941
G TUT4 terminal uridylyl transferase 4 JBrowse link 1 51,684,408 51,815,059 RGD:9068941
G TUT7 terminal uridylyl transferase 7 JBrowse link 9 57,433,583 57,498,675 RGD:9068941
primary miRNA methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G METTL3 methyltransferase like 3 JBrowse link 14 2,315,868 2,329,460 RGD:9068941
primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DGCR8 DGCR8 microprocessor complex subunit JBrowse link 22 2,841,041 2,872,325 RGD:9068941
G DROSHA drosha ribonuclease III JBrowse link 5 78,813,923 78,945,149 RGD:9068941
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 JBrowse link 7 26,835,881 26,846,578 RGD:9068941
G METTL3 methyltransferase like 3 JBrowse link 14 2,315,868 2,329,460 RGD:9068941
G PUS10 pseudouridine synthase 10 JBrowse link 2A 61,031,606 61,108,770 RGD:9068941
G SRRT serrate, RNA effector molecule JBrowse link 7 92,900,023 92,913,690 RGD:9068941
production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAR adenosine deaminase RNA specific JBrowse link 1 129,937,993 129,983,747 RGD:9068941
G AGO1 argonaute RISC component 1 JBrowse link 1 35,148,984 35,196,252 RGD:9068941
G AGO2 argonaute RISC catalytic component 2 JBrowse link 8 137,192,037 137,308,059 RGD:9068941
G AGO4 argonaute RISC component 4 JBrowse link 1 35,072,045 35,122,418 RGD:9068941
G DICER1 dicer 1, ribonuclease III JBrowse link 14 75,709,029 75,780,779 RGD:9068941
G LOC100968913 argonaute RISC catalytic component 3 JBrowse link 1 35,196,371 35,322,220 RGD:9068941
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 2B 65,689,029 65,708,493 RGD:9068941
G PUM1 pumilio RNA binding family member 1 JBrowse link 1 30,205,584 30,341,979 RGD:9068941
G PUM2 pumilio RNA binding family member 2 JBrowse link 2A 20,235,169 20,337,667 RGD:9068941
G RBM3 RNA binding motif protein 3 JBrowse link X 40,872,745 40,876,611 RGD:9068941
G SNIP1 Smad nuclear interacting protein 1 JBrowse link 1 36,807,488 36,827,347 RGD:9068941
G SPOUT1 SPOUT domain containing methyltransferase 1 JBrowse link 9 99,945,345 99,953,692 RGD:9068941
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 12 35,246,937 35,253,378 RGD:9068941
G TRIM71 tripartite motif containing 71 JBrowse link 3 32,745,217 32,824,985 RGD:9068941
G ZC3H7A zinc finger CCCH-type containing 7A JBrowse link 16 10,691,710 10,738,604 RGD:9068941
G ZC3H7B zinc finger CCCH-type containing 7B JBrowse link 22 22,198,403 22,256,455 RGD:9068941
production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DICER1 dicer 1, ribonuclease III JBrowse link 14 75,709,029 75,780,779 RGD:9068941
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 2B 65,689,029 65,708,493 RGD:9068941
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 12 35,246,937 35,253,378 RGD:9068941
G TERT telomerase reverse transcriptase JBrowse link 5 1,542,217 1,586,775 RGD:9068941
regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 12 35,246,937 35,253,378 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12490
    metabolic process 7937
      organic substance metabolic process 7623
        macromolecule metabolic process 6594
          gene expression 4075
            RNA processing 519
              dsRNA processing 49
                conversion of ds siRNA to ss siRNA + 1
                production of small RNA involved in gene silencing by RNA + 49
                scnRNA processing 0
Path 2
Term Annotations click to browse term
  biological_process 12490
    cellular process 11600
      cellular metabolic process 7295
        cellular nitrogen compound metabolic process 4198
          nucleobase-containing compound metabolic process 3680
            nucleic acid metabolic process 3378
              RNA metabolic process 3000
                RNA processing 519
                  dsRNA processing 49
                    conversion of ds siRNA to ss siRNA + 1
                    production of small RNA involved in gene silencing by RNA + 49
                    scnRNA processing 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.