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ONTOLOGY REPORT - ANNOTATIONS


Term:dsRNA processing
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Accession:GO:0031050 term browser browse the term
Definition:Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function.
Synonyms:related_synonym: double-stranded RNA fragmentation;   dsRNA fragmentation


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conversion of ds siRNA to ss siRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1, ribonuclease III JBrowse link NW_004936846 528,768 584,599 RGD:9068941
conversion of ds siRNA to ss siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1, ribonuclease III JBrowse link NW_004936846 528,768 584,599 RGD:9068941
negative regulation of pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcdin3d BCDIN3 domain containing RNA methyltransferase JBrowse link NW_004936512 7,516,324 7,521,063 RGD:9068941
G Lin28b lin-28 homolog B JBrowse link NW_004936564 1,646,469 1,768,879 RGD:9068941
negative regulation of primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lin28b lin-28 homolog B JBrowse link NW_004936564 1,646,469 1,768,879 RGD:9068941
G Mecp2 methyl-CpG binding protein 2 JBrowse link NW_004936809 902,938 967,771 RGD:9068941
G Stat3 signal transducer and activator of transcription 3 JBrowse link NW_004936490 17,119,189 17,178,402 RGD:9068941
negative regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esr1 estrogen receptor 1 JBrowse link NW_004936489 4,616,839 4,887,179 RGD:9068941
G Ncor1 nuclear receptor corepressor 1 JBrowse link NW_004936821 382,756 538,254 RGD:9068941
G Ncor2 nuclear receptor corepressor 2 JBrowse link NW_004936558 658,723 775,263 RGD:9068941
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link NW_004936520 1,987,989 2,146,473 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004936661 3,742,080 3,758,266 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004936727 1,936,066 1,937,766 RGD:9068941
G Tp53 tumor protein p53 JBrowse link NW_004936595 919,807 935,367 RGD:9068941
G Zc3h10 zinc finger CCCH-type containing 10 JBrowse link NW_004936646 528,455 534,267 RGD:9068941
G Zc3h12a zinc finger CCCH-type containing 12A JBrowse link NW_004936474 19,714,145 19,722,512 RGD:9068941
G Zmpste24 zinc metallopeptidase STE24 JBrowse link NW_004936474 22,035,059 22,077,846 RGD:9068941
negative regulation of production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tert telomerase reverse transcriptase JBrowse link NW_004936815 468,987 492,666 RGD:9068941
positive regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link NW_004936697 1,054,237 1,061,468 RGD:9068941
G Ddx5 DEAD-box helicase 5 JBrowse link NW_004936541 5,005,211 5,013,439 RGD:9068941
G Egfr epidermal growth factor receptor JBrowse link NW_004936678 365,005 560,546 RGD:9068941
G Lin28a lin-28 homolog A JBrowse link NW_004936474 10,896,153 10,909,247 RGD:9068941
G Map2k1 mitogen-activated protein kinase kinase 1 JBrowse link NW_004936471 26,589,251 26,628,302 RGD:9068941
G Map2k2 mitogen-activated protein kinase kinase 2 JBrowse link NW_004936588 2,338,127 2,377,090 RGD:9068941
G Myocd myocardin JBrowse link NW_004936595 5,256,615 5,356,563 RGD:9068941
G Nr2f1 nuclear receptor subfamily 2 group F member 1 JBrowse link NW_004936523 9,508,204 9,517,266 RGD:9068941
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link NW_004936534 9,326,307 9,361,943 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004936661 3,742,080 3,758,266 RGD:9068941
G Tp53 tumor protein p53 JBrowse link NW_004936595 919,807 935,367 RGD:9068941
pre-miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adar adenosine deaminase RNA specific JBrowse link NW_004936580 4,183,016 4,208,341 RGD:9068941
G Ago2 argonaute RISC catalytic component 2 JBrowse link NW_004936470 10,641,109 10,690,587 RGD:9068941
G Ago4 argonaute RISC component 4 JBrowse link NW_004936474 18,335,536 18,371,398 RGD:9068941
G Dicer1 dicer 1, ribonuclease III JBrowse link NW_004936846 528,768 584,599 RGD:9068941
G Drosha drosha ribonuclease III JBrowse link NW_004936518 9,100,094 9,218,405 RGD:9068941
G Lin28a lin-28 homolog A JBrowse link NW_004936474 10,896,153 10,909,247 RGD:9068941
G Lin28b lin-28 homolog B JBrowse link NW_004936564 1,646,469 1,768,879 RGD:9068941
G Prkra protein activator of interferon induced protein kinase EIF2AK2 JBrowse link NW_004936509 7,653,192 7,668,925 RGD:9068941
G Tarbp2 TARBP2 subunit of RISC loading complex JBrowse link NW_004936512 10,774,793 10,780,041 RGD:9068941
G Tut4 terminal uridylyl transferase 4 JBrowse link NW_004936522 8,468,092 8,560,453 RGD:9068941
G Tut7 terminal uridylyl transferase 7 JBrowse link NW_004936680 1,693,815 1,753,641 RGD:9068941
primary miRNA methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mettl3 methyltransferase like 3 JBrowse link NW_004936880 646,835 661,312 RGD:9068941
primary miRNA processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgcr8 DGCR8 microprocessor complex subunit JBrowse link NW_004936619 3,977,307 4,014,490 RGD:9068941
G Drosha drosha ribonuclease III JBrowse link NW_004936518 9,100,094 9,218,405 RGD:9068941
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 JBrowse link NW_004936478 2,970,261 2,980,277 RGD:9068941
G Mettl3 methyltransferase like 3 JBrowse link NW_004936880 646,835 661,312 RGD:9068941
G Pus10 pseudouridine synthase 10 JBrowse link NW_004936491 6,439,248 6,530,309 RGD:9068941
G Srrt serrate, RNA effector molecule JBrowse link NW_004936543 843,144 855,491 RGD:9068941
production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adar adenosine deaminase RNA specific JBrowse link NW_004936580 4,183,016 4,208,341 RGD:9068941
G Ago2 argonaute RISC catalytic component 2 JBrowse link NW_004936470 10,641,109 10,690,587 RGD:9068941
G Ago4 argonaute RISC component 4 JBrowse link NW_004936474 18,335,536 18,371,398 RGD:9068941
G Dicer1 dicer 1, ribonuclease III JBrowse link NW_004936846 528,768 584,599 RGD:9068941
G Prkra protein activator of interferon induced protein kinase EIF2AK2 JBrowse link NW_004936509 7,653,192 7,668,925 RGD:9068941
G Pum1 pumilio RNA binding family member 1 JBrowse link NW_004936474 14,243,325 14,363,461 RGD:9068941
G Pum2 pumilio RNA binding family member 2 JBrowse link NW_004936493 11,067,318 11,154,133 RGD:9068941
G Rbm3 RNA binding motif protein 3 JBrowse link NW_004936721 547,751 551,273 RGD:9068941
G Snip1 Smad nuclear interacting protein 1 JBrowse link NW_004936474 19,760,653 19,778,224 RGD:9068941
G Spout1 SPOUT domain containing methyltransferase 1 JBrowse link NW_004936487 16,284,921 16,291,572 RGD:9068941
G Tarbp2 TARBP2 subunit of RISC loading complex JBrowse link NW_004936512 10,774,793 10,780,041 RGD:9068941
G Trim71 tripartite motif containing 71 JBrowse link NW_004936473 23,223,984 23,290,177 RGD:9068941
G Zc3h7a zinc finger CCCH-type containing 7A JBrowse link NW_004936530 9,558,395 9,581,337 RGD:9068941
G Zc3h7b zinc finger CCCH-type containing 7B JBrowse link NW_004936492 532,883 584,142 RGD:9068941
production of siRNA involved in RNA interference term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1, ribonuclease III JBrowse link NW_004936846 528,768 584,599 RGD:9068941
G Prkra protein activator of interferon induced protein kinase EIF2AK2 JBrowse link NW_004936509 7,653,192 7,668,925 RGD:9068941
G Tarbp2 TARBP2 subunit of RISC loading complex JBrowse link NW_004936512 10,774,793 10,780,041 RGD:9068941
G Tert telomerase reverse transcriptase JBrowse link NW_004936815 468,987 492,666 RGD:9068941
regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tarbp2 TARBP2 subunit of RISC loading complex JBrowse link NW_004936512 10,774,793 10,780,041 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11931
    metabolic process 7629
      organic substance metabolic process 7327
        macromolecule metabolic process 6361
          gene expression 3921
            RNA processing 509
              dsRNA processing 46
                conversion of ds siRNA to ss siRNA + 1
                production of small RNA involved in gene silencing by RNA + 46
                scnRNA processing 0
Path 2
Term Annotations click to browse term
  biological_process 11931
    cellular process 11113
      cellular metabolic process 7037
        cellular nitrogen compound metabolic process 4061
          nucleobase-containing compound metabolic process 3564
            nucleic acid metabolic process 3279
              RNA metabolic process 2909
                RNA processing 509
                  dsRNA processing 46
                    conversion of ds siRNA to ss siRNA + 1
                    production of small RNA involved in gene silencing by RNA + 46
                    scnRNA processing 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.