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ONTOLOGY REPORT - ANNOTATIONS


Term:dsRNA processing
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Accession:GO:0031050 term browser browse the term
Definition:Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function.
Synonyms:related_synonym: double-stranded RNA fragmentation;   dsRNA fragmentation


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conversion of ds siRNA to ss siRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DICER1 dicer 1, ribonuclease III JBrowse link 7 116,361,630 116,436,471 RGD:9068941
conversion of ds siRNA to ss siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DICER1 dicer 1, ribonuclease III JBrowse link 7 116,361,630 116,436,471 RGD:14298760
negative regulation of pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCDIN3D BCDIN3 domain containing RNA methyltransferase JBrowse link 5 15,755,307 15,761,645 RGD:14298760
G LIN28B lin-28 homolog B JBrowse link 1 71,173,291 71,296,131 RGD:9068941
negative regulation of primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL6 interleukin 6 JBrowse link 9 91,506,421 91,510,830 RGD:9068941
G LIN28B lin-28 homolog B JBrowse link 1 71,173,291 71,296,131 RGD:9068941
G MECP2 methyl-CpG binding protein 2 JBrowse link X 124,735,523 124,789,063 RGD:9068941
G STAT3 signal transducer and activator of transcription 3 JBrowse link 12 20,407,316 20,471,091 RGD:9068941
negative regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ESR1 estrogen receptor 1 JBrowse link 1 14,217,032 14,604,906 RGD:14298760
G NCOR1 nuclear receptor corepressor 1 JBrowse link 12 59,256,868 59,392,564 RGD:9068941
G NCOR2 nuclear receptor corepressor 2 JBrowse link 14 28,642,774 28,819,404 RGD:14298760
G PPP3CA protein phosphatase 3 catalytic subunit alpha JBrowse link 8 119,429,181 119,754,615 RGD:14298760
G TGFB1 transforming growth factor beta 1 JBrowse link 6 49,332,169 49,348,642 RGD:14298760
G TNF tumor necrosis factor JBrowse link 7 23,699,635 23,702,393 RGD:14298760
G TP53 tumor protein p53 JBrowse link 12 52,939,643 52,953,786 RGD:14298760
G ZC3H10 zinc finger CCCH-type containing 10 JBrowse link 5 21,506,510 21,513,972 RGD:14298760
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 6 93,541,334 93,551,200 RGD:14298760
G ZMPSTE24 zinc metallopeptidase STE24 JBrowse link 6 96,008,307 96,057,131 RGD:14298760
negative regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TERT telomerase reverse transcriptase JBrowse link 16 79,258,591 79,276,421 RGD:14298760
positive regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMP4 bone morphogenetic protein 4 JBrowse link 1 183,415,989 183,422,888 RGD:14298760
G DDX5 DEAD-box helicase 5 JBrowse link 12 14,571,712 14,580,740 RGD:14298760
G EGFR epidermal growth factor receptor JBrowse link 9 139,302,410 139,474,632 RGD:14298760
G IL6 interleukin 6 JBrowse link 9 91,506,421 91,510,830 RGD:14298760
G LIN28A lin-28 homolog A JBrowse link 6 83,806,178 83,818,550 RGD:14298760
G MAP2K1 mitogen-activated protein kinase kinase 1 JBrowse link 1 164,381,892 164,469,313 RGD:14298760
G MAP2K2 mitogen-activated protein kinase kinase 2 JBrowse link 2 74,626,739 74,651,352 RGD:9068941
G MYOCD myocardin JBrowse link 12 56,931,628 57,029,258 RGD:9068941
G NR2F1 nuclear receptor subfamily 2 group F member 1 JBrowse link 2 100,447,661 100,457,510 RGD:9068941
G RIPK1 receptor interacting serine/threonine kinase 1 JBrowse link 7 1,841,143 1,880,705 RGD:14298760
G TGFB1 transforming growth factor beta 1 JBrowse link 6 49,332,169 49,348,642 RGD:14298760
G TP53 tumor protein p53 JBrowse link 12 52,939,643 52,953,786 RGD:14298760
pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAR adenosine deaminase RNA specific JBrowse link 4 95,154,230 95,197,308 RGD:9068941
G AGO1 argonaute RISC component 1 JBrowse link 6 92,038,104 92,076,477 RGD:14298760
G AGO2 argonaute RISC catalytic component 2 JBrowse link 4 2,966,794 3,012,388 RGD:14298760
G AGO3 argonaute RISC catalytic component 3 JBrowse link 6 92,081,763 92,225,811 RGD:14298760
G AGO4 argonaute RISC component 4 JBrowse link 6 91,967,499 92,013,030 RGD:14298760
G DICER1 dicer 1, ribonuclease III JBrowse link 7 116,361,630 116,436,471 RGD:14298760
G DROSHA drosha ribonuclease III JBrowse link 16 17,727,695 17,847,954 RGD:14298760
G LIN28A lin-28 homolog A JBrowse link 6 83,806,178 83,818,550 RGD:14298760
G LIN28B lin-28 homolog B JBrowse link 1 71,173,291 71,296,131 RGD:9068941
G MRPL44 mitochondrial ribosomal protein L44 JBrowse link 15 125,732,419 125,739,819 RGD:14298760
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 15 84,134,273 84,156,596 RGD:14298760
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 5 18,718,588 18,723,843 RGD:14298760
G TUT4 terminal uridylyl transferase 4 JBrowse link 6 159,655,658 159,794,450 RGD:14298760
G TUT7 terminal uridylyl transferase 7 JBrowse link 10 28,995,564 29,061,179 RGD:14298760
primary miRNA methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G METTL3 methyltransferase like 3 JBrowse link 7 77,661,945 77,679,459 RGD:14298760
primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DGCR8 DGCR8 microprocessor complex subunit JBrowse link 14 51,473,512 51,489,535 RGD:14298760
G DROSHA drosha ribonuclease III JBrowse link 16 17,727,695 17,847,954 RGD:14298760
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 JBrowse link 18 46,205,164 46,215,861 RGD:14298760
G METTL3 methyltransferase like 3 JBrowse link 7 77,661,945 77,679,459 RGD:9068941
G MRPL44 mitochondrial ribosomal protein L44 JBrowse link 15 125,732,419 125,739,819 RGD:14298760
G PUS10 pseudouridine synthase 10 JBrowse link 3 80,791,244 80,863,773 RGD:14298760
G SRRT serrate, RNA effector molecule JBrowse link 3 8,717,782 8,731,204 RGD:14298760
production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADAR adenosine deaminase RNA specific JBrowse link 4 95,154,230 95,197,308 RGD:9068941
G AGO1 argonaute RISC component 1 JBrowse link 6 92,038,104 92,076,477 RGD:9068941
G AGO2 argonaute RISC catalytic component 2 JBrowse link 4 2,966,794 3,012,388 RGD:9068941
G AGO3 argonaute RISC catalytic component 3 JBrowse link 6 92,081,763 92,225,811 RGD:9068941
G AGO4 argonaute RISC component 4 JBrowse link 6 91,967,499 92,013,030 RGD:9068941
G DICER1 dicer 1, ribonuclease III JBrowse link 7 116,361,630 116,436,471 RGD:9068941
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 15 84,134,273 84,156,596 RGD:9068941
G PUM1 pumilio RNA binding family member 1 JBrowse link 6 87,546,388 87,687,483 RGD:14298760
G PUM2 pumilio RNA binding family member 2 JBrowse link 3 117,857,930 117,965,564 RGD:14298760
G RBM3 RNA binding motif protein 3 JBrowse link X 42,704,019 42,707,587 RGD:9068941
G SNIP1 Smad nuclear interacting protein 1 JBrowse link 6 93,597,050 93,612,169 RGD:14298760
G SPOUT1 SPOUT domain containing methyltransferase 1 JBrowse link 1 269,157,173 269,167,154 RGD:14298760
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 5 18,718,588 18,723,843 RGD:9068941
G TRIM71 tripartite motif containing 71 JBrowse link 13 18,762,043 18,835,788 RGD:14298760
G ZC3H7A zinc finger CCCH-type containing 7A JBrowse link 3 31,332,486 31,372,802 RGD:14298760
G ZC3H7B zinc finger CCCH-type containing 7B JBrowse link 5 7,148,624 7,201,429 RGD:14298760
production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DICER1 dicer 1, ribonuclease III JBrowse link 7 116,361,630 116,436,471 RGD:14298760
G DROSHA drosha ribonuclease III JBrowse link 16 17,727,695 17,847,954 RGD:14298760
G HENMT1 HEN methyltransferase 1 JBrowse link 4 111,364,456 111,382,582 RGD:14298760
G MRPL44 mitochondrial ribosomal protein L44 JBrowse link 15 125,732,419 125,739,819 RGD:14298760
G PRKRA protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 15 84,134,273 84,156,596 RGD:14298760
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 5 18,718,588 18,723,843 RGD:14298760
G TERT telomerase reverse transcriptase JBrowse link 16 79,258,591 79,276,421 RGD:14298760
regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 5 18,718,588 18,723,843 RGD:14298760
regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TARBP2 TARBP2 subunit of RISC loading complex JBrowse link 5 18,718,588 18,723,843 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16412
    metabolic process 10433
      organic substance metabolic process 9899
        macromolecule metabolic process 8604
          gene expression 5208
            RNA processing 785
              dsRNA processing 51
                conversion of ds siRNA to ss siRNA + 1
                production of small RNA involved in gene silencing by RNA + 51
                scnRNA processing 0
Path 2
Term Annotations click to browse term
  biological_process 16412
    cellular process 15624
      cellular metabolic process 9424
        cellular nitrogen compound metabolic process 5498
          nucleobase-containing compound metabolic process 4795
            nucleic acid metabolic process 4388
              RNA metabolic process 3922
                RNA processing 785
                  dsRNA processing 51
                    conversion of ds siRNA to ss siRNA + 1
                    production of small RNA involved in gene silencing by RNA + 51
                    scnRNA processing 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.