Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:biomineral tissue development
go back to main search page
Accession:GO:0031214 term browser browse the term
Definition:Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation.
Synonyms:xref: Wikipedia:Biomineralization


show annotations for term's descendants           Sort by:
 
biomineral tissue development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO (MGI:5318020|PMID:19900459) UniProt PMID:19900459 MGI:5318020 NCBI chrNW_004936831:799,948...946,139 JBrowse link
G Dspp dentin sialophosphoprotein ISO RGD PMID:20425127 RGD:4110819 NCBI chrNW_004936905:458,062...463,359 JBrowse link
G Fam20a FAM20A golgi associated secretory pathway pseudokinase ISO (PMID:25789606) UniProtKB PMID:25789606 NCBI chrNW_004936541:7,867,856...7,916,145 JBrowse link
G Fam20c FAM20C golgi associated secretory pathway kinase ISO (PMID:22582013), (PMID:25789606) UniProtKB PMID:22582013, PMID:25789606 NCBI chrNW_004936754:596,878...649,585 JBrowse link
G Slc20a1 solute carrier family 20 member 1 ISO (MGI:5812283|PMID:27812542) MGI PMID:27812542 MGI:5812283 NCBI chrNW_004936783:1,117,835...1,130,739 JBrowse link
bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase ISO (MGI:2686849|PMID:14716014) MGI PMID:14716014 MGI:2686849 NCBI chrNW_004936677:3,232,183...3,241,307 JBrowse link
G Asgr2 asialoglycoprotein receptor 2 ISO RGD PMID:19841953 RGD:2316850 NCBI chrNW_004936595:416,013...423,872 JBrowse link
G Aspn asporin ISO (PMID:19589127) UniProtKB PMID:19589127 NCBI chrNW_004936487:2,080,014...2,104,534 JBrowse link
G Atf4 activating transcription factor 4 ISO (MGI:3040115|PMID:15109498) UniProt PMID:15109498 MGI:3040115 NCBI chrNW_004936492:2,114,478...2,115,969 JBrowse link
G Axin2 axin 2 ISO (MGI:4818263|PMID:19623616) MGI PMID:19623616 MGI:4818263 NCBI chrNW_004936541:7,155,963...7,242,466 JBrowse link
G Bmp2 bone morphogenetic protein 2 ISO (MGI:3850932|PMID:19213727)
(MGI:3528531|PMID:15657444), (MGI:3850932|PMID:19213727)
MGI PMID:15657444, PMID:19213727 MGI:3528531, MGI:3850932 NCBI chrNW_004936485:12,428,765...12,439,570 JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist ISO (PMID:19113921) BHF-UCL PMID:19113921 NCBI chrNW_004936539:8,321,432...8,323,909 JBrowse link
G Clec3b C-type lectin domain family 3 member B ISO (PMID:7589422)
(PMID:7798325)
UniProtKB PMID:7589422, PMID:7798325 NCBI chrNW_004936695:731,184...738,752 JBrowse link
G Col1a2 collagen type I alpha 2 chain ISO (MGI:5468210|PMID:22910579) MGI PMID:22910579 MGI:5468210 NCBI chrNW_004936585:5,650,322...5,686,393 JBrowse link
G Comp cartilage oligomeric matrix protein ISO (MGI:6100855|PMID:27151399) MGI PMID:27151399 MGI:6100855 NCBI chrNW_004936596:2,544,389...2,551,155 JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 ISO (MGI:5780798|PMID:21308776) MGI PMID:21308776 MGI:5780798 NCBI chrNW_004936604:4,504,519...4,511,897 JBrowse link
G Duox2 dual oxidase 2 ISO (MGI:3712355|PMID:17440044) MGI PMID:17440044 MGI:3712355 NCBI chrNW_004936471:7,812,163...7,831,258 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:2179907|PMID:11997520) MGI PMID:11997520 MGI:2179907 NCBI chrNW_004936712:413,602...454,443 JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit ISO (MGI:3692802|PMID:17020410) MGI PMID:17020410 MGI:3692802 NCBI chrNW_004936706:1,816,561...1,829,638 JBrowse link
G Fbxl15 F-box and leucine rich repeat protein 15 ISO PMID:21572392 UniProt PMID:21572392 RGD:8554771 NCBI chrNW_004936600:3,445,840...3,450,369 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO (MGI:3043470|PMID:12756187) MGI PMID:12756187 MGI:3043470 NCBI chrNW_004936486:10,506,680...10,606,272 JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO (MGI:4457789|PMID:20582225) BHF-UCL PMID:20582225 MGI:4457789 NCBI chrNW_004936477:21,591,772...21,606,289 JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase ISO (MGI:3663851|PMID:16964445) MGI PMID:16964445 MGI:3663851 NCBI chrNW_004936474:11,897,998...11,919,153 JBrowse link
G Gla galactosidase alpha NOT ISO (MGI:3692334|PMID:16697974) MGI PMID:16697974 MGI:3692334 NCBI chrNW_004936813:474,938...484,753 JBrowse link
G Gpc3 glypican 3 ISO (MGI:3612305|PMID:15936336) MGI PMID:15936336 MGI:3612305 NCBI chrNW_004936691:1,060,013...1,459,736 JBrowse link
G Gpnmb glycoprotein nmb ISO RGD PMID:11746512 RGD:632991 NCBI chrNW_004936478:397,200...425,663 JBrowse link
G Ibsp integrin binding sialoprotein ISO (MGI:5614132|PMID:25464126) MGI PMID:25464126 MGI:5614132 NCBI chrNW_004936905:316,459...323,446 JBrowse link
G Icmt isoprenylcysteine carboxyl methyltransferase ISO (MGI:5500993|PMID:23686339) MGI PMID:23686339 MGI:5500993 NCBI chrNW_004936623:1,079,474...1,087,728 JBrowse link
G Ifitm5 interferon induced transmembrane protein 5 ISO (PMID:24519609)
(MGI:4359156|PMID:18442316), (MGI:5607401|PMID:20838829)
UniProtKB
MGI
PMID:18442316, PMID:20838829, PMID:24519609 MGI:4359156, MGI:5607401 NCBI chrNW_004936888:160,734...161,960 JBrowse link
G Klf10 Kruppel like factor 10 ISO (MGI:3528531|PMID:15657444) MGI PMID:15657444 MGI:3528531 NCBI chrNW_004936470:40,980,487...40,986,880 JBrowse link
G Lgr4 leucine rich repeat containing G protein-coupled receptor 4 ISO (MGI:4360132|PMID:19605502) UniProt PMID:19605502 MGI:4360132 NCBI chrNW_004936540:5,752,319...5,846,074 JBrowse link
G LOC101978323 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial ISO (PMID:17023519) BHF-UCL PMID:17023519 NCBI chrNW_004936646:1,899,686...1,904,104 JBrowse link
G Lox lysyl oxidase ISO (MGI:5603515|PMID:19458888) MGI PMID:19458888 MGI:5603515 NCBI chrNW_004936575:2,526,067...2,533,996 JBrowse link
G Mmp13 matrix metallopeptidase 13 ISO (MGI:3513736|PMID:15563592)
(MGI:3771509|PMID:17987127)
MGI
UniProt
PMID:15563592, PMID:17987127 MGI:3513736, MGI:3771509 NCBI chrNW_004936551:5,040,084...5,050,384 JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 ISO (MGI:5317250|PMID:21406566) MGI PMID:21406566 MGI:5317250 NCBI chrNW_004936470:22,963,498...23,117,923 JBrowse link
G Phex phosphate regulating endopeptidase homolog X-linked ISO (MGI:3851320|PMID:15843468) MGI PMID:15843468 MGI:3851320 NCBI chrNW_004936624:2,124,479...2,312,847 JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic ISO (MGI:5013998|PMID:21553379) MGI PMID:21553379 MGI:5013998 NCBI chrNW_004936508:9,550,201...9,559,493 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO PMID:18519738 MGI PMID:18519738 RGD:8554572 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Pth1r parathyroid hormone 1 receptor ISO (MGI:2153596|PMID:11606467), (MGI:3624906|PMID:9832460) MGI PMID:9832460, PMID:11606467 MGI:2153596, MGI:3624906 NCBI chrNW_004936596:674,088...693,191 JBrowse link
G Pthlh parathyroid hormone like hormone NOT ISO (MGI:2153596|PMID:11606467) MGI PMID:11606467 MGI:2153596 NCBI chrNW_004936760:197,525...209,212 JBrowse link
G Ptn pleiotrophin ISO (MGI:2429445|PMID:12413943) MGI PMID:12413943 MGI:2429445 NCBI chrNW_004936592:1,706,979...1,806,345 JBrowse link
G Ror2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:23337931 RGD:11537369 NCBI chrNW_004936796:630,307...675,157 JBrowse link
G Rspo2 R-spondin 2 ISO (MGI:3850932|PMID:19213727) MGI PMID:19213727 MGI:3850932 NCBI chrNW_004936470:36,680,716...36,815,347 JBrowse link
G Sbds SBDS ribosome maturation factor ISO (PMID:17920346) UniProtKB PMID:17920346 NCBI chrNW_004936543:7,324,748...7,329,774 JBrowse link
G Sbno2 strawberry notch homolog 2 ISO (MGI:5522615|PMID:23980096) MGI PMID:23980096 MGI:5522615 NCBI chrNW_004936588:509,244...556,424 JBrowse link
G Slc24a3 solute carrier family 24 member 3 ISO (MGI:6104227|PMID:28602864) ARUK-UCL PMID:28602864 MGI:6104227 NCBI chrNW_004936485:637,715...1,085,860 JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 ISO (MGI:5293259|PMID:21788370)
(MGI:5584216|PMID:24585429)
MGI PMID:21788370, PMID:24585429 MGI:5293259, MGI:5584216 NCBI chrNW_004936475:18,667,563...18,755,132 JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO (MGI:3850932|PMID:19213727) MGI PMID:19213727 MGI:3850932 NCBI chrNW_004936486:3,473,877...3,660,565 JBrowse link
G Tmem38b transmembrane protein 38B ISO (MGI:6141091|PMID:27188440) MGI PMID:27188440 MGI:6141091 NCBI chrNW_004936559:6,501,890...6,553,446 JBrowse link
G Wnt11 Wnt family member 11 ISO (MGI:3850932|PMID:19213727) MGI PMID:19213727 MGI:3850932 NCBI chrNW_004936498:4,909,041...4,927,482 JBrowse link
G Zmpste24 zinc metallopeptidase STE24 ISO (MGI:5500993|PMID:23686339) MGI PMID:23686339 MGI:5500993 NCBI chrNW_004936474:22,035,059...22,077,846 JBrowse link
bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano6 anoctamin 6 ISO (MGI:5486117|PMID:22936354) MGI PMID:22936354 MGI:5486117 NCBI chrNW_004936512:3,649,103...3,736,274 JBrowse link
G Bmp2 bone morphogenetic protein 2 ISO (PMID:16433617) BHF-UCL PMID:16433617 NCBI chrNW_004936485:12,428,765...12,439,570 JBrowse link
G Ccdc154 coiled-coil domain containing 154 ISO (MGI:5697796|PMID:20121924) MGI PMID:20121924 MGI:5697796 NCBI chrNW_004936694:2,468,281...2,475,901 JBrowse link
G Ift80 intraflagellar transport 80 ISO (MGI:5807019|PMID:26996322) MGI PMID:26996322 MGI:5807019 NCBI chrNW_004936708:238,302...362,537 JBrowse link
G Igf1 insulin like growth factor 1 ISO (PMID:16433617) BHF-UCL PMID:16433617 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Lep leptin ISO RGD PMID:21353474 RGD:5128507 NCBI chrNW_004936479:15,394,966...15,411,334 JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 ISO (MGI:5008224|PMID:21272676) MGI PMID:21272676 MGI:5008224 NCBI chrNW_004936490:12,272,807...12,280,360 JBrowse link
G Snx10 sorting nexin 10 ISO (MGI:5688814|PMID:25811986) MGI PMID:25811986 MGI:5688814 NCBI chrNW_004936478:3,048,801...3,113,610 JBrowse link
cementum mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated ISO RGD PMID:17043865 RGD:2316162 NCBI chrNW_004936474:7,209,196...7,229,899 JBrowse link
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 ISO (PMID:25263524) UniProtKB PMID:25263524 NCBI chrNW_004936520:9,716,178...9,725,949 JBrowse link
dentin mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tcirg1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 ISO (MGI:5469811|PMID:23174213) MGI PMID:23174213 MGI:5469811 NCBI chrNW_004936599:2,070,211...2,079,169 JBrowse link
enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amelx amelogenin X-linked ISO (PMID:21653221)
(PMID:1916828)
CAFA
BHF-UCL
PMID:1916828, PMID:21653221 NCBI chrNW_004936470:1,169,906...1,174,166 JBrowse link
G Cnnm4 cyclin and CBS domain divalent metal cation transport mediator 4 ISO (MGI:5559016|PMID:24339795) MGI PMID:24339795 MGI:5559016 NCBI chrNW_004936744:715,523...754,148 JBrowse link
G Fam20a FAM20A golgi associated secretory pathway pseudokinase ISO (PMID:21549343), (PMID:21990045), (PMID:23468644)
(MGI:5432245|PMID:22732358)
UniProtKB
MGI
PMID:21549343, PMID:21990045, PMID:22732358, PMID:23468644 MGI:5432245 NCBI chrNW_004936541:7,867,856...7,916,145 JBrowse link
G Fam20c FAM20C golgi associated secretory pathway kinase ISO (MGI:5432245|PMID:22732358) MGI PMID:22732358 MGI:5432245 NCBI chrNW_004936754:596,878...649,585 JBrowse link
G Foxo1 forkhead box O1 ISO RGD PMID:25183529 RGD:10044263 NCBI chrNW_004936565:5,210,014...5,299,213 JBrowse link
G Itgb6 integrin subunit beta 6 ISO (MGI:5507902|PMID:23264742) MGI PMID:23264742 MGI:5507902 NCBI chrNW_004936469:18,581,855...18,650,109 JBrowse link
G Msx2 msh homeobox 2 ISO (MGI:1355063|PMID:10742104) MGI PMID:10742104 MGI:1355063 NCBI chrNW_004936609:1,216,436...1,221,528 JBrowse link
G Nectin1 nectin cell adhesion molecule 1 ISO (MGI:3814115|PMID:18703497) MGI PMID:18703497 MGI:3814115 NCBI chrNW_004936542:4,501,081...4,602,338 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO (MGI:3843118|PMID:19320717) MGI PMID:19320717 MGI:3843118 NCBI chrNW_004936629:3,672,445...3,725,645 JBrowse link
G Stim1 stromal interaction molecule 1 ISO (PMID:24621671) UniProtKB PMID:24621671 NCBI chrNW_004936498:849,775...1,063,552 JBrowse link
G Tbx1 T-box transcription factor 1 ISO (MGI:3848106|PMID:19233155) MGI PMID:19233155 MGI:3848106 NCBI chrNW_004936619:3,662,567...3,670,470 JBrowse link
G Tcirg1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 ISO (MGI:5469811|PMID:23174213) MGI PMID:23174213 MGI:5469811 NCBI chrNW_004936599:2,070,211...2,079,169 JBrowse link
G Wdr72 WD repeat domain 72 ISO (MGI:5605934|PMID:25008349)
(MGI:5906533|PMID:26247047)
MGI PMID:25008349, PMID:26247047 MGI:5605934, MGI:5906533 NCBI chrNW_004936471:15,233,828...15,416,415 JBrowse link
negative regulation of biomineral tissue development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gas6 growth arrest specific 6 ISO (PMID:20048160) UniProtKB PMID:20048160 NCBI chrNW_004936472:27,116...57,158 JBrowse link
G Hey1 hes related family bHLH transcription factor with YRPW motif 1 ISO (MGI:6158746|PMID:22110751) BHF-UCL PMID:22110751 MGI:6158746 NCBI chrNW_004936871:666,961...670,910 JBrowse link
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 ISO (MGI:6158746|PMID:22110751) BHF-UCL PMID:22110751 MGI:6158746 NCBI chrNW_004936639:3,705,225...3,714,696 JBrowse link
G Nos3 nitric oxide synthase 3 ISO (MGI:6158885|PMID:23583836) BHF-UCL PMID:23583836 MGI:6158885 NCBI chrNW_004936527:6,427,147...6,445,770 JBrowse link
G Notch1 notch receptor 1 ISO (MGI:6158885|PMID:23583836)
(MGI:6158728|PMID:26491108)
BHF-UCL PMID:23583836, PMID:26491108 MGI:6158728, MGI:6158885 NCBI chrNW_004936669:1,292,016...1,334,061 JBrowse link
G Rock1 Rho associated coiled-coil containing protein kinase 1 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chrNW_004936550:730,462...874,601 JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chrNW_004936532:7,142,580...7,284,722 JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (PMID:22110751)
(MGI:4947506|PMID:20056916)
BHF-UCL
UniProt
PMID:20056916, PMID:22110751 MGI:4947506 NCBI chrNW_004936655:1,849,044...1,852,648 JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO (PMID:26634652)
(MGI:5921830|PMID:26634652)
BHF-UCL PMID:26634652 MGI:5921830 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
negative regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahsg alpha 2-HS glycoprotein ISO (MGI:3687916|PMID:12556469) RGD
UniProt
PMID:8702833, PMID:12556469 MGI:3687916, RGD:1626074 NCBI chrNW_004936578:3,332,934...3,339,903 JBrowse link
G Bcor BCL6 corepressor ISO (PMID:19578371) UniProtKB PMID:19578371 NCBI chrNW_004936502:6,764,043...6,812,194 JBrowse link
G Ecm1 extracellular matrix protein 1 ISO (PMID:11165938) UniProtKB PMID:11165938 NCBI chrNW_004936580:750,423...756,765 JBrowse link
G Fgf23 fibroblast growth factor 23 ISO (PMID:18282132) UniProtKB PMID:18282132 NCBI chrNW_004936606:4,555,034...4,561,961 JBrowse link
G Gata1 GATA binding protein 1 ISO (MGI:3653541|PMID:15005853) MGI PMID:15005853 MGI:3653541 NCBI chrNW_004936721:742,862...750,843 JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chrNW_004936673:1,394,743...1,399,726 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO (MGI:3777866|PMID:17181398) MGI PMID:17181398 MGI:3777866 NCBI chrNW_004936495:5,770,988...5,816,157 JBrowse link
G LOC101964209 C-C chemokine receptor type 1 ISO (PMID:21403648) UniProtKB PMID:21403648 NCBI chrNW_004936596:177,774...183,186 JBrowse link
G LOC101964456 ectonucleotide pyrophosphatase/phosphodiesterase family member 1 ISO (MGI:5607146|PMID:25479107), (MGI:6220772|PMID:30111653), (MGI:6294341|PMID:22510396) UniProt PMID:22510396, PMID:25479107, PMID:30111653 MGI:5607146, MGI:6220772, MGI:6294341 NCBI chrNW_004937067:194,375...246,607 JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 ISO (MGI:2178869|PMID:11790802) MGI PMID:11790802 MGI:2178869 NCBI chrNW_004936599:3,902,903...3,918,471 JBrowse link
G Mepe matrix extracellular phosphoglycoprotein ISO (MGI:5431257|PMID:22766095)
(MGI:2448336|PMID:12421822), (MGI:3851320|PMID:15843468)
MGI PMID:12421822, PMID:15843468, PMID:22766095 MGI:2448336, MGI:3851320, MGI:5431257 NCBI chrNW_004936905:284,849...297,297 JBrowse link
G Nfe2 nuclear factor, erythroid 2 ISO (MGI:3653541|PMID:15005853) MGI PMID:15005853 MGI:3653541 NCBI chrNW_004936512:11,490,521...11,493,655 JBrowse link
G Ptk2b protein tyrosine kinase 2 beta ISO (MGI:3713957|PMID:17537919) UniProt PMID:17537919 MGI:3713957 NCBI chrNW_004936675:216,970...325,670 JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (MGI:2135696|PMID:11371614) MGI PMID:11371614 MGI:2135696 NCBI chrNW_004936655:1,849,044...1,852,648 JBrowse link
G Srgn serglycin ISO (PMID:16870619) UniProtKB PMID:16870619 NCBI chrNW_004936521:9,319,114...9,332,655 JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23081848 RGD:10003033 NCBI chrNW_004936664:3,093,258...3,124,473 JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chrNW_004936673:1,394,743...1,399,726 JBrowse link
G Pth parathyroid hormone ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chrNW_004936528:5,081,569...5,084,030 JBrowse link
G Rflnb refilin B ISO (MGI:5570967|PMID:24436304) MGI PMID:24436304 MGI:5570967 NCBI chrNW_004936538:7,226,570...7,233,203 JBrowse link
negative regulation of tooth mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspn asporin ISO (MGI:3722035|PMID:17522060) UniProt PMID:17522060 MGI:3722035 NCBI chrNW_004936487:2,080,014...2,104,534 JBrowse link
G Bcor BCL6 corepressor ISO (PMID:19578371) UniProtKB PMID:19578371 NCBI chrNW_004936502:6,764,043...6,812,194 JBrowse link
otolith mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 ISO (MGI:1275896|PMID:9668038) MGI PMID:9668038 MGI:1275896 NCBI chrNW_004936602:2,744,757...3,011,051 JBrowse link
G Oc90 otoconin 90 ISO (MGI:5896790|PMID:21655225), (MGI:6189500|PMID:24748133) UniProt PMID:21655225, PMID:24748133 MGI:5896790, MGI:6189500 NCBI chrNW_004936470:17,072,435...17,099,520 JBrowse link
G Otol1 otolin 1 ISO (MGI:5896790|PMID:21655225), (MGI:6189500|PMID:24748133), (MGI:6189669|PMID:29076638) UniProt PMID:21655225, PMID:24748133, PMID:29076638 MGI:5896790, MGI:6189500, MGI:6189669 NCBI chrNW_004936708:1,417,801...1,426,386 JBrowse link
positive regulation of biomineral tissue development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amtn amelotin ISO (PMID:25407797) UniProtKB PMID:25407797 NCBI chrNW_004936598:4,204,094...4,210,492 JBrowse link
G Atf4 activating transcription factor 4 ISO (MGI:5812283|PMID:27812542) MGI PMID:27812542 MGI:5812283 NCBI chrNW_004936492:2,114,478...2,115,969 JBrowse link
G Fbxo5 F-box protein 5 ISO (PMID:29850565) UniProt PMID:29850565 NCBI chrNW_004936489:5,589,621...5,602,221 JBrowse link
G Odaph odontogenesis associated phosphoprotein ISO (PMID:22901946) UniProtKB PMID:22901946 NCBI chrNW_004936598:400,214...407,597 JBrowse link
positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004936469:20,743,195...20,811,567 JBrowse link
G Acvr2a activin A receptor type 2A ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004936469:29,195,329...29,273,237 JBrowse link
G Acvr2b activin A receptor type 2B ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004936473:27,816,366...27,822,555 JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 ISO (MGI:6211994|PMID:22419726) UniProt PMID:22419726 MGI:6211994 NCBI chrNW_004936469:8,653,031...9,209,840 JBrowse link
G Adrb2 adrenoceptor beta 2 ISO (MGI:3575849|PMID:15724149) MGI PMID:15724149 MGI:3575849 NCBI chrNW_004936504:5,985,407...5,987,453 JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO (MGI:6393219|PMID:24906289) UniProt PMID:24906289 MGI:6393219 NCBI chrNW_004936554:7,807,914...7,848,691 JBrowse link
G Ano6 anoctamin 6 ISO (PMID:25589784)
(MGI:5634871|PMID:25589784)
UniProtKB
UniProt
PMID:25589784 MGI:5634871 NCBI chrNW_004936512:3,649,103...3,736,274 JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 ISO (MGI:5780494|PMID:26392310) UniProt PMID:26392310 MGI:5780494 NCBI chrNW_004936507:6,525,302...6,631,003 JBrowse link
G Atraid all-trans retinoic acid induced differentiation factor ISO (PMID:21723284) UniProtKB PMID:21723284 NCBI chrNW_004936493:5,333,151...5,338,157 JBrowse link
G Bmp2 bone morphogenetic protein 2 ISO (PMID:18436533), (PMID:20576608)
(MGI:5009350|PMID:20675382)
BHF-UCL PMID:18436533, PMID:20576608, PMID:20675382 MGI:5009350 NCBI chrNW_004936485:12,428,765...12,439,570 JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO (PMID:14749725), (PMID:18436533) RGD
UniProtKB
PMID:14749725, PMID:15352071, PMID:18436533 RGD:9068399 NCBI chrNW_004936697:1,054,237...1,061,468 JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004936534:4,707,658...4,871,865 JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004936530:71,965...143,940 JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004936804:52,435...115,289 JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004936687:2,346,601...2,595,283 JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004936726:1,543,263...1,711,422 JBrowse link
G Ccn1 cellular communication network factor 1 ISO (PMID:20675382) BHF-UCL PMID:20675382 NCBI chrNW_004936608:152,174...155,123 JBrowse link
G Cd276 CD276 molecule ISO (MGI:3052626|PMID:15317945) MGI PMID:15317945 MGI:3052626 NCBI chrNW_004936471:32,864,778...32,892,044 JBrowse link
G Fam20c FAM20C golgi associated secretory pathway kinase ISO (MGI:3715055|PMID:17369251), (MGI:5427766|PMID:22615579) MGI PMID:17369251, PMID:22615579 MGI:3715055, MGI:5427766 NCBI chrNW_004936754:596,878...649,585 JBrowse link
G Fbn2 fibrillin 2 ISO (MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:4836762 NCBI chrNW_004936504:1,535,629...1,757,386 JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO (MGI:4437389|PMID:20053668) MGI PMID:20053668 MGI:4437389 NCBI chrNW_004936477:21,591,772...21,606,289 JBrowse link
G Fzd9 frizzled class receptor 9 ISO (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chrNW_004936543:2,707,846...2,709,819 JBrowse link
G Gpm6b glycoprotein M6B ISO (PMID:21638316) UniProtKB PMID:21638316 NCBI chrNW_004936470:3,332,856...3,496,178 JBrowse link
G Isg15 ISG15 ubiquitin like modifier ISO (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chrNW_004936737:2,043,383...2,044,761 JBrowse link
G Kl klotho ISO (PMID:12110410) UniProtKB PMID:12110410 NCBI chrNW_004936472:27,604,681...27,649,613 JBrowse link
G Mef2c myocyte enhancer factor 2C ISO (MGI:5285459|PMID:21652706) UniProt PMID:21652706 MGI:5285459 NCBI chrNW_004936469:7,060,480...7,225,497 JBrowse link
G Nell1 neural EGFL like 1 ISO (PMID:21723284) UniProtKB PMID:21723284 NCBI chrNW_004936654:1,591,016...2,392,496 JBrowse link
G Osr1 odd-skipped related transcription factor 1 ISO (MGI:4950000|PMID:21262216) BHF-UCL PMID:21262216 MGI:4950000 NCBI chrNW_004936493:11,888,024...11,895,058 JBrowse link
G Osr2 odd-skipped related transciption factor 2 ISO (MGI:4950000|PMID:21262216) BHF-UCL PMID:21262216 MGI:4950000 NCBI chrNW_004936470:44,024,497...44,032,429 JBrowse link
G P2rx7 purinergic receptor P2X 7 ISO (MGI:2667237|PMID:12677010), (MGI:3797675|PMID:18519738) MGI PMID:12677010, PMID:18519738 MGI:2667237, MGI:3797675 NCBI chrNW_004936558:3,106,819...3,149,689 JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic ISO (MGI:3813934|PMID:19097194) UniProt PMID:19097194 MGI:3813934 NCBI chrNW_004936508:9,550,201...9,559,493 JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chrNW_004936481:3,559,377...3,689,797 JBrowse link
G Pth parathyroid hormone ISO (PMID:17696759) RGD
UniProtKB
PMID:15758479, PMID:17696759, PMID:22445539 RGD:7207452, RGD:7242906 NCBI chrNW_004936528:5,081,569...5,084,030 JBrowse link
G Ptn pleiotrophin ISO (MGI:6294181|PMID:19442624) UniProt PMID:19442624 MGI:6294181 NCBI chrNW_004936592:1,706,979...1,806,345 JBrowse link
G Slc8a1 solute carrier family 8 member A1 ISO (PMID:25589784) UniProtKB PMID:25589784 NCBI chrNW_004936508:10,894,918...11,256,084 JBrowse link
G Smad3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chrNW_004936471:27,080,662...27,185,861 JBrowse link
G Tfap2a transcription factor AP-2 alpha ISO (PMID:19578371) UniProtKB PMID:19578371 NCBI chrNW_004936534:2,481,804...2,518,573 JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO (PMID:17401695) BHF-UCL PMID:17401695 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Tgfb3 transforming growth factor beta 3 ISO (PMID:17401695) BHF-UCL PMID:17401695 NCBI chrNW_004936488:4,986,712...5,008,728 JBrowse link
G Tmem119 transmembrane protein 119 ISO (PMID:20025746)
(MGI:4418582|PMID:20025746), (MGI:5700277|PMID:26207632)
UniProtKB
UniProt
PMID:20025746, PMID:26207632 MGI:4418582, MGI:5700277 NCBI chrNW_004936769:513,695...515,769 JBrowse link
G Wnt10b Wnt family member 10B ISO (MGI:3574150|PMID:15728361) MGI PMID:15728361 MGI:3574150 NCBI chrNW_004936512:6,768,240...6,774,172 JBrowse link
G Wnt4 Wnt family member 4 ISO (PMID:17720811) BHF-UCL PMID:17720811 NCBI chrNW_004936474:7,623,462...7,635,416 JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 ISO (MGI:5291888|PMID:21784188) UniProt PMID:21784188 MGI:5291888 NCBI chrNW_004936599:3,033,854...3,046,364 JBrowse link
G Asxl2 ASXL transcriptional regulator 2 ISO (MGI:5514358|PMID:21490954) MGI PMID:21490954 MGI:5514358 NCBI chrNW_004936493:6,463,771...6,602,244 JBrowse link
positive regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amtn amelotin ISO (MGI:5613837|PMID:25407797) UniProt PMID:25407797 MGI:5613837 NCBI chrNW_004936598:4,204,094...4,210,492 JBrowse link
G Dspp dentin sialophosphoprotein ISO (MGI:3603472|PMID:16014627) MGI PMID:16014627 MGI:3603472 NCBI chrNW_004936905:458,062...463,359 JBrowse link
G Enam enamelin ISO (MGI:5647983|PMID:24603688) MGI PMID:24603688 MGI:5647983 NCBI chrNW_004936598:4,118,031...4,132,342 JBrowse link
G Odaph odontogenesis associated phosphoprotein ISO (PMID:22901946) UniProtKB PMID:22901946 NCBI chrNW_004936598:400,214...407,597 JBrowse link
positive regulation of tooth mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tfap2a transcription factor AP-2 alpha ISO (PMID:19578371) UniProtKB PMID:19578371 NCBI chrNW_004936534:2,481,804...2,518,573 JBrowse link
G Wnt6 Wnt family member 6 ISO (PMID:20113781) BHF-UCL PMID:20113781 NCBI chrNW_004936569:1,290,061...1,302,672 JBrowse link
regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankh ANKH inorganic pyrophosphate transport regulator ISO (MGI:1860991|PMID:10894769), (MGI:55055|PMID:7276519) MGI PMID:7276519, PMID:10894769 MGI:1860991, MGI:55055 NCBI chrNW_004936665:1,520,800...1,654,388 JBrowse link
G Bmp2k BMP2 inducible kinase ISO (MGI:2153232|PMID:11500515) MGI PMID:11500515 MGI:2153232 NCBI chrNW_004936676:2,361,878...2,496,006 JBrowse link
G Comp cartilage oligomeric matrix protein ISO (MGI:5318950|PMID:21350216) MGI PMID:21350216 MGI:5318950 NCBI chrNW_004936596:2,544,389...2,551,155 JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO (PMID:20564243) UniProtKB PMID:20564243 NCBI chrNW_004936831:799,948...946,139 JBrowse link
G Ecm1 extracellular matrix protein 1 ISO (MGI:4452294|PMID:20138147) MGI PMID:20138147 MGI:4452294 NCBI chrNW_004936580:750,423...756,765 JBrowse link
G Fgf23 fibroblast growth factor 23 ISO (MGI:3510566|PMID:15579309) MGI PMID:15579309 MGI:3510566 NCBI chrNW_004936606:4,555,034...4,561,961 JBrowse link
G LOC101978323 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial ISO (PMID:9415400) BHF-UCL PMID:9415400 NCBI chrNW_004936646:1,899,686...1,904,104 JBrowse link
G Matn1 matrilin 1 ISO (MGI:3655339|PMID:16877353) MGI PMID:16877353 MGI:3655339 NCBI chrNW_004936474:14,085,240...14,093,364 JBrowse link
G Nbr1 NBR1 autophagy cargo receptor ISO (MGI:4818844|PMID:20616007) BHF-UCL PMID:20616007 MGI:4818844 NCBI chrNW_004936490:17,803,074...17,832,349 JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 ISO (MGI:3839226|PMID:19204730) UniProt PMID:19204730 MGI:3839226 NCBI chrNW_004936748:1,244,962...1,250,093 JBrowse link
G Sgms2 sphingomyelin synthase 2 ISO (PMID:30779713) UniProt PMID:30779713 NCBI chrNW_004936818:687,695...726,123 JBrowse link
G Suv39h1 suppressor of variegation 3-9 homolog 1 ISO (MGI:5913114|PMID:23695662) MGI PMID:23695662 MGI:5913114 NCBI chrNW_004936721:646,778...661,144 JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:19597909) BHF-UCL PMID:19597909 NCBI chrNW_004936546:5,331,220...5,332,669 JBrowse link
G Txlng taxilin gamma ISO (MGI:3587454|PMID:15911876), (MGI:5306578|PMID:19016261) UniProt PMID:15911876, PMID:19016261 MGI:3587454, MGI:5306578 NCBI chrNW_004936470:6,054,076...6,107,613 JBrowse link
G Zmpste24 zinc metallopeptidase STE24 ISO (MGI:5913114|PMID:23695662) MGI PMID:23695662 MGI:5913114 NCBI chrNW_004936474:22,035,059...22,077,846 JBrowse link
regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1, ribonuclease III ISO (MGI:4453947|PMID:20102707) MGI PMID:20102707 MGI:4453947 NCBI chrNW_004936846:528,768...584,599 JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 ISO (MGI:3603472|PMID:16014627) MGI PMID:16014627 MGI:3603472 NCBI chrNW_004936905:419,478...427,335 JBrowse link
tooth mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amelx amelogenin X-linked ISO (PMID:1483698)
(MGI:2149207|PMID:11406633)
BHF-UCL PMID:1483698, PMID:11406633 MGI:2149207 NCBI chrNW_004936470:1,169,906...1,174,166 JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO (PMID:17118335) UniProtKB PMID:17118335 NCBI chrNW_004936490:11,448,552...11,465,836 JBrowse link
G Tspear thrombospondin type laminin G domain and EAR repeats ISO (PMID:27736875) UniProt PMID:27736875 NCBI chrNW_004936778:1,576,580...1,660,344 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12002
    biomineralization 156
      biomineral tissue development 154
        bone mineralization + 119
        chitin-based cuticle sclerotization by biomineralization 0
        negative regulation of biomineral tissue development + 27
        otolith mineralization + 3
        positive regulation of biomineral tissue development + 51
        regulation of biomineral tissue development + 91
        shell calcification + 0
        tooth mineralization + 27
Path 2
Term Annotations click to browse term
  biological_process 12002
    developmental process 5648
      anatomical structure development 5286
        multicellular organism development 4845
          system development 4567
            animal organ development 3514
              biomineral tissue development 154
                bone mineralization + 119
                chitin-based cuticle sclerotization by biomineralization 0
                negative regulation of biomineral tissue development + 27
                otolith mineralization + 3
                positive regulation of biomineral tissue development + 51
                regulation of biomineral tissue development + 91
                shell calcification + 0
                tooth mineralization + 27
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.