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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of histone modification
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Accession:GO:0031058 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the covalent alteration of a histone.
Synonyms:exact_synonym: up regulation of histone modification;   upregulation of histone modification
 narrow_synonym: activation of histone modification;   stimulation of histone modification


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positive regulation of histone modification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ube2n ubiquitin-conjugating enzyme E2N JBrowse link 7 36,610,147 36,640,190 RGD:1624291
positive regulation of histone acetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Arid5a AT-rich interaction domain 5A JBrowse link 9 42,871,907 42,886,725 RGD:1624291
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1624291
RGD:13792537
G Brd7 bromodomain containing 7 JBrowse link 19 19,672,780 19,701,484 RGD:1624291
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:9588307
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Glyr1 glyoxylate reductase 1 homolog JBrowse link 10 10,725,830 10,759,471 RGD:1624291
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
G Kat2a lysine acetyltransferase 2A JBrowse link 10 88,611,586 88,619,558 RGD:8693751
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:1624291
G Nap1l2 nucleosome assembly protein 1-like 2 JBrowse link X 73,997,274 73,999,677 RGD:1624291
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:1624291
RGD:1600115
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
G Rps6ka4 ribosomal protein S6 kinase A4 JBrowse link 1 222,087,328 222,098,284 RGD:1624291
G Rps6ka5 ribosomal protein S6 kinase A5 JBrowse link 6 124,557,892 124,735,787 RGD:1624291
G Ruvbl2 RuvB-like AAA ATPase 2 JBrowse link 1 101,413,766 101,426,970 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
G Tada2a transcriptional adaptor 2A JBrowse link 10 71,393,701 71,441,435 RGD:13792537
G Tada2b transcriptional adaptor 2B JBrowse link 14 79,446,057 79,457,341 RGD:13792537
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
positive regulation of histone deacetylase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:1624291
G Prkd1 protein kinase D1 JBrowse link 6 71,035,017 71,349,531 RGD:1624291
G Prkd2 protein kinase D2 JBrowse link 1 78,767,911 78,796,223 RGD:1624291
G RGD735065 similar to GI:13385412-like protein splice form I JBrowse link 20 6,869,870 6,910,022 RGD:1624291
RGD:1600115
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
positive regulation of histone deacetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap8 A-kinase anchoring protein 8 JBrowse link 7 14,323,298 14,339,953 RGD:1624291
G Akap8l A-kinase anchoring protein 8 like JBrowse link 7 14,340,168 14,369,835 RGD:1624291
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Ctbp1 C-terminal binding protein 1 JBrowse link 14 82,762,109 82,789,350 RGD:1624291
RGD:1600115
G Ing2 inhibitor of growth family, member 2 JBrowse link 16 47,714,756 47,725,836 RGD:1624291
G Jdp2 Jun dimerization protein 2 JBrowse link 6 109,464,910 109,505,591 RGD:1624291
G Lpin1 lipin 1 JBrowse link 6 41,796,214 41,905,149 RGD:1624291
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 10 48,629,121 48,772,890 RGD:1624291
G Nipbl NIPBL, cohesin loading factor JBrowse link 2 57,508,830 57,676,197 RGD:1624291
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
G Sdr16c5 short chain dehydrogenase/reductase family 16C, member 5 JBrowse link 5 16,904,926 16,930,111 RGD:1624291
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1624291
positive regulation of histone deubiquitination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sart3 spliceosome associated factor 3, U4/U6 recycling protein JBrowse link 12 48,628,198 48,656,096 RGD:1624291
positive regulation of histone H2B ubiquitination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk9 cyclin-dependent kinase 9 JBrowse link 3 11,742,269 11,747,117 RGD:1624291
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component JBrowse link 1 175,839,140 175,869,167 RGD:1624291
G Rnf20 ring finger protein 20 JBrowse link 5 64,892,996 64,920,397 RGD:1624291
G Rnf40 ring finger protein 40 JBrowse link 1 199,037,472 199,052,823 RGD:1624291
positive regulation of histone H3-K14 acetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
G Kat2b lysine acetyltransferase 2B JBrowse link 9 4,440,982 4,492,949 RGD:7364756
G Nap1l2 nucleosome assembly protein 1-like 2 JBrowse link X 73,997,274 73,999,677 RGD:1624291
G Piwil2 piwi-like RNA-mediated gene silencing 2 JBrowse link 15 52,037,693 52,116,277 RGD:1624291
G Wbp2 WW domain binding protein 2 JBrowse link 10 104,629,563 104,637,906 RGD:1600115
RGD:1624291
positive regulation of histone H3-K27 acetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:1624291
RGD:1600115
positive regulation of histone H3-K27 methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eed embryonic ectoderm development JBrowse link 1 154,189,252 154,216,340 RGD:1624291
G Mtf2 metal response element binding transcription factor 2 JBrowse link 14 2,656,776 2,701,027 RGD:1624291
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 71,540,870 71,585,906 RGD:1600115
RGD:1624291
G Phf1 PHD finger protein 1 JBrowse link 20 5,526,926 5,531,940 RGD:1624291
G Phf19 PHD finger protein 19 JBrowse link 3 13,957,136 13,978,283 RGD:1624291
positive regulation of histone H3-K27 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asxl2 ASXL transcriptional regulator 2 JBrowse link 6 27,835,346 27,919,285 RGD:1624291
G Kpna7 karyopherin subunit alpha 7 JBrowse link 12 11,347,631 11,378,810 RGD:1624291
positive regulation of histone H3-K36 methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
positive regulation of histone H3-K36 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brd4 bromodomain containing 4 JBrowse link 7 14,222,101 14,303,055 RGD:1624291
G Nsd3 nuclear receptor binding SET domain protein 3 JBrowse link 16 71,126,276 71,237,118 RGD:1624291
G Prdm9 PR/SET domain 9 JBrowse link 1 57,533,602 57,555,155 RGD:1624291
RGD:1600115
positive regulation of histone H3-K4 methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Auts2 activator of transcription and developmental regulator AUTS2 JBrowse link 12 27,155,362 28,252,752 RGD:1624291
RGD:1600115
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1624291
RGD:1600115
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component JBrowse link 1 175,839,140 175,869,167 RGD:1624291
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:1600115
RGD:1624291
G Dnmt3b DNA methyltransferase 3 beta JBrowse link 3 149,131,541 149,170,061 RGD:1624291
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:1624291
RGD:1600115
G Kmt2a lysine methyltransferase 2A JBrowse link 8 49,110,407 49,185,872 RGD:1624291
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:1624291
G Nelfa negative elongation factor complex member A JBrowse link 14 82,093,837 82,117,913 RGD:9693718
G Nelfe negative elongation factor complex member E JBrowse link 20 4,530,328 4,536,085 RGD:9693718
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
G Rtf1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) JBrowse link 3 111,478,350 111,537,941 RGD:1624291
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
G Snw1 SNW domain containing 1 JBrowse link 6 111,483,698 111,507,782 RGD:1624291
G Wdr5 WD repeat domain 5 JBrowse link 3 6,061,892 6,080,724 RGD:1600115
RGD:1624291
G Wdr61 WD repeat domain 61 JBrowse link 8 59,296,339 59,313,663 RGD:1624291
RGD:1600115
positive regulation of histone H3-K4 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kmt2e lysine methyltransferase 2E JBrowse link 4 8,187,751 8,255,578 RGD:1624291
G Prdm9 PR/SET domain 9 JBrowse link 1 57,533,602 57,555,155 RGD:1600115
RGD:1624291
positive regulation of histone H3-K79 methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component JBrowse link 1 175,839,140 175,869,167 RGD:1624291
G Wdr61 WD repeat domain 61 JBrowse link 8 59,296,339 59,313,663 RGD:1624291
RGD:1600115
positive regulation of histone H3-K9 acetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1624291
RGD:1600115
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
G Kat2b lysine acetyltransferase 2B JBrowse link 9 4,440,982 4,492,949 RGD:7364756
G Nap1l2 nucleosome assembly protein 1-like 2 JBrowse link X 73,997,274 73,999,677 RGD:1624291
G Pih1d1 PIH1 domain containing 1 JBrowse link 1 101,151,240 101,156,806 RGD:1624291
G Piwil2 piwi-like RNA-mediated gene silencing 2 JBrowse link 15 52,037,693 52,116,277 RGD:1624291
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 JBrowse link 20 13,679,955 13,702,821 RGD:1624291
G Sphk2 sphingosine kinase 2 JBrowse link 1 101,692,972 101,700,604 RGD:1624291
positive regulation of histone H3-K9 dimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dmrtc2 DMRT-like family C2 JBrowse link 1 81,734,256 81,741,419 RGD:1624291
G Prdm12 PR/SET domain 12 JBrowse link 3 10,181,104 10,199,185 RGD:1624291
RGD:13792537
positive regulation of histone H3-K9 methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1624291
RGD:1600115
G Gfi1b growth factor independent 1B transcriptional repressor JBrowse link 3 7,190,721 7,203,444 RGD:1624291
G H1f5 H1.5 linker histone, cluster member JBrowse link 17 44,766,313 44,766,981 RGD:1624291
G Jarid2 jumonji and AT-rich interaction domain containing 2 JBrowse link 17 20,183,440 20,365,219 RGD:1624291
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:1624291
G Prdm12 PR/SET domain 12 JBrowse link 3 10,181,104 10,199,185 RGD:1624291
RGD:13792537
G Prdm6 PR/SET domain 6 JBrowse link 18 48,433,747 48,538,834 RGD:13792537
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
RGD:1600115
positive regulation of histone H3-K9 trimethylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dmrtc2 DMRT-like family C2 JBrowse link 1 81,734,256 81,741,419 RGD:1624291
G Lmna lamin A/C JBrowse link 2 187,842,884 187,863,552 RGD:1624291
RGD:1600115
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:1600115
RGD:1624291
G Suv39h1 suppressor of variegation 3-9 homolog 1 JBrowse link X 146,532,002 146,533,538 RGD:1624291
positive regulation of histone H4 acetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
G Kat7 lysine acetyltransferase 7 JBrowse link 10 83,095,067 83,128,342 RGD:1624291
RGD:1600115
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:1624291
G Pih1d1 PIH1 domain containing 1 JBrowse link 1 101,151,240 101,156,806 RGD:1624291
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 JBrowse link 20 13,679,955 13,702,821 RGD:1624291
positive regulation of histone H4-K16 acetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Auts2 activator of transcription and developmental regulator AUTS2 JBrowse link 12 27,155,362 28,252,752 RGD:1624291
RGD:1600115
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1624291
RGD:1600115
positive regulation of histone H4-K20 methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1624291
RGD:1600115
positive regulation of histone methylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chtop chromatin target of PRMT1 JBrowse link 2 189,887,850 189,900,079 RGD:1624291
RGD:1600115
G L3mbtl2 L3MBTL histone methyl-lysine binding protein 2 JBrowse link 7 122,896,860 122,918,025 RGD:1624291
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:1624291
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component JBrowse link 1 85,362,421 85,367,999 RGD:1624291
G Pax7 paired box 7 JBrowse link 5 158,211,001 158,313,510 RGD:1624291
G Paxbp1 PAX3 and PAX7 binding protein 1 JBrowse link 11 31,184,456 31,213,891 RGD:1624291
G Rnf20 ring finger protein 20 JBrowse link 5 64,892,996 64,920,397 RGD:1624291
G Tet1 tet methylcytosine dioxygenase 1 JBrowse link 20 27,359,122 27,438,039 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
positive regulation of histone phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:2316101
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:1578405
RGD:1624291
G Cdk9 cyclin-dependent kinase 9 JBrowse link 3 11,742,269 11,747,117 RGD:1624291
G Daxx death-domain associated protein JBrowse link 20 5,480,103 5,485,962 RGD:9587767
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:1600115
RGD:1624291
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:1624291
G Rps6ka4 ribosomal protein S6 kinase A4 JBrowse link 1 222,087,328 222,098,284 RGD:1624291
G Rps6ka5 ribosomal protein S6 kinase A5 JBrowse link 6 124,557,892 124,735,787 RGD:1624291
G Slk STE20-like kinase JBrowse link 1 267,359,761 267,415,735 RGD:9587767
positive regulation of histone ubiquitination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kdm1a lysine demethylase 1A JBrowse link 5 154,909,003 154,965,171 RGD:1624291
G Kdm2a lysine demethylase 2A JBrowse link 1 219,566,130 219,642,294 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      positive regulation of metabolic process 3792
        positive regulation of cellular metabolic process 3482
          positive regulation of cellular protein metabolic process 1668
            positive regulation of protein modification process 1297
              positive regulation of histone modification 107
                positive regulation of histone acetylation + 33
                positive regulation of histone deacetylation + 21
                positive regulation of histone demethylase activity (H3-K4 specific) 0
                positive regulation of histone deubiquitination 1
                positive regulation of histone methylation + 47
                positive regulation of histone phosphorylation 9
                positive regulation of histone ubiquitination + 6
Path 2
Term Annotations click to browse term
  biological_process 19439
    cellular process 18179
      cellular component organization or biogenesis 6367
        cellular component organization 6145
          organelle organization 3856
            chromosome organization 1198
              chromatin organization 801
                covalent chromatin modification 500
                  histone modification 484
                    regulation of histone modification 172
                      positive regulation of histone modification 107
                        positive regulation of histone acetylation + 33
                        positive regulation of histone deacetylation + 21
                        positive regulation of histone demethylase activity (H3-K4 specific) 0
                        positive regulation of histone deubiquitination 1
                        positive regulation of histone methylation + 47
                        positive regulation of histone phosphorylation 9
                        positive regulation of histone ubiquitination + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.