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ONTOLOGY REPORT - ANNOTATIONS


Term:dsRNA processing
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Accession:GO:0031050 term browser browse the term
Definition:Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function.
Synonyms:related_synonym: double-stranded RNA fragmentation;   dsRNA fragmentation


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conversion of ds siRNA to ss siRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1, ribonuclease type III JBrowse link 12 104,687,740 104,751,968 RGD:2290270
conversion of ds siRNA to ss siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1, ribonuclease type III JBrowse link 12 104,687,740 104,751,968 RGD:2290270
negative regulation of pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcdin3d BCDIN3 domain containing JBrowse link 15 99,470,084 99,474,730 RGD:2290270
G Lin28b lin-28 homolog B (C. elegans) JBrowse link 10 45,376,617 45,486,314 RGD:2290270
negative regulation of primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:2290270
G Lin28b lin-28 homolog B (C. elegans) JBrowse link 10 45,376,617 45,486,314 RGD:2290270
G Mecp2 methyl CpG binding protein 2 JBrowse link X 74,026,592 74,085,690 RGD:2290270
G Stat3 signal transducer and activator of transcription 3 JBrowse link 11 100,886,806 100,939,594 RGD:2290270
negative regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr1 estrogen receptor 1 (alpha) JBrowse link 10 4,611,989 5,005,633 RGD:2290270
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 11 62,315,663 62,457,414 RGD:2290270
G Ncor2 nuclear receptor co-repressor 2 JBrowse link 5 125,017,153 125,179,238 RGD:2290270
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform JBrowse link 3 136,669,714 136,937,727 RGD:2290270
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:2290270
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:2290270
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:2290270
G Zc3h10 zinc finger CCCH type containing 10 JBrowse link 10 128,543,560 128,548,008 RGD:2290270
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 4 125,118,414 125,127,881 RGD:2290270
G Zmpste24 zinc metallopeptidase, STE24 JBrowse link 4 121,059,237 121,098,249 RGD:2290270
negative regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tert telomerase reverse transcriptase JBrowse link 13 73,626,911 73,649,843 RGD:2290270
positive regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 14 46,383,525 46,390,669 RGD:2290270
G Ddx5 DEAD box helicase 5 JBrowse link 11 106,780,355 106,789,185 RGD:2290270
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:2290270
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:2290270
G Lin28a lin-28 homolog A (C. elegans) JBrowse link 4 134,003,330 134,019,196 RGD:2290270
G Map2k1 mitogen-activated protein kinase kinase 1 JBrowse link 9 64,185,769 64,253,605 RGD:2290270
G Map2k2 mitogen-activated protein kinase kinase 2 JBrowse link 10 81,105,913 81,124,697 RGD:2290270
G Myocd myocardin JBrowse link 11 65,173,608 65,269,989 RGD:2290270
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 JBrowse link 13 78,188,971 78,198,873 RGD:2290270
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 JBrowse link 13 34,002,225 34,035,170 RGD:2290270
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:2290270
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:2290270
pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adar adenosine deaminase, RNA-specific JBrowse link 3 89,714,469 89,753,455 RGD:2290270
G Ago1 argonaute RISC catalytic subunit 1 JBrowse link 4 126,435,012 126,468,707 RGD:2290270
G Ago2 argonaute RISC catalytic subunit 2 JBrowse link 15 73,101,625 73,184,947 RGD:2290270
G Ago3 argonaute RISC catalytic subunit 3 JBrowse link 4 126,326,994 126,431,670 RGD:2290270
G Ago4 argonaute RISC catalytic subunit 4 JBrowse link 4 126,489,487 126,533,586 RGD:2290270
G Dicer1 dicer 1, ribonuclease type III JBrowse link 12 104,687,740 104,751,968 RGD:2290270
G Drosha drosha, ribonuclease type III JBrowse link 15 12,824,804 12,935,291 RGD:2290270
G Lin28a lin-28 homolog A (C. elegans) JBrowse link 4 134,003,330 134,019,196 RGD:2290270
G Lin28b lin-28 homolog B (C. elegans) JBrowse link 10 45,376,617 45,486,314 RGD:2290270
G Mrpl44 mitochondrial ribosomal protein L44 JBrowse link 1 79,776,018 79,781,445 RGD:2290270
G Prkra protein kinase, interferon inducible double stranded RNA dependent activator JBrowse link 2 76,609,215 76,648,220 RGD:2290270
G Tarbp2 TARBP2, RISC loading complex RNA binding subunit JBrowse link 15 102,516,077 102,523,676 RGD:2290270
G Tut4 terminal uridylyl transferase 4 JBrowse link 4 108,459,410 108,559,415 RGD:2290270
G Tut7 terminal uridylyl transferase 7 JBrowse link 13 59,771,876 59,823,169 RGD:2290270
primary miRNA methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mettl3 methyltransferase like 3 JBrowse link 14 52,294,841 52,308,741 RGD:2290270
primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgcr8 DGCR8, microprocessor complex subunit JBrowse link 16 18,253,948 18,289,251 RGD:2290270
G Drosha drosha, ribonuclease type III JBrowse link 15 12,824,804 12,935,291 RGD:2290270
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 JBrowse link 6 51,460,434 51,470,048 RGD:2290270
G Mettl3 methyltransferase like 3 JBrowse link 14 52,294,841 52,308,741 RGD:2290270
G Mrpl44 mitochondrial ribosomal protein L44 JBrowse link 1 79,776,018 79,781,445 RGD:2290270
G Pus10 pseudouridylate synthase 10 JBrowse link 11 23,658,591 23,732,876 RGD:2290270
G Srrt serrate RNA effector molecule homolog (Arabidopsis) JBrowse link 5 137,295,704 137,307,716 RGD:2290270
production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adar adenosine deaminase, RNA-specific JBrowse link 3 89,714,469 89,753,455 RGD:2290270
G Ago1 argonaute RISC catalytic subunit 1 JBrowse link 4 126,435,012 126,468,707 RGD:2290270
G Ago2 argonaute RISC catalytic subunit 2 JBrowse link 15 73,101,625 73,184,947 RGD:2290270
G Ago3 argonaute RISC catalytic subunit 3 JBrowse link 4 126,326,994 126,431,670 RGD:2290270
G Ago4 argonaute RISC catalytic subunit 4 JBrowse link 4 126,489,487 126,533,586 RGD:2290270
G Dicer1 dicer 1, ribonuclease type III JBrowse link 12 104,687,740 104,751,968 RGD:2290270
G Prkra protein kinase, interferon inducible double stranded RNA dependent activator JBrowse link 2 76,609,215 76,648,220 RGD:2290270
G Pum1 pumilio RNA-binding family member 1 JBrowse link 4 130,663,238 130,781,564 RGD:2290270
G Pum2 pumilio RNA-binding family member 2 JBrowse link 12 8,674,092 8,752,583 RGD:2290270
G Rbm3 RNA binding motif (RNP1, RRM) protein 3 JBrowse link X 8,138,975 8,145,880 RGD:2290270
G Snip1 Smad nuclear interacting protein 1 JBrowse link 4 125,066,672 125,074,043 RGD:2290270
G Spout1 SPOUT domain containing methyltransferase 1 JBrowse link 2 30,173,446 30,178,494 RGD:2290270
G Tarbp2 TARBP2, RISC loading complex RNA binding subunit JBrowse link 15 102,516,077 102,523,676 RGD:2290270
G Trim71 tripartite motif-containing 71 JBrowse link 9 114,511,268 114,564,369 RGD:2290270
G Zc3h7a zinc finger CCCH type containing 7 A JBrowse link 16 11,136,594 11,176,393 RGD:2290270
G Zc3h7b zinc finger CCCH type containing 7B JBrowse link 15 81,745,098 81,796,269 RGD:2290270
production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1, ribonuclease type III JBrowse link 12 104,687,740 104,751,968 RGD:2290270
G Drosha drosha, ribonuclease type III JBrowse link 15 12,824,804 12,935,291 RGD:2290270
G Henmt1 HEN1 methyltransferase homolog 1 (Arabidopsis) JBrowse link 3 108,939,454 108,979,885 RGD:2290270
G Mrpl44 mitochondrial ribosomal protein L44 JBrowse link 1 79,776,018 79,781,445 RGD:2290270
G Prkra protein kinase, interferon inducible double stranded RNA dependent activator JBrowse link 2 76,609,215 76,648,220 RGD:2290270
G Tarbp2 TARBP2, RISC loading complex RNA binding subunit JBrowse link 15 102,516,077 102,523,676 RGD:2290270
G Tert telomerase reverse transcriptase JBrowse link 13 73,626,911 73,649,843 RGD:2290270
regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tarbp2 TARBP2, RISC loading complex RNA binding subunit JBrowse link 15 102,516,077 102,523,676 RGD:2290270
regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tarbp2 TARBP2, RISC loading complex RNA binding subunit JBrowse link 15 102,516,077 102,523,676 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23163
    metabolic process 10979
      organic substance metabolic process 10441
        macromolecule metabolic process 8964
          gene expression 5532
            RNA processing 862
              dsRNA processing 51
                conversion of ds siRNA to ss siRNA + 1
                production of small RNA involved in gene silencing by RNA + 51
                scnRNA processing 0
Path 2
Term Annotations click to browse term
  biological_process 23163
    cellular process 17053
      cellular metabolic process 9774
        cellular nitrogen compound metabolic process 5688
          nucleobase-containing compound metabolic process 4911
            nucleic acid metabolic process 4474
              RNA metabolic process 3990
                RNA processing 862
                  dsRNA processing 51
                    conversion of ds siRNA to ss siRNA + 1
                    production of small RNA involved in gene silencing by RNA + 51
                    scnRNA processing 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.