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ONTOLOGY REPORT - ANNOTATIONS


Term:dsRNA processing
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Accession:GO:0031050 term browser browse the term
Definition:Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function.
Synonyms:related_synonym: double-stranded RNA fragmentation;   dsRNA fragmentation


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conversion of ds siRNA to ss siRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
conversion of ds siRNA to ss siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
negative regulation of pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcdin3d BCDIN3 domain containing RNA methyltransferase JBrowse link 7 141,132,106 141,136,700 RGD:1624291
RGD:13792537
RGD:1600115
G Lin28b lin-28 homolog B JBrowse link 20 50,482,536 50,580,273 RGD:1624291
negative regulation of primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Lin28b lin-28 homolog B JBrowse link 20 50,482,536 50,580,273 RGD:1624291
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:12789709
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:1624291
negative regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:1624291
RGD:1600115
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 10 48,629,121 48,772,890 RGD:1624291
RGD:1600115
G Ncor2 nuclear receptor co-repressor 2 JBrowse link 12 36,871,917 37,033,701 RGD:1624291
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
G Zc3h10 zinc finger CCCH type containing 10 JBrowse link 7 2,968,428 2,972,521 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
G Zmpste24 zinc metallopeptidase STE24 JBrowse link 5 139,982,404 140,015,541 RGD:1624291
negative regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:1624291
positive regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Ddx5 DEAD-box helicase 5 JBrowse link 10 94,979,759 94,988,461 RGD:1624291
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Lin28a lin-28 homolog A JBrowse link 5 152,230,343 152,247,873 RGD:1624291
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:1624291
RGD:1600115
G Map2k2 mitogen activated protein kinase kinase 2 JBrowse link 7 11,458,971 11,478,520 RGD:1624291
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1624291
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 JBrowse link 2 5,569,954 5,579,894 RGD:1624291
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adar adenosine deaminase, RNA-specific JBrowse link 2 189,045,551 189,085,448 RGD:1624291
RGD:1600115
G Ago1 argonaute RISC component 1 JBrowse link 5 144,444,390 144,479,430 RGD:1624291
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:1624291
RGD:1600115
G Ago3 argonaute RISC catalytic component 3 JBrowse link 5 144,355,792 144,436,509 RGD:1624291
G Ago4 argonaute RISC component 4 JBrowse link 5 144,501,875 144,557,165 RGD:1624291
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
RGD:13792537
G Drosha drosha ribonuclease III JBrowse link 2 62,887,267 63,000,307 RGD:1624291
RGD:13792537
G Lin28a lin-28 homolog A JBrowse link 5 152,230,343 152,247,873 RGD:1624291
G Lin28b lin-28 homolog B JBrowse link 20 50,482,536 50,580,273 RGD:1624291
G Mrpl44 mitochondrial ribosomal protein L44 JBrowse link 9 85,542,763 85,547,814 RGD:13792537
G Prkra protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 3 63,489,081 63,507,918 RGD:1600115
RGD:1624291
G Tarbp2 TARBP2 subunit of RISC loading complex JBrowse link 7 144,121,688 144,126,860 RGD:1600115
RGD:1624291
G Tut4 terminal uridylyl transferase 4 JBrowse link 5 128,063,880 128,168,726 RGD:1624291
RGD:13792537
G Tut7 terminal uridylyl transferase 7 JBrowse link 17 5,225,854 5,279,674 RGD:1624291
RGD:13792537
primary miRNA methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mettl3 methyltransferase-like 3 JBrowse link 15 28,710,299 28,721,491 RGD:1624291
RGD:13792537
primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgcr8 DGCR8 microprocessor complex subunit JBrowse link 11 86,852,682 86,885,233 RGD:1624291
RGD:13792537
G Drosha drosha ribonuclease III JBrowse link 2 62,887,267 63,000,307 RGD:1624291
RGD:13792537
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 JBrowse link 4 81,237,496 81,241,281 RGD:1600115
RGD:1624291
G Mettl3 methyltransferase-like 3 JBrowse link 15 28,710,299 28,721,491 RGD:1624291
G Mrpl44 mitochondrial ribosomal protein L44 JBrowse link 9 85,542,763 85,547,814 RGD:13792537
G Pus10 pseudouridine synthase 10 JBrowse link 14 108,411,941 108,479,696 RGD:1624291
G Srrt serrate, RNA effector molecule JBrowse link 12 22,457,898 22,471,090 RGD:1624291
production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adar adenosine deaminase, RNA-specific JBrowse link 2 189,045,551 189,085,448 RGD:1624291
G Ago1 argonaute RISC component 1 JBrowse link 5 144,444,390 144,479,430 RGD:1624291
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:1624291
G Ago3 argonaute RISC catalytic component 3 JBrowse link 5 144,355,792 144,436,509 RGD:1624291
G Ago4 argonaute RISC component 4 JBrowse link 5 144,501,875 144,557,165 RGD:1624291
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
G NEWGENE_1359268 Smad nuclear interacting protein 1 JBrowse link 5 143,063,206 143,070,899 RGD:1600115
RGD:13792537
G Prkra protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 3 63,489,081 63,507,918 RGD:1624291
G Pum1 pumilio RNA-binding family member 1 JBrowse link 5 148,781,239 148,911,776 RGD:1624291
RGD:13792537
G Pum2 pumilio RNA-binding family member 2 JBrowse link 6 33,786,184 33,865,693 RGD:1624291
RGD:13792537
G Rbm3 RNA binding motif protein 3 JBrowse link X 15,098,880 15,102,344 RGD:1624291
G Snip1 Smad nuclear interacting protein 1 JBrowse link 15 19,275,273 19,282,753 RGD:1624291
RGD:13792537
RGD:1600115
G Spout1 SPOUT domain containing methyltransferase 1 JBrowse link 3 8,743,890 8,751,634 RGD:1624291
RGD:13792537
G Tarbp2 TARBP2 subunit of RISC loading complex JBrowse link 7 144,121,688 144,126,860 RGD:1624291
G Trim71 tripartite motif containing 71 JBrowse link 8 122,553,015 122,604,787 RGD:1624291
RGD:1600115
G Zc3h7a zinc finger CCCH type containing 7 A JBrowse link 10 4,535,651 4,575,643 RGD:1624291
RGD:13792537
G Zc3h7b zinc finger CCCH-type containing 7B JBrowse link 7 122,978,999 123,027,166 RGD:1624291
RGD:13792537
production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07012856.1 RGD:13792537
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
RGD:13792537
G Drosha drosha ribonuclease III JBrowse link 2 62,887,267 63,000,307 RGD:13792537
G Henmt1 HEN methyltransferase 1 JBrowse link 2 211,740,571 211,753,718 RGD:13792537
G Mrpl44 mitochondrial ribosomal protein L44 JBrowse link 9 85,542,763 85,547,814 RGD:13792537
G Prkra protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 3 63,489,081 63,507,918 RGD:1600115
RGD:1624291
G Tarbp2 TARBP2 subunit of RISC loading complex JBrowse link 7 144,121,688 144,126,860 RGD:1600115
RGD:1624291
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:1624291
regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tarbp2 TARBP2 subunit of RISC loading complex JBrowse link 7 144,121,688 144,126,860 RGD:1624291
regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tarbp2 TARBP2 subunit of RISC loading complex JBrowse link 7 144,121,688 144,126,860 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12097
      organic substance metabolic process 11495
        macromolecule metabolic process 9944
          gene expression 6164
            RNA processing 917
              dsRNA processing 53
                conversion of ds siRNA to ss siRNA + 1
                production of small RNA involved in gene silencing by RNA + 53
                scnRNA processing 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      cellular metabolic process 10918
        cellular nitrogen compound metabolic process 6542
          nucleobase-containing compound metabolic process 5344
            nucleic acid metabolic process 4850
              RNA metabolic process 4347
                RNA processing 917
                  dsRNA processing 53
                    conversion of ds siRNA to ss siRNA + 1
                    production of small RNA involved in gene silencing by RNA + 53
                    scnRNA processing 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.