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ONTOLOGY REPORT - ANNOTATIONS


Term:dsRNA processing
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Accession:GO:0031050 term browser browse the term
Definition:Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function.
Synonyms:related_synonym: double-stranded RNA fragmentation;   dsRNA fragmentation


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conversion of ds siRNA to ss siRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DICER1 dicer 1, ribonuclease III JBrowse link 14 95,086,228 95,158,263 RGD:2290271
conversion of ds siRNA to ss siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DICER1 dicer 1, ribonuclease III JBrowse link 14 95,086,228 95,158,263 RGD:2290271
negative regulation of pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCDIN3D BCDIN3 domain containing RNA methyltransferase JBrowse link 12 49,836,043 49,843,106 RGD:2290271
G LIN28B lin-28 homolog B JBrowse link 6 104,936,999 105,083,332 RGD:2290271
negative regulation of primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:2290271
G LIN28B lin-28 homolog B JBrowse link 6 104,936,999 105,083,332 RGD:2290271
G MECP2 methyl-CpG binding protein 2 JBrowse link X 154,021,573 154,097,717 RGD:9068941
G STAT3 signal transducer and activator of transcription 3 JBrowse link 17 42,313,324 42,388,502 RGD:2290271
negative regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ESR1 estrogen receptor 1 JBrowse link 6 151,654,148 152,129,619 RGD:2290271
G NCOR1 nuclear receptor corepressor 1 JBrowse link 17 16,029,157 16,216,475 RGD:2290271
G NCOR2 nuclear receptor corepressor 2 JBrowse link 12 124,324,415 124,567,612 RGD:2290271
G PPP3CA protein phosphatase 3 catalytic subunit alpha JBrowse link 4 101,023,418 101,348,295 RGD:2290271
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:2290271
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:2290271
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:2290271
G ZC3H10 zinc finger CCCH-type containing 10 JBrowse link 12 56,118,266 56,127,514 RGD:2290271
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 37,474,518 37,484,377 RGD:2290271
G ZMPSTE24 zinc metallopeptidase STE24 JBrowse link 1 40,258,078 40,294,180 RGD:2290271
negative regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERT telomerase reverse transcriptase JBrowse link 5 1,253,148 1,295,068 RGD:2290271
positive regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 14 53,949,736 53,956,891 RGD:2290271
G DDX5 DEAD-box helicase 5 JBrowse link 17 64,498,254 64,506,866 RGD:2290271
G EGFR epidermal growth factor receptor JBrowse link 7 55,019,017 55,211,628 RGD:2290271
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:2290271
G LIN28A lin-28 homolog A JBrowse link 1 26,410,778 26,429,728 RGD:2290271
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 15 66,386,912 66,491,544 RGD:2290271
G MAP2K2 mitogen-activated protein kinase kinase 2 JBrowse link 19 4,090,321 4,124,184 RGD:2290271
G MYCN MYCN proto-oncogene, bHLH transcription factor JBrowse link 2 15,940,550 15,947,004 RGD:2290271
G MYOCD myocardin JBrowse link 17 12,665,890 12,768,949 RGD:9068941
G NR2F1 nuclear receptor subfamily 2 group F member 1 JBrowse link 5 93,583,222 93,594,613 RGD:9068941
G RIPK1 receptor interacting serine/threonine kinase 1 JBrowse link 6 3,063,967 3,115,187 RGD:2290271
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:2290271
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:2290271
pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAR adenosine deaminase RNA specific JBrowse link 1 154,582,057 154,627,997 RGD:2290271
G AGO1 argonaute RISC component 1 JBrowse link 1 35,869,808 35,930,532 RGD:2290271
G AGO2 argonaute RISC catalytic component 2 JBrowse link 8 140,520,156 140,642,406 RGD:2290271
G AGO3 argonaute RISC catalytic component 3 JBrowse link 1 35,925,683 36,072,500 RGD:2290271
G AGO4 argonaute RISC component 4 JBrowse link 1 35,807,630 35,857,890 RGD:2290271
G DICER1 dicer 1, ribonuclease III JBrowse link 14 95,086,228 95,158,263 RGD:2290271
G DROSHA drosha ribonuclease III JBrowse link 5 31,400,494 31,532,142 RGD:2290271
G LIN28A lin-28 homolog A JBrowse link 1 26,410,778 26,429,728 RGD:2290271
G LIN28B lin-28 homolog B JBrowse link 6 104,936,999 105,083,332 RGD:2290271
G MRPL44 mitochondrial ribosomal protein L44 JBrowse link 2 223,950,846 223,967,714 RGD:2290271
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 2 178,431,414 178,451,175 RGD:2290271
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 12 53,500,921 53,506,431 RGD:2290271
G TUT4 terminal uridylyl transferase 4 JBrowse link 1 52,423,275 52,553,463 RGD:2290271
G TUT7 terminal uridylyl transferase 7 JBrowse link 9 86,287,733 86,354,497 RGD:2290271
primary miRNA methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G METTL3 methyltransferase like 3 JBrowse link 14 21,498,138 21,511,340 RGD:2290271
primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DGCR8 DGCR8 microprocessor complex subunit JBrowse link 22 20,080,232 20,111,877 RGD:2290271
G DROSHA drosha ribonuclease III JBrowse link 5 31,400,494 31,532,142 RGD:2290271
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 JBrowse link 7 26,189,920 26,200,775 RGD:2290271
G METTL3 methyltransferase like 3 JBrowse link 14 21,498,138 21,511,340 RGD:2290271
G MRPL44 mitochondrial ribosomal protein L44 JBrowse link 2 223,950,846 223,967,714 RGD:2290271
G PUS10 pseudouridine synthase 10 JBrowse link 2 60,940,218 61,019,693 RGD:2290271
G SMAD1 SMAD family member 1 JBrowse link 4 145,481,306 145,559,176 RGD:2290271
G SMAD2 SMAD family member 2 JBrowse link 18 47,808,957 47,931,188 RGD:2290271
G SMAD3 SMAD family member 3 JBrowse link 15 67,065,602 67,195,195 RGD:2290271
G SRRT serrate, RNA effector molecule JBrowse link 7 100,874,971 100,888,664 RGD:2290271
production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAR adenosine deaminase RNA specific JBrowse link 1 154,582,057 154,627,997 RGD:9068941
G AGO1 argonaute RISC component 1 JBrowse link 1 35,869,808 35,930,532 RGD:2290271
G AGO2 argonaute RISC catalytic component 2 JBrowse link 8 140,520,156 140,642,406 RGD:2290271
G AGO3 argonaute RISC catalytic component 3 JBrowse link 1 35,925,683 36,072,500 RGD:2290271
G AGO4 argonaute RISC component 4 JBrowse link 1 35,807,630 35,857,890 RGD:2290271
G DICER1 dicer 1, ribonuclease III JBrowse link 14 95,086,228 95,158,263 RGD:2290271
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 2 178,431,414 178,451,175 RGD:2290271
G PUM1 pumilio RNA binding family member 1 JBrowse link 1 30,931,506 31,065,717 RGD:2290271
G PUM2 pumilio RNA binding family member 2 JBrowse link 2 20,248,691 20,352,253 RGD:2290271
G RBM3 RNA binding motif protein 3 JBrowse link X 48,574,479 48,581,162 RGD:9068941
G SNIP1 Smad nuclear interacting protein 1 JBrowse link 1 37,534,449 37,554,293 RGD:2290271
G SPOUT1 SPOUT domain containing methyltransferase 1 JBrowse link 9 128,819,651 128,833,309 RGD:2290271
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 12 53,500,921 53,506,431 RGD:2290271
G TRIM71 tripartite motif containing 71 JBrowse link 3 32,817,997 32,897,824 RGD:2290271
G ZC3H7A zinc finger CCCH-type containing 7A JBrowse link 16 11,750,588 11,797,258 RGD:2290271
G ZC3H7B zinc finger CCCH-type containing 7B JBrowse link 22 41,301,525 41,360,147 RGD:2290271
production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGO2 argonaute RISC catalytic component 2 JBrowse link 8 140,520,156 140,642,406 RGD:2290271
G DICER1 dicer 1, ribonuclease III JBrowse link 14 95,086,228 95,158,263 RGD:2290271
G DROSHA drosha ribonuclease III JBrowse link 5 31,400,494 31,532,142 RGD:2290271
G HENMT1 HEN methyltransferase 1 JBrowse link 1 108,648,288 108,661,526 RGD:2290271
G MRPL44 mitochondrial ribosomal protein L44 JBrowse link 2 223,950,846 223,967,714 RGD:2290271
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 2 178,431,414 178,451,175 RGD:2290271
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 12 53,500,921 53,506,431 RGD:2290271
G TERT telomerase reverse transcriptase JBrowse link 5 1,253,148 1,295,068 RGD:2290271
G TSN translin JBrowse link 2 121,755,545 121,767,853 RGD:2290271
G TSNAX translin associated factor X JBrowse link 1 231,528,669 231,566,524 RGD:2290271
regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 12 53,500,921 53,506,431 RGD:2290271
regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 12 53,500,921 53,506,431 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18536
    metabolic process 12194
      organic substance metabolic process 11630
        macromolecule metabolic process 10096
          gene expression 6243
            RNA processing 985
              dsRNA processing 57
                conversion of ds siRNA to ss siRNA + 1
                production of small RNA involved in gene silencing by RNA + 57
                scnRNA processing 0
Path 2
Term Annotations click to browse term
  biological_process 18536
    cellular process 17546
      cellular metabolic process 11183
        cellular nitrogen compound metabolic process 6670
          nucleobase-containing compound metabolic process 5893
            nucleic acid metabolic process 5348
              RNA metabolic process 4824
                RNA processing 985
                  dsRNA processing 57
                    conversion of ds siRNA to ss siRNA + 1
                    production of small RNA involved in gene silencing by RNA + 57
                    scnRNA processing 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.