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ONTOLOGY REPORT - ANNOTATIONS


Term:biomineral tissue development
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Accession:GO:0031214 term browser browse the term
Definition:Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation.
Synonyms:xref: Wikipedia:Biomineralization


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biomineral tissue development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBN ameloblastin IEA UniProt GO_REF:0000043 NCBI chr13:59,899,968...59,912,699
Ensembl chr13:59,899,960...59,912,655
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein IEA UniProt GO_REF:0000043 NCBI chr 7:41,630,092...41,630,976
Ensembl chr 7:41,630,098...41,665,791
JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr38:20,002,984...20,152,930
Ensembl chr38:20,008,057...20,152,275
JBrowse link
G DSPP dentin sialophosphoprotein ISO RGD PMID:20425127 RGD:4110819 NCBI chr32:11,017,440...11,022,780 JBrowse link
G FAM20A FAM20A golgi associated secretory pathway pseudokinase ISO (PMID:25789606) UniProtKB PMID:25789606 NCBI chr 9:15,205,887...15,218,873
Ensembl chr 9:15,207,300...15,230,447
JBrowse link
G FAM20C FAM20C golgi associated secretory pathway kinase ISO (PMID:22582013), (PMID:25789606) UniProtKB PMID:22582013, PMID:25789606 NCBI chr 6:16,448,603...16,497,064
Ensembl chr 6:16,448,588...16,497,752
JBrowse link
G IBSP integrin binding sialoprotein IEA UniProt GO_REF:0000043 NCBI chr32:11,187,188...11,200,860
Ensembl chr32:11,187,160...11,200,846
JBrowse link
G ODAM odontogenic, ameloblast associated IEA UniProt GO_REF:0000043 NCBI chr13:59,588,642...59,597,873
Ensembl chr13:59,588,647...59,597,873
JBrowse link
G SLC20A1 solute carrier family 20 member 1 IEA Ensembl GO_REF:0000107 NCBI chr17:36,863,786...36,879,331
Ensembl chr17:36,863,659...36,909,318
JBrowse link
G TFIP11 tuftelin interacting protein 11 IEA UniProt GO_REF:0000043 NCBI chr26:20,177,896...20,192,466
Ensembl chr26:20,177,904...20,192,469
JBrowse link
bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type IEA Ensembl GO_REF:0000107 NCBI chr 5:32,026,193...32,038,698
Ensembl chr 5:31,882,501...32,038,119
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase IEA Ensembl GO_REF:0000107 NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119
JBrowse link
G ASGR2 asialoglycoprotein receptor 2 ISO RGD PMID:19841953 RGD:2316850 NCBI chr 5:32,112,365...32,123,785
Ensembl chr 5:32,111,984...32,119,003
JBrowse link
G ASPN asporin IEA Ensembl GO_REF:0000107 NCBI chr 1:98,881,610...98,905,641
Ensembl chr 1:98,881,690...98,904,945
JBrowse link
G ATF4 activating transcription factor 4 IEA Ensembl GO_REF:0000107 NCBI chr10:25,528,880...25,531,018
Ensembl chr10:25,528,874...25,530,993
JBrowse link
G AXIN2 axin 2 IEA Ensembl GO_REF:0000107 NCBI chr 9:14,559,476...14,588,950
Ensembl chr 9:14,559,388...14,588,530
JBrowse link
G BMP2 bone morphogenetic protein 2 ISO (MGI:3850932|PMID:19213727)
(MGI:3528531|PMID:15657444), (MGI:3850932|PMID:19213727)
MGI PMID:15657444, PMID:19213727 MGI:3528531, MGI:3850932 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217
JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist IEA Ensembl GO_REF:0000107 NCBI chr11:35,155,568...35,159,085
Ensembl chr11:35,156,430...35,158,942
JBrowse link
G CLEC3B C-type lectin domain family 3 member B IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:43,319,786...43,332,161
Ensembl chr20:43,324,231...43,332,135
JBrowse link
G COL1A2 collagen type I alpha 2 chain IEA Ensembl GO_REF:0000107 NCBI chr14:19,883,731...19,919,527
Ensembl chr14:19,883,868...19,919,527
JBrowse link
G COMP cartilage oligomeric matrix protein IEA Ensembl GO_REF:0000107 NCBI chr20:44,306,813...44,314,575
Ensembl chr20:44,306,859...44,314,625
JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 IEA Ensembl GO_REF:0000107 NCBI chr10:1,825,224...1,830,845
Ensembl chr10:1,826,046...1,829,911
JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 ISO (MGI:5780798|PMID:21308776) MGI PMID:21308776 MGI:5780798 NCBI chr 8:68,961,975...68,970,106
Ensembl chr 8:68,961,744...68,972,761
JBrowse link
G DUOX2 dual oxidase 2 IEA Ensembl GO_REF:0000107 NCBI chr30:11,521,833...11,541,719
Ensembl chr30:11,521,845...11,541,716
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:2179907|PMID:11997520) MGI PMID:11997520 MGI:2179907 NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit IEA Ensembl GO_REF:0000107 NCBI chr 1:110,173,781...110,191,612
Ensembl chr 1:110,173,715...110,190,125
JBrowse link
G FBXL15 F-box and leucine rich repeat protein 15 ISS UniProtKB GO_REF:0000024 NCBI chr28:14,927,740...14,929,867
Ensembl chr28:14,927,532...14,929,863
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO (MGI:3043470|PMID:12756187) MGI PMID:12756187 MGI:3043470 NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 ISO (MGI:4457789|PMID:20582225) BHF-UCL PMID:20582225 MGI:4457789 NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896
JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 2:72,678,858...72,692,417
Ensembl chr 2:72,680,675...72,690,251
JBrowse link
G GLA galactosidase alpha NOT ISO (MGI:3692334|PMID:16697974) MGI PMID:16697974 MGI:3692334 NCBI chr  X:75,311,536...75,320,391
Ensembl chr  X:75,311,536...75,320,249
JBrowse link
G GPC3 glypican 3 IEA Ensembl GO_REF:0000107 NCBI chr  X:104,313,426...104,751,215
Ensembl chr  X:104,313,591...104,751,756
JBrowse link
G GPNMB glycoprotein nmb ISO RGD PMID:11746512 RGD:632991 NCBI chr14:36,919,184...36,947,023
Ensembl chr14:36,919,296...36,946,643
JBrowse link
G IBSP integrin binding sialoprotein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr32:11,187,188...11,200,860
Ensembl chr32:11,187,160...11,200,846
JBrowse link
G ICMT isoprenylcysteine carboxyl methyltransferase ISO (MGI:5500993|PMID:23686339) MGI PMID:23686339 MGI:5500993 NCBI chr 5:60,119,793...60,128,531
Ensembl chr 5:60,123,054...60,149,027
JBrowse link
G KLF10 Kruppel like factor 10 IEA Ensembl GO_REF:0000107 NCBI chr13:4,216,745...4,223,708
Ensembl chr13:4,218,084...4,223,691
JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 IEA Ensembl GO_REF:0000107 NCBI chr21:47,952,019...47,995,530
Ensembl chr21:47,952,890...47,996,288
JBrowse link
G LOX lysyl oxidase IEA Ensembl GO_REF:0000107 NCBI chr11:12,023,645...12,040,015
Ensembl chr11:12,027,250...12,039,819
JBrowse link
G MMP13 matrix metallopeptidase 13 IEA Ensembl GO_REF:0000107 NCBI chr 5:28,793,568...28,864,832
Ensembl chr 5:28,850,522...28,864,121
JBrowse link
G MTSS1 MTSS I-BAR domain containing 1 ISO (MGI:5317250|PMID:21406566) MGI PMID:21406566 MGI:5317250 NCBI chr13:22,633,001...22,794,960
Ensembl chr13:22,635,230...22,794,453
JBrowse link
G PHEX phosphate regulating endopeptidase homolog X-linked IEA Ensembl GO_REF:0000107 NCBI chr  X:17,830,714...18,038,755
Ensembl chr  X:17,829,158...18,035,775
JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic IEA Ensembl GO_REF:0000107 NCBI chr17:33,659,352...33,669,237
Ensembl chr17:33,659,272...33,668,892
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO PMID:18519738 MGI PMID:18519738 RGD:8554572 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903
JBrowse link
G PTH1R parathyroid hormone 1 receptor IEA Ensembl GO_REF:0000107 NCBI chr20:41,905,265...41,924,712
Ensembl chr20:41,905,273...41,925,794
JBrowse link
G PTHLH parathyroid hormone like hormone NOT IEA
ISO
(MGI:2153596|PMID:11606467) InterPro
MGI
PMID:11606467 GO_REF:0000002, MGI:2153596 NCBI chr27:19,781,557...19,795,078
Ensembl chr27:19,781,557...19,795,078
JBrowse link
G PTN pleiotrophin IEA Ensembl GO_REF:0000107 NCBI chr16:11,283,078...11,382,820
Ensembl chr16:11,283,077...11,382,814
JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:23337931 RGD:11537369 NCBI chr 1:95,209,122...95,280,956
Ensembl chr 1:95,088,745...95,280,151
JBrowse link
G RSPO2 R-spondin 2 IEA Ensembl GO_REF:0000107 NCBI chr13:8,610,227...8,755,727
Ensembl chr13:8,611,952...8,754,859
JBrowse link
G SBDS SBDS ribosome maturation factor IEA Ensembl GO_REF:0000107 NCBI chr 6:1,256,087...1,263,482
Ensembl chr 6:1,256,546...1,263,467
JBrowse link
G SBNO2 strawberry notch homolog 2 IEA Ensembl GO_REF:0000107 NCBI chr20:57,592,901...57,640,047
Ensembl chr20:57,267,724...57,640,750
JBrowse link
G SLC24A3 solute carrier family 24 member 3 ISO (MGI:6104227|PMID:28602864) ARUK-UCL PMID:28602864 MGI:6104227 NCBI chr24:3,593,562...4,014,366
Ensembl chr24:3,593,513...3,784,467
JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 IEA Ensembl GO_REF:0000107 NCBI chr 5:81,089,657...81,172,173
Ensembl chr 5:81,142,888...81,172,189
JBrowse link
G TCF7L2 transcription factor 7 like 2 ISO (MGI:3850932|PMID:19213727) MGI PMID:19213727 MGI:3850932 NCBI chr28:23,966,079...24,162,775
Ensembl chr28:23,966,073...24,163,737
JBrowse link
G TMEM38B transmembrane protein 38B IEA Ensembl GO_REF:0000107 NCBI chr11:61,511,756...61,561,987
Ensembl chr11:61,511,750...61,560,556
JBrowse link
G WNT11 Wnt family member 11 IEA Ensembl GO_REF:0000107 NCBI chr21:22,442,496...22,463,040
Ensembl chr21:22,446,051...22,463,173
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 IEA Ensembl GO_REF:0000107 NCBI chr15:2,669,546...2,708,480
Ensembl chr15:2,670,326...2,709,160
JBrowse link
bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO6 anoctamin 6 IEA Ensembl GO_REF:0000107 NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934
JBrowse link
G BMP2 bone morphogenetic protein 2 ISS
IEA
UniProtKB
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217
JBrowse link
G CCDC154 coiled-coil domain containing 154 ISO (MGI:5697796|PMID:20121924) MGI PMID:20121924 MGI:5697796 NCBI chr 6:39,356,234...39,364,053
Ensembl chr 6:39,357,273...39,364,740
JBrowse link
G IFT80 intraflagellar transport 80 ISO (MGI:5807019|PMID:26996322) MGI PMID:26996322 MGI:5807019 NCBI chr34:26,332,456...26,455,428 JBrowse link
G IGF1 insulin like growth factor 1 IEA Ensembl GO_REF:0000107 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794
JBrowse link
G LEP leptin ISO RGD PMID:21353474 RGD:5128507 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395
JBrowse link
G PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:25,385,313...25,392,278
Ensembl chr 9:25,385,396...25,392,242
JBrowse link
G SNX10 sorting nexin 10 ISO (MGI:5688814|PMID:25811986) MGI PMID:25811986 MGI:5688814 NCBI chr14:39,567,701...39,642,475
Ensembl chr14:39,567,471...39,640,872
JBrowse link
cementum mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPL alkaline phosphatase, biomineralization associated ISO RGD PMID:17043865 RGD:2316162 NCBI chr 2:77,559,791...77,614,102
Ensembl chr 2:77,559,791...77,614,820
JBrowse link
G HACD1 3-hydroxyacyl-CoA dehydratase 1 ISO (PMID:25263524) UniProtKB PMID:25263524 NCBI chr 2:19,362,488...19,383,090
Ensembl chr 2:19,362,403...19,383,090
JBrowse link
dentin mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 IEA Ensembl GO_REF:0000107 NCBI chr18:49,784,480...49,794,361
Ensembl chr18:49,784,490...49,794,317
JBrowse link
enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMELX amelogenin X-linked IEA Ensembl GO_REF:0000107 NCBI chr  X:7,822,513...7,828,692
Ensembl chr  X:7,822,859...7,830,351
JBrowse link
G CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 IEA Ensembl GO_REF:0000107 NCBI chr10:45,157,418...45,197,323
Ensembl chr10:45,138,538...45,197,244
JBrowse link
G FAM20A FAM20A golgi associated secretory pathway pseudokinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:15,205,887...15,218,873
Ensembl chr 9:15,207,300...15,230,447
JBrowse link
G FAM20C FAM20C golgi associated secretory pathway kinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:16,448,603...16,497,064
Ensembl chr 6:16,448,588...16,497,752
JBrowse link
G FOXO1 forkhead box O1 ISO RGD PMID:25183529 RGD:10044263 NCBI chr25:603,433...706,961
Ensembl chr25:603,543...702,825
JBrowse link
G ITGB6 integrin subunit beta 6 ISO (MGI:5507902|PMID:23264742) MGI PMID:23264742 MGI:5507902 NCBI chr36:5,833,206...5,962,699
Ensembl chr36:5,834,638...5,962,633
JBrowse link
G MSX2 msh homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:38,002,724...38,007,407
Ensembl chr 4:38,002,428...38,007,407
JBrowse link
G NECTIN1 nectin cell adhesion molecule 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:14,228,197...14,292,825
Ensembl chr 5:14,228,197...14,315,060
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha IEA Ensembl GO_REF:0000107 NCBI chr10:19,934,020...20,006,096
Ensembl chr10:19,934,165...20,006,146
JBrowse link
G STIM1 stromal interaction molecule 1 ISO (PMID:24621671) UniProtKB PMID:24621671 NCBI chr21:26,394,592...26,594,764
Ensembl chr21:26,394,811...26,593,375
JBrowse link
G TBX1 T-box transcription factor 1 ISS UniProt GO_REF:0000024 NCBI chr26:29,529,071...29,533,240
Ensembl chr26:29,528,878...29,532,784
JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 IEA Ensembl GO_REF:0000107 NCBI chr18:49,784,480...49,794,361
Ensembl chr18:49,784,490...49,794,317
JBrowse link
G WDR72 WD repeat domain 72 IEA Ensembl GO_REF:0000107 NCBI chr30:19,120,021...19,340,781
Ensembl chr30:19,122,674...19,326,874
JBrowse link
negative regulation of biomineral tissue development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B9D2 B9 domain containing 2 ISO (PMID:26634652)
(MGI:5921830|PMID:26634652)
BHF-UCL PMID:26634652 MGI:5921830 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G GAS6 growth arrest specific 6 IEA Ensembl GO_REF:0000107 NCBI chr22:60,975,196...61,005,869
Ensembl chr22:60,974,849...61,005,875
JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 ISO (MGI:6158746|PMID:22110751) BHF-UCL PMID:22110751 MGI:6158746 NCBI chr29:27,185,191...27,188,121
Ensembl chr29:27,185,191...27,188,121
JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 ISO (MGI:6158746|PMID:22110751) BHF-UCL PMID:22110751 MGI:6158746 NCBI chr 1:64,630,656...64,646,546 JBrowse link
G NOS3 nitric oxide synthase 3 IEA Ensembl GO_REF:0000107 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277
JBrowse link
G NOTCH1 notch receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chr 7:66,862,614...67,001,538
Ensembl chr 7:66,862,608...67,142,853
JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chr17:7,931,786...8,012,484
Ensembl chr17:7,934,739...8,178,707
JBrowse link
G SOX9 SRY-box transcription factor 9 ISS UniProtKB GO_REF:0000024 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172
JBrowse link
G TGFB1 transforming growth factor beta 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
negative regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHSG alpha 2-HS glycoprotein IEA Ensembl GO_REF:0000107 NCBI chr34:19,221,034...19,228,866
Ensembl chr34:19,221,107...19,228,716
JBrowse link
G BCOR BCL6 corepressor IEA Ensembl GO_REF:0000107 NCBI chr  X:34,621,314...34,735,502
Ensembl chr  X:34,621,886...34,645,766
JBrowse link
G CCR1 chemokine (C-C motif) receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr20:42,421,356...42,427,177
Ensembl chr20:42,421,356...42,426,958
JBrowse link
G ECM1 extracellular matrix protein 1 IEA Ensembl GO_REF:0000107 NCBI chr17:59,696,125...59,701,990
Ensembl chr17:59,696,477...59,701,744
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO (MGI:5607146|PMID:25479107), (MGI:6220772|PMID:30111653), (MGI:6294341|PMID:22510396) UniProt PMID:22510396, PMID:25479107, PMID:30111653 MGI:5607146, MGI:6220772, MGI:6294341 NCBI chr 1:251,985...322,081
Ensembl chr 1:252,103...322,718
JBrowse link
G FGF23 fibroblast growth factor 23 IEA Ensembl GO_REF:0000107 NCBI chr27:40,501,655...40,511,785
Ensembl chr27:40,501,731...40,509,766
JBrowse link
G GATA1 GATA binding protein 1 IEA Ensembl GO_REF:0000107 NCBI chr  X:41,991,321...41,998,319
Ensembl chr  X:41,971,582...41,998,303
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692
JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 ISO (MGI:2178869|PMID:11790802) MGI PMID:11790802 MGI:2178869 NCBI chr18:51,653,783...51,667,793
Ensembl chr18:51,659,098...51,667,433
JBrowse link
G MEPE matrix extracellular phosphoglycoprotein ISO (MGI:5431257|PMID:22766095)
(MGI:2448336|PMID:12421822), (MGI:3851320|PMID:15843468)
MGI PMID:12421822, PMID:15843468, PMID:22766095 MGI:2448336, MGI:3851320, MGI:5431257 NCBI chr32:11,212,531...11,222,805
Ensembl chr32:11,212,531...11,222,805
JBrowse link
G NFE2 nuclear factor, erythroid 2 ISO (MGI:3653541|PMID:15005853) MGI PMID:15005853 MGI:3653541 NCBI chr27:1,003,551...1,010,514
Ensembl chr27:1,003,816...1,010,264
JBrowse link
G PTK2B protein tyrosine kinase 2 beta IEA Ensembl GO_REF:0000107 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133
JBrowse link
G SOX9 SRY-box transcription factor 9 ISO (MGI:2135696|PMID:11371614) MGI PMID:11371614 MGI:2135696 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172
JBrowse link
G SRGN serglycin IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:20,230,713...20,244,952
Ensembl chr 4:20,230,743...20,244,474
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23081848 RGD:10003033 NCBI chr 1:107,261,760...107,304,157
Ensembl chr 1:107,261,756...107,303,346
JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist IEA Ensembl GO_REF:0000107 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418
JBrowse link
G PTH parathyroid hormone ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr21:36,417,062...36,419,967
Ensembl chr21:36,417,058...36,419,967
JBrowse link
G RFLNA refilin A IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:5,501,223...5,509,118
Ensembl chr26:5,502,106...5,505,458
JBrowse link
G RFLNB refilin B IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:45,232,910...45,239,569
Ensembl chr 9:45,232,975...45,239,130
JBrowse link
negative regulation of tooth mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASPN asporin IEA Ensembl GO_REF:0000107 NCBI chr 1:98,881,610...98,905,641
Ensembl chr 1:98,881,690...98,904,945
JBrowse link
G BCOR BCL6 corepressor IEA Ensembl GO_REF:0000107 NCBI chr  X:34,621,314...34,735,502
Ensembl chr  X:34,621,886...34,645,766
JBrowse link
otolith mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 ISO (MGI:1275896|PMID:9668038) MGI PMID:9668038 MGI:1275896 NCBI chr20:7,665,468...8,037,407
Ensembl chr20:7,749,807...8,034,474
JBrowse link
G OC90 otoconin 90 ISO (MGI:5896790|PMID:21655225), (MGI:6189500|PMID:24748133) UniProt PMID:21655225, PMID:24748133 MGI:5896790, MGI:6189500 NCBI chr13:28,680,910...28,700,816 JBrowse link
G OTOL1 otolin 1 IEA Ensembl GO_REF:0000107 NCBI chr34:27,405,456...27,454,726
Ensembl chr34:27,413,694...27,455,023
JBrowse link
positive regulation of biomineral tissue development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMTN amelotin ISO (PMID:25407797) UniProtKB PMID:25407797 NCBI chr13:59,855,278...59,867,133
Ensembl chr13:59,852,490...59,867,516
JBrowse link
G ATF4 activating transcription factor 4 IEA Ensembl GO_REF:0000107 NCBI chr10:25,528,880...25,531,018
Ensembl chr10:25,528,874...25,530,993
JBrowse link
G CEBPB CCAAT enhancer binding protein beta IEA Ensembl GO_REF:0000107 NCBI chr24:36,661,294...36,663,162
Ensembl chr24:36,661,616...36,662,656
JBrowse link
G FBXO5 F-box protein 5 IEA Ensembl GO_REF:0000107 NCBI chr 1:43,138,338...43,149,546
Ensembl chr 1:43,138,889...43,149,297
JBrowse link
G ODAPH odontogenesis associated phosphoprotein ISO (PMID:22901946) UniProtKB PMID:22901946 NCBI chr32:133,974...141,303 JBrowse link
positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 IEA Ensembl GO_REF:0000107 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652
JBrowse link
G ACVR2A activin A receptor type 2A ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr19:49,642,429...49,726,720
Ensembl chr19:49,641,219...49,723,420
JBrowse link
G ACVR2B activin A receptor type 2B IEA Ensembl GO_REF:0000107 NCBI chr23:8,211,555...8,225,596
Ensembl chr23:8,192,483...8,218,894
JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 ISO (MGI:6211994|PMID:22419726) UniProt PMID:22419726 MGI:6211994 NCBI chr 3:17,866,459...18,351,532
Ensembl chr 3:17,866,808...18,351,532
JBrowse link
G ADRB2 adrenoceptor beta 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase IEA Ensembl GO_REF:0000107 NCBI chr28:2,170,920...2,218,765
Ensembl chr28:2,170,920...2,219,609
JBrowse link
G ANO6 anoctamin 6 IEA InterPro
Ensembl
GO_REF:0000002, GO_REF:0000107 NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 IEA Ensembl GO_REF:0000107 NCBI chr15:30,547,009...30,674,094
Ensembl chr15:30,547,015...30,616,429
JBrowse link
G ATRAID all-trans retinoic acid induced differentiation factor IEA Ensembl GO_REF:0000107 NCBI chr17:21,193,685...21,198,897
Ensembl chr17:21,193,909...21,198,718
JBrowse link
G B9D2 B9 domain containing 2 ISS AgBase GO_REF:0000024 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G BMP2 bone morphogenetic protein 2 ISS
IEA
UniProtKB
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217
JBrowse link
G BMP4 bone morphogenetic protein 4 IEA Ensembl GO_REF:0000107 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557
JBrowse link
G BMP6 bone morphogenetic protein 6 IEA Ensembl GO_REF:0000107 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845
JBrowse link
G BMP7 bone morphogenetic protein 7 IEA Ensembl GO_REF:0000107 NCBI chr24:42,203,183...42,294,105
Ensembl chr24:42,204,823...42,294,653
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A IEA Ensembl GO_REF:0000107 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923
JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B IEA Ensembl GO_REF:0000107 NCBI chr32:17,761,555...17,978,056
Ensembl chr32:17,870,904...18,016,444
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 IEA Ensembl GO_REF:0000107 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024
JBrowse link
G CCN1 cellular communication network factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:62,443,285...62,446,246
Ensembl chr 6:62,443,675...62,445,994
JBrowse link
G CD276 CD276 molecule ISO (MGI:3052626|PMID:15317945) MGI PMID:15317945 MGI:3052626 NCBI chr30:36,975,085...36,990,012
Ensembl chr30:36,975,085...36,988,924
JBrowse link
G FAM20C FAM20C golgi associated secretory pathway kinase IEA Ensembl GO_REF:0000107 NCBI chr 6:16,448,603...16,497,064
Ensembl chr 6:16,448,588...16,497,752
JBrowse link
G FBN2 fibrillin 2 IEA Ensembl GO_REF:0000107 NCBI chr11:17,311,238...17,551,536
Ensembl chr11:17,311,226...17,551,536
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 ISO (MGI:4437389|PMID:20053668) MGI PMID:20053668 MGI:4437389 NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896
JBrowse link
G FZD9 frizzled class receptor 9 IEA Ensembl GO_REF:0000107 NCBI chr 6:6,782,394...6,784,565
Ensembl chr 6:6,782,774...6,784,558
JBrowse link
G GPM6B glycoprotein M6B IEA Ensembl GO_REF:0000107 NCBI chr  X:10,214,889...10,375,151
Ensembl chr  X:10,214,933...10,374,837
JBrowse link
G ISG15 ISG15 ubiquitin like modifier IEA Ensembl GO_REF:0000107 NCBI chr 5:56,230,879...56,237,354
Ensembl chr 5:56,236,318...56,404,695
JBrowse link
G KL klotho ISO (PMID:12110410) UniProtKB PMID:12110410 NCBI chr25:7,154,359...7,201,744
Ensembl chr25:7,156,620...7,199,558
JBrowse link
G MEF2C myocyte enhancer factor 2C ISS
IEA
UniProtKB
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 3:19,778,997...19,948,203
Ensembl chr 3:19,779,007...19,943,852
JBrowse link
G MIA3 MIA SH3 domain ER export factor 3 ISO (MGI:5008683|PMID:21606205) MGI PMID:21606205 MGI:5008683 NCBI chr38:16,880,411...16,936,368
Ensembl chr38:16,879,740...16,935,844
JBrowse link
G NELL1 neural EGFL like 1 ISO (PMID:21723284) UniProtKB PMID:21723284 NCBI chr21:42,654,925...43,468,806
Ensembl chr21:42,656,339...43,468,806
JBrowse link
G OSR1 odd-skipped related transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr17:14,508,543...14,515,657
Ensembl chr17:14,509,333...14,589,228
JBrowse link
G OSR2 odd-skipped related transciption factor 2 IEA Ensembl GO_REF:0000107 NCBI chr13:1,019,167...1,031,622
Ensembl chr13:1,023,879...1,031,225
JBrowse link
G P2RX7 purinergic receptor P2X 7 ISO (MGI:2667237|PMID:12677010), (MGI:3797675|PMID:18519738) MGI PMID:12677010, PMID:18519738 MGI:2667237, MGI:3797675 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740
JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic IEA Ensembl GO_REF:0000107 NCBI chr17:33,659,352...33,669,237
Ensembl chr17:33,659,272...33,668,892
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chr 7:19,804,412...19,955,215
Ensembl chr 7:19,832,664...19,966,936
JBrowse link
G PTH parathyroid hormone IEA Ensembl GO_REF:0000107 NCBI chr21:36,417,062...36,419,967
Ensembl chr21:36,417,058...36,419,967
JBrowse link
G PTN pleiotrophin IEA Ensembl GO_REF:0000107 NCBI chr16:11,283,078...11,382,820
Ensembl chr16:11,283,077...11,382,814
JBrowse link
G SLC8A1 solute carrier family 8 member A1 IEA Ensembl GO_REF:0000107 NCBI chr17:32,004,207...32,381,399
Ensembl chr17:32,005,245...32,307,700
JBrowse link
G SMAD3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337
JBrowse link
G TFAP2A transcription factor AP-2 alpha IEA Ensembl GO_REF:0000107 NCBI chr35:10,157,043...10,180,484
Ensembl chr35:10,157,882...10,180,270
JBrowse link
G TGFB1 transforming growth factor beta 1 ISS AgBase GO_REF:0000024 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G TGFB3 transforming growth factor beta 3 ISS AgBase GO_REF:0000024 NCBI chr 8:48,920,874...48,946,037
Ensembl chr 8:48,923,423...48,945,816
JBrowse link
G TMEM119 transmembrane protein 119 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:18,275,719...18,282,905
Ensembl chr26:18,260,923...18,282,409
JBrowse link
G WNT10B Wnt family member 10B IEA Ensembl GO_REF:0000107 NCBI chr27:5,599,905...5,605,506
Ensembl chr27:5,601,089...5,605,501
JBrowse link
G WNT4 Wnt family member 4 IEA Ensembl GO_REF:0000107 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111
JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 IEA Ensembl GO_REF:0000107 NCBI chr18:50,787,353...50,801,036
Ensembl chr18:50,787,353...50,801,197
JBrowse link
G ASXL2 ASXL transcriptional regulator 2 ISO (MGI:5514358|PMID:21490954) MGI PMID:21490954 MGI:5514358 NCBI chr17:19,914,026...20,065,141
Ensembl chr17:19,895,568...20,044,691
JBrowse link
positive regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMTN amelotin IEA Ensembl GO_REF:0000107 NCBI chr13:59,855,278...59,867,133
Ensembl chr13:59,852,490...59,867,516
JBrowse link
G DSPP dentin sialophosphoprotein ISO (MGI:3603472|PMID:16014627) MGI PMID:16014627 MGI:3603472 NCBI chr32:11,017,440...11,022,780 JBrowse link
G ENAM enamelin IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:59,934,299...59,948,279
Ensembl chr13:59,934,299...59,947,949
JBrowse link
G ODAPH odontogenesis associated phosphoprotein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr32:133,974...141,303 JBrowse link
positive regulation of tooth mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TFAP2A transcription factor AP-2 alpha IEA Ensembl GO_REF:0000107 NCBI chr35:10,157,043...10,180,484
Ensembl chr35:10,157,882...10,180,270
JBrowse link
G WNT6 Wnt family member 6 IEA Ensembl GO_REF:0000107 NCBI chr37:25,452,875...25,457,437
Ensembl chr37:25,453,905...25,456,654
JBrowse link
regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKH ANKH inorganic pyrophosphate transport regulator IEA Ensembl GO_REF:0000107 NCBI chr 4:88,149,250...88,263,926
Ensembl chr 4:88,149,257...88,272,464
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein IEA InterPro GO_REF:0000002 NCBI chr 7:41,630,092...41,630,976
Ensembl chr 7:41,630,098...41,665,791
JBrowse link
G BMP2K BMP2 inducible kinase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr32:3,178,554...3,293,397
Ensembl chr32:3,178,460...3,288,926
JBrowse link
G COMP cartilage oligomeric matrix protein IEA Ensembl GO_REF:0000107 NCBI chr20:44,306,813...44,314,575
Ensembl chr20:44,306,859...44,314,625
JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 IEA Ensembl GO_REF:0000107 NCBI chr10:1,825,224...1,830,845
Ensembl chr10:1,826,046...1,829,911
JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr38:20,002,984...20,152,930
Ensembl chr38:20,008,057...20,152,275
JBrowse link
G ECM1 extracellular matrix protein 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:59,696,125...59,701,990
Ensembl chr17:59,696,477...59,701,744
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:251,985...322,081
Ensembl chr 1:252,103...322,718
JBrowse link
G FGF23 fibroblast growth factor 23 ISO (MGI:3510566|PMID:15579309) MGI PMID:15579309 MGI:3510566 NCBI chr27:40,501,655...40,511,785
Ensembl chr27:40,501,731...40,509,766
JBrowse link
G GJA1 gap junction protein alpha 1 ISO (MGI:5317265|PMID:21346198) MGI PMID:21346198 MGI:5317265 NCBI chr 1:60,941,772...60,944,694
Ensembl chr 1:60,929,097...60,942,936
JBrowse link
G MATN1 matrilin 1 ISO (MGI:3655339|PMID:16877353) MGI PMID:16877353 MGI:3655339 NCBI chr 2:70,225,642...70,234,972 JBrowse link
G MGP matrix Gla protein IEA InterPro GO_REF:0000002 NCBI chr27:31,735,301...31,738,673
Ensembl chr27:31,734,660...31,738,673
JBrowse link
G NBR1 NBR1 autophagy cargo receptor IEA Ensembl GO_REF:0000107 NCBI chr 9:19,926,885...19,959,552
Ensembl chr 9:19,915,973...19,958,789
JBrowse link
G OMD osteomodulin IEA InterPro GO_REF:0000002 NCBI chr 1:98,923,507...98,933,751
Ensembl chr 1:98,929,274...98,931,219
JBrowse link
G PTK2B protein tyrosine kinase 2 beta IEA InterPro GO_REF:0000002 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133
JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:48,897,320...48,902,206
Ensembl chr 6:48,897,449...48,900,037
JBrowse link
G SGMS2 sphingomyelin synthase 2 IEA Ensembl GO_REF:0000107 NCBI chr32:28,277,195...28,407,761
Ensembl chr32:28,354,116...28,403,734
JBrowse link
G SUV39H1 suppressor of variegation 3-9 homolog 1 ISO (MGI:5913114|PMID:23695662) MGI PMID:23695662 MGI:5913114 NCBI chr  X:41,894,623...41,907,854
Ensembl chr  X:41,893,045...41,906,403
JBrowse link
G TMEM106A transmembrane protein 106A IEA Ensembl GO_REF:0000107 NCBI chr 9:19,917,591...19,926,578
Ensembl chr 9:19,915,973...19,958,789
JBrowse link
G TXLNG taxilin gamma IEA Ensembl GO_REF:0000107 NCBI chr  X:12,924,612...12,980,926
Ensembl chr  X:12,924,672...12,978,346
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 IEA Ensembl GO_REF:0000107 NCBI chr15:2,669,546...2,708,480
Ensembl chr15:2,670,326...2,709,160
JBrowse link
regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DICER1 dicer 1, ribonuclease III ISO (MGI:4453947|PMID:20102707) MGI PMID:20102707 MGI:4453947 NCBI chr 8:63,970,245...64,029,438
Ensembl chr 8:63,972,027...64,019,879
JBrowse link
G DMP1 dentin matrix acidic phosphoprotein 1 IEA Ensembl GO_REF:0000107 NCBI chr32:11,022,900...11,053,900
Ensembl chr32:11,045,508...11,053,252
JBrowse link
tooth mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMELX amelogenin X-linked ISO (PMID:1483698)
(MGI:2149207|PMID:11406633)
BHF-UCL PMID:1483698, PMID:11406633 MGI:2149207 NCBI chr  X:7,822,513...7,828,692
Ensembl chr  X:7,822,859...7,830,351
JBrowse link
G COL1A1 collagen type I alpha 1 chain IEA Ensembl GO_REF:0000107 NCBI chr 9:26,183,852...26,199,927
Ensembl chr 9:26,183,852...26,199,927
JBrowse link
G TSPEAR thrombospondin type laminin G domain and EAR repeats IEA Ensembl GO_REF:0000107 NCBI chr31:38,273,306...38,340,525
Ensembl chr31:38,272,592...38,337,373
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16190
    biomineralization 167
      biomineral tissue development 165
        bone mineralization + 126
        chitin-based cuticle sclerotization by biomineralization 0
        negative regulation of biomineral tissue development + 29
        otolith mineralization + 3
        positive regulation of biomineral tissue development + 54
        regulation of biomineral tissue development + 99
        shell calcification + 0
        tooth mineralization + 27
Path 2
Term Annotations click to browse term
  biological_process 16190
    developmental process 6310
      anatomical structure development 5858
        multicellular organism development 5351
          system development 4984
            animal organ development 3821
              biomineral tissue development 165
                bone mineralization + 126
                chitin-based cuticle sclerotization by biomineralization 0
                negative regulation of biomineral tissue development + 29
                otolith mineralization + 3
                positive regulation of biomineral tissue development + 54
                regulation of biomineral tissue development + 99
                shell calcification + 0
                tooth mineralization + 27
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.