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ONTOLOGY REPORT - ANNOTATIONS


Term:DNA replication preinitiation complex
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Accession:GO:0031261 term browser browse the term
Definition:A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present.
Synonyms:exact_synonym: pre-IC


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DNA replication preinitiation complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc45 cell division cycle 45 JBrowse link 11 86,328,785 86,354,099 RGD:13792537
G Orc3 origin recognition complex, subunit 3 JBrowse link 5 50,019,159 50,075,533 RGD:13792537
GINS complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gins1 GINS complex subunit 1 JBrowse link 3 146,695,366 146,716,787 RGD:13792537
G Gins2 GINS complex subunit 2 JBrowse link 19 54,151,048 54,163,701 RGD:13792537
G Gins4 GINS complex subunit 4 JBrowse link 16 73,584,412 73,596,808 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19738
    cellular anatomical entity 19354
      nucleoplasm 3364
        DNA replication preinitiation complex 5
          CMG complex 0
          GINS complex 3
Path 2
Term Annotations click to browse term
  cellular_component 19738
    cellular anatomical entity 19354
      organelle 12457
        intracellular organelle 11936
          intracellular membrane-bounded organelle 9924
            nucleus 6747
              nuclear lumen 3991
                nucleoplasm 3364
                  DNA replication preinitiation complex 5
                    CMG complex 0
                    GINS complex 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.